# STOCKHOLM 1.0
#=GF ID   NrfD_2
#=GF AC   PF14589.5
#=GF DE   Polysulfide reductase
#=GF AU   Coggill P
#=GF SE   CATH:2vpzC00, Pfam-B_200168
#=GF GA   27.00 27.00;
#=GF TC   27.50 28.10;
#=GF NC   25.30 26.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   18536726
#=GF RT   Molecular mechanism of energy conservation in polysulfide
#=GF RT   respiration.
#=GF RA   Jormakka M, Yokoyama K, Yano T, Tamakoshi M, Akimoto S,
#=GF RA   Shimamura T, Curmi P, Iwata S;
#=GF RL   Nat Struct Mol Biol. 2008;15:730-737.
#=GF DR   INTERPRO; IPR032796;
#=GF CC   Bacterial polysulfide reductase is an integral membrane protein
#=GF CC   complex responsible for quinone-coupled reduction of
#=GF CC   polysulfide, a process important in extreme environments such as
#=GF CC   deep-sea vents and hot springs. Polysulfides are a class of
#=GF CC   compounds composed of chains of sulfur atoms, which in their
#=GF CC   simplest form are present as an anion with general formula
#=GF CC   Sn(2-). In nature, polysulfides are found in particularly high
#=GF CC   concentrations in extreme volcanic or geothermically active
#=GF CC   environments. Here, the reduction and oxidation of polysulfides
#=GF CC   are vital processes for many bacteria and are essential steps in
#=GF CC   the global sulfur cycle. In particular, the reduction of
#=GF CC   polysulfide to hydrogen sulfide in these environments is usually
#=GF CC   linked to energy-generating respiratory processes, supporting
#=GF CC   growth of many microorganisms, particularly hyperthermophiles.
#=GF SQ   2
#=GS E4U7V7_OCEP5/1-254  AC E4U7V7.1
#=GS E4U7K8_OCEP5/1-265  AC E4U7K8.1
E4U7V7_OCEP5/1-254             MTGEWGIYIVLYFW..........LAAMGGGAFLIA.LGLRDERARRSGAFLAFIGIVIGALLLIVDLGQPVRFWH..LLVGFHPISVMWLGSAVLALSGLGLFLLLV....MREWPGWLVWVTAILVLLVVGYTGVLLMA.TARPFWSGSPLMPWIFLASAYTTGAALLVLLGNRE...PGLHRISFNFALIEIVLVVAHLIWTYP..LAKNAVQAALTGELAWAFWGFVVLGVALPLYMEA..QRRAASLAALLVLAGGFLLRYFIVYAGQTG..VLRF
E4U7K8_OCEP5/1-265             MTTFYGLPGAEAFWHWTTLVHFLLVALAGGTAFYTAVLGIRRAASARGLAWLALAFIVLDLFMLWAESPARFRFSHVWLFLSFEPASAIWWGAWGLATSALMLLLLALGLGPARFWAGVLALTSAV....VLAYPGYALAANAARPLW..DHLLLAFFPASGLLLALAVLVWLRPAEEAAPWLQVA....ALASLALAA.....LYPVALASGGADARLAFALWLRGWGWFLLGGGL.LFLAAFLARRAPALAGACALAGAFVLRSWIVEQGQHSFFVHGF
#=GC seq_cons                  MTs.aGl.hs.hFW..........lAhhGGsAFhhA.LGlRcttutRuhAaLAhhhIVlshhhLhs-.st.hRF.H..LhluFcPhSshWhGuhsLAhSuLhLhLLhl....hR.WsGhLshsoAl....VluYsGhhLhA.sARPhW..s.Lh.hhF.ASuhhhuhAlLVhLtstE...PhLphh....ALhplsLss.....hYP..LApsuspAtLshtLhhthWGahlLGsuL.LahtA..tRRAsuLAuhhsLAGuFlLR.aIV.tGQpu..VhtF
//