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0  structures 131  species 0  interactions 2126  sequences 65  architectures

Family: NAM-associated (PF14303)

Summary: No apical meristem-associated C-terminal domain

Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.

The Pfam group coordinates the annotation of Pfam families in Wikipedia, but we have not yet assigned a Wikipedia article to this family. If you think that a particular Wikipedia article provides good annotation, please let us know.

This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.

No apical meristem-associated C-terminal domain Provide feedback

This domain is found in a number of different types of plant proteins including NAM-like proteins.

Internal database links

This tab holds annotation information from the InterPro database.

InterPro entry IPR029466

This domain is found in a number of fungal and plant proteins including NAM (no apical meristem)-like proteins.

Domain organisation

Below is a listing of the unique domain organisations or architectures in which this domain is found. More...

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Pfam Clan

This family is a member of clan KA1-like (CL0573), which has the following description:

This superfamily is characterised by small adenylate-sensing domains at the C-terminus of molecules such as AMP-Activated Protein Kinases an SNF1-like protein kinases [1].

The clan contains the following 4 members:

AdenylateSensor KA1 NAF NAM-associated

Alignments

We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets and the UniProtKB sequence database. More...

View options

We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(53)
Full
(2126)
Representative proteomes UniProt
(3269)
RP15
(257)
RP35
(1027)
RP55
(1897)
RP75
(2242)
Jalview View  View  View  View  View  View  View 
HTML View  View           
PP/heatmap 1 View           

1Cannot generate PP/Heatmap alignments for seeds; no PP data available

Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(53)
Full
(2126)
Representative proteomes UniProt
(3269)
RP15
(257)
RP35
(1027)
RP55
(1897)
RP75
(2242)
Alignment:
Format:
Order:
Sequence:
Gaps:
Download/view:

Download options

We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(53)
Full
(2126)
Representative proteomes UniProt
(3269)
RP15
(257)
RP35
(1027)
RP55
(1897)
RP75
(2242)
Raw Stockholm Download   Download   Download   Download   Download   Download   Download  
Gzipped Download   Download   Download   Download   Download   Download   Download  

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

HMM logo

HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...

Trees

This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.

Note: You can also download the data file for the tree.

Curation and family details

This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.

Curation View help on the curation process

Seed source: Jackhmmer:Q9SKG8
Previous IDs: none
Type: Family
Sequence Ontology: SO:0100021
Author: Coggill P
Number in seed: 53
Number in full: 2126
Average length of the domain: 140.40 aa
Average identity of full alignment: 16 %
Average coverage of the sequence by the domain: 44.54 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 27.7 27.7
Trusted cut-off 27.7 27.7
Noise cut-off 27.6 27.6
Model length: 165
Family (HMM) version: 8
Download: download the raw HMM for this family

Species distribution

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Colour assignments

Archea Archea Eukaryota Eukaryota
Bacteria Bacteria Other sequences Other sequences
Viruses Viruses Unclassified Unclassified
Viroids Viroids Unclassified sequence Unclassified sequence

Selections

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This visualisation provides a simple graphical representation of the distribution of this family across species. You can find the original interactive tree in the adjacent tab. More...

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Tree controls

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The tree shows the occurrence of this domain across different species. More...

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Please note: for large trees this can take some time. While the tree is loading, you can safely switch away from this tab but if you browse away from the family page entirely, the tree will not be loaded.

AlphaFold Structure Predictions

The list of proteins below match this family and have AlphaFold predicted structures. Click on the protein accession to view the predicted structure.

Protein Predicted structure External Information
A0A0N7KD49 View 3D Structure Click here
A0A0N7KMG6 View 3D Structure Click here
A0A0N7KTM8 View 3D Structure Click here
A0A0N7KTS3 View 3D Structure Click here
A0A0P0UYZ8 View 3D Structure Click here
A0A0P0VAY6 View 3D Structure Click here
A0A0P0VJ50 View 3D Structure Click here
A0A0P0VZT9 View 3D Structure Click here
A0A0P0W156 View 3D Structure Click here
A0A0P0WDW8 View 3D Structure Click here
A0A0P0WSA3 View 3D Structure Click here
A0A0P0X038 View 3D Structure Click here
A0A0P0X0Z5 View 3D Structure Click here
A0A0P0X8A8 View 3D Structure Click here
A0A0P0XCK0 View 3D Structure Click here
A0A0P0XH65 View 3D Structure Click here
A0A0P0XLZ8 View 3D Structure Click here
A0A0P0XXV4 View 3D Structure Click here
A0A0P0Y8S5 View 3D Structure Click here
A0A0R0EJ60 View 3D Structure Click here
A0A0R0EJW0 View 3D Structure Click here
A0A0R0FE63 View 3D Structure Click here
A0A0R0FNC4 View 3D Structure Click here
A0A0R0FPB0 View 3D Structure Click here
A0A0R0GI64 View 3D Structure Click here
A0A0R0HT93 View 3D Structure Click here
A0A0R0IDV1 View 3D Structure Click here
A0A0R0IJK1 View 3D Structure Click here
A0A0R0J409 View 3D Structure Click here
A0A0R0JAX5 View 3D Structure Click here
A0A0R0JJ82 View 3D Structure Click here
A0A0R0JPZ0 View 3D Structure Click here
A0A0R0K783 View 3D Structure Click here
A0A0R0K866 View 3D Structure Click here
A0A0R0LE70 View 3D Structure Click here
A0A1D6DUY4 View 3D Structure Click here
A0A1D6ECZ1 View 3D Structure Click here
A0A1D6EP48 View 3D Structure Click here
A0A1D6F6X3 View 3D Structure Click here
A0A1D6F7Q3 View 3D Structure Click here
A0A1D6FQ71 View 3D Structure Click here
A0A1D6H6L9 View 3D Structure Click here
A0A1D6HF05 View 3D Structure Click here
A0A1D6IBD3 View 3D Structure Click here
A0A1D6JFM1 View 3D Structure Click here
A0A1D6JZK6 View 3D Structure Click here
A0A1D6JZK6 View 3D Structure Click here
A0A1D6KWT0 View 3D Structure Click here
A0A1D6LQ32 View 3D Structure Click here
A0A1D6LY54 View 3D Structure Click here
A0A1D6MXY4 View 3D Structure Click here
A0A1D6MZR4 View 3D Structure Click here
A0A1D6NL05 View 3D Structure Click here
A0A1D6PAS0 View 3D Structure Click here
A0A1D6QKU4 View 3D Structure Click here
B4FSZ0 View 3D Structure Click here
C7J6X0 View 3D Structure Click here
C7J9P3 View 3D Structure Click here
F4ID96 View 3D Structure Click here
O82618 View 3D Structure Click here
Q0ITA8 View 3D Structure Click here
Q0JEE5 View 3D Structure Click here
Q2R3L6 View 3D Structure Click here
Q5Z5G1 View 3D Structure Click here
Q5Z5P3 View 3D Structure Click here
Q6AVB6 View 3D Structure Click here
Q6YYW9 View 3D Structure Click here
Q7F0Z6 View 3D Structure Click here
Q8S0Y0 View 3D Structure Click here
Q9FYM4 View 3D Structure Click here
Q9SKG8 View 3D Structure Click here
Q9STU5 View 3D Structure Click here

trRosetta Structure

The structural model below was generated by the Baker group with the trRosetta software using the Pfam UniProt multiple sequence alignment.

The InterPro website shows the contact map for the Pfam SEED alignment. Hovering or clicking on a contact position will highlight its connection to other residues in the alignment, as well as on the 3D structure.

Improved protein structure prediction using predicted inter-residue orientations. Jianyi Yang, Ivan Anishchenko, Hahnbeom Park, Zhenling Peng, Sergey Ovchinnikov, David Baker Proceedings of the National Academy of Sciences Jan 2020, 117 (3) 1496-1503; DOI: 10.1073/pnas.1914677117;