Summary: Yip1 domain
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The Yip1 integral membrane domain contains four transmembrane alpha helices. The domain is characterised by the motifs DLYGP and GY. The Yip1 protein is a golgi protein involved in vesicular transport that interacts with GTPases .
Yang X, Matern HT, Gallwitz D; , EMBO J 1998;17:4954-4963.: Specific binding to a novel and essential Golgi membrane protein (Yip1p) functionally links the transport GTPases Ypt1p and Ypt31p. PUBMED:9724632 EPMC:9724632
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR006977
This entry contains proteins belonging to the Yip1 family and represents the Yip1 domain. The Yip1 integral membrane domain contains four transmembrane alpha helices. The domain is characterised by the motifs DLYGP and GY. The Yip1 protein is a golgi protein involved in vesicular transport that interacts with GTPases [PUBMED:9724632].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Cellular component||membrane (GO:0016020)|
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Yip1 and YIF1 are members of an integral membrane complex which bind to Ras-like GTPases and are required for membrane fusion of ER derived vesicles with the Golgi .
The clan contains the following 6 members:DUF1048 DUF1129 DUF1282 DUF1700 YIF1 Yip1
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Curation and family details
|Seed source:||Pfam-B_5598 (release 7.6)|
|Author:||Finn RD, Bateman A|
|Number in seed:||208|
|Number in full:||1661|
|Average length of the domain:||174.80 aa|
|Average identity of full alignment:||14 %|
|Average coverage of the sequence by the domain:||66.95 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||12|
|Download:||download the raw HMM for this family|
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