Summary: UTRA domain
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UTRA domain Provide feedback
The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to PF04345 . It is believed to modulate activity of bacterial transcription factors in response to binding small molecules .
Aravind L, Anantharaman V; , FEMS Microbiol Lett 2003;222:17-23.: HutC/FarR-like bacterial transcription factors of the GntR family contain a small molecule-binding domain of the chorismate lyase fold. PUBMED:12757941 EPMC:12757941
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR011663The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to INTERPRO [PUBMED:12757941]. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules [PUBMED:12757941].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Molecular function||DNA binding (GO:0003677)|
|Biological process||regulation of transcription, DNA-dependent (GO:0006355)|
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Curation and family details
|Author:||Anantharaman V, Aravind L, Studholme DJ|
|Number in seed:||168|
|Number in full:||12427|
|Average length of the domain:||138.40 aa|
|Average identity of full alignment:||19 %|
|Average coverage of the sequence by the domain:||57.50 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||8|
|Download:||download the raw HMM for this family|
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For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the UTRA domain has been found. There are 54 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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