# STOCKHOLM 1.0
#=GF ID   ARGLU
#=GF AC   PF15346.7
#=GF DE   Arginine and glutamate-rich 1
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:Q9NWB6
#=GF GA   27.00 27.00;
#=GF TC   28.40 28.40;
#=GF NC   26.70 25.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Coiled-coil
#=GF RN   [1]
#=GF RM   21454576
#=GF RT   Arginine and glutamate-rich 1 (ARGLU1) interacts with mediator
#=GF RT   subunit 1 (MED1) and is required for estrogen receptor-mediated
#=GF RT   gene transcription and breast cancer cell growth.
#=GF RA   Zhang D, Jiang P, Xu Q, Zhang X;
#=GF RL   J Biol Chem. 2011;286:17746-17754.
#=GF DR   INTERPRO; IPR033371;
#=GF DR   SO; 0001080; coiled_coil;
#=GF CC   ARGLU, arginine and glutamate-rich 1 protein family, is required
#=GF CC   for the oestrogen-dependent expression of ESR1 target genes. It
#=GF CC   functions in cooperation with MED1. The family of proteins is
#=GF CC   found in eukaryotes.
#=GF SQ   17
#=GS H9J9G0_BOMMO/606-756     AC H9J9G0.1
#=GS B4Q8A3_DROSI/16-166      AC B4Q8A3.1
#=GS E9GZN0_DAPPU/65-215      AC E9GZN0.1
#=GS A8X3B7_CAEBR/103-243     AC A8X3B7.1
#=GS B7PMR2_IXOSC/4-166       AC B7PMR2.1
#=GS G4V7R8_SCHMA/73-223      AC G4V7R8.1
#=GS A0A068XX38_ECHMU/62-212  AC A0A068XX38.1
#=GS D8U2Q3_VOLCA/251-403     AC D8U2Q3.1
#=GS D8RY35_SELML/58-213      AC D8RY35.1
#=GS D7KLK5_ARALL/75-230      AC D7KLK5.1
#=GS M0RJM7_MUSAM/113-267     AC M0RJM7.1
#=GS M4CX87_BRARP/82-237      AC M4CX87.1
#=GS C3ZEM5_BRAFL/116-266     AC C3ZEM5.1
#=GS W4XZ24_STRPU/137-287     AC W4XZ24.1
#=GS F6X2R6_CIOIN/56-206      AC F6X2R6.1
#=GS K1RBE7_CRAGI/63-213      AC K1RBE7.1
#=GS T1F0Z7_HELRO/106-256     AC T1F0Z7.1
H9J9G0_BOMMO/606-756                REAEQKVVEEEAAKRIELLVKKRVEEELEKRKDEIELEVAKRVEEAKRKMEKEMMEELEKQREQQRREEQARQ............EEETRKRKELEDIMAENNKKIEEAQRKLA.......EERLAMIEEQRKMDEERQKLKKEQEKRIKEEQKKILGKN.NSRPKLSFSL
B4Q8A3_DROSI/16-166                 KELEQKTIEEEAAKRIEMLVKKRVEEELEKRRDEIEQEVNRRVETAKAEMEREMMLELERRREQIREEERRRE............EDEKQKREELEEILAENNRKIEEAQRKLA.......EERLAIIEEQRLMDEERQRMRKEQEKRVKEEQKVILGKN.NSRPKLSFSL
E9GZN0_DAPPU/65-215                 KEQEQKIVEEETVKRIEEMVAQRVAEELEKRKDEIEAEVLRRVEEAKQIMERQMLEELERRRKERLEEENRRE............EEERRKREELERIVEENNKKIEEAQRKLA.......EERLAMVEQSRKMEEDRQRMQREHEKRMRDEQYLILGKK.NARPKLSFSL
A8X3B7_CAEBR/103-243                .......LNDPTKRWLEEKIVEQVTARVH....QLEAMMAEKATSARNEMEKMLRAQIEAEMAVELAECKKRD............EESRKKCKQLEAELERKVLEAEESRKKFE.......EDRLAMLEQKGQLERDRADLARQKSELQKNEQQAILNKSGNARAPIKFKF
B7PMR2_IXOSC/4-166                  KEVDSKKAEDDMHRRIEEAVAMRVQEEMERRKEAMETEVRRRVEEARHHMEKQLMQEIEQRRSQMMAEHKLKEVGPTVLGRSSRNEEERKRLQELERTLEENSRKLEEAQRKLA.......EERLAMVEERRRLDEARRKLEQEQEKKMRQDQQVILNKG.KVRPKLSFSL
G4V7R8_SCHMA/73-223                 RWAESKLLEEEVARRLERYLDSELAKLLVLRRVQFNAEIERRVEAERTEVLRRRAEEAERKAKEEAEALQRRE............EEEKRLKEVSERLAQERERELEEQRRLEE.......EAERKRCEAELRELEERQRREAEELQRIKREQEIILNKK.RIRPKLSFTL
A0A068XX38_ECHMU/62-212             QWAESKLLEEEVARRLERYLEAELAVLLKEREAEFNAEVERRVAIEREALEKRRKEEAERKAREEEEEKHRKE............EEERQLKELNERLARQREEELSELRRKEE.......EVRQKQYEEELRKLEEKQRLEAEEQRRIKKEQEIILNRK.RVRPKLSFTL
D8U2Q3_VOLCA/251-403                .ELQSRLVAEELERRVAAYVEERVAAVLN..SEAVQRELQTRLERERRAIEEQVERELVAERERAAREEEARR............EAIRAQQQELEELELERKKEEEEAAKRRREEEARQLEQHFLELQRKQQAKMEEEERKKKEDEDLKRQQQLILGKG...RKKMSFSL
D8RY35_SELML/58-213                 QEAELKLIEEETTRRVDEAIRKRVQEVLD..SDEIQKEIQMRIDEGRKKMIEDVNAQLAREREAALRATRTKE............EQERKDKEDLDRMLEENKRKVEEAQKREAEERARKEEERYRELEAIQRQKDEIMRRRKLEEELEREEQMKILGKK.NARPKLSFAL
D7KLK5_ARALL/75-230                 QEAELKLIEEETVKRVEEAIRKKIEESLQ..SEKIKLEILTLLEEGRKRLDEEVAAQLEKEKEASLIEAKEKE............EREQQEKEESERIAEENLKRVEEAQRKEAMERQRKEEERYRELEELQRQKEEAMRRKKAEEEEERLKQMKLLGKN.KSRPKLSFAL
M0RJM7_MUSAM/113-267                KEAELRILEEETARRIEEAIRKKVEESLN..SEEIKLEIQRRIEEGHKKLLDEVAAQLEKEKEAALIEARQKA............EQERKEREELDKMLEENQRRVEESQRREALEQQQKELERCLELEHLQKEKEEAMRRKKMWEEEEKANQMKLLGKN.KSRPKLSFA.
M4CX87_BRARP/82-237                 HEAELKRLEEETARRIEEAVRKNVEERMN..TEEVKEEIERRTKEAYEKMLLDVEIQLKNEKQSALNEARRKE............EQARREREELDKMLEENSRRVEESQRREALELQRKEEERYRELELIQRQKEEAARRKKLEEEEEIRNSSKVSNGS.RSRSKLHFGM
C3ZEM5_BRAFL/116-266                QEIEARLVEEEVAKRVEEMVAKRVEEELEKRKDEIEREVLRRVEEAKKIMEQQMLEEMERQRNAEVEAQRLKE............EEESKKRAELERIMIENNRKIEEAQQKLA.......EERLKMIEEQRKIHEEKLAYEREKMKQVKEEQNVVLNKK.NSRPKLSFSL
W4XZ24_STRPU/137-287                QEMEAKLIEEEVTRRVEEMVAQRVEEELEKRKDDIEEEVGRRVEEAKKIMEKEMMEEMEKQREAEVAAQKAKE............EEELDKREALEKIMHENQRKIEEAQRKLA.......EERLEMVERQRKMDEERQAFEREQKRRHKAEQEVILNKK.SSRPKLSFGF
F6X2R6_CIOIN/56-206                 KELEEKMIEDETAKRVEELVKKRVEEELEKRKDEIEKEVLRRVEEMKHIMEKQMLEEMERQKLAELQARQAKE............EEETQKRTQLEEILKENDRKMKEAEERMN.......EERLAMVEQQRLIHEERMRMEEDRKKQRRAEQNVILGKK.NTRPKLSFSL
K1RBE7_CRAGI/63-213                 KELEEKLIEEEVARRVEELVAKRVEEELERRKDEIEAEVRRRVEEAKKIMEKQMLEELERQREAELEAQKKKE............EEEKLKRKELEEIMAENNKKIEEAQKKLA.......EEQLKLVEEQRRMLEEKQRMEEEDRKRKKREQEVILNKK.NARPKLSFSL
T1F0Z7_HELRO/106-256                KEMEEKYIEEEVARRVEELVATRVAEELEKRKDEIDREVMRRVEEAKAILERQILENFEKQRQAEIEAQRLKE............EEEQRKRDELENIMKENNRKIEEAQRKLA.......EEQLKLVEDQRRILEERQRIEDIERKKSRMEQEIILNKK.NARPRLSFSL
#=GC seq_cons                       pEhEtKllEEEssRRlEEhVtcRVpEcLc.Rc-EIctEltRRVEEu+ctME+phhpElE+c+ctplptp+tKE............EEE+cc+cELEclhcENp++lEEAQRKhA.......EERhthlEcpp+hcEE+tRhc+ccccch+pEQplILsKp.puRPKLSFoL
//