Summary: TraY domain
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This family consists of several enterobacterial TraY proteins. TraY is involved in bacterial conjugation where it is required for efficient nick formation in the F plasmid . These proteins have a ribbon-helix-helix fold and are likely to be DNA-binding proteins.
Chu C, Chiu CH, Chu CH, Ou JT; , J Bacteriol 2002;184:2857-2862.: Nucleotide and amino acid sequences of oriT-traM-traJ-traY-traA-traL regions and mobilization of virulence plasmids of Salmonella enterica serovars enteritidis, gallinarum-pullorum, and typhimurium. PUBMED:12003924 EPMC:12003924
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR008876This family consists of several enterobacterial TraY proteins. TraY is involved in bacterial conjugation where it is required for efficient nick formation in the F plasmid [PUBMED:12003924].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Molecular function||DNA binding (GO:0003677)|
|Biological process||conjugation (GO:0000746)|
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This superfamily contains the MetJ and Arc repressors that feature a ribbon-helix-helix DNA-binding motif with the beta-ribbon located in and recognising the major groove of operator DNA .
The clan contains the following 21 members:Arc CcdA DUF1662 DUF1778 DUF2191 DUF2610 DUF3423 DUF3924 HicB MetJ Omega_Repress ParD ParG PSK_trans_fac RelB RepB-RCR_reg RHH_1 RHH_2 RHH_3 RHH_4 TraY
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Curation and family details
|Seed source:||Pfam-B_8963 (release 8.0)|
|Author:||Moxon SJ, Bateman A|
|Number in seed:||28|
|Number in full:||257|
|Average length of the domain:||48.00 aa|
|Average identity of full alignment:||45 %|
|Average coverage of the sequence by the domain:||68.00 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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