Summary: Ribosomally synthesized peptide in Streptomyces species
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Ribosomally synthesized peptide in Streptomyces species Provide feedback
A ribosomally synthesized peptide related to microviridin and marinostatin, usually in the gene neighborhood of one or more RimK-like ATP-grasp. The gene-context suggests that it is further modified by the ATP-grasp. The peptide is predicted to function in a defensive or developmental role, or as an antibiotic .
Iyer LM, Abhiman S, Maxwell Burroughs A, Aravind L;, Mol Biosyst. 2009;5:1636-1660.: Amidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferase-like domains: synthesis of novel metabolites and peptide modifications of proteins. PUBMED:20023723 EPMC:20023723
This tab holds annotation information from the InterPro database.
InterPro entry IPR025744
This family consists of ribosomally synthesised peptides from Streptomyces species and related to microviridin and marinostatin. They are usually in the gene neighbourhood of one or more RimK-like ATP-grasp. The gene-context suggests that it is further modified by the ATP-grasp. The peptide is predicted to function in a defensive or developmental role, or as an antibiotic [PUBMED:20023723].
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Curation and family details
|Author:||Iyer LM, Abhiman S, Burroughs AM, Aravind L|
|Number in seed:||8|
|Number in full:||65|
|Average length of the domain:||62.50 aa|
|Average identity of full alignment:||72 %|
|Average coverage of the sequence by the domain:||99.56 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||5|
|Download:||download the raw HMM for this family|
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