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Browse Pfam families

New Top twenty Numbers A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
ID Accession Type Number of sequences Average length Average %id Average coverage Has 3D Change status Description
Seed Full
E1-E2_ATPase PF00122 Family 79 63280 186.10 24 21.50 Changed E1-E2 ATPase
E1-N PF14463 Family 2 5 147.00 37 32.61 Changed E1 N-terminal domain
E1_4HB PF16191 Domain 270 1632 69.80 40 6.64 Changed Ubiquitin-activating enzyme E1 four-helix bundle
E1_DerP2_DerF2 PF02221 Domain 91 2856 127.10 19 62.46 Changed ML domain
E1_dh PF00676 Family 13 21424 298.80 25 49.14 Changed Dehydrogenase E1 component
E1_FCCH PF16190 Domain 166 1683 71.00 47 6.78 Changed Ubiquitin-activating enzyme E1 FCCH domain
E1_UFD PF09358 Domain 172 1627 90.70 37 8.82 Changed Ubiquitin fold domain
E2 PF08199 Family 1 1 37.00 100 100.00 Changed Bacteriophage E2-like protein
E2F_CC-MB PF16421 Domain 156 1639 97.30 39 24.72 Changed E2F transcription factor CC-MB domain
E2F_TDP PF02319 Domain 191 4249 71.30 41 19.50 Changed E2F/DP family winged-helix DNA-binding domain
E2R135 PF11570 Coiled-coil 1 6 83.80 28 27.91 Changed Coiled-coil receptor-binding R-domain of colicin E2
E2_bind PF08825 Domain 144 1002 83.90 37 18.59 Changed E2 binding domain
E3_binding PF02817 Family 969 18000 35.70 41 7.84 Changed e3 binding domain
E3_UbLigase_EDD PF11547 Family 8 410 51.70 80 1.92 Changed E3 ubiquitin ligase EDD
E3_UbLigase_R4 PF13764 Family 30 645 596.40 35 19.06 Changed E3 ubiquitin-protein ligase UBR4
E3_UbLigase_RBR PF18091 Domain 10 284 90.30 43 5.82 New E3 Ubiquitin Ligase RBR C-terminal domain
E3_UFM1_ligase PF09743 Family 62 636 245.80 34 35.07 Changed E3 UFM1-protein ligase 1
E6 PF00518 Family 12 203 110.10 31 73.23 Changed Early Protein (E6)
E7 PF00527 Family 9 202 86.80 32 87.80 Changed E7 protein, Early protein
E7R PF17467 Family 2 8 60.00 89 39.38 Changed Viral Protein E7
EABR PF12180 Domain 12 278 33.70 50 8.05 Changed TSG101 and ALIX binding domain of CEP55
Ead_Ea22 PF13935 Family 29 102 135.50 29 65.62 Changed Ead/Ea22-like protein
EAF PF09816 Domain 106 1087 101.90 29 28.45 Changed RNA polymerase II transcription elongation factor
Eaf7 PF07904 Family 60 852 106.80 26 38.53 Changed Chromatin modification-related protein EAF7
EAGR_box PF16713 Domain 22 32 33.80 43 9.51 Changed Enriched in aromatic and glycine Residues box
EAL PF00563 Domain 71 45315 228.40 30 33.77 Changed EAL domain
EamA PF00892 Family 97 129167 135.60 15 77.91 Changed EamA-like transporter family
EAP30 PF04157 Family 230 2204 215.80 26 57.42 Changed EAP30/Vps36 family
Eapp_C PF10238 Family 63 492 124.50 36 51.18 Changed E2F-associated phosphoprotein
EAR PF07897 Family 28 323 37.70 53 10.69 Changed Ethylene-responsive binding factor-associated repression
EarP PF10093 Family 85 652 354.30 41 96.32 Changed Elongation-Factor P (EF-P) rhamnosyltransferase EarP
EAV_GP5 PF15981 Family 1 1 80.00 100 31.37 Changed Envelope glycoprotein GP 5 of equine arteritis virus
EAV_GS PF01309 Family 1 1 196.00 100 86.34 Changed Equine arteritis virus small envelope glycoprotein
EB PF01683 Family 180 5203 56.20 25 22.92 Changed EB module
EB1 PF03271 Family 164 1792 41.70 52 13.86 Changed EB1-like C-terminal motif
EB1_binding PF05937 Family 6 143 169.70 77 6.27 Changed EB-1 Binding Domain
EBA-175_VI PF11556 Family 11 115 80.30 50 5.97 Changed Erythrocyte binding antigen 175
Ebola_NP PF05505 Family 2 6 612.70 45 93.09 Changed Ebola nucleoprotein
EBP PF05241 Family 171 1426 176.00 28 67.02 Changed Emopamil binding protein
Ebp2 PF05890 Family 133 1156 255.20 32 74.60 Changed Eukaryotic rRNA processing protein EBP2
EBP50_C PF09007 Domain 34 352 94.10 39 37.50 Changed EBP50, C-terminal
EbsA PF17255 Family 26 248 128.30 22 92.02 Changed EbsA-like protein
EBV-NA1 PF02905 Domain 2 5 146.80 64 26.51 Changed Epstein Barr virus nuclear antigen-1, DNA-binding domain
EBV-NA3 PF05009 Family 3 12 257.10 38 26.53 Changed Epstein-Barr virus nuclear antigen 3 (EBNA-3)
EB_dh PF09459 Domain 26 625 239.90 18 64.10 Changed Ethylbenzene dehydrogenase
EC042_2821 PF18740 Domain 44 118 174.30 18 53.12 New EC042_2821-lke REase
EccE PF11203 Family 54 868 100.50 27 22.98 Changed Putative type VII ESX secretion system translocon, EccE
ECD PF18432 Domain 4 275 101.60 82 6.11 New Extracellular Cadherin domain
ECF-ribofla_trS PF07155 Family 47 2409 161.10 21 81.30 Changed ECF-type riboflavin transporter, S component
ECF_trnsprt PF12822 Family 57 4260 168.90 17 80.29 Changed ECF transporter, substrate-specific component
ECH_1 PF00378 Domain 9 65679 233.30 24 69.44 Changed Enoyl-CoA hydratase/isomerase
ECH_2 PF16113 Domain 286 5531 298.80 33 80.28 Changed Enoyl-CoA hydratase/isomerase
EcKinase PF02958 Family 51 4111 243.40 19 61.81 Changed Ecdysteroid kinase
Ecl1 PF12855 Family 68 741 159.80 19 75.32 Changed ECL1/2/3 zinc binding proteins
Eclosion PF04736 Family 9 110 59.60 50 61.17 Changed Eclosion hormone
ECM1 PF05782 Family 12 155 311.30 34 92.69 Changed Extracellular matrix protein 1 (ECM1)
ECM11 PF15463 Family 68 329 134.70 29 27.22 Changed Extracellular mutant protein 11
Ecm29 PF13001 Family 118 1133 411.20 25 27.55 Changed Proteasome stabiliser
Ecm33 PF12454 Family 17 195 40.00 44 10.01 Changed GPI-anchored cell wall organization protein
Eco57I PF07669 Domain 17 1944 110.50 23 12.32 Changed Eco57I restriction-modification methylase
EcoEI_R_C PF08463 Family 223 1919 156.50 19 17.55 Changed EcoEI R protein C-terminal
EcoR124_C PF12008 Domain 175 1239 264.30 21 28.36 Changed Type I restriction and modification enzyme - subunit R C terminal
EcoRI PF02963 Domain 7 48 213.80 49 88.03 Changed Restriction endonuclease EcoRI
EcoRII-C PF09019 Domain 8 199 161.30 36 44.04 Changed EcoRII C terminal
EcoRII-N PF09217 Domain 6 89 128.20 32 36.79 Changed Restriction endonuclease EcoRII, N-terminal
EcoRI_methylase PF13651 Family 22 329 274.20 39 92.37 Changed Adenine-specific methyltransferase EcoRI
Ecotin PF03974 Family 52 357 122.20 40 72.93 Changed Ecotin
EcpB_C PF18649 Domain 15 46 73.50 47 33.07 New EcpB C-terminal domain
ECR1_N PF14382 Domain 243 1869 38.50 35 13.93 Changed Exosome complex exonuclease RRP4 N-terminal region
EcsB PF05975 Family 65 964 346.60 22 94.82 Changed Bacterial ABC transporter protein EcsB
EcsC PF12787 Family 86 1978 229.00 19 85.05 Changed EcsC protein family
ECSCR PF15820 Family 2 87 96.20 65 42.91 Changed Endothelial cell-specific chemotaxis regulator
ECSIT PF06239 Family 19 319 196.30 37 50.78 Changed Evolutionarily conserved signalling intermediate in Toll pathway
ECSIT_C PF14784 Domain 39 269 118.90 32 31.58 Changed C-terminal domain of the ECSIT protein
Ectatomin PF06457 Domain 2 0 0.00 0 0.00 Changed Ectatomin
ecTbetaR2 PF08917 Domain 20 223 109.10 53 21.47 Changed Transforming growth factor beta receptor 2 ectodomain
Ectoine_synth PF06339 Family 33 1322 126.30 48 92.81 Changed Ectoine synthase
Edc3_linker PF16598 Family 7 136 90.00 72 18.65 Changed Linker region of enhancer of mRNA-decapping protein 3
EDR1 PF14381 Family 68 1802 189.60 31 23.93 Changed Ethylene-responsive protein kinase Le-CTR1
EDS1_EP PF18117 Domain 14 436 108.30 39 18.87 New Enhanced disease susceptibility 1 protein EP domain
EELM2 PF15863 Domain 8 105 158.80 50 28.24 Changed Extended EGL-27 and MTA1 homology domain
EF-1_beta_acid PF10587 Domain 76 1343 27.50 62 9.63 Changed Eukaryotic elongation factor 1 beta central acidic region
EF-G-binding_N PF07299 Domain 31 317 82.80 29 38.87 Changed Elongation factor G-binding protein, N-terminal
EF-hand_1 PF00036 Domain 570 8511 28.60 30 9.80 Changed EF hand
EF-hand_10 PF14788 Domain 9 165 49.50 47 6.99 Changed EF hand
EF-hand_11 PF08976 Domain 2 318 89.40 28 16.64 Changed EF-hand domain
EF-hand_12 PF17901 Domain 9 23 91.70 50 12.42 New EF-hand fold domain
EF-hand_13 PF17958 Domain 11 1194 87.60 39 13.57 New EF-hand domain
EF-hand_14 PF17959 Domain 21 645 85.40 40 15.02 New EF-hand domain
EF-hand_2 PF09068 Domain 62 1802 120.50 39 10.35 Changed EF hand
EF-hand_3 PF09069 Domain 23 1780 90.30 46 7.77 Changed EF-hand
EF-hand_4 PF12763 Family 13 8007 95.00 31 16.53 Changed Cytoskeletal-regulatory complex EF hand
EF-hand_5 PF13202 Domain 96 22564 23.30 30 8.85 Changed EF hand
EF-hand_6 PF13405 Domain 580 5750 31.80 31 10.28 Changed EF-hand domain
EF-hand_7 PF13499 Domain 93 56566 68.80 26 19.92 Changed EF-hand domain pair
EF-hand_8 PF13833 Domain 36 16556 49.30 22 12.15 Changed EF-hand domain pair
EF-hand_9 PF14658 Domain 7 200 65.90 36 10.35 Changed EF-hand domain
EF-hand_like PF09279 Domain 26 2998 85.60 29 8.25 Changed Phosphoinositide-specific phospholipase C, efhand-like
EF1G PF00647 Domain 105 1413 104.00 48 25.35 Changed Elongation factor 1 gamma, conserved domain
EF1_GNE PF00736 Domain 182 2379 84.60 46 35.22 Changed EF-1 guanine nucleotide exchange domain
efb-c PF12199 Domain 2 5 63.40 50 52.83 Changed Extracellular fibrinogen binding protein C terminal
EFF-AFF PF14884 Family 2 235 359.00 25 87.14 Changed Type I membrane glycoproteins cell-cell fusogen
Effector_1 PF04518 Family 5 32 333.10 28 54.95 Changed Effector from type III secretion system
Efg1 PF10153 Family 128 746 112.40 34 37.37 Changed rRNA-processing protein Efg1
EFG_C PF00679 Domain 124 36289 87.90 28 12.90 Changed Elongation factor G C-terminus
EFG_II PF14492 Domain 82 19447 73.90 39 10.06 Changed Elongation Factor G, domain II
EFG_IV PF03764 Domain 66 17997 118.80 33 16.53 Changed Elongation factor G, domain IV
EFhand_Ca_insen PF08726 Domain 18 1892 68.10 43 5.69 Changed Ca2+ insensitive EF hand
EFP PF01132 Domain 852 8909 53.80 32 28.41 Changed Elongation factor P (EF-P) OB domain
EFP_N PF08207 Domain 177 9320 57.60 34 30.64 Changed Elongation factor P (EF-P) KOW-like domain
efThoc1 PF11957 Family 49 1193 413.50 27 68.20 Changed THO complex subunit 1 transcription elongation factor
EFTUD2 PF16004 Family 148 1051 111.00 46 11.62 Changed 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
EF_assoc_1 PF08355 Family 94 1386 72.90 41 11.18 Changed EF hand associated
EF_assoc_2 PF08356 Family 75 1483 86.60 45 13.56 Changed EF hand associated
EF_TS PF00889 Family 103 9378 189.50 31 69.07 Changed Elongation factor TS
EGF PF00008 Domain 67 59219 31.80 39 8.68 Changed EGF-like domain
EGF_2 PF07974 Domain 50 5338 30.70 40 3.96 Changed EGF-like domain
EGF_3 PF12947 Domain 136 5612 36.20 40 4.47 Changed EGF domain
EGF_alliinase PF04863 Domain 19 204 55.00 59 12.76 Changed Alliinase EGF-like domain
EGF_CA PF07645 Domain 18 61668 41.80 36 11.17 Changed Calcium-binding EGF domain
EGF_MSP1_1 PF12946 Domain 9 69 37.10 38 2.54 Changed MSP1 EGF domain 1
EGF_Tenascin PF18720 Domain 1 3630 29.00 55 7.91 New Tenascin EGF domain
Egg_lysin PF01303 Domain 24 5 112.20 50 74.11 Changed Egg lysin (Sperm-lysin)
Egh16-like PF11327 Family 163 981 193.40 32 61.73 Changed Egh16-like virulence factor
EGL-1 PF11430 Family 10 24 19.50 64 19.08 Changed Programmed cell death activator EGL-1
Ehbp PF10622 Family 11 33 78.80 50 87.74 Changed Energy-converting hydrogenase B subunit P (EhbP)
EHD_N PF16880 Family 82 1446 32.60 50 5.73 Changed N-terminal EH-domain containing protein
EHN PF06441 Family 593 4664 107.70 37 26.42 Changed Epoxide hydrolase N terminus
Ehrlichia_rpt PF09528 Repeat 4 6 35.70 70 25.75 Changed Ehrlichia tandem repeat (Ehrlichia_rpt)
EH_Signature PF15611 Domain 25 223 379.30 14 77.55 Changed EH_Signature domain
EI24 PF07264 Family 309 4328 214.70 16 74.94 Changed Etoposide-induced protein 2.4 (EI24)
EIAV_GP90 PF00971 Family 3 0 0.00 0 0.00 Changed EIAV coat protein, gp90
EIAV_Rev PF11129 Family 2 0 0.00 0 0.00 Changed Rev protein of equine infectious anaemia virus
eIF-1a PF01176 Domain 417 11256 63.80 47 68.92 Changed Translation initiation factor 1A / IF-1
eIF-3c_N PF05470 Family 7 1617 440.20 31 66.60 Changed Eukaryotic translation initiation factor 3 subunit 8 N-terminus
eIF-3_zeta PF05091 Family 103 1305 453.90 40 88.62 Changed Eukaryotic translation initiation factor 3 subunit 7 (eIF-3)
eIF-4B PF06273 Family 9 486 265.80 25 80.90 Changed Plant specific eukaryotic initiation factor 4B
eIF-5a PF01287 Domain 51 1958 67.50 39 36.08 Changed Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
eIF-5_eIF-2B PF01873 Family 194 3075 115.90 37 35.10 Changed Domain found in IF2B/IF5
eIF-6 PF01912 Family 148 1686 185.80 52 78.18 Changed eIF-6 family
eIF2A PF08662 Family 18 3563 174.20 23 28.79 Changed Eukaryotic translation initiation factor eIF2A
eIF2_C PF09173 Domain 113 1690 88.70 53 18.75 Changed Initiation factor eIF2 gamma, C terminal
eIF3g PF12353 Family 109 1236 118.70 34 37.73 Changed Eukaryotic translation initiation factor 3 subunit G
eIF3m_C_helix PF18005 Domain 128 823 28.80 42 6.93 New eIF3 subunit M, C-terminal helix
eIF3_N PF09440 Domain 113 1143 127.00 36 29.42 Changed eIF3 subunit 6 N terminal domain
eIF3_p135 PF12807 Family 156 1902 152.70 28 11.65 Changed Translation initiation factor eIF3 subunit 135
eIF3_subunit PF08597 Family 165 1224 229.20 27 92.85 Changed Translation initiation factor eIF3 subunit
EIF4E-T PF10477 Family 8 557 411.60 20 61.63 Changed Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E
EIF_2_alpha PF07541 Family 189 1614 114.00 36 36.67 Changed Eukaryotic translation initiation factor 2 alpha subunit
eIF_4EBP PF05456 Family 46 472 100.30 44 69.76 Changed Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
eIF_4G1 PF12152 Domain 51 629 69.90 40 5.60 Changed Eukaryotic translation initiation factor 4G1
EII-GUT PF03608 Family 47 425 165.40 51 87.54 Changed PTS system enzyme II sorbitol-specific factor
EII-Sor PF03609 Family 293 2385 232.40 30 85.71 Changed PTS system sorbose-specific iic component
EIIA-man PF03610 Family 27 6261 114.00 22 41.48 Changed PTS system fructose IIA component
EIIBC-GUT_C PF07663 Family 25 411 92.30 68 28.36 Changed Sorbitol phosphotransferase enzyme II C-terminus
EIIBC-GUT_N PF03612 Family 62 442 173.40 45 54.15 Changed Sorbitol phosphotransferase enzyme II N-terminus
EIIC-GAT PF03611 Family 143 2405 383.30 24 86.80 Changed PTS system sugar-specific permease component
EIID-AGA PF03613 Family 291 2432 263.60 34 92.51 Changed PTS system mannose/fructose/sorbose family IID component
EIN3 PF04873 Family 10 600 223.20 58 42.85 Changed Ethylene insensitive 3
Eisosome1 PF12757 Family 89 402 124.10 32 14.29 Changed Eisosome protein 1
EKAL PF17986 Domain 5 52 52.10 55 7.55 New EMP3-KAHRP-like N-terminal domain
EKLF_TAD1 PF16832 Domain 2 38 26.50 80 7.51 Changed Erythroid krueppel-like transcription factor, transactivation 1
EKLF_TAD2 PF16833 Domain 12 39 26.90 67 7.62 Changed Erythroid krueppel-like transcription factor, transactivation 2
EKR PF10371 Domain 145 2200 55.50 41 4.71 Changed Domain of unknown function
ELF PF03317 Family 8 19 98.30 65 61.17 Changed ELF protein
Elf-1_N PF12310 Family 19 414 87.90 46 16.69 Changed Transcription factor protein N terminal
Elf1 PF05129 Domain 148 1253 76.70 43 62.35 Changed Transcription elongation factor Elf1 like
Elf4 PF07011 Domain 25 424 81.60 52 62.75 Changed Early Flowering 4 domain
ELFV_dehydrog PF00208 Domain 97 14046 210.60 27 48.12 Changed Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
ELFV_dehydrog_N PF02812 Domain 410 12323 125.00 38 29.47 Changed Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
ELH PF02323 Family 4 9 102.60 6 49.73 Changed Egg-laying hormone precursor
Elicitin PF00964 Domain 69 541 87.50 22 43.30 Changed Elicitin
ELK PF03789 Domain 30 1055 21.90 51 6.74 Changed ELK domain
ELL PF10390 Family 34 711 234.10 30 39.69 Changed RNA polymerase II elongation factor ELL
ELM2 PF01448 Family 209 2909 56.80 29 7.71 Changed ELM2 domain
ELMO_CED12 PF04727 Family 227 3087 163.70 26 33.02 Changed ELMO/CED-12 family
ELO PF01151 Family 149 5974 224.60 26 78.15 Changed GNS1/SUR4 family
EloA-BP1 PF15870 Family 26 591 119.70 28 15.60 Changed ElonginA binding-protein 1
Elong-fact-P_C PF09285 Domain 474 9037 56.00 47 29.67 Changed Elongation factor P, C-terminal
Elongin_A PF06881 Family 115 1044 102.40 27 22.15 Changed RNA polymerase II transcription factor SIII (Elongin) subunit A
Elong_Iki1 PF10483 Family 90 887 238.70 19 76.79 Changed Elongator subunit Iki1
ELP6 PF09807 Family 17 636 200.70 21 82.67 Changed Elongation complex protein 6
ELYS PF13934 Family 111 854 223.70 24 24.13 Changed Nuclear pore complex assembly
ELYS-bb PF16687 Domain 5 253 382.60 31 22.75 Changed beta-propeller of ELYS nucleoporin
EMA PF02488 Family 2 12 241.80 37 90.69 Changed Merozoite Antigen
Emaravirus_P4 PF16505 Family 2 7 328.60 30 89.32 Changed P4 movement protein of Emaravirus, and the 30K superfamily
EMC1_C PF07774 Domain 166 1252 199.80 35 22.16 Changed ER membrane protein complex subunit 1, C-terminal
EMC3_TMCO1 PF01956 Family 56 2107 170.00 26 70.29 Changed Integral membrane protein EMC3/TMCO1-like
EMG1 PF03587 Family 135 1465 194.00 44 75.53 Changed EMG1/NEP1 methyltransferase
EMI PF07546 Domain 120 1172 68.20 34 11.25 Changed EMI domain
EMP24_GP25L PF01105 Domain 215 6760 175.80 22 74.36 Changed emp24/gp25L/p24 family/GOLD
EMP70 PF02990 Family 342 4839 448.10 36 81.85 Changed Endomembrane protein 70
EmrE PF13536 Family 52 426 262.70 44 83.31 Changed Putative multidrug resistance efflux transporter
Enamelin PF15362 Family 16 66 755.60 57 77.75 Changed Enamelin
End3 PF12761 Family 47 413 189.00 44 42.76 Changed Actin cytoskeleton-regulatory complex protein END3
EndIII_4Fe-2S PF10576 Domain 493 5802 17.00 50 6.54 Changed Iron-sulfur binding domain of endonuclease III
Endomucin PF07010 Family 11 129 146.60 51 91.47 Changed Endomucin
Endonuc-BglII PF09195 Domain 9 259 180.60 24 84.03 Changed Restriction endonuclease BglII
Endonuc-BsobI PF09194 Domain 9 59 248.50 44 97.02 Changed Restriction endonuclease BsobI
Endonuc-dimeris PF09124 Domain 2 52 50.60 36 34.56 Changed T4 recombination endonuclease VII, dimerisation
Endonuc-EcoRV PF09233 Domain 9 99 202.00 35 87.98 Changed Restriction endonuclease EcoRV
Endonuc-FokI_C PF09254 Domain 6 61 171.80 29 32.81 Changed Restriction endonuclease FokI, C terminal
Endonuc-HincII PF09226 Domain 3 12 249.20 54 96.33 Changed Restriction endonuclease HincII
Endonuc-MspI PF09208 Domain 5 16 236.20 33 67.27 Changed Restriction endonuclease MspI
Endonuc-PvuII PF09225 Domain 4 24 149.00 45 77.62 Changed Restriction endonuclease PvuII
Endonuclease_1 PF04231 Family 14 2248 206.70 27 48.79 Changed Endonuclease I
Endonuclease_5 PF04493 Family 164 2160 188.30 35 77.38 Changed Endonuclease V
Endonuclease_7 PF02945 Domain 16 753 81.60 28 26.10 Changed Recombination endonuclease VII
Endonuclease_NS PF01223 Domain 56 4731 219.70 20 53.47 Changed DNA/RNA non-specific endonuclease
Endonuclea_NS_2 PF13930 Domain 19 1245 130.60 23 26.69 Changed DNA/RNA non-specific endonuclease
Endonuc_BglI PF14562 Domain 4 6 284.00 48 96.16 Changed Restriction endonuclease BglI
Endonuc_Holl PF10107 Family 10 153 127.40 36 80.85 Changed Endonuclease related to archaeal Holliday junction resolvase
Endonuc_subdom PF09062 Domain 2 3 95.70 44 6.42 Changed PI-PfuI Endonuclease subdomain
Endopep_inhib PF16800 Domain 13 112 143.50 19 56.42 Changed IseA DL-endopeptidase inhibitor
Endostatin PF06482 Domain 38 1023 178.30 27 25.91 Changed Collagenase NC10 and Endostatin
Endosulfine PF04667 Family 32 1606 80.80 32 55.56 Changed cAMP-regulated phosphoprotein/endosulfine conserved region
Endothelin PF00322 Repeat 6 317 28.60 78 15.69 Changed Endothelin family
Endotoxin_C PF03944 Domain 80 23 124.90 13 12.68 Changed delta endotoxin
Endotoxin_C2 PF18449 Domain 57 395 62.60 36 26.87 New Delta endotoxin
Endotoxin_M PF00555 Domain 36 2 206.50 17 32.04 Changed delta endotoxin
Endotoxin_mid PF09131 Domain 3 4 139.00 26 35.30 Changed Bacillus thuringiensis delta-Endotoxin, middle domain
Endotoxin_N PF03945 Domain 5 166 196.70 16 33.75 Changed delta endotoxin, N-terminal domain
EndoU_bacteria PF14436 Family 54 454 123.30 17 19.41 Changed Bacterial EndoU nuclease
End_beta_barrel PF12195 Domain 3 4 82.50 37 11.23 Changed Beta barrel domain of bacteriophage endosialidase
End_beta_propel PF12217 Domain 3 12 423.90 63 49.38 Changed Catalytic beta propeller domain of bacteriophage endosialidase
End_N_terminal PF12218 Domain 4 21 60.00 49 7.14 Changed N terminal extension of bacteriophage endosialidase
End_tail_spike PF12219 Domain 5 17 130.50 45 14.61 Changed Catalytic domain of bacteriophage endosialidase
Engrail_1_C_sig PF10525 Domain 20 402 30.50 63 9.93 Changed Engrailed homeobox C-terminal signature domain
Enkurin PF13864 Family 135 795 96.60 27 29.92 Changed Calmodulin-binding
Eno-Rase_FAD_bd PF07055 Family 123 1101 63.90 47 16.17 Changed Enoyl reductase FAD binding domain
Eno-Rase_NADH_b PF12242 Family 131 1094 78.90 58 19.91 Changed NAD(P)H binding domain of trans-2-enoyl-CoA reductase
ENOD40 PF08247 Family 4 1 12.00 100 100.00 Changed ENOD40 protein
ENOD93 PF03386 Family 11 426 73.00 59 65.37 Changed Early nodulin 93 ENOD93 protein
Enolase_C PF00113 Domain 9 11440 275.10 51 65.91 Changed Enolase, C-terminal TIM barrel domain
Enolase_like_N PF18374 Domain 78 806 51.50 57 15.70 New Enolase N-terminal domain-like
Enolase_N PF03952 Domain 774 10885 128.40 58 30.22 Changed Enolase, N-terminal domain
Enoyl_reductase PF12241 Family 97 1114 233.80 54 59.29 Changed Trans-2-enoyl-CoA reductase catalytic region
ENT PF03735 Family 47 1250 66.10 43 11.49 Changed ENT domain
EntA_Immun PF08951 Family 62 459 71.10 18 53.72 Changed Enterocin A Immunity
Entericidin PF08085 Family 77 1357 19.80 47 42.19 Changed Entericidin EcnA/B family
Enterotoxin_a PF01375 Domain 6 416 190.90 20 34.70 Changed Heat-labile enterotoxin alpha chain
Enterotoxin_b PF01376 Domain 1 2 102.00 98 82.26 Changed Heat-labile enterotoxin beta chain
Enterotoxin_HS1 PF08090 Family 2 0 0.00 0 0.00 Changed Heat stable E.coli enterotoxin 1
Enterotoxin_ST PF02048 Family 6 3 52.00 27 67.83 Changed Heat-stable enterotoxin ST
ENTH PF01417 Domain 63 3635 120.10 39 21.82 Changed ENTH domain
Env-gp36 PF09590 Family 5 0 0.00 0 0.00 Changed Lentivirus surface glycoprotein
EnY2 PF10163 Family 105 859 78.80 36 54.50 Changed Transcription factor e(y)2
EOS1 PF12326 Family 31 456 119.80 27 32.19 Changed N-glycosylation protein
EP400_N PF15790 Family 5 240 417.10 68 18.29 Changed E1A-binding protein p400, N-terminal
EpCAM_N PF18635 Domain 12 47 32.80 73 10.11 New Epithelial cell adhesion molecule N-terminal domain
Ependymin PF00811 Family 50 348 123.10 28 56.64 Changed Ependymin
EPF PF17181 Family 48 1058 60.10 40 47.81 Changed Epidermal patterning factor proteins
EphA2_TM PF14575 Domain 181 2290 74.10 42 8.71 Changed Ephrin type-A receptor 2 transmembrane domain
Ephrin PF00812 Domain 43 1326 125.90 36 45.82 Changed Ephrin
Ephrin_lbd PF01404 Domain 67 2197 168.60 50 19.45 Changed Ephrin receptor ligand binding domain
Ephrin_rec_like PF07699 Family 29 6986 47.20 30 7.48 Changed Putative ephrin-receptor like
Epiglycanin_C PF14654 Domain 6 46 95.60 58 14.00 Changed Mucin, catalytic, TM and cytoplasmic tail region
Epiglycanin_TR PF05647 Repeat 15 260 59.60 48 89.80 Changed Tandem-repeating region of mucin, epiglycanin-like
Epimerase PF01370 Family 96 69875 222.10 18 66.51 Changed NAD dependent epimerase/dehydratase family
Epimerase_2 PF02350 Family 94 7096 331.60 30 87.33 Changed UDP-N-acetylglucosamine 2-epimerase
EPL1 PF10513 Family 117 3171 167.80 20 17.20 Changed Enhancer of polycomb-like
EpmC PF04315 Family 41 607 157.70 49 83.97 Changed Elongation factor P hydroxylase
EPOP PF15223 Family 8 131 288.90 46 48.47 Changed Elongin BC and Polycomb repressive complex 2-associated protein
EpoR_lig-bind PF09067 Domain 12 723 98.20 31 19.40 Changed Erythropoietin receptor, ligand binding
EPO_TPO PF00758 Domain 13 208 147.60 35 58.58 Changed Erythropoietin/thrombopoietin
EppA_BapA PF07268 Family 2 2 137.00 61 79.88 Changed Exported protein precursor (EppA/BapA)
EpsG PF14897 Family 65 1251 322.40 15 88.74 Changed EpsG family
Epsilon_antitox PF08998 Domain 2 23 83.20 60 87.35 Changed Bacterial epsilon antitoxin
EPSP_synthase PF00275 Family 20 18714 392.50 25 84.78 Changed EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
EptA_B_N PF08019 Domain 153 1382 149.70 21 27.64 Changed Phosphoethanolamine transferase EptA/EptB
EPTP PF03736 Repeat 224 4033 44.60 24 21.58 Changed EPTP domain
EpuA PF11772 Family 35 524 45.60 35 50.58 Changed DNA-directed RNA polymerase subunit beta
EPV_E5 PF08135 Family 1 4 41.80 52 94.35 Changed Major transforming protein E5 family
Equine_IAV_S2 PF06502 Family 2 1 42.00 100 33.87 Changed Equine infectious anaemia virus S2 protein
ER PF01133 Family 49 675 92.70 49 63.75 Changed Enhancer of rudimentary
ER-remodelling PF14755 Domain 5 18 92.20 31 25.00 Changed Intracellular membrane remodeller
ERAP1_C PF11838 Domain 781 8355 294.30 18 35.37 Changed ERAP1-like C-terminal domain
ERbeta_N PF12497 Family 18 179 111.10 56 21.04 Changed Estrogen receptor beta
ERCC3_RAD25_C PF16203 Domain 40 3002 206.70 41 32.34 Changed ERCC3/RAD25/XPB C-terminal helicase
ERCC4 PF02732 Domain 154 3763 145.80 21 20.63 Changed ERCC4 domain
ERF PF04404 Family 28 723 149.20 19 63.18 Changed ERF superfamily
eRF1_1 PF03463 Domain 269 3198 124.00 32 30.15 Changed eRF1 domain 1
eRF1_2 PF03464 Domain 21 3206 129.60 32 31.23 Changed eRF1 domain 2
eRF1_3 PF03465 Domain 34 3449 117.00 33 28.68 Changed eRF1 domain 3
Erf4 PF10256 Domain 124 1377 113.10 29 38.85 Changed Golgin subfamily A member 7/ERF4 family
Erg28 PF03694 Family 128 870 110.80 33 73.30 Changed Erg28 like protein
ERG2_Sigma1R PF04622 Family 110 870 192.50 36 81.77 Changed ERG2 and Sigma1 receptor like protein
ERG4_ERG24 PF01222 Family 5 2826 381.20 31 84.65 Changed Ergosterol biosynthesis ERG4/ERG24 family
ERGIC_N PF13850 Domain 319 2902 88.70 32 21.85 Changed Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
ERK-JNK_inhib PF15002 Family 17 284 175.70 36 71.96 Changed ERK and JNK pathways, inhibitor
ERM PF00769 Coiled-coil 70 1298 226.20 34 40.14 Changed Ezrin/radixin/moesin family
ErmC PF06308 Family 2 3 29.70 98 100.00 Changed 23S rRNA methylastransferase leader peptide (ErmCL)
ERO1 PF04137 Family 166 1562 340.30 36 72.73 Changed Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
ERp29 PF07749 Domain 160 985 91.80 30 25.66 Changed Endoplasmic reticulum protein ERp29, C-terminal domain
ERp29_N PF07912 Domain 3 210 117.30 47 43.52 Changed ERp29, N-terminal domain
Erp_C PF06780 Family 4 8 134.80 33 38.28 Changed Erp protein C-terminus
Erv26 PF04148 Family 76 774 188.20 37 82.62 Changed Transmembrane adaptor Erv26
Erythro-docking PF09277 Domain 2 19 53.70 43 2.97 Changed Erythronolide synthase, docking
Erythrovirus_X PF06795 Family 1 1 81.00 100 100.00 Changed Erythrovirus X protein
Erythro_esteras PF05139 Family 175 2134 325.80 23 72.91 Changed Erythromycin esterase
Eryth_link_C PF16915 Domain 13 0 0.00 0 0.00 Changed Annelid erythrocruorin linker subunit C-terminus
Ery_res_leader1 PF08051 Family 1 2 15.00 100 100.00 Changed Erythromycin resistance leader peptide
Ery_res_leader2 PF08057 Family 1 0 0.00 0 0.00 Changed Erythromycin resistance leader peptide
ER_lumen_recept PF00810 Family 245 2580 138.40 42 55.87 Changed ER lumen protein retaining receptor
Es2 PF09751 Family 62 1200 322.50 25 74.88 Changed Nuclear protein Es2
ESAG1 PF03238 Family 11 13 228.80 56 70.05 Changed ESAG protein
ESCRT-II PF05871 Family 150 1123 132.90 36 59.75 Changed ESCRT-II complex subunit
ESF1 PF18209 Domain 15 22 25.70 42 25.85 New Embryo surrounding factor 1
ESM4 PF15952 Family 14 176 157.50 28 95.45 Changed Enhancer of split M4 family
ESP PF16590 Family 13 31 78.90 32 72.85 Changed Exocrine gland-secreting peptide
EspA PF03433 Family 7 65 156.60 27 91.88 Changed EspA-like secreted protein
EspB PF05802 Family 7 64 155.20 19 82.70 Changed Enterobacterial EspB protein
EspB_PE PF18625 Domain 28 85 75.70 38 15.57 New ESX-1 secreted protein B PE domain
EspF PF04806 Repeat 3 13 42.70 67 30.88 Changed EspF protein repeat
EspG PF06872 Family 4 5 387.80 36 98.13 Changed EspG protein
ESPR PF13018 Domain 145 1436 23.70 42 1.21 Changed Extended Signal Peptide of Type V secretion system
ESR1_C PF12743 Domain 17 114 43.80 59 8.33 Changed Oestrogen-type nuclear receptor final C-terminal
EssA PF10661 Family 4 44 134.20 20 85.02 Changed WXG100 protein secretion system (Wss), protein EssA
ESSS PF10183 Family 17 661 107.70 25 75.18 Changed ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
EST1 PF10374 Family 127 1638 121.60 24 12.62 Changed Telomerase activating protein Est1
EST1_DNA_bind PF10373 Family 51 2462 248.00 18 28.22 Changed Est1 DNA/RNA binding domain
EstA_Ig_like PF18435 Domain 82 287 128.80 19 26.20 New Esterase Ig-like N-terminal domain
Esterase PF00756 Domain 20 17437 232.80 16 69.87 Changed Putative esterase
Esterase_phd PF10503 Family 2 4149 180.50 22 49.97 Changed Esterase PHB depolymerase
ESX-1_EspG PF14011 Family 133 1353 239.10 20 90.41 Changed EspG family
ET PF01684 Family 55 540 77.40 34 73.83 Changed ET module
ETAA1 PF15350 Family 18 197 466.10 29 89.43 Changed Ewing's tumour-associated antigen 1 homologue
ETC_C1_NDUFA4 PF04800 Family 159 2114 94.90 40 61.43 Changed ETC complex I subunit conserved region
ETC_C1_NDUFA5 PF04716 Family 125 997 68.50 37 37.06 Changed ETC complex I subunit conserved region
ETF PF01012 Domain 129 18055 178.50 22 60.80 Changed Electron transfer flavoprotein domain
ETF_alpha PF00766 Domain 511 9223 83.40 57 25.03 Changed Electron transfer flavoprotein FAD-binding domain
ETF_QO PF05187 Family 44 3878 99.80 51 19.92 Changed Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S
EthD PF07110 Domain 56 2971 88.60 18 56.48 Changed EthD domain
ETM PF17577 Family 1 10 107.50 56 92.27 Changed ECORI-T site
Etmic-2 PF06670 Family 2 13 187.60 31 72.31 Changed Microneme protein Etmic-2
ETRAMP PF09716 Family 42 337 88.30 25 51.37 Changed Malarial early transcribed membrane protein (ETRAMP)
Ets PF00178 Domain 151 5546 79.50 51 19.45 Changed Ets-domain
ETS_PEA3_N PF04621 Family 35 600 266.50 53 68.02 Changed PEA3 subfamily ETS-domain transcription factor N terminal domain
ETX_MTX2 PF03318 Family 15 354 190.90 14 56.27 Changed Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2
Euplotes_phero PF05842 Family 6 0 0.00 0 0.00 Changed Euplotes octocarinatus mating pheromone protein
EURL PF06937 Family 4 149 246.20 65 94.28 Changed EURL protein
EutA PF06277 Family 15 441 443.90 36 96.20 Changed Ethanolamine utilisation protein EutA
EutB PF06751 Family 114 1435 425.80 59 91.96 Changed Ethanolamine ammonia lyase large subunit (EutB)
EutC PF05985 Family 176 1406 231.20 42 80.37 Changed Ethanolamine ammonia-lyase light chain (EutC)
EutH PF04346 Family 57 466 353.70 42 93.87 Changed Ethanolamine utilisation protein, EutH
EutK_C PF16365 Domain 2 26 53.80 68 34.28 Changed Ethanolamine utilization protein EutK C-terminus
EutN_CcmL PF03319 Domain 194 1434 82.00 38 88.97 Changed Ethanolamine utilisation protein EutN/carboxysome
EutQ PF06249 Domain 4 770 114.60 26 73.78 Changed Ethanolamine utilisation protein EutQ
EVC2_like PF12297 Family 16 151 359.90 43 34.19 Changed Ellis van Creveld protein 2 like protein
EVE PF01878 Domain 136 3875 138.80 34 72.51 Changed EVE domain
Evf PF18270 Domain 5 32 232.60 37 81.20 New Virulence factor Evf
EVI2A PF05399 Family 11 105 207.20 43 86.57 Changed Ectropic viral integration site 2A protein (EVI2A)
Evr1_Alr PF04777 Family 333 2745 95.20 30 27.21 Changed Erv1 / Alr family
ExbD PF02472 Family 45 14436 133.20 22 88.90 Changed Biopolymer transport protein ExbD/TolR
Exc PF07825 Domain 2 82 73.00 30 80.86 Changed Excisionase-like protein
Excalibur PF05901 Domain 157 1804 37.90 38 19.02 Changed Excalibur calcium-binding domain
Exo5 PF09810 Family 69 1228 217.90 20 66.26 Changed Exonuclease V - a 5' deoxyribonuclease
Exo70 PF03081 Family 271 3612 324.40 23 56.65 Changed Exo70 exocyst complex subunit
Exo84_C PF16528 Domain 31 1250 199.50 26 27.84 Changed Exocyst component 84 C-terminal
ExoD PF06055 Family 155 1363 178.30 26 87.12 Changed Exopolysaccharide synthesis, ExoD
Exog_C PF18026 Domain 14 116 48.90 61 14.89 New Endo/exonuclease (EXOG) C-terminal domain
Exonuc_VIII PF06630 Family 2 39 157.10 31 20.91 Changed Enterobacterial exodeoxyribonuclease VIII
Exonuc_VII_L PF02601 Family 542 8306 238.40 27 67.53 Changed Exonuclease VII, large subunit
Exonuc_VII_S PF02609 Family 861 6642 51.80 35 64.15 Changed Exonuclease VII small subunit
Exonuc_V_gamma PF04257 Family 59 2153 636.00 24 59.85 Changed Exodeoxyribonuclease V, gamma subunit
Exonuc_X-T_C PF08411 Family 130 1155 258.10 34 55.03 Changed Exonuclease C-terminal
Exop_C PF18559 Domain 54 596 150.60 23 18.97 New Galactose-binding domain-like
EXOSC1 PF10447 Domain 11 1109 56.80 38 27.66 Changed Exosome component EXOSC1/CSL4
Exosortase_EpsH PF09721 Family 188 2177 233.50 17 66.67 Changed Transmembrane exosortase (Exosortase_EpsH)
Exostosin PF03016 Family 32 6076 272.50 22 52.34 Changed Exostosin family
Exotox-A_bind PF09101 Domain 2 7 167.30 24 22.77 Changed Exotoxin A binding
Exotox-A_cataly PF09009 Domain 4 8 147.00 28 36.52 Changed Exotoxin A catalytic
Exotox-A_target PF09102 Domain 2 3 139.00 60 21.68 Changed Exotoxin A, targeting
Exo_endo_phos PF03372 Domain 320 42099 267.30 12 59.90 Changed Endonuclease/Exonuclease/phosphatase family
Exo_endo_phos_2 PF14529 Domain 71 5180 116.40 18 17.86 Changed Endonuclease-reverse transcriptase
EXS PF03124 Family 332 3087 296.80 27 50.03 Changed EXS family
ExsD PF16806 Domain 4 19 242.80 26 82.35 Changed Antiactivator protein ExsD
Extensin-like_C PF06904 Family 88 1533 169.20 33 61.92 Changed Extensin-like protein C-terminus
Extensin_1 PF02095 Repeat 13 740 9.50 76 77.99 Changed Extensin-like protein repeat
Extensin_2 PF04554 Family 14 1583 49.30 70 56.46 Changed Extensin-like region
Ezh2_MCSS PF18600 Domain 23 108 52.30 53 4.50 New MCSS domain
EZH2_N PF18601 Domain 20 109 77.30 56 6.57 New EZH2 N-terminal domain
EZH2_WD-Binding PF11616 Family 12 353 29.90 70 4.51 Changed WD repeat binding protein EZH2
EzrA PF06160 Coiled-coil 88 738 533.70 24 95.98 Changed Septation ring formation regulator, EzrA
E_Pc_C PF06752 Family 18 328 218.90 54 29.14 Changed Enhancer of Polycomb C-terminus
E_raikovi_mat PF06360 Family 6 0 0.00 0 0.00 Changed Euplotes raikovi mating pheromone
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