Summary: Ubiquinol-cytochrome C reductase complex 14kD subunit
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Ubiquinol-cytochrome C reductase complex 14kD subunit Provide feedback
The ubiquinol-cytochrome C reductase complex (cytochrome bc1 complex) is a respiratory multienzyme complex . This Pfam family represents the 14kD (or VI) subunit of the complex which is not directly involved in electron transfer, but has a role in assembly of the complex .
Iwata S, Lee JW, Okada K, Lee JK, Iwata M, Rasmussen B, Link TA, Ramaswamy S, Jap BK; , Science 1998;281:64-71.: Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex [see comments] PUBMED:9651245 EPMC:9651245
Braun HP, Schmitz UK; , Plant Physiol 1995;107:1217-1223.: Molecular features and mitochondrial import pathway of the 14-kilodalton subunit of cytochrome c reductase from potato. PUBMED:7770525 EPMC:7770525
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR003197Cytochrome b-c1 complex subunit 7 (QCR7, also known as UQCRB) is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. QCR7 is involved in redox-linked proton pumping [PUBMED:2170131, PUBMED:6319130, PUBMED:11556808].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Cellular component||mitochondrial respiratory chain complex III (GO:0005750)|
|Biological process||mitochondrial electron transport, ubiquinol to cytochrome c (GO:0006122)|
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Curation and family details
|Seed source:||Pfam-B_4192 (release 5.2)|
|Author:||Mian N, Bateman A|
|Number in seed:||116|
|Number in full:||696|
|Average length of the domain:||97.40 aa|
|Average identity of full alignment:||38 %|
|Average coverage of the sequence by the domain:||73.36 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||12|
|Download:||download the raw HMM for this family|
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For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the UCR_14kD domain has been found. There are 60 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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