Summary: ATP-grasp in the biosynthetic pathway with Ter operon
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ATP-grasp in the biosynthetic pathway with Ter operon Provide feedback
This ATP-grasp family is related to carbamoyl phosphate synthetase. These genes are found in the biosynthetic operon associated with the Ter stress response operon and are predicted to be involved in the biosynthesis of a ribo-nucleoside involved in stress response .
Anantharaman V, Iyer LM, Aravind L;, Mol Biosyst. 2012;8:3142-3165.: Ter-dependent stress response systems: novel pathways related to metal sensing, production of a nucleoside-like metabolite, and DNA-processing. PUBMED:23044854 EPMC:23044854
Internal database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR011226
This entry represents a family of bacterial proteins that contain an ATP-grasp domain. They are related to carbamoyl phosphate synthetases. Their genes are found in the biosynthetic operon associated with the Ter stress response operon and are predicted to be involved in the biosynthesis of a ribo-nucleoside involved in stress response [PUBMED:23044854].
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This example describes an architecture with one
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The ATP-grasp domain is found in a wide variety of carboxylate-amine/thiol ligases . It is composed of two subdomains, with ATP being bound in the cleft between the two.
The clan contains the following 22 members:ATP-grasp ATP-grasp_2 ATP-grasp_3 ATP-grasp_4 ATP-grasp_5 ATPgrasp_ST ATPgrasp_Ter ATPgrasp_TupA ATPgrasp_YheCD CP_ATPgrasp_1 CP_ATPgrasp_2 CPSase_L_D2 Dala_Dala_lig_C DUF1297 GARS_A GSH-S_ATP GSP_synth Ins134_P3_kin PPDK_N RimK Synapsin_C TTL
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Curation and family details
|Seed source:||Anantharaman V|
|Number in seed:||30|
|Number in full:||169|
|Average length of the domain:||330.80 aa|
|Average identity of full alignment:||32 %|
|Average coverage of the sequence by the domain:||93.18 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||5|
|Download:||download the raw HMM for this family|
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