Summary: Lipopolysaccharide core biosynthesis protein (WaaY)
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Lipopolysaccharide core biosynthesis protein (WaaY) Provide feedback
This family consists of several bacterial lipopolysaccharide core biosynthesis proteins (WaaY or RfaY). The waaY, waaQ, and waaP genes are located in the central operon of the waa (formerly rfa) locus on the chromosome of Escherichia coli. This locus contains genes whose products are involved in the assembly of the core region of the lipopolysaccharide molecule. WaaY is the enzyme that phosphorylates HepII in this system .
Yethon JA, Heinrichs DE, Monteiro MA, Perry MB, Whitfield C; , J Biol Chem 1998;273:26310-26316.: Involvement of waaY, waaQ, and waaP in the modification of Escherichia coli lipopolysaccharide and their role in the formation of a stable outer membrane. PUBMED:9756860 EPMC:9756860
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR009330
This family consists of several bacterial lipopolysaccharide core biosynthesis proteins (WaaY or RfaY). The waaY, waaQ, and waaP genes are located in the central operon of the waa (formerly rfa) locus on the chromosome of Escherichia coli. This locus contains genes whose products are involved in the assembly of the core region of the lipopolysaccharide molecule. WaaY is the enzyme that phosphorylates HepII in this system [PUBMED:9756860].
|Biological process||lipopolysaccharide core region biosynthetic process (GO:0009244)|
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This superfamily includes the Serine/Threonine- and Tyrosine- protein kinases as well as related kinases that act on non-protein substrates.
The clan contains the following 19 members:ABC1 APH APH_6_hur Choline_kinase DUF1679 DUF2252 EcKinase Fructosamin_kin Kdo Kinase-like PIP49_C Pkinase Pkinase_Tyr Pox_ser-thr_kin RIO1 Seadorna_VP7 UL97 WaaY YrbL-PhoP_reg
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Curation and family details
|Seed source:||Pfam-B_10767 (release 9.0)|
|Number in seed:||4|
|Number in full:||512|
|Average length of the domain:||198.00 aa|
|Average identity of full alignment:||52 %|
|Average coverage of the sequence by the domain:||81.44 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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