Summary: 28 kDa A-kinase anchor
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28 kDa AKAP (AKAP28) is highly enriched in human airway axonemes. The mRNA for AKAP28 is up-regulated as primary airway cells differentiate and is specifically expressed in tissues containing cilia and/or flagella . Homologs of AKAP28 are present in all animals and in some, including mice the AKAP28-like domain are preceded by another uncharacterized domain
Kultgen,P.L., Byrd,S.K., Ostrowski,L.E. and Milgram,S.L., Mol Biol Cell. 2002 Dec;13(12):4156-66.: Characterization of an A-kinase anchoring protein in human ciliary axonemes PUBMED:12475942 EPMC:12475942
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This tab holds annotation information from the InterPro database.
InterPro entry IPR025663
28 kDa AKAP (AKAP28) is highly enriched in human airway axonemes. The mRNA for AKAP28 is up-regulated as primary airway cells differentiate and is specifically expressed in tissues containing cilia and/or flagella [PUBMED:12475942]. Homologs of AKAP28 are present in all animals.
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Curation and family details
|Seed source:||Q86UN6 A-kinase anchor protein 14 isoform a [Homo sapiens]|
|Author:||Jaroszewski L, Godzik A|
|Number in seed:||15|
|Number in full:||76|
|Average length of the domain:||111.90 aa|
|Average identity of full alignment:||30 %|
|Average coverage of the sequence by the domain:||49.52 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||1|
|Download:||download the raw HMM for this family|
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