Summary: Bacterial protein of unknown function (DUF882)
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Bacterial protein of unknown function (DUF882) Provide feedback
This family consists of a series of hypothetical bacterial proteins of unknown function.
Internal database links
|SCOOP:||Extensin-like_C Peptidase_M15_3 MRP-L46 Peptidase_M15_4 DUF4928|
|Similarity to PfamA using HHSearch:||Peptidase_M15_3|
External database links
- the number of sequences which exhibit this architecture
a textual description of the architecture, e.g. Gla, EGF x 2, Trypsin.
This example describes an architecture with one
Gladomain, followed by two consecutive
EGFdomains, and finally a single
- the UniProt description of the protein sequence
- the number of residues in the sequence
- the Pfam graphic itself.
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This clan is comprised of carboxypeptidases and the N-terminal domain from Sonic hedgehog proteins. The structure of the latter is similar to the peptidases, but the N-terminal domain of hedgehog has been demonstrate not to be involved in peptidase activity, but is more likely involved in signal transduction .
The clan contains the following 7 members:HH_signal Peptidase_M15 Peptidase_M15_2 Peptidase_M15_3 Peptidase_M15_4 Peptidase_M74 VanY
We make a range of alignments for each Pfam-A family:
- the curated alignment from which the HMM for the family is built
- the alignment generated by searching the sequence database using the HMM
- Representative Proteomes (RPs) at 15%, 35%, 55% and 75% co-membership thresholds
- alignment generated by searching the NCBI sequence database using the family HMM
- alignment generated by searching the metagenomics sequence database using the family HMM
You can see the alignments as HTML or in three different sequence viewers:
- Pfam viewer
- an HTML-based viewer that uses DAS to retrieve alignment fragments on request
1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
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Curation and family details
|Seed source:||Pfam-B_4115 (release 9.0)|
|Number in seed:||10|
|Number in full:||4589|
|Average length of the domain:||149.90 aa|
|Average identity of full alignment:||69 %|
|Average coverage of the sequence by the domain:||65.84 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||9|
|Download:||download the raw HMM for this family|
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