Summary: Transcription factor Pcc1
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Transcription factor Pcc1 Provide feedback
Pcc1 is a transcription factor that functions in regulating genes involved in cell cycle progression and polarised growth .
Kisseleva-Romanova E, Lopreiato R, Baudin-Baillieu A, Rousselle JC, Ilan L, Hofmann K, Namane A, Mann C, Libri D; , EMBO J. 2006;25:3576-3585.: Yeast homolog of a cancer-testis antigen defines a new transcription complex. PUBMED:16874308 EPMC:16874308
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR015419Pcc1 is a proposed transcription factor involved in the expression of genes regulated by alpha-factor and galactose; component of the EKC/KEOPS protein complex with Kae1, Gon7, Bud32, and Cgi121; related to human cancer-testis antigens [PUBMED:16874308].
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Curation and family details
|Author:||Mistry J, Wood V|
|Number in seed:||57|
|Number in full:||386|
|Average length of the domain:||76.60 aa|
|Average identity of full alignment:||23 %|
|Average coverage of the sequence by the domain:||62.38 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||5|
|Download:||download the raw HMM for this family|
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For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Pcc1 domain has been found. There are 13 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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