Summary: Phage Head-Tail Attachment
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The phage head-tail attachment protein is required for the joining of phage heads and tails at the last step of morphogenesis .
Maxwell KL, Yee AA, Arrowsmith CH, Gold M, Davidson AR; , J Mol Biol 2002;318:1395-1404.: The solution structure of the bacteriophage lambda head-tail joining protein, gpFII. PUBMED:12083526 EPMC:12083526
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR008018
The phage head-tail attachment protein is required for the joining of phage heads and tails at the last step of morphogenesis [PUBMED:12083526]. FII is incorporated into the base vertex of DNA-filled heads to facilitate head-tail joining and may determine the specificity of tail attachment. There are 5-6 copies of protein FII per mature phage.
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Cellular component||viral capsid (GO:0019028)|
|Biological process||virion assembly (GO:0019068)|
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This superfamily consists of a variety of bacteriophage protein families. Structurally members of this family contain a beta barrel.
The clan contains the following 8 members:DUF2001 Gifsy-2 Minor_tail_Z Phage-tail_1 Phage-tail_2 Phage-tail_3 Phage_attach Phage_GPD
We make a range of alignments for each Pfam-A family:
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Curation and family details
|Seed source:||Pfam-B_59968 (release 7.8)|
|Number in seed:||3|
|Number in full:||3148|
|Average length of the domain:||109.10 aa|
|Average identity of full alignment:||78 %|
|Average coverage of the sequence by the domain:||99.05 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||7|
|Download:||download the raw HMM for this family|
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For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Phage_attach domain has been found. There are 2 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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