Summary: Accessory Sec secretory system ASP3
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Sec-ASP3 is family of bacterial proteins involved in the Sec secretory system. The family forms part of the accessory SecA2/SecY2 system specifically required to export GspB, a serine-rich repeat cell-wall glycoprotein adhesin encoded upstream in the same operon.
Yen YT, Seepersaud R, Bensing BA, Sullam PM;, J Bacteriol. 2011;193:3165-3174.: Asp2 and Asp3 interact directly with GspB, the export substrate of the Streptococcus gordonii accessory Sec System. PUBMED:21531800 EPMC:21531800
This tab holds annotation information from the InterPro database.
InterPro entry IPR022259
Asp3 is part of an accessory SecA2/SecY2 system, which is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus [PUBMED:18621893]. SecA2/SecY2 system specifically required to export SraP, a serine-rich repeat cell wall protein encoded upstream in the same operon [PUBMED:18621893]. In Streptococcus gordonii, it may also function in part as chaperones in the early phase of GspB (a serine-rich glycoprotein adhesin) transport [PUBMED:21531800].
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|Biological process||protein transport (GO:0015031)|
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Curation and family details
|Number in seed:||20|
|Number in full:||79|
|Average length of the domain:||122.40 aa|
|Average identity of full alignment:||28 %|
|Average coverage of the sequence by the domain:||48.84 %|
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build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||5|
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