Summary: Phage major coat protein, Gp8
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Class I phage major coat protein Gp8 or B. The coat protein is largely alpha-helix with a slight curve .
Marvin DA, Hale RD, Nave C, Helmer-Citterich M; , J Mol Biol 1994;235:260-286.: Molecular models and structural comparisons of native and mutant class I filamentous bacteriophages Ff (fd, f1, M13), If1 and IKe. PUBMED:8289247 EPMC:8289247
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This tab holds annotation information from the InterPro database.
InterPro entry IPR008020
This entry represents the class I phage major coat protein Gp8 or B. The coat protein is largely alpha-helix with a slight curve [PUBMED:8289247].
The major coat protein in the capsid of filamentous bacteriophage forms a helical assembly of about 7000 identical protomers, with each protomer comprised of 46 amino acids, after the cleavage of the signal peptide. Each protomer forms a slightly curved helix that combines to form a tubular structure that encapsulates the viral DNA [PUBMED:10666593].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Cellular component||viral capsid (GO:0019028)|
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Curation and family details
|Seed source:||Pfam-B_31655 (release 7.8)|
|Number in seed:||7|
|Number in full:||4|
|Average length of the domain:||53.50 aa|
|Average identity of full alignment:||33 %|
|Average coverage of the sequence by the domain:||70.16 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||9|
|Download:||download the raw HMM for this family|
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For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Phage_Coat_Gp8 domain has been found. There are 48 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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