Summary: Leucine-zipper of ternary complex factor MIP1
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Leucine-zipper of ternary complex factor MIP1 Provide feedback
This leucine-zipper is towards the N-terminus of MIP1 proteins. These proteins, here largely from plants, are subunits of the TORC2 (rictor-mTOR) protein complex controlling cell growth and proliferation . The leucine-zipper is likely to be the region that interacts with plant MADS-box factors 
Causier B, Cook H, Davies B;, Plant Mol Biol. 2003;52:1051-1062.: An antirrhinum ternary complex factor specifically interacts with C-function and SEPALLATA-like MADS-box factors. PUBMED:14558664 EPMC:14558664
Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B;, Cell. 2006;127:125-137.: SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. PUBMED:16962653 EPMC:16962653
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This tab holds annotation information from the InterPro database.
InterPro entry IPR025757
This leucine-zipper domain can be found in MIP1 proteins and in putative Rho GTPase-activating proteins. MIP1 proteins, here largely from plants, are subunits of the TORC2 (rictor-mTOR) protein complex controlling cell growth and proliferation [PUBMED:16962653]. The leucine-zipper is likely to be the region that interacts with plant MADS-box factors [PUBMED:14558664],
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Curation and family details
|Number in seed:||39|
|Number in full:||340|
|Average length of the domain:||83.90 aa|
|Average identity of full alignment:||31 %|
|Average coverage of the sequence by the domain:||13.80 %|
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build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||1|
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