Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.

Browse Pfam families

New Top twenty Numbers A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
ID Accession Type Number of sequences Average length Average %id Average coverage Has 3D Change status Description
Seed Full
E1-E2_ATPase PF00122 Family 79 39593 185.40 22 21.20 Changed E1-E2 ATPase
E1-N PF14463 Family 2 1 151.00 100 33.19 Changed E1 N-terminal domain
E1_4HB PF16191 Domain 276 1162 69.70 39 6.61 Changed Ubiquitin-activating enzyme E1 four-helix bundle
E1_DerP2_DerF2 PF02221 Domain 91 1950 126.50 19 60.44 Changed ML domain
E1_dh PF00676 Family 14 11474 297.00 26 49.16 Changed Dehydrogenase E1 component
E1_FCCH PF16190 Domain 173 1177 71.20 47 6.73 Changed Ubiquitin-activating enzyme E1 FCCH domain
E1_UFD PF09358 Domain 180 1157 90.80 37 8.89 Changed Ubiquitin fold domain
E2 PF08199 Family 1 1 37.00 100 100.00 Changed Bacteriophage E2-like protein
E2F_CC-MB PF16421 Domain 165 1161 97.90 39 25.29 Changed E2F transcription factor CC-MB domain
E2F_TDP PF02319 Domain 205 2945 71.10 40 19.35 Changed E2F/DP family winged-helix DNA-binding domain
E2R135 PF11570 Coiled-coil 1 5 87.40 35 29.39 Changed Coiled-coil receptor-binding R-domain of colicin E2
E2_bind PF08825 Domain 146 713 83.80 35 18.48 Changed E2 binding domain
E3_binding PF02817 Family 992 9586 35.70 40 7.91 Changed e3 binding domain
E3_UbLigase_EDD PF11547 Family 10 257 51.80 80 1.88 Changed E3 ubiquitin ligase EDD
E3_UbLigase_R4 PF13764 Family 32 455 555.30 30 19.57 Changed E3 ubiquitin-protein ligase UBR4
E3_UFM1_ligase PF09743 Family 67 464 246.00 33 35.51 Changed E3 UFM1-protein ligase 1
E6 PF00518 Family 12 35 109.30 28 70.09 Changed Early Protein (E6)
E7 PF00527 Family 9 30 86.60 26 86.14 Changed E7 protein, Early protein
E7R PF17467 Family 2 2 60.00 88 53.10 New Viral Protein E7
EABR PF12180 Domain 12 198 33.80 52 8.06 Changed TSG101 and ALIX binding domain of CEP55
Ead_Ea22 PF13935 Family 30 16 133.10 22 73.96 Changed Ead/Ea22-like protein
EAF PF09816 Domain 107 798 101.40 29 28.52 Changed RNA polymerase II transcription elongation factor
Eaf7 PF07904 Family 61 615 107.00 25 39.47 Changed Chromatin modification-related protein EAF7
EAGR_box PF16713 Domain 22 32 33.80 43 9.51 Changed Enriched in aromatic and glycine Residues box
EAL PF00563 Domain 72 22957 227.00 29 33.94 Changed EAL domain
EamA PF00892 Family 97 67243 135.30 15 77.12 Changed EamA-like transporter family
EAP30 PF04157 Family 236 1580 217.50 25 58.25 Changed EAP30/Vps36 family
Eapp_C PF10238 Family 66 370 123.50 36 51.85 Changed E2F-associated phosphoprotein
EAR PF07897 Family 30 228 38.10 51 10.93 Changed Ethylene-responsive binding factor-associated repression
EAV_GP5 PF15981 Family 1 1 80.00 100 31.37 Changed Envelope glycoprotein GP 5 of equine arteritis virus
EAV_GS PF01309 Family 1 1 196.00 100 86.34 Changed Equine arteritis virus small envelope glycoprotein
EB PF01683 Family 226 3966 56.30 25 22.77 Changed EB module
EB1 PF03271 Family 167 1248 41.70 52 13.72 Changed EB1-like C-terminal motif
EB1_binding PF05937 Family 6 93 168.60 78 6.29 Changed EB-1 Binding Domain
EBA-175_VI PF11556 Family 11 77 80.20 49 6.13 Changed Erythrocyte binding antigen 175
Ebola_NP PF05505 Family 2 4 561.00 38 90.81 Changed Ebola nucleoprotein
EBP PF05241 Family 175 1029 176.00 28 69.22 Changed Emopamil binding protein
Ebp2 PF05890 Family 137 861 248.00 32 74.50 Changed Eukaryotic rRNA processing protein EBP2
EBP50_C PF09007 Domain 35 275 94.30 38 37.53 Changed EBP50, C-terminal
EBV-NA1 PF02905 Domain 2 2 146.00 89 22.78 Changed Epstein Barr virus nuclear antigen-1, DNA-binding domain
EBV-NA3 PF05009 Family 3 6 257.70 38 26.59 Changed Epstein-Barr virus nuclear antigen 3 (EBNA-3)
EB_dh PF09459 Domain 26 357 238.10 18 65.08 Changed Ethylbenzene dehydrogenase
EccE PF11203 Family 55 337 101.50 27 22.82 Changed Putative type VII ESX secretion system translocon, EccE
ECF-ribofla_trS PF07155 Family 47 1498 161.10 20 80.62 Changed ECF-type riboflavin transporter, S component
ECF_trnsprt PF12822 Family 57 2632 168.70 18 80.83 Changed ECF transporter, substrate-specific component
ECH_1 PF00378 Domain 9 33223 232.20 24 68.61 Changed Enoyl-CoA hydratase/isomerase
ECH_2 PF16113 Domain 292 3156 296.20 32 78.69 Changed Enoyl-CoA hydratase/isomerase
EcKinase PF02958 Family 51 2150 240.70 18 61.82 Changed Ecdysteroid kinase
Ecl1 PF12855 Family 22 391 41.00 37 18.98 Changed Life-span regulatory factor
Eclosion PF04736 Family 10 70 59.60 50 60.19 Changed Eclosion hormone
ECM1 PF05782 Family 12 87 339.20 42 91.68 Changed Extracellular matrix protein 1 (ECM1)
ECM11 PF15463 Family 68 235 134.00 29 27.31 Changed Extracellular mutant protein 11
Ecm29 PF13001 Family 123 768 406.20 23 27.71 Changed Proteasome stabiliser
Ecm33 PF12454 Family 17 133 40.10 43 10.02 Changed GPI-anchored cell wall organization protein
Eco57I PF07669 Domain 17 1018 109.80 23 12.46 Changed Eco57I restriction-modification methylase
EcoEI_R_C PF08463 Family 228 1011 156.50 19 17.74 Changed EcoEI R protein C-terminal
EcoR124_C PF12008 Domain 176 706 263.00 21 28.71 Changed Type I restriction and modification enzyme - subunit R C terminal
EcoRI PF02963 Domain 7 21 213.70 48 86.91 Changed Restriction endonuclease EcoRI
EcoRII-C PF09019 Domain 9 107 160.20 37 44.60 Changed EcoRII C terminal
EcoRII-N PF09217 Domain 7 49 128.40 32 37.23 Changed Restriction endonuclease EcoRII, N-terminal
EcoRI_methylase PF13651 Family 23 184 258.60 37 89.96 Changed Adenine-specific methyltransferase EcoRI
Ecotin PF03974 Family 53 198 122.30 38 71.54 Changed Ecotin
ECR1_N PF14382 Domain 249 1264 38.60 35 14.30 Changed Exosome complex exonuclease RRP4 N-terminal region
EcsB PF05975 Family 66 575 340.40 22 94.95 Changed Bacterial ABC transporter protein EcsB
EcsC PF12787 Family 86 1003 227.70 19 85.03 Changed EcsC protein family
ECSCR PF15820 Family 2 56 95.20 66 41.85 Changed Endothelial cell-specific chemotaxis regulator
ECSIT PF06239 Family 19 213 194.10 36 50.48 Changed Evolutionarily conserved signalling intermediate in Toll pathway
ECSIT_C PF14784 Domain 42 178 119.00 34 32.23 Changed C-terminal domain of the ECSIT protein
Ectatomin PF06457 Domain 2 0 0.00 0 0.00 Changed Ectatomin
ecTbetaR2 PF08917 Domain 20 143 108.80 51 20.64 Changed Transforming growth factor beta receptor 2 ectodomain
Ectoine_synth PF06339 Family 33 631 125.50 48 95.16 Changed Ectoine synthase
Edc3_linker PF16598 Family 7 113 89.90 76 18.58 Changed Linker region of enhancer of mRNA-decapping protein 3
EDR1 PF14381 Family 75 1078 190.40 30 24.13 Changed Ethylene-responsive protein kinase Le-CTR1
EELM2 PF15863 Domain 8 71 158.00 47 30.61 Changed Extended EGL-27 and MTA1 homology domain
EF-1_beta_acid PF10587 Domain 77 924 27.50 63 9.69 Changed Eukaryotic elongation factor 1 beta central acidic region
EF-G-binding_N PF07299 Domain 31 183 82.80 29 38.99 Changed Elongation factor G-binding protein, N-terminal
EF-hand_1 PF00036 Domain 570 6076 28.60 30 9.64 Changed EF hand
EF-hand_10 PF14788 Domain 9 123 49.80 48 7.00 Changed EF hand
EF-hand_11 PF08976 Domain 2 232 89.40 31 17.73 Changed EF-hand domain
EF-hand_2 PF09068 Domain 66 1069 119.80 38 9.82 Changed EF hand
EF-hand_3 PF09069 Domain 23 1080 90.30 43 7.49 Changed EF-hand
EF-hand_4 PF12763 Family 13 5442 95.10 30 16.59 Changed Cytoskeletal-regulatory complex EF hand
EF-hand_5 PF13202 Domain 103 15079 23.40 29 8.20 Changed EF hand
EF-hand_6 PF13405 Domain 600 4007 31.90 31 10.46 Changed EF-hand domain
EF-hand_7 PF13499 Domain 97 37814 68.80 26 21.07 Changed EF-hand domain pair
EF-hand_8 PF13833 Domain 38 12274 49.20 22 12.71 Changed EF-hand domain pair
EF-hand_9 PF14658 Domain 7 120 65.60 35 12.38 Changed EF-hand domain
EF-hand_like PF09279 Domain 26 2045 85.70 29 8.39 Changed Phosphoinositide-specific phospholipase C, efhand-like
EF1G PF00647 Domain 106 1028 103.90 47 25.36 Changed Elongation factor 1 gamma, conserved domain
EF1_GNE PF00736 Domain 187 1601 84.70 49 34.53 Changed EF-1 guanine nucleotide exchange domain
efb-c PF12199 Domain 2 3 66.30 42 52.09 Changed Extracellular fibrinogen binding protein C terminal
EFF-AFF PF14884 Family 4 191 384.70 28 89.02 Changed Type I membrane glycoproteins cell-cell fusogen
Effector_1 PF04518 Family 5 20 282.40 30 61.20 Changed Effector from type III secretion system
Efg1 PF10153 Family 130 522 112.80 35 37.79 Changed rRNA-processing protein Efg1
EFG_C PF00679 Domain 124 20960 87.60 28 12.77 Changed Elongation factor G C-terminus
EFG_II PF14492 Domain 84 11552 73.70 38 9.95 Changed Elongation Factor G, domain II
EFG_IV PF03764 Domain 67 10580 118.20 32 16.37 Changed Elongation factor G, domain IV
EFhand_Ca_insen PF08726 Domain 18 1230 68.00 42 5.97 Changed Ca2+ insensitive EF hand
EFP PF01132 Domain 861 4864 53.80 32 28.36 Changed Elongation factor P (EF-P) OB domain
EFP_N PF08207 Domain 177 5085 57.50 34 30.56 Changed Elongation factor P (EF-P) KOW-like domain
efThoc1 PF11957 Family 49 862 409.20 25 68.06 Changed THO complex subunit 1 transcription elongation factor
EFTUD2 PF16004 Family 153 768 110.50 46 11.68 Changed 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
EF_assoc_1 PF08355 Family 99 924 72.90 42 11.21 Changed EF hand associated
EF_assoc_2 PF08356 Family 80 992 86.30 45 13.57 Changed EF hand associated
EF_TS PF00889 Family 103 5120 191.30 30 68.71 Changed Elongation factor TS
EGF PF00008 Domain 67 41563 31.80 39 9.15 Changed EGF-like domain
EGF_2 PF07974 Domain 50 3981 30.70 41 4.14 Changed EGF-like domain
EGF_3 PF12947 Domain 136 3734 36.30 40 4.19 Changed EGF domain
EGF_alliinase PF04863 Domain 20 122 54.80 57 12.35 Changed Alliinase EGF-like domain
EGF_CA PF07645 Domain 18 43415 41.80 35 11.79 Changed Calcium-binding EGF domain
EGF_MSP1_1 PF12946 Domain 9 48 37.10 37 2.62 Changed MSP1 EGF domain 1
Egg_lysin PF01303 Domain 24 4 112.80 43 74.18 Changed Egg lysin (Sperm-lysin)
EGL-1 PF11430 Family 10 14 19.60 65 18.99 Changed Programmed cell death activator EGL-1
Ehbp PF10622 Family 11 24 78.80 49 88.53 Changed Energy-converting hydrogenase B subunit P (EhbP)
EHD_N PF16880 Family 86 969 32.60 49 5.89 Changed N-terminal EH-domain containing protein
EHN PF06441 Family 600 2659 108.20 35 26.20 Changed Epoxide hydrolase N terminus
Ehrlichia_rpt PF09528 Repeat 4 6 35.70 70 25.75 Changed Ehrlichia tandem repeat (Ehrlichia_rpt)
EH_Signature PF15611 Domain 25 122 368.00 15 76.88 Changed EH_Signature domain
EI24 PF07264 Family 311 2447 214.00 16 72.97 Changed Etoposide-induced protein 2.4 (EI24)
EIAV_GP90 PF00971 Family 3 0 0.00 0 0.00 Changed EIAV coat protein, gp90
EIAV_Rev PF11129 Family 2 0 0.00 0 0.00 Changed Rev protein of equine infectious anaemia virus
eIF-1a PF01176 Domain 422 6341 63.70 46 65.60 Changed Translation initiation factor 1A / IF-1
eIF-3c_N PF05470 Family 7 1144 435.90 32 66.09 Changed Eukaryotic translation initiation factor 3 subunit 8 N-terminus
eIF-3_zeta PF05091 Family 103 950 445.80 41 88.73 Changed Eukaryotic translation initiation factor 3 subunit 7 (eIF-3)
eIF-4B PF06273 Family 9 321 258.30 26 80.31 Changed Plant specific eukaryotic initiation factor 4B
eIF-5a PF01287 Domain 51 1372 67.50 39 36.23 Changed Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
eIF-5_eIF-2B PF01873 Family 198 2116 116.40 39 34.73 Changed Domain found in IF2B/IF5
eIF-6 PF01912 Family 149 1153 185.80 56 77.65 Changed eIF-6 family
eIF2A PF08662 Family 19 2542 173.90 22 29.15 Changed Eukaryotic translation initiation factor eIF2A
eIF2_C PF09173 Domain 113 1142 89.00 55 18.97 Changed Initiation factor eIF2 gamma, C terminal
eIF3g PF12353 Family 110 892 118.80 33 36.78 Changed Eukaryotic translation initiation factor 3 subunit G
eIF3_N PF09440 Domain 115 810 127.50 35 29.24 Changed eIF3 subunit 6 N terminal domain
eIF3_p135 PF12807 Family 160 1230 152.70 27 11.71 Changed Translation initiation factor eIF3 subunit 135
eIF3_subunit PF08597 Family 165 865 229.90 27 92.37 Changed Translation initiation factor eIF3 subunit
EIF4E-T PF10477 Family 9 342 440.70 21 61.62 Changed Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E
EIF_2_alpha PF07541 Family 191 1106 113.70 38 36.60 Changed Eukaryotic translation initiation factor 2 alpha subunit
eIF_4EBP PF05456 Family 46 341 96.80 44 75.41 Changed Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
eIF_4G1 PF12152 Domain 51 464 69.90 41 5.64 Changed Eukaryotic translation initiation factor 4G1
EII-GUT PF03608 Family 49 263 164.60 52 87.18 Changed PTS system enzyme II sorbitol-specific factor
EII-Sor PF03609 Family 297 1569 231.30 29 86.04 Changed PTS system sorbose-specific iic component
EIIA-man PF03610 Family 27 3596 113.90 21 40.64 Changed PTS system fructose IIA component
EIIBC-GUT_C PF07663 Family 25 252 91.90 69 28.16 Changed Sorbitol phosphotransferase enzyme II C-terminus
EIIBC-GUT_N PF03612 Family 64 269 173.90 44 53.96 Changed Sorbitol phosphotransferase enzyme II N-terminus
EIIC-GAT PF03611 Family 143 1521 376.20 24 86.71 Changed PTS system sugar-specific permease component
EIID-AGA PF03613 Family 295 1602 262.20 34 92.75 Changed PTS system mannose/fructose/sorbose family IID component
EIN3 PF04873 Family 10 418 217.90 55 43.23 Changed Ethylene insensitive 3
Eisosome1 PF12757 Family 90 287 123.70 31 14.25 Changed Eisosome protein 1
EKLF_TAD1 PF16832 Domain 2 31 26.40 81 7.59 Changed Erythroid krueppel-like transcription factor, transactivation 1
EKLF_TAD2 PF16833 Domain 12 33 26.90 65 7.71 Changed Erythroid krueppel-like transcription factor, transactivation 2
EKR PF10371 Domain 147 1363 55.50 41 4.76 Changed Domain of unknown function
ELF PF03317 Family 8 17 92.60 62 62.82 Changed ELF protein
Elf-1_N PF12310 Family 19 271 89.40 44 16.89 Changed Transcription factor protein N terminal
Elf1 PF05129 Domain 149 874 76.60 43 61.75 Changed Transcription elongation factor Elf1 like
ELFV_dehydrog PF00208 Domain 97 7780 211.20 26 47.39 Changed Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
ELFV_dehydrog_N PF02812 Domain 420 6650 124.90 38 29.36 Changed Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
ELH PF02323 Family 4 5 95.60 5 60.20 Changed Egg-laying hormone precursor
Elicitin PF00964 Domain 69 492 87.50 22 42.80 Changed Elicitin
ELK PF03789 Domain 32 673 21.90 52 6.85 Changed ELK domain
ELL PF10390 Family 35 521 235.30 32 40.90 Changed RNA polymerase II elongation factor ELL
ELM2 PF01448 Family 214 1952 56.10 29 7.69 Changed ELM2 domain
ELMO_CED12 PF04727 Family 230 2155 164.30 24 31.99 Changed ELMO/CED-12 family
ELO PF01151 Family 150 4072 226.60 26 79.03 Changed GNS1/SUR4 family
EloA-BP1 PF15870 Family 28 466 121.30 27 15.46 Changed ElonginA binding-protein 1
Elong-fact-P_C PF09285 Domain 478 4886 56.00 48 29.58 Changed Elongation factor P, C-terminal
Elongin_A PF06881 Family 119 754 103.10 26 21.85 Changed RNA polymerase II transcription factor SIII (Elongin) subunit A
Elong_Iki1 PF10483 Family 90 541 252.20 21 78.41 Changed Elongator subunit Iki1
ELP6 PF09807 Family 17 478 202.90 22 82.79 Changed Elongation complex protein 6
ELYS PF13934 Family 114 570 221.30 24 24.68 Changed Nuclear pore complex assembly
ELYS-bb PF16687 Domain 5 183 375.10 34 23.49 Changed beta-propeller of ELYS nucleoporin
EMA PF02488 Family 2 12 241.80 37 90.69 Changed Merozoite Antigen
Emaravirus_P4 PF16505 Family 2 0 0.00 0 0.00 Changed P4 movement protein of Emaravirus, and the 30K superfamily
EMG1 PF03587 Family 137 1064 193.40 44 76.99 Changed EMG1/NEP1 methyltransferase
EMI PF07546 Domain 126 874 67.70 32 11.24 Changed EMI domain
EMP24_GP25L PF01105 Domain 215 4926 176.30 22 74.15 Changed emp24/gp25L/p24 family/GOLD
EMP70 PF02990 Family 355 3355 447.70 35 81.84 Changed Endomembrane protein 70
EmrE PF13536 Family 53 237 260.50 45 83.16 Changed Putative multidrug resistance efflux transporter
Enamelin PF15362 Family 16 48 800.40 58 78.21 Changed Enamelin
End3 PF12761 Family 47 292 187.80 44 41.88 Changed Actin cytoskeleton-regulatory complex protein END3
EndIII_4Fe-2S PF10576 Domain 499 3022 17.00 50 6.62 Changed Iron-sulfur binding domain of endonuclease III
Endomucin PF07010 Family 11 86 128.60 55 88.79 Changed Endomucin
Endonuc-BglII PF09195 Domain 9 117 177.20 22 84.01 Changed Restriction endonuclease BglII
Endonuc-BsobI PF09194 Domain 9 30 277.60 49 96.24 Changed Restriction endonuclease BsobI
Endonuc-dimeris PF09124 Domain 2 10 45.20 29 40.54 Changed T4 recombination endonuclease VII, dimerisation
Endonuc-EcoRV PF09233 Domain 9 52 206.30 38 87.79 Changed Restriction endonuclease EcoRV
Endonuc-FokI_C PF09254 Domain 6 31 175.00 35 33.03 Changed Restriction endonuclease FokI, C terminal
Endonuc-HincII PF09226 Domain 3 9 250.00 51 96.15 Changed Restriction endonuclease HincII
Endonuc-MspI PF09208 Domain 5 12 214.30 31 67.26 Changed Restriction endonuclease MspI
Endonuc-PvuII PF09225 Domain 4 11 152.20 54 74.43 Changed Restriction endonuclease PvuII
Endonuclease_1 PF04231 Family 14 1097 204.50 27 49.81 Changed Endonuclease I
Endonuclease_5 PF04493 Family 167 1269 187.80 34 76.87 Changed Endonuclease V
Endonuclease_7 PF02945 Domain 16 238 78.10 25 18.71 Changed Recombination endonuclease VII
Endonuclease_NS PF01223 Domain 56 2876 218.70 21 52.40 Changed DNA/RNA non-specific endonuclease
Endonuclea_NS_2 PF13930 Domain 20 760 130.50 24 29.78 Changed DNA/RNA non-specific endonuclease
Endonuc_BglI PF14562 Domain 1 5 285.20 43 97.07 Changed Restriction endonuclease BglI
Endonuc_Holl PF10107 Family 10 70 127.70 35 80.04 Changed Endonuclease related to archaeal Holliday junction resolvase
Endonuc_subdom PF09062 Domain 2 3 78.70 56 4.21 Changed PI-PfuI Endonuclease subdomain
Endopep_inhib PF16800 Domain 13 61 144.70 20 55.29 Changed IseA DL-endopeptidase inhibitor
Endostatin PF06482 Domain 40 543 230.70 36 26.57 Changed Collagenase NC10 and Endostatin
Endosulfine PF04667 Family 32 1124 80.90 33 55.74 Changed cAMP-regulated phosphoprotein/endosulfine conserved region
Endothelin PF00322 Repeat 6 238 28.50 78 15.56 Changed Endothelin family
Endotoxin_C PF03944 Domain 80 16 125.80 13 13.79 Changed delta endotoxin
Endotoxin_M PF00555 Domain 36 1 210.00 100 31.48 Changed delta endotoxin
Endotoxin_mid PF09131 Domain 3 4 139.00 26 35.30 Changed Bacillus thuringiensis delta-Endotoxin, middle domain
Endotoxin_N PF03945 Domain 5 142 194.90 17 33.59 Changed delta endotoxin, N-terminal domain
EndoU_bacteria PF14436 Family 54 213 122.50 17 18.55 Changed Bacterial EndoU nuclease
End_beta_barrel PF12195 Domain 3 1 77.00 100 16.89 Changed Beta barrel domain of bacteriophage endosialidase
End_beta_propel PF12217 Domain 3 1 117.00 100 37.74 Changed Catalytic beta propeller domain of bacteriophage endosialidase
End_N_terminal PF12218 Domain 4 1 56.00 100 5.84 Changed N terminal extension of bacteriophage endosialidase
End_tail_spike PF12219 Domain 5 1 90.00 100 18.91 Changed Catalytic domain of bacteriophage endosialidase
Engrail_1_C_sig PF10525 Domain 20 271 30.40 62 10.38 Changed Engrailed homeobox C-terminal signature domain
Enkurin PF13864 Family 137 597 96.20 27 30.26 Changed Calmodulin-binding
Eno-Rase_FAD_bd PF07055 Family 126 560 63.90 48 16.30 Changed Enoyl reductase FAD binding domain
Eno-Rase_NADH_b PF12242 Family 132 552 78.90 58 20.02 Changed NAD(P)H binding domain of trans-2-enoyl-CoA reductase
ENOD40 PF08247 Family 4 1 12.00 100 100.00 Changed ENOD40 protein
ENOD93 PF03386 Family 12 255 74.00 57 64.92 Changed Early nodulin 93 ENOD93 protein
Enolase_C PF00113 Domain 9 6571 273.90 50 65.78 Changed Enolase, C-terminal TIM barrel domain
Enolase_N PF03952 Domain 785 6300 127.90 56 30.10 Changed Enolase, N-terminal domain
Enoyl_reductase PF12241 Family 98 569 232.10 54 59.39 Changed Trans-2-enoyl-CoA reductase catalytic region
ENT PF03735 Family 54 821 66.00 42 12.27 Changed ENT domain
EntA_Immun PF08951 Family 62 323 71.20 17 54.23 Changed Enterocin A Immunity
Entericidin PF08085 Family 99 686 20.70 48 43.61 Changed Entericidin EcnA/B family
Enterotoxin_a PF01375 Domain 6 269 190.00 20 34.31 Changed Heat-labile enterotoxin alpha chain
Enterotoxin_b PF01376 Domain 1 1 102.00 100 82.26 Changed Heat-labile enterotoxin beta chain
Enterotoxin_HS1 PF08090 Family 2 0 0.00 0 0.00 Changed Heat stable E.coli enterotoxin 1
Enterotoxin_ST PF02048 Family 6 2 51.50 29 65.19 Changed Heat-stable enterotoxin ST
ENTH PF01417 Domain 63 2515 119.80 39 22.24 Changed ENTH domain
Env-gp36 PF09590 Family 5 0 0.00 0 0.00 Changed Lentivirus surface glycoprotein
EnY2 PF10163 Family 108 604 79.00 35 58.88 Changed Transcription factor e(y)2
EOS1 PF12326 Family 31 317 122.10 26 33.78 Changed N-glycosylation protein
EP400_N PF15790 Family 5 162 384.60 64 18.57 Changed E1A-binding protein p400, N-terminal
Ependymin PF00811 Family 50 241 123.00 30 55.57 Changed Ependymin
EPF PF17181 Family 51 716 60.00 41 48.73 Changed Epidermal patterning factor proteins
EphA2_TM PF14575 Domain 183 1623 72.60 43 8.69 Changed Ephrin type-A receptor 2 transmembrane domain
Ephrin PF00812 Domain 44 994 123.90 34 45.66 Changed Ephrin
Ephrin_lbd PF01404 Domain 67 1482 167.60 50 19.33 Changed Ephrin receptor ligand binding domain
Ephrin_rec_like PF07699 Family 29 4765 47.00 30 7.65 Changed Putative ephrin-receptor like
Epiglycanin_C PF14654 Domain 6 36 93.10 59 14.48 Changed Mucin, catalytic, TM and cytoplasmic tail region
Epiglycanin_TR PF05647 Repeat 15 263 59.30 49 97.89 Changed Tandem-repeating region of mucin, epiglycanin-like
Epimerase PF01370 Family 96 36991 222.60 18 66.24 Changed NAD dependent epimerase/dehydratase family
Epimerase_2 PF02350 Family 94 3831 329.10 30 86.98 Changed UDP-N-acetylglucosamine 2-epimerase
EPL1 PF10513 Family 119 2175 164.90 20 17.65 Changed Enhancer of polycomb-like
EpmC PF04315 Family 42 329 156.20 50 85.12 Changed Elongation factor P hydroxylase
EpoR_lig-bind PF09067 Domain 12 530 98.00 32 19.12 Changed Erythropoietin receptor, ligand binding
EPO_TPO PF00758 Domain 13 151 148.60 37 58.10 Changed Erythropoietin/thrombopoietin
EppA_BapA PF07268 Family 2 2 137.00 61 79.88 Changed Exported protein precursor (EppA/BapA)
EpsG PF14897 Family 66 671 321.40 15 88.77 Changed EpsG family
Epsilon_antitox PF08998 Domain 2 13 84.80 49 80.92 Changed Bacterial epsilon antitoxin
EPSP_synthase PF00275 Family 20 10231 387.90 26 82.86 Changed EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
EPTP PF03736 Repeat 227 2889 44.50 24 20.13 Changed EPTP domain
EpuA PF11772 Family 35 278 45.60 36 53.76 Changed DNA-directed RNA polymerase subunit beta
EPV_E5 PF08135 Family 1 1 43.00 100 100.00 Changed Major transforming protein E5 family
Equine_IAV_S2 PF06502 Family 2 0 0.00 0 0.00 Changed Equine infectious anaemia virus S2 protein
ER PF01133 Family 53 475 93.00 48 56.73 Changed Enhancer of rudimentary
ER-remodelling PF14755 Domain 5 14 90.90 42 23.94 Changed Intracellular membrane remodeller
ERAP1_C PF11838 Domain 797 5125 292.50 18 35.77 Changed ERAP1-like C-terminal domain
ERbeta_N PF12497 Family 18 125 110.30 56 20.61 Changed Estrogen receptor beta
ERCC3_RAD25_C PF16203 Domain 40 1777 211.00 42 31.89 Changed ERCC3/RAD25/XPB C-terminal helicase
ERCC4 PF02732 Domain 155 2519 146.60 21 20.29 Changed ERCC4 domain
ERF PF04404 Family 29 324 147.80 19 62.70 Changed ERF superfamily
eRF1_1 PF03463 Domain 277 2262 123.90 32 29.90 Changed eRF1 domain 1
eRF1_2 PF03464 Domain 21 2226 130.10 32 31.25 Changed eRF1 domain 2
eRF1_3 PF03465 Domain 34 2346 117.30 33 28.56 Changed eRF1 domain 3
Erf4 PF10256 Domain 125 1008 112.50 28 40.47 Changed Golgin subfamily A member 7/ERF4 family
Erg28 PF03694 Family 131 620 111.20 33 72.71 Changed Erg28 like protein
ERG2_Sigma1R PF04622 Family 110 639 193.60 36 82.25 Changed ERG2 and Sigma1 receptor like protein
ERG4_ERG24 PF01222 Family 5 2035 381.10 30 85.30 Changed Ergosterol biosynthesis ERG4/ERG24 family
ERGIC_N PF13850 Domain 326 2078 88.70 31 21.73 Changed Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
ERK-JNK_inhib PF15002 Family 18 208 175.90 35 72.03 Changed ERK and JNK pathways, inhibitor
ERM PF00769 Family 71 881 226.20 33 39.33 Changed Ezrin/radixin/moesin family
ErmC PF06308 Family 1 2 29.00 96 100.00 Changed 23S rRNA methylase leader peptide (ErmC)
ERO1 PF04137 Family 171 1111 341.00 36 73.58 Changed Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
ERp29 PF07749 Domain 163 689 91.70 31 25.37 Changed Endoplasmic reticulum protein ERp29, C-terminal domain
ERp29_N PF07912 Domain 3 134 117.50 50 43.15 Changed ERp29, N-terminal domain
Erp_C PF06780 Family 4 8 134.80 33 38.28 Changed Erp protein C-terminus
Erv26 PF04148 Family 76 549 186.80 38 83.29 Changed Transmembrane adaptor Erv26
Erythro-docking PF09277 Domain 2 12 53.50 43 3.12 Changed Erythronolide synthase, docking
Erythrovirus_X PF06795 Family 1 1 81.00 100 100.00 Changed Erythrovirus X protein
Erythro_esteras PF05139 Family 176 995 325.70 24 73.07 Changed Erythromycin esterase
Eryth_link_C PF16915 Domain 13 0 0.00 0 0.00 Changed Annelid erythrocruorin linker subunit C-terminus
Ery_res_leader1 PF08051 Family 3 7 15.00 72 6.25 Changed Erythromycin resistance leader peptide
Ery_res_leader2 PF08057 Family 1 0 0.00 0 0.00 Changed Erythromycin resistance leader peptide
ER_lumen_recept PF00810 Family 251 1828 139.00 41 57.35 Changed ER lumen protein retaining receptor
Es2 PF09751 Family 63 878 319.00 25 74.65 Changed Nuclear protein Es2
ESAG1 PF03238 Family 11 13 228.80 56 70.05 Changed ESAG protein
ESCRT-II PF05871 Family 153 800 133.20 34 56.47 Changed ESCRT-II complex subunit
ESM4 PF15952 Family 14 81 157.10 28 95.06 Changed Enhancer of split M4 family
ESP PF16590 Family 13 26 80.70 35 74.07 Changed Exocrine gland-secreting peptide
EspA PF03433 Family 7 40 157.80 28 91.65 Changed EspA-like secreted protein
EspB PF05802 Family 3 10 188.40 16 86.78 Changed Enterobacterial EspB protein
EspF PF04806 Repeat 3 1 34.00 100 3.61 Changed EspF protein repeat
EspG PF06872 Family 4 2 390.00 20 97.74 Changed EspG protein
ESPR PF13018 Domain 149 696 23.80 42 1.20 Changed Extended Signal Peptide of Type V secretion system
ESR1_C PF12743 Domain 19 88 43.80 60 8.63 Changed Oestrogen-type nuclear receptor final C-terminal
EssA PF10661 Family 4 32 132.80 19 81.21 Changed WXG100 protein secretion system (Wss), protein EssA
ESSS PF10183 Family 17 474 107.40 24 74.10 Changed ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
EST1 PF10374 Domain 131 1139 121.40 22 12.82 Changed Telomerase activating protein Est1
EST1_DNA_bind PF10373 Domain 55 1757 247.10 18 28.52 Changed Est1 DNA/RNA binding domain
Esterase PF00756 Domain 20 8641 233.50 16 70.58 Changed Putative esterase
Esterase_phd PF10503 Family 2 2095 182.90 23 50.48 Changed Esterase PHB depolymerase
ESX-1_EspG PF14011 Family 135 492 236.00 19 90.08 Changed EspG family
ET PF01684 Family 55 364 77.40 36 75.29 Changed ET module
ETAA1 PF15350 Family 18 147 494.20 32 92.82 Changed Ewing's tumour-associated antigen 1 homologue
ETC_C1_NDUFA4 PF04800 Family 164 1276 94.70 41 58.90 Changed ETC complex I subunit conserved region
ETC_C1_NDUFA5 PF04716 Family 128 703 68.80 37 36.52 Changed ETC complex I subunit conserved region
ETF PF01012 Domain 129 9720 178.40 23 60.45 Changed Electron transfer flavoprotein domain
ETF_alpha PF00766 Domain 518 4987 83.40 55 24.77 Changed Electron transfer flavoprotein FAD-binding domain
ETF_QO PF05187 Family 44 2218 99.50 51 19.74 Changed Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S
EthD PF07110 Domain 56 1731 89.60 18 55.53 Changed EthD domain
ETM PF17577 Family 1 1 109.00 100 96.46 New ECORI-T site protein ETM
Etmic-2 PF06670 Family 2 12 179.40 31 99.40 Changed Microneme protein Etmic-2
ETRAMP PF09716 Family 42 202 88.80 25 52.09 Changed Malarial early transcribed membrane protein (ETRAMP)
Ets PF00178 Domain 160 3769 79.50 51 19.71 Changed Ets-domain
ETS_PEA3_N PF04621 Family 36 356 280.10 51 68.42 Changed PEA3 subfamily ETS-domain transcription factor N terminal domain
ETX_MTX2 PF03318 Family 15 236 188.40 16 55.96 Changed Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2
Euplotes_phero PF05842 Family 6 0 0.00 0 0.00 Changed Euplotes octocarinatus mating pheromone protein
EURL PF06937 Family 4 106 262.40 67 94.21 Changed EURL protein
EutA PF06277 Family 15 235 434.50 36 96.50 Changed Ethanolamine utilisation protein EutA
EutB PF06751 Family 115 695 424.80 57 92.06 Changed Ethanolamine ammonia lyase large subunit (EutB)
EutC PF05985 Family 178 686 230.00 41 80.14 Changed Ethanolamine ammonia-lyase light chain (EutC)
EutH PF04346 Family 59 271 346.30 41 93.61 Changed Ethanolamine utilisation protein, EutH
EutK_C PF16365 Domain 2 18 53.20 68 34.80 Changed Ethanolamine utilization protein EutK C-terminus
EutN_CcmL PF03319 Domain 194 768 81.70 39 88.78 Changed Ethanolamine utilisation protein EutN/carboxysome
EutQ PF06249 Domain 4 445 114.00 27 73.28 Changed Ethanolamine utilisation protein EutQ
EVC2_like PF12297 Family 16 109 377.40 49 35.09 Changed Ellis van Creveld protein 2 like protein
EVE PF01878 Domain 136 2133 139.80 34 71.32 Changed EVE domain
EVI2A PF05399 Family 11 87 207.00 47 88.32 Changed Ectropic viral integration site 2A protein (EVI2A)
Evr1_Alr PF04777 Family 345 1937 95.10 30 27.76 Changed Erv1 / Alr family
ExbD PF02472 Family 45 7225 132.90 22 88.85 Changed Biopolymer transport protein ExbD/TolR
Exc PF07825 Domain 2 41 74.60 27 87.57 Changed Excisionase-like protein
Excalibur PF05901 Domain 159 868 38.00 38 18.91 Changed Excalibur calcium-binding domain
Exo5 PF09810 Family 70 845 223.00 21 66.43 Changed Exonuclease V - a 5' deoxyribonuclease
Exo70 PF03081 Family 289 2461 322.70 22 57.09 Changed Exo70 exocyst complex subunit
Exo84_C PF16528 Domain 31 888 198.80 25 27.98 Changed Exocyst component 84 C-terminal
ExoD PF06055 Family 157 703 178.60 26 86.85 Changed Exopolysaccharide synthesis, ExoD
Exonuc_VIII PF06630 Family 2 24 158.00 32 20.05 Changed Enterobacterial exodeoxyribonuclease VIII
Exonuc_VII_L PF02601 Family 546 4789 229.20 26 68.83 Changed Exonuclease VII, large subunit
Exonuc_VII_S PF02609 Family 868 3654 51.80 35 64.09 Changed Exonuclease VII small subunit
Exonuc_V_gamma PF04257 Family 59 1169 617.20 24 59.17 Changed Exodeoxyribonuclease V, gamma subunit
Exonuc_X-T_C PF08411 Family 132 618 256.30 34 55.18 Changed Exonuclease C-terminal
EXOSC1 PF10447 Domain 12 794 55.50 38 27.30 Changed Exosome component EXOSC1/CSL4
Exosortase_EpsH PF09721 Family 190 1039 234.60 18 67.15 Changed Transmembrane exosortase (Exosortase_EpsH)
Exostosin PF03016 Family 32 4176 265.90 21 52.37 Changed Exostosin family
Exotox-A_bind PF09101 Domain 2 5 191.60 29 27.10 Changed Exotoxin A binding
Exotox-A_cataly PF09009 Domain 1 5 207.20 41 44.20 Changed Exotoxin A catalytic
Exotox-A_target PF09102 Domain 1 3 138.70 59 21.63 Changed Exotoxin A, targeting
Exo_endo_phos PF03372 Domain 320 24141 270.20 12 59.83 Changed Endonuclease/Exonuclease/phosphatase family
Exo_endo_phos_2 PF14529 Domain 71 4318 116.00 18 18.51 Changed Endonuclease-reverse transcriptase
EXS PF03124 Family 339 2108 297.30 27 49.90 Changed EXS family
ExsD PF16806 Domain 4 14 242.40 27 83.21 Changed Antiactivator protein ExsD
Extensin-like_C PF06904 Family 88 757 169.20 33 62.36 Changed Extensin-like protein C-terminus
Extensin_1 PF02095 Repeat 13 516 9.40 75 79.05 Changed Extensin-like protein repeat
Extensin_2 PF04554 Family 14 1063 49.50 70 61.44 Changed Extensin-like region
EZH2_WD-Binding PF11616 Family 12 226 30.00 68 4.54 Changed WD repeat binding protein EZH2
EzrA PF06160 Coiled-coil 90 483 529.20 23 95.50 Changed Septation ring formation regulator, EzrA
E_Pc_C PF06752 Family 18 220 220.90 54 29.08 Changed Enhancer of Polycomb C-terminus
E_raikovi_mat PF06360 Family 6 0 0.00 0 0.00 Changed Euplotes raikovi mating pheromone
New Top twenty Numbers A B C D E F G H I J K L M N O P Q R S T U V W X Y Z