Summary: Yqey-like protein
This is the Wikipedia entry entitled "Yqey protein domain". More...
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Yqey protein domain Edit Wikipedia article
structure of cytosolic protein of unknown function yqey from bacillus subtilis
In molecular biology, the protein domain Yqey is a putative protein of unknown function. It is thought to possibly have a role in protein synthesis, by aiding a molecule named, tRNA, to translate of mRNA into protein. This hypothetical explanation is further supported by structural homology to other tRNA binding proteins.
The Yqey domain has been found to be involved in the recognition of transfer RNA charged with Glutamine (tRNAGln) recognition. It has also been demonstrated that Yqey plays the role of an affinity enhancer of GlnRS for tRNAGln acting only in cis. However, the presence of Yqey in free state in organisms lacking GlnRS, suggests that this domain may exert additional cellular functions.  The function of the Yqey protein domain still remains to be full elucidated, however, sequence homology, may provide a clue.
Yqey-like protein Provide feedback
The function of this domain found in the YqeY protein is uncertain.
Internal database links
|SCOOP:||EnY2 DUF2962 DUF3349 DUF3580 MOZART1 TTRAP EndoU_bacteria FAM180 Tai4|
|Similarity to PfamA using HHSearch:||GatB_Yqey|
External database links
- the number of sequences which exhibit this architecture
a textual description of the architecture, e.g. Gla, EGF x 2, Trypsin.
This example describes an architecture with one
Gladomain, followed by two consecutive
EGFdomains, and finally a single
- the UniProt description of the protein sequence
- the number of residues in the sequence
- the Pfam graphic itself.
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We make a range of alignments for each Pfam-A family:
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1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
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Curation and family details
|Seed source:||Bateman A|
|Number in seed:||42|
|Number in full:||8513|
|Average length of the domain:||143.70 aa|
|Average identity of full alignment:||39 %|
|Average coverage of the sequence by the domain:||95.50 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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The tree shows the occurrence of this domain across different species. More...
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For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the YqeY domain has been found. There are 1 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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