# STOCKHOLM 1.0
#=GF ID   AvrPtoB_bdg
#=GF AC   PF16847.6
#=GF DE   Avirulence AvrPtoB, BAK1-binding domain
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   pdb_3tl8
#=GF GA   27.00 27.00;
#=GF TC   27.00 28.70;
#=GF NC   26.90 23.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   22169508
#=GF RT   Structural analysis of Pseudomonas syringae AvrPtoB bound to
#=GF RT   host BAK1 reveals two similar kinase-interacting domains in a
#=GF RT   type III Effector.
#=GF RA   Cheng W, Munkvold KR, Gao H, Mathieu J, Schwizer S, Wang S, Yan
#=GF RA   YB, Wang J, Martin GB, Chai J;
#=GF RL   Cell Host Microbe. 2011;10:616-626.
#=GF DR   INTERPRO; IPR031759;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   AvrPtoB_bdg is a binding region on a family of bacterial plant
#=GF CC   pathogenic proteins. Type III effector proteins are injected
#=GF CC   into plants by bacteria when they are under attack, eg
#=GF CC   Pseudomonas syringae when attacking tomato. AvrPtoB is one such
#=GF CC   effector that suppresses the plants' PAMP-triggered innate
#=GF CC   immunity.  PAMPs are pathogen/microbe-associated molecular
#=GF CC   patterns that are detected as non-self by a host.  AvrPtoB
#=GF CC   suppresses this response by binding to BAK1, a kinase that acts
#=GF CC   with several pattern recognition receptors to activate defence
#=GF CC   signalling. AvrPtoB_bdg is the region of AvrPtoB that binds to
#=GF CC   BAK1 thereby preventing its kinase activity after the perception
#=GF CC   of flagellin [1].
#=GF SQ   2
#=GS HPAB2_PSESM/266-356       AC Q8RSY1.1
#=GS HPAB2_PSESM/266-356       DR PDB; 3TL8 B; 267-353;
#=GS HPAB2_PSESM/266-356       DR PDB; 3TL8 F; 267-354;
#=GS HPAB2_PSESM/266-356       DR PDB; 3TL8 K; 267-354;
#=GS HPAB2_PSESM/266-356       DR PDB; 3TL8 L; 268-354;
#=GS A0A3D8JU15_9BURK/280-367  AC A0A3D8JU15.1
HPAB2_PSESM/266-356                  .......PIRVDRAAMRNRGNDEADAALRG.LVQQGVNLEHLRTALERHVMQRLPIPLDIGSALQNVGINPSIDLGESLVQHPLLNLNVALNRMLGLRP.....
#=GR HPAB2_PSESM/266-356       SS    .......XX---HHHHHHHHHHHHHHHHHH.HHCTT--HHHHHHHHHHHHHH-----HHHHHHHHCTT--S----SS-BS--HHHHHHHHHHHHCT-XX.....
A0A3D8JU15_9BURK/280-367             alqrqas-----------RANERPSGELLGrLADSGISTRRLHRALRSYLVDLLPLPPDILSALNRAGIETHIPEHIAIVSHPLFDLNRELNAQ-----asara
#=GC SS_cons                         .......XX---HHHHHHHHHHHHHHHHHH.HHCTT--HHHHHHHHHHHHHH-----HHHHHHHHCTT--S----SS-BS--HHHHHHHHHHHHCT-XX.....
#=GC seq_cons                        ..................RuN-cssutLhG.LsppGlshc+L+pALcpalhphLPlP.DIhSALppsGIpspIs.t.ulVpHPLhsLNhtLNt...........
//