Summary: Phosphoribosyl transferase
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Phosphoribosyl transferase Provide feedback
This PRTase family, with C terminal TRSP domain, are related to OPRTases  and are predicted to use Orotate as substrate. These genes are found in the biosynthetic operon associated with the Ter stress response operon and are predicted to be involved in the biosynthesis of a ribo- nucleoside involved in stress response .
Müller FH, Bandeiras TM, Urich T, Teixeira M, Gomes CM, Kletzin A , Mol Microbiol 2004;0:0-0.: Coupling of the Pathway of Sulfur Oxidation to Dioxygen Reduction: Characterization of a Novel Membrane-Bound Thiosulfate:Quinone Oxidoreductase 2 PUBMED:0 EPMC:0
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- the number of sequences which exhibit this architecture
a textual description of the architecture, e.g. Gla, EGF x 2, Trypsin.
This example describes an architecture with one
Gladomain, followed by two consecutive
EGFdomains, and finally a single
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This superfamily of phosphoribosyl-transferases (PRTases) and phosphoribosyl-pyrophosphate synthetase-like protein families is characterised by a core fold of three layers, a/b/a with a mixed beta-sheet of six strands. In one of the families consists of two domains of this fold.
The clan contains the following 6 members:Pribosyl_synth Pribosyltran PRTase_1 PRTase_2 PRTase_3 UPRTase
We make a range of alignments for each Pfam-A family:
- the curated alignment from which the HMM for the family is built
- the alignment generated by searching the sequence database using the HMM
- Representative Proteomes (RPs) at 15%, 35%, 55% and 75% co-membership thresholds
- alignment generated by searching the NCBI sequence database using the family HMM
- alignment generated by searching the metagenomics sequence database using the family HMM
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1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
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Curation and family details
This family is new in this Pfam release.
|Seed source:||Anantharaman V|
|Number in seed:||67|
|Number in full:||330|
|Average length of the domain:||196.20 aa|
|Average identity of full alignment:||43 %|
|Average coverage of the sequence by the domain:||44.89 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||1|
|Download:||download the raw HMM for this family|
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