Summary: SbmA/BacA-like family
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The Rhizobium meliloti bacA gene encodes a function that is essential for bacterial differentiation into bacteroids within plant cells in the symbiosis between R. meliloti and alfalfa. An Escherichia coli homolog of BacA, SbmA, is implicated in the uptake of microcins and bleomycin. This family is likely to be a subfamily of the ABC transporter family.
Ichige A, Walker GC; , J Bacteriol 1997;179:209-216.: Genetic analysis of the Rhizobium meliloti bacA gene: functional interchangeability with the Escherichia coli sbmA gene and phenotypes of mutants. PUBMED:8982000 EPMC:8982000
Internal database links
|Similarity to PfamA using HHSearch:||ABC_membrane_2|
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR009248
The Rhizobium meliloti (Sinorhizobium meliloti) bacA gene encodes a function that is essential for bacterial differentiation into bacteroids within plant cells in the symbiosis between R. meliloti and alfalfa. An Escherichia coli homologue of BacA, SbmA, is implicated in the uptake of microcins and bleomycin. This family is likely to be a subfamily of the ABC transporter family.
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Cellular component||Gram-negative-bacterium-type cell wall (GO:0009276)|
|integral to membrane (GO:0016021)|
|Molecular function||transporter activity (GO:0005215)|
|Biological process||transport (GO:0006810)|
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This clan includes families that are the membrane components of ABC transporter complexes. In general these regions are composed of six transmembrane helices .
The clan contains the following 4 members:ABC_membrane ABC_membrane_2 ABC_membrane_3 SbmA_BacA
We make a range of alignments for each Pfam-A family:
- the curated alignment from which the HMM for the family is built
- the alignment generated by searching the sequence database using the HMM
- Representative Proteomes (RPs) at 15%, 35%, 55% and 75% co-membership thresholds
- alignment generated by searching the NCBI sequence database using the family HMM
- alignment generated by searching the metagenomics sequence database using the family HMM
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Curation and family details
|Seed source:||Pfam-B_8139 (release 9.0)|
|Number in seed:||10|
|Number in full:||817|
|Average length of the domain:||298.70 aa|
|Average identity of full alignment:||62 %|
|Average coverage of the sequence by the domain:||77.94 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||7|
|Download:||download the raw HMM for this family|
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