Summary: Sulfite exporter TauE/SafE
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This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane  during taurine metabolism as an exporter of sulfoacetate . This family used to be known as DUF81.
Weinitschke S, Denger K, Cook AM, Smits TH; , Microbiology. 2007;153:3055-3060.: The DUF81 protein TauE in Cupriavidus necator H16, a sulfite exporter in the metabolism of C2 sulfonates. PUBMED:17768248 EPMC:17768248
Krejcik Z, Denger K, Weinitschke S, Hollemeyer K, Paces V, Cook AM, Smits TH; , Arch Microbiol. 2008;190:159-168.: Sulfoacetate released during the assimilation of taurine-nitrogen by Neptuniibacter caesariensis: purification of sulfoacetaldehyde dehydrogenase. PUBMED:18506422 EPMC:18506422
This tab holds annotation information from the InterPro database.
InterPro entry IPR002781
This is a family of integral membrane proteins containing transmembrane helices. This family used to be known as DUF81.
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Cellular component||integral component of membrane (GO:0016021)|
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This clan includes a diverse range of transporter families .
The clan contains the following 17 members:BacA Cad Colicin_V DsbD DsbD_2 DUF475 HupE_UreJ HupE_UreJ_2 LysE MarC Mntp NicO OFeT_1 SfLAP TauE TerC UPF0016
We make a range of alignments for each Pfam-A family:
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Curation and family details
|Seed source:||Enright A & Pfam-B_3578 (Release 7.5)|
|Author:||Enright A, Ouzounis C, Bateman A|
|Number in seed:||654|
|Number in full:||5559|
|Average length of the domain:||226.30 aa|
|Average identity of full alignment:||17 %|
|Average coverage of the sequence by the domain:||86.77 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||16|
|Download:||download the raw HMM for this family|
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