Summary: Serine peptidase of plant viral polyprotein, P1
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Serine peptidase of plant viral polyprotein, P1 Provide feedback
This family is the P1 protein of the Potyviridae polyproteins that is a serine peptidase at the N-terminus. The catalytic triad in Q65730 the ssRNA positive-strand Brome streak mosaic rymovirus, is His-311, Asp-322 and Ser-355.
Fellers JP, Seifers D, Ryba-White M, Martin TJ;, Arch Virol. 2009;154:1511-1515.: The complete genome sequence of Triticum mosaic virus, a new wheat-infecting virus of the High Plains. PUBMED:19649764 EPMC:19649764
Mbanzibwa DR, Tian Y, Mukasa SB, Valkonen JP;, J Virol. 2009;83:6934-6940.: Cassava brown streak virus (Potyviridae) encodes a putative Maf/HAM1 pyrophosphatase implicated in reduction of mutations and a P1 proteinase that suppresses RNA silencing but contains no HC-Pro. PUBMED:19386713 EPMC:19386713
Internal database links
|Similarity to PfamA using HHSearch:||Peptidase_S30|
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR025910This entry represents the serine peptidase at the N terminus of P1 protein of the Potyviridae polyproteins. The catalytic triad in P1 from the ssRNA positive-strand Brome streak mosaic rymovirus, is His-311, Asp-322 and Ser-355 [PUBMED:11226583, PUBMED:19649764, PUBMED:20565672, PUBMED:19386713].
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This clan contains a diverse set of peptidases with the trypsin fold.
The clan contains the following 24 members:DUF1986 DUF31 DUF316 Peptidase_C24 Peptidase_C3 Peptidase_C30 Peptidase_C37 Peptidase_C3G Peptidase_C4 Peptidase_C62 Peptidase_S29 Peptidase_S3 Peptidase_S30 Peptidase_S31 Peptidase_S32 Peptidase_S39 Peptidase_S46 Peptidase_S55 Peptidase_S6 Peptidase_S7 Peptidase_S76 Pico_P2A Trypsin Trypsin_2
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Curation and family details
|Author:||Rawlings N, Coggill P|
|Number in seed:||6|
|Number in full:||57|
|Average length of the domain:||123.60 aa|
|Average identity of full alignment:||34 %|
|Average coverage of the sequence by the domain:||5.04 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||1|
|Download:||download the raw HMM for this family|
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