# STOCKHOLM 1.0
#=GF ID S100PBPR
#=GF AC PF15427.7
#=GF DE S100P-binding protein
#=GF AU Coggill P;0000-0001-5731-1588
#=GF GA 27.0 26.4
#=GF NC 25.7 25.4
#=GF TC 38.6 26.4
#=GF SE Jackhmmer:Q96BU1
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 15632002
#=GF RT Expression of S100P and its novel binding partner S100PBPR in
#=GF RT early pancreatic cancer.
#=GF RA Dowen SE, Crnogorac-Jurcevic T, Gangeswaran R, Hansen M,
#=GF RA Eloranta JJ, Bhakta V, Brentnall TA, Luttges J, Kloppel G,
#=GF RA Lemoine NR;
#=GF RL Am J Pathol. 2005;166:81-92.
#=GF RN [2]
#=GF RM 16129886
#=GF RT Transition from non-motile behaviour to directed migration
#=GF RT during early PGC development in zebrafish.
#=GF RA Blaser H, Eisenbeiss S, Neumann M, Reichman-Fried M, Thisse B,
#=GF RA Thisse C, Raz E;
#=GF RL J Cell Sci. 2005;118:4027-4038.
#=GF RN [3]
#=GF RM 18089492
#=GF RT Usefulness of S100P in diagnosis of adenocarcinoma of pancreas
#=GF RT on fine-needle aspiration biopsy specimens.
#=GF RA Deng H, Shi J, Wilkerson M, Meschter S, Dupree W, Lin F;
#=GF RL Am J Clin Pathol. 2008;129:81-88.
#=GF DR INTERPRO; IPR026097;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC S100PBPR is a family of proteins found in eukaryotes, and
#=GF CC localised to cell nuclei where S100P is also present, and the
#=GF CC two proteins co-immunoprecipitate. S100P is a member of the S100
#=GF CC family of calcium-binding proteins and there have been several
#=GF CC recent reports of its over-expression in pancreatic ductal
#=GF CC adenocarcinoma. In situ hybridisation shows S100PBPR transcripts
#=GF CC to be found in islet cells but not duct cells of the healthy
#=GF CC pancreas. An interaction between S100P and S100PBPR may be
#=GF CC involved in early pancreatic cancer.
#=GF SQ 5
Q96BU1.1/22-402     -APFSWDSLDEDGLDDSLLELSEGEEDDGDVNYTEEEIDALLKEDDPSYEQSSG..E----.-DDGGHVEKGERGSQILLDTPREKNSSYSLGPVAETPDLFKLPQLSTSSGHGPA...HTKPLNRRS..VLEKNLIK.....VT-V.....APFNPTVCDALLDKDETDSSKDTEKLSSLGEEMREDGLSPNESKLCTESEGISPNNSAWNGPQLSS-SN........................NNFQQTVSDKNMPDSENPTSVFSRIS.DHSETPNMELSC..RNG.....GSHKSSCEMRSLVVSTSS..NKQ..dVLNKDSGKMKGHERRLGKVIPVLQTKTRTNVPT.FSQSNLEQQKQLYLRSVIAHIEDPEDTNQGISGELCALMDQV....HHMQHSKWQHPSDLTTRNYAR-RQKHLQRYSLTQWVDRNMRSHHRFQRL
D3ZSX9.1/21-382     NASFSWGSSDEDELDDSLLEFSDGEEDDGHFSFTEEEIEMLLKDDD--------..-----.---GGHNEYRARKSQILPHTPQE-NSLYSLGPAAETPGFLKLPQLSPSVGHGPT...PSKSLNRHF..VLEKNLIK.....VTVV.....APFNPTVCDPVLDKDKIDSSKETEKPASLQEQTREDDLHPNESKRCTEPEGVSPNNSAWDGPLLSSPSN........................NNIEQTASDKNIPESKKPTPVFSQIS.NHSEVPN----R..KNS.....GSHKSGCEVRIPVVSSSS..NRH...AFDKDSGEAKG-ERRLGKVIPVLQTRTR----M.FSQSDLEKQKDIYLSKVIAHIEDPGDSNQGALGELDALMDQV....-HMQNPDWQHPSDLTTRNYARFRQRPLQRYSLSQWVDRNKRSHHRFQRL
Q9D5K4.1/21-382     NASFPWGSLDEDELDDSLLEFSDGEEDDGHFSFTEEEIEMLLKDDD--------..-----.---GGHNEYRPRKSQILPDIPQE-NSLYSLGPAAETPGFLKLPQLSTSVGHGPT...PSKSLNRHF..VLEKNLIK.....VTVV.....APFNPTVCDPVLDKDKIDSSKETENPASLREQTREDDPQPNESKRCTEPEGVSPNTSAWDGPLLSSPSN........................NNIEQTASDKNIPESKKPTPVFSQIS.NHSEVPN----R..KNS.....GSHKSGCEVRIPVVSSSS..NRH...AFDKDSGEAKG-ERRLGKVIPVLQTRTR----M.FSQSELEKQKDIYLSKVIAHIEDPGDSNQGTLGELDALMDQV....-HMQHPDWQHPSDLTTRNYARFRQRPLQRYSLSQWVDRNKRSHHRFQRL
M7BJQ5.1/108-545    -------CFDDSEPDDSLLEPSDDEQGNSPFNYTEEECREMLADDCLGDDQNSP.gESALVtLDVWGQSEKEVSSNCSWASVPPE-GTETSFRTIDELVSNESLSQTGSSVNTGYFrilENETANSEVegCLNVDCLKsnqviCTLFdcdlqGPLNLSPTDA-DSVDQLKGDDGLEKTGEKASQVIRDDHLQNASKQSIEYDEISSNSLVVEESLVSKEQHrggmdnveklpseikessffydahTKFSTSSPDPACSQSKDKVENTAPVLlLHPKPSNVVLNQdpSNGlsgtfGSQKEDLSQESTSVEESSenLKLnsvVLDQNCGEATTCGKKLGKVIPVPQVEERPKQRIcISEAELEQKKYIYIQCVRAHVKNSMDPTPDALNELYALMDKVasreYRTQDRRWQHPSDLTMRKYPRFSKKPTQKCSLKQWVSRNLAHHRRFQD-
A0A3M0IRE3.1/99-164 ------RCFDDSELDDSLLELSGSEEESSSFDYTEEEIQEILADDSLEAEQQHLagESHLS.QSEGDKAESSG-------------------------------------------...---------..--------.....----.....---------------------------------------------------------------------........................--------------------------.------------..---.....------------------..---...---------------------------------.------------------------------------------....-------------------------------------------------
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