Summary: Prokaryotic RING finger family 4
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Prokaryotic RING finger family 4 Provide feedback
RING finger family domain found sporadically in bacteria. The finger is fused to an N-terminal alpha-helical domain, ROT/Trove-like repeats and a C-terminal TerD domain . The architecture suggests a possible role in an RNA-processing complex .
Burroughs AM, Iyer LM, Aravind L;, Mol Biosyst. 2011;7:2261-2277.: Functional diversification of the RING finger and other binuclear treble clef domains in prokaryotes and the early evolution of the ubiquitin system. PUBMED:21547297 EPMC:21547297
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- the number of sequences which exhibit this architecture
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This example describes an architecture with one
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This clan includes the Ring zinc finger domains as well as the U-box domain that appears to have lost the zinc coordinating cysteine residues .
The clan contains the following 38 members:Baculo_IE-1 Baculo_RING DUF1644 FANCL_C IBR Prok-RING_1 Prok-RING_2 Prok-RING_4 RINGv Rtf2 U-box UPF1_Zn_bind zf-ANAPC11 zf-C3H2C3 zf-C3HC4 zf-C3HC4_2 zf-C3HC4_3 zf-C3HC4_4 zf-C3HC4_5 zf-MIZ zf-NOSIP zf-Nse zf-P11 zf-rbx1 zf-RING-like zf-RING_10 zf-RING_11 zf-RING_2 zf-RING_4 zf-RING_5 zf-RING_6 zf-RING_7 zf-RING_9 zf-RING_UBOX zf-UBP zf-UDP zinc_ribbon_16 Zn_ribbon_17
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Curation and family details
|Author:||Burroughs AM, Iyer LM, Aravind L|
|Number in seed:||10|
|Number in full:||71|
|Average length of the domain:||54.60 aa|
|Average identity of full alignment:||38 %|
|Average coverage of the sequence by the domain:||7.21 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||2|
|Download:||download the raw HMM for this family|
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