Summary: Lipoprotein Rz1 precursor
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Lipoprotein Rz1 precursor Provide feedback
This family consists of several bacteria and phage lipoprotein Rz1 precursors. Rz1 is a proline-rich lipoprotein from bacteriophage lambda which is known to have fusogenic properties. Rz1-induced liposome fusion is thought to be mediated primarily by the generation of local perturbation in the bilayer lipid membrane and to a lesser extent by electrostatic forces . This family Rz1 and the Rz protein Rz (PF03245) represent a unique example of two genes located in different reading frames in the same nucleotide sequence, which encode different proteins that are both required in the same physiological pathway .
Bryl K, Kedzierska S, Laskowska M, Taylor A; , Eur J Biochem 2000;267:794-799.: Membrane fusion by proline-rich Rz1 lipoprotein, the bacteriophage lambda Rz1 gene product. PUBMED:10651816 EPMC:10651816
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR010346
This family consists of several bacteria and phage lipoprotein Rz1 precursors. Rz1 is a proline-rich lipoprotein from bacteriophage lambda, which is known to have fusogenic properties. Rz1-induced liposome fusion is thought to be mediated primarily by the generation of local perturbation in the bilayer lipid membrane and to a lesser extent by electrostatic forces [PUBMED:10651816].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Cellular component||outer membrane (GO:0019867)|
|Biological process||viral envelope fusion with host membrane (GO:0019064)|
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Curation and family details
|Seed source:||Pfam-B_8925 (release 9.0)|
|Number in seed:||7|
|Number in full:||97|
|Average length of the domain:||40.80 aa|
|Average identity of full alignment:||57 %|
|Average coverage of the sequence by the domain:||61.59 %|
|HMM build commands:||
build method: hmmbuild --amino -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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