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Browse Pfam families

New Top twenty Numbers A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
ID Accession Type Number of sequences Average length Average %id Average coverage Has 3D Change status Description
Seed Full
E1-E2_ATPase PF00122 Family 78 114833 223.00 26 27.62 Changed E1-E2 ATPase
E1-N PF14463 Family 2 7 150.30 31 32.92 Changed E1 N-terminal domain
E1_4HB PF16191 Domain 279 991 69.90 39 6.73 New Ubiquitin-activating enzyme E1 four-helix bundle
E1_DerP2_DerF2 PF02221 Domain 92 1740 125.70 19 72.74 Changed ML domain
E1_dh PF00676 Family 14 41655 302.00 28 50.44 Changed Dehydrogenase E1 component
E1_FCCH PF16190 Domain 176 1005 71.10 47 6.87 New Ubiquitin-activating enzyme E1 FCCH domain
E1_UFD PF09358 Domain 183 1008 91.00 37 9.30 Changed Ubiquitin fold domain
E2 PF08199 Family 1 7 31.40 89 94.02 Changed Bacteriophage E2-like protein
E2F_CC-MB PF16421 Domain 169 954 96.60 38 25.71 New E2F transcription factor CC-MB domain
E2F_TDP PF02319 Domain 210 2325 71.30 40 19.86 Changed E2F/DP family winged-helix DNA-binding domain
E2R135 PF11570 Coiled-coil 2 248 127.00 62 28.01 Changed Coiled-coil receptor-binding R-domain of colicin E2
E2_bind PF08825 Domain 152 512 84.00 36 19.29 Changed E2 binding domain
E3_binding PF02817 Family 1023 44496 35.60 43 8.23 Changed e3 binding domain
E3_UbLigase_EDD PF11547 Family 10 155 51.50 84 2.05 Changed E3 ubiquitin ligase EDD
E3_UbLigase_R4 PF13764 Family 33 336 593.30 35 20.37 Changed E3 ubiquitin-protein ligase UBR4
E6 PF00518 Family 12 1357 108.50 51 74.16 Changed Early Protein (E6)
E7 PF00527 Family 9 966 89.90 43 92.11 Changed E7 protein, Early protein
EABR PF12180 Domain 12 152 33.80 52 8.16 Changed TSG101 and ALIX binding domain of CEP55
Ead_Ea22 PF13935 Family 41 3868 134.40 32 67.25 Changed Ead/Ea22-like protein
EAF PF09816 Domain 111 564 102.60 29 29.42 Changed RNA polymerase II transcription elongation factor
Eaf7 PF07904 Family 61 458 106.40 27 39.82 Changed Chromatin modification-related protein EAF7
EAGR_box PF16713 Domain 22 269 34.00 45 10.19 New Enriched in aromatic and glycine Residues box
EAL PF00563 Domain 76 108082 226.90 27 38.15 Changed EAL domain
EamA PF00892 Family 98 249312 135.40 16 81.08 Changed EamA-like transporter family
EAP30 PF04157 Family 247 1209 219.20 25 58.40 Changed EAP30/Vps36 family
Eapp_C PF10238 Family 67 278 129.60 39 50.43 Changed E2F-associated phosphoprotein
EAR PF07897 Family 30 154 38.20 50 10.61 Changed Ethylene-responsive binding factor-associated repression
EAV_GP5 PF15981 Family 1 429 57.90 88 26.78 New Envelope glycoprotein GP 5 of equine arteritis virus
EAV_GS PF01309 Family 1 125 196.00 95 86.34 Changed Equine arteritis virus small envelope glycoprotein
EB PF01683 Family 228 1467 54.50 25 19.90 Changed EB module
EB1 PF03271 Family 171 991 41.90 52 14.17 Changed EB1-like C-terminal motif
EB1_binding PF05937 Family 6 74 168.10 79 6.47 Changed EB-1 Binding Domain
EBA-175_VI PF11556 Family 11 213 78.30 54 7.26 Changed Erythrocyte binding antigen 175
Ebola_NP PF05505 Family 2 143 429.40 82 98.62 Changed Ebola nucleoprotein
EBP PF05241 Family 178 752 181.70 30 74.42 Changed Emopamil binding protein
Ebp2 PF05890 Family 139 678 249.50 31 75.42 Changed Eukaryotic rRNA processing protein EBP2
EBP50_C PF09007 Domain 35 270 91.70 36 36.60 Changed EBP50, C-terminal
EBV-NA1 PF02905 Domain 2 153 92.80 89 60.86 Changed Epstein Barr virus nuclear antigen-1, DNA-binding domain
EBV-NA3 PF05009 Family 3 169 239.80 64 40.29 Changed Epstein-Barr virus nuclear antigen 3 (EBNA-3)
EB_dh PF09459 Domain 49 389 234.70 18 66.93 Changed Ethylbenzene dehydrogenase
EccE PF11203 Family 55 6958 91.60 41 21.09 Changed Putative type VII ESX secretion system translocon, EccE
ECF-ribofla_trS PF07155 Family 49 10204 163.70 32 89.99 Changed ECF-type riboflavin transporter, S component
ECH_1 PF00378 Domain 9 123859 228.70 26 67.98 Changed Enoyl-CoA hydratase/isomerase
ECH_2 PF16113 Domain 301 7483 308.00 37 86.74 New Enoyl-CoA hydratase/isomerase
ECIST_C PF14784 Domain 43 160 118.80 38 31.38 Changed C-terminal domain of the ECSIT protein
EcKinase PF02958 Family 51 2560 232.90 18 60.46 Changed Ecdysteroid kinase
Ecl1 PF12855 Family 22 355 41.90 37 20.70 Changed Life-span regulatory factor
Eclosion PF04736 Family 10 63 59.40 53 65.74 Changed Eclosion hormone
ECM1 PF05782 Family 12 100 348.80 41 93.12 Changed Extracellular matrix protein 1 (ECM1)
ECM11 PF15463 Family 69 185 133.70 28 27.64 Changed Extracellular mutant protein 11
Ecm29 PF13001 Family 124 579 430.40 25 27.36 Changed Proteasome stabiliser
Ecm33 PF12454 Family 17 99 39.90 44 9.99 Changed GPI-anchored cell wall organization protein
Eco57I PF07669 Domain 17 2176 108.70 27 13.40 Changed Eco57I restriction-modification methylase
EcoEI_R_C PF08463 Family 231 3878 155.80 24 17.13 Changed EcoEI R protein C-terminal
EcoR124_C PF12008 Domain 181 6995 262.20 48 28.27 Changed Type I restriction and modification enzyme - subunit R C terminal
EcoRI PF02963 Domain 8 147 188.20 54 89.25 Changed Restriction endonuclease EcoRI
EcoRII-C PF09019 Domain 9 1182 166.50 56 49.32 Changed EcoRII C terminal
EcoRII-N PF09217 Domain 7 432 144.50 52 37.88 Changed Restriction endonuclease EcoRII, N-terminal
EcoRI_methylase PF13651 Family 23 445 243.80 37 91.33 Changed Adenine-specific methyltransferase EcoRI
Ecotin PF03974 Family 57 3758 122.60 78 75.46 Changed Ecotin
ECR1_N PF14382 Domain 252 1086 38.50 35 14.35 Changed Exosome complex exonuclease RRP4 N-terminal region
EcsB PF05975 Family 70 8232 325.50 42 94.93 Changed Bacterial ABC transporter protein EcsB
EcsC PF12787 Family 90 3046 239.50 22 78.31 Changed EcsC protein family
ECSCR PF15820 Family 2 52 96.10 74 42.38 New Endothelial cell-specific chemotaxis regulator
ECSIT PF06239 Family 19 173 204.60 40 51.84 Changed Evolutionarily conserved signalling intermediate in Toll pathway
Ectatomin PF06457 Domain 2 2 34.00 47 95.77 Changed Ectatomin
ecTbetaR2 PF08917 Domain 20 137 105.00 55 20.82 Changed Transforming growth factor beta receptor 2 ectodomain
Ectoine_synth PF06339 Family 34 1064 123.80 50 95.56 Changed Ectoine synthase
Edc3_linker PF16598 Family 7 78 91.60 70 18.61 New Linker region of enhancer of mRNA-decapping protein 3
EDR1 PF14381 Family 78 747 193.00 30 24.57 Changed Ethylene-responsive protein kinase Le-CTR1
EELM2 PF15863 Domain 8 81 156.40 49 31.03 New Extended EGL-27 and MTA1 homology domain
EF-1_beta_acid PF10587 Domain 77 823 27.40 62 10.08 Changed Eukaryotic elongation factor 1 beta central acidic region
EF-hand_1 PF00036 Domain 572 5613 28.30 32 11.67 Changed EF hand
EF-hand_10 PF14788 Domain 10 314 49.80 47 6.71 Changed EF hand
EF-hand_11 PF08976 Domain 2 202 92.60 27 16.02 Changed EF-hand domain
EF-hand_2 PF09068 Domain 68 900 119.80 40 11.13 Changed EF hand
EF-hand_3 PF09069 Domain 24 859 90.20 48 8.11 Changed EF-hand
EF-hand_4 PF12763 Family 13 4218 95.20 31 17.07 Changed Cytoskeletal-regulatory complex EF hand
EF-hand_5 PF13202 Domain 109 14563 23.50 30 9.15 Changed EF hand
EF-hand_6 PF13405 Domain 621 3489 31.70 33 11.06 Changed EF-hand domain
EF-hand_7 PF13499 Domain 103 34716 68.70 27 23.11 Changed EF-hand domain pair
EF-hand_8 PF13833 Domain 40 13981 49.40 26 15.16 Changed EF-hand domain pair
EF-hand_9 PF14658 Domain 7 138 65.30 35 16.55 Changed EF-hand domain
EF-hand_like PF09279 Domain 46 2037 83.40 24 8.44 Changed Phosphoinositide-specific phospholipase C, efhand-like
EF1G PF00647 Domain 110 1111 99.90 48 27.12 Changed Elongation factor 1 gamma, conserved domain
EF1_GNE PF00736 Domain 192 1556 84.60 45 37.72 Changed EF-1 guanine nucleotide exchange domain
efb-c PF12199 Domain 2 8073 65.00 71 47.57 Changed Extracellular fibrinogen binding protein C terminal
EFF-AFF PF14884 Family 4 67 363.00 28 90.12 Changed Type I membrane glycoproteins cell-cell fusogen
Effector_1 PF04518 Family 8 652 380.60 32 53.52 Changed Effector from type III secretion system
EFG_C PF00679 Domain 129 70189 87.90 30 13.59 Changed Elongation factor G C-terminus
EFG_II PF14492 Domain 86 37485 72.60 43 10.67 Changed Elongation Factor G, domain II
EFG_IV PF03764 Domain 67 31463 118.80 42 17.44 Changed Elongation factor G, domain IV
EFhand_Ca_insen PF08726 Domain 18 993 67.80 44 6.04 Changed Ca2+ insensitive EF hand
EFP PF01132 Domain 889 23549 54.30 37 29.03 Changed Elongation factor P (EF-P) OB domain
EFP_N PF08207 Domain 180 23620 57.70 41 30.90 Changed Elongation factor P (EF-P) KOW-like domain
efThoc1 PF11957 Family 49 642 421.60 26 69.24 Changed THO complex subunit 1 transcription elongation factor
EFTUD2 PF16004 Family 156 583 110.30 43 11.84 New 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
EF_assoc_1 PF08355 Family 101 726 72.30 39 11.52 Changed EF hand associated
EF_assoc_2 PF08356 Family 115 735 87.20 44 13.88 Changed EF hand associated
EF_TS PF00889 Family 104 20021 201.10 41 70.67 Changed Elongation factor TS
EGF PF00008 Domain 67 35435 31.80 40 10.23 Changed EGF-like domain
EGF_2 PF07974 Domain 50 3615 30.60 40 4.36 Changed EGF-like domain
EGF_3 PF12947 Domain 136 5091 37.40 37 5.64 Changed EGF domain
EGF_alliinase PF04863 Domain 20 121 54.30 61 12.55 Changed Alliinase EGF-like domain
EGF_CA PF07645 Domain 18 35029 41.60 35 12.21 Changed Calcium-binding EGF domain
EGF_MSP1_1 PF12946 Domain 9 1743 36.90 69 5.02 Changed MSP1 EGF domain 1
Egg_lysin PF01303 Domain 24 86 88.10 47 82.76 Changed Egg lysin (Sperm-lysin)
EGL-1 PF11430 Family 10 14 19.60 65 18.99 Changed Programmed cell death activator EGL-1
Ehbp PF10622 Family 11 33 81.90 58 90.07 Changed Energy-converting hydrogenase B subunit P (EhbP)
EHD_N PF16880 Family 87 815 32.60 50 5.88 New N-terminal EH-domain containing protein
EHN PF06441 Family 614 2306 108.60 36 26.64 Changed Epoxide hydrolase N terminus
Ehrlichia_rpt PF09528 Repeat 2 71 235.40 44 111.87 Changed Ehrlichia tandem repeat (Ehrlichia_rpt)
EH_Signature PF15611 Domain 26 397 384.80 24 77.66 Changed EH_Signature domain
EI24 PF07264 Family 326 7033 214.70 36 82.54 Changed Etoposide-induced protein 2.4 (EI24)
EIAV_GP90 PF00971 Family 3 1454 270.90 65 81.15 Changed EIAV coat protein, gp90
EIAV_Rev PF11129 Family 2 362 128.60 87 95.68 Changed Rev protein of equine infectious anaemia virus
eIF-1a PF01176 Domain 431 21549 63.80 64 80.97 Changed Translation initiation factor 1A / IF-1
eIF-3c_N PF05470 Family 7 967 419.00 29 66.59 Changed Eukaryotic translation initiation factor 3 subunit 8 N-terminus
eIF-3_zeta PF05091 Family 105 729 444.00 39 89.53 Changed Eukaryotic translation initiation factor 3 subunit 7 (eIF-3)
eIF-4B PF06273 Family 9 238 255.50 26 79.08 Changed Plant specific eukaryotic initiation factor 4B
eIF-5a PF01287 Domain 53 1378 67.20 39 37.96 Changed Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
eIF-5_eIF-2B PF01873 Family 203 1996 115.30 35 37.05 Changed Domain found in IF2B/IF5
eIF-6 PF01912 Family 152 1083 189.20 51 81.61 Changed eIF-6 family
eIF2A PF08662 Family 19 2626 169.60 19 29.51 Changed Eukaryotic translation initiation factor eIF2A
eIF2_C PF09173 Domain 116 1095 88.30 50 19.29 Changed Initiation factor eIF2 gamma, C terminal
eIF3g PF12353 Family 115 704 117.90 34 38.42 Changed Eukaryotic translation initiation factor 3 subunit G
eIF3_N PF09440 Domain 118 586 129.00 37 30.22 Changed eIF3 subunit 6 N terminal domain
eIF3_p135 PF12807 Family 161 941 161.20 25 12.02 Changed Translation initiation factor eIF3 subunit 135
eIF3_subunit PF08597 Family 166 654 233.90 26 93.93 Changed Translation initiation factor eIF3 subunit
EIF4E-T PF10477 Family 9 311 431.00 24 65.15 Changed Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E
EIF_2_alpha PF07541 Family 196 1053 113.40 33 37.88 Changed Eukaryotic translation initiation factor 2 alpha subunit
eIF_4EBP PF05456 Family 46 315 106.20 45 76.54 Changed Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
eIF_4G1 PF12152 Domain 52 389 71.10 43 5.67 Changed Eukaryotic translation initiation factor 4G1
EII-GUT PF03608 Family 50 4799 164.40 70 89.95 Changed PTS system enzyme II sorbitol-specific factor
EII-Sor PF03609 Family 301 23301 231.60 33 88.07 Changed PTS system sorbose-specific iic component
EIIA-man PF03610 Family 27 40814 113.30 22 38.25 Changed PTS system fructose IIA component
EIIBC-GUT_C PF07663 Family 25 4773 92.70 81 29.64 Changed Sorbitol phosphotransferase enzyme II C-terminus
EIIBC-GUT_N PF03612 Family 66 5257 159.40 61 52.35 Changed Sorbitol phosphotransferase enzyme II N-terminus
EIIC-GAT PF03611 Family 152 30595 385.80 29 87.77 Changed PTS system sugar-specific permease component
EIID-AGA PF03613 Family 300 23809 262.40 37 94.91 Changed PTS system mannose/fructose/sorbose family IID component
EIN3 PF04873 Family 10 363 221.90 60 43.90 Changed Ethylene insensitive 3
EKLF_TAD1 PF16832 Domain 2 39 25.70 83 7.48 New Erythroid krueppel-like transcription factor, transactivation 1
EKLF_TAD2 PF16833 Domain 12 41 26.80 67 7.69 New Erythroid krueppel-like transcription factor, transactivation 2
EKR PF10371 Domain 147 6765 55.40 51 4.75 Changed Domain of unknown function
ELF PF03317 Family 1 40 189.90 71 82.74 Changed ELF protein
Elf-1_N PF12310 Family 19 259 92.60 43 17.49 Changed Transcription factor protein N terminal
Elf1 PF05129 Domain 152 746 76.50 42 61.64 Changed Transcription elongation factor Elf1 like
ELFV_dehydrog PF00208 Domain 98 23505 222.20 37 52.77 Changed Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
ELFV_dehydrog_N PF02812 Domain 431 22196 125.80 47 30.12 Changed Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
ELH PF02323 Family 4 27 114.20 39 88.77 Changed Egg-laying hormone precursor
Elicitin PF00964 Domain 69 809 88.30 26 47.71 Changed Elicitin
ELK PF03789 Domain 33 1914 22.00 71 10.98 Changed ELK domain
ELL PF10390 Family 38 443 236.00 32 40.39 Changed RNA polymerase II elongation factor ELL
ELM2 PF01448 Family 222 1513 55.50 30 7.88 Changed ELM2 domain
ELMO_CED12 PF04727 Family 234 1679 166.90 24 31.24 Changed ELMO/CED-12 family
ELO PF01151 Family 153 3399 227.10 27 78.72 Changed GNS1/SUR4 family
EloA-BP1 PF15870 Family 30 343 122.00 30 16.03 New ElonginA binding-protein 1
Elong-fact-P_C PF09285 Domain 500 23481 55.70 53 29.83 Changed Elongation factor P, C-terminal
Elongin_A PF06881 Family 123 542 103.00 27 22.36 Changed RNA polymerase II transcription factor SIII (Elongin) subunit A
Elong_Iki1 PF10483 Family 90 443 243.00 21 78.58 Changed Elongator subunit Iki1
ELP6 PF09807 Family 17 346 198.20 22 84.71 Changed Elongation complex protein 6
ELYS PF13934 Family 117 432 231.90 24 23.79 Changed Nuclear pore complex assembly
ELYS-bb PF16687 Domain 5 139 394.40 43 24.65 New beta-propeller of ELYS nucleoporin
EMA PF02488 Family 2 607 233.40 65 91.64 Changed Merozoite Antigen
Emaravirus_P4 PF16505 Family 2 63 270.20 70 97.74 New P4 movement protein of Emaravirus, and the 30K superfamily
EMG1 PF03587 Family 141 882 195.90 42 78.67 Changed EMG1/NEP1 methyltransferase
EMI PF07546 Domain 130 722 67.90 34 10.93 Changed EMI domain
EMP24_GP25L PF01105 Domain 215 4101 176.80 21 78.09 Changed emp24/gp25L/p24 family/GOLD
EMP70 PF02990 Family 361 2745 431.80 36 82.55 Changed Endomembrane protein 70
EmrE PF13536 Family 59 763 260.00 54 83.49 Changed Putative multidrug resistance efflux transporter
Enamelin PF15362 Family 16 284 723.60 60 93.07 Changed Enamelin
End3 PF12761 Family 47 253 175.90 39 48.58 Changed Actin cytoskeleton-regulatory complex protein END3
EndIII_4Fe-2S PF10576 Domain 517 19058 17.00 53 6.74 Changed Iron-sulfur binding domain of endonuclease III
Endomucin PF07010 Family 11 57 177.80 51 89.51 Changed Endomucin
Endonuc-BglII PF09195 Domain 9 177 166.50 21 82.52 Changed Restriction endonuclease BglII
Endonuc-BsobI PF09194 Domain 9 60 238.20 43 98.82 Changed Restriction endonuclease BsobI
Endonuc-dimeris PF09124 Domain 8 56 52.60 46 33.84 Changed T4 recombination endonuclease VII, dimerisation
Endonuc-EcoRV PF09233 Domain 9 101 205.40 42 87.20 Changed Restriction endonuclease EcoRV
Endonuc-FokI_C PF09254 Domain 6 51 176.50 33 33.39 Changed Restriction endonuclease FokI, C terminal
Endonuc-HincII PF09226 Domain 3 16 238.10 55 91.41 Changed Restriction endonuclease HincII
Endonuc-MspI PF09208 Domain 5 19 240.50 34 67.97 Changed Restriction endonuclease MspI
Endonuc-PvuII PF09225 Domain 4 39 148.40 59 79.21 Changed Restriction endonuclease PvuII
Endonuclease_1 PF04231 Family 14 5508 204.70 50 73.69 Changed Endonuclease I
Endonuclease_5 PF04493 Family 172 4454 192.40 63 85.12 Changed Endonuclease V
Endonuclease_7 PF02945 Domain 16 550 83.00 29 32.62 Changed Recombination endonuclease VII
Endonuclease_NS PF01223 Domain 58 7257 211.00 20 60.58 Changed DNA/RNA non-specific endonuclease
Endonuclea_NS_2 PF13930 Domain 21 6436 132.50 42 27.44 Changed DNA/RNA non-specific endonuclease
Endonuc_BglI PF14562 Domain 3 5 288.40 56 97.50 Changed Restriction endonuclease BglI
Endonuc_Holl PF10107 Family 10 817 133.00 78 85.51 Changed Endonuclease related to archaeal Holliday junction resolvase
Endonuc_subdom PF09062 Domain 2 5 86.40 67 4.96 Changed PI-PfuI Endonuclease subdomain
Endopep_inhib PF16800 Domain 15 203 148.20 29 47.08 New IseA DL-endopeptidase inhibitor
Endostatin PF06482 Domain 40 411 230.70 36 27.75 Changed Collagenase NC10 and Endostatin
Endosulfine PF04667 Family 32 899 81.60 31 56.40 Changed cAMP-regulated phosphoprotein/endosulfine conserved region
Endothelin PF00322 Repeat 7 249 28.40 74 17.22 Changed Endothelin family
Endotoxin_C PF03944 Domain 80 844 135.10 31 14.82 Changed delta endotoxin
Endotoxin_M PF00555 Domain 36 651 201.50 28 20.90 Changed delta endotoxin
Endotoxin_mid PF09131 Domain 3 109 189.90 71 33.12 Changed Bacillus thuringiensis delta-Endotoxin, middle domain
Endotoxin_N PF03945 Domain 5 984 205.20 27 23.91 Changed delta endotoxin, N-terminal domain
EndoU_bacteria PF14436 Family 56 938 118.40 22 19.06 Changed Bacterial EndoU nuclease
End_beta_barrel PF12195 Domain 3 151 82.50 88 8.82 Changed Beta barrel domain of bacteriophage endosialidase
End_beta_propel PF12217 Domain 3 160 415.60 88 46.05 Changed Catalytic beta propeller domain of bacteriophage endosialidase
End_N_terminal PF12218 Domain 5 149 66.00 81 7.18 Changed N terminal extension of bacteriophage endosialidase
End_tail_spike PF12219 Domain 5 156 147.70 88 16.24 Changed Catalytic domain of bacteriophage endosialidase
Engrail_1_C_sig PF10525 Domain 20 318 29.30 66 10.71 Changed Engrailed homeobox C-terminal signature domain
Enkurin PF13864 Family 142 508 97.00 26 32.63 Changed Calmodulin-binding
Eno-Rase_FAD_bd PF07055 Family 131 1712 63.90 52 16.21 Changed Enoyl reductase FAD binding domain
Eno-Rase_NADH_b PF12242 Family 44 1705 78.60 63 19.94 Changed NAD(P)H binding domain of trans-2-enoyl-CoA reductase
ENOD40 PF08247 Family 4 11 12.30 76 100.00 Changed ENOD40 protein
ENOD93 PF03386 Family 12 199 74.10 59 68.16 Changed Early nodulin 93 ENOD93 protein
Enolase_C PF00113 Domain 9 24383 271.70 57 67.23 Changed Enolase, C-terminal TIM barrel domain
Enolase_N PF03952 Domain 810 23100 127.90 63 30.53 Changed Enolase, N-terminal domain
Enoyl_reductase PF12241 Family 103 1717 234.60 57 59.40 Changed Trans-2-enoyl-CoA reductase catalytic region
ENT PF03735 Family 58 532 66.40 41 12.00 Changed ENT domain
EntA_Immun PF08951 Family 66 3346 71.70 18 58.63 Changed Enterocin A Immunity
Entericidin PF08085 Family 105 7766 20.90 64 44.90 Changed Entericidin EcnA/B family
Enterotoxin_a PF01375 Domain 6 554 224.80 46 57.57 Changed Heat-labile enterotoxin alpha chain
Enterotoxin_b PF01376 Domain 1 155 90.10 88 84.97 Changed Heat-labile enterotoxin beta chain
Enterotoxin_HS1 PF08090 Family 2 11 35.50 91 95.82 Changed Heat stable E.coli enterotoxin 1
Enterotoxin_ST PF02048 Family 6 62 47.80 61 72.73 Changed Heat-stable enterotoxin ST
ENTH PF01417 Domain 64 2023 120.10 38 23.16 Changed ENTH domain
Env-gp36 PF09590 Family 5 1139 233.30 65 86.41 Changed Lentivirus surface glycoprotein
EnY2 PF10163 Family 113 475 78.40 33 54.90 Changed Transcription factor e(y)2
EOS1 PF12326 Family 31 252 121.50 29 36.93 Changed N-glycosylation protein
EP400_N PF15790 Family 6 120 384.20 60 21.15 New E1A-binding protein p400, N-terminal
Ependymin PF00811 Family 51 283 123.30 27 55.05 Changed Ependymin
EphA2_TM PF14575 Domain 185 1355 79.30 36 8.69 Changed Ephrin type-A receptor 2 transmembrane domain
Ephrin PF00812 Domain 45 802 125.90 37 47.84 Changed Ephrin
Ephrin_lbd PF01404 Domain 69 1432 166.10 52 19.27 Changed Ephrin receptor ligand binding domain
Epiglycanin_C PF14654 Domain 6 31 90.30 53 13.41 Changed Mucin, catalytic, TM and cytoplasmic tail region
Epiglycanin_TR PF05647 Repeat 15 222 59.20 46 101.98 Changed Tandem-repeating region of mucin, epiglycanin-like
Epimerase PF01370 Family 96 127456 213.90 19 62.54 Changed NAD dependent epimerase/dehydratase family
Epimerase_2 PF02350 Family 97 25054 337.20 41 90.45 Changed UDP-N-acetylglucosamine 2-epimerase
EPL1 PF10513 Family 122 1641 165.50 21 18.00 Changed Enhancer of polycomb-like
EpmC PF04315 Family 45 4565 162.40 70 86.57 Changed Elongation factor P hydroxylase
EpoR_lig-bind PF09067 Domain 12 665 97.90 30 19.27 Changed Erythropoietin receptor, ligand binding
EPO_TPO PF00758 Domain 13 154 147.30 39 61.84 Changed Erythropoietin/thrombopoietin
EppA_BapA PF07268 Family 2 87 121.30 59 82.44 Changed Exported protein precursor (EppA/BapA)
EpsG PF14897 Family 70 2740 315.80 15 90.21 Changed EpsG family
Epsilon_antitox PF08998 Domain 2 364 85.00 78 98.03 Changed Bacterial epsilon antitoxin
EPSP_synthase PF00275 Family 21 46745 397.20 29 91.73 Changed EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
EPTP PF03736 Repeat 227 2274 44.20 24 18.83 Changed EPTP domain
EpuA PF11772 Family 40 1896 46.00 44 72.19 Changed DNA-directed RNA polymerase subunit beta
EPV_E5 PF08135 Family 1 33 40.00 79 93.23 Changed Major transforming protein E5 family
Equine_IAV_S2 PF06502 Family 2 160 55.90 66 93.07 Changed Equine infectious anaemia virus S2 protein
ER PF01133 Family 56 399 93.40 51 67.74 Changed Enhancer of rudimentary
ER-remodelling PF14755 Domain 5 137 141.80 70 10.31 Changed Intracellular membrane remodeller
ERAP1_C PF11838 Domain 817 8564 303.30 20 36.29 Changed ERAP1-like C-terminal domain
ERbeta_N PF12497 Family 19 251 106.00 42 20.04 Changed Estrogen receptor beta
ERCC3_RAD25_C PF16203 Domain 41 3723 198.60 55 34.06 New ERCC3/RAD25/XPB C-terminal helicase
ERCC4 PF02732 Domain 158 3917 136.00 33 23.19 Changed ERCC4 domain
ERF PF04404 Family 29 2758 149.10 24 66.59 Changed ERF superfamily
eRF1_1 PF03463 Domain 284 2133 123.30 30 31.06 Changed eRF1 domain 1
eRF1_2 PF03464 Domain 22 2096 129.30 30 32.39 Changed eRF1 domain 2
eRF1_3 PF03465 Domain 34 2290 116.60 32 29.78 Changed eRF1 domain 3
Erf4 PF10256 Domain 129 741 114.50 29 45.66 Changed Golgin subfamily A member 7/ERF4 family
Erg28 PF03694 Family 133 477 112.80 35 75.77 Changed Erg28 like protein
ERG2_Sigma1R PF04622 Family 112 511 192.40 38 83.99 Changed ERG2 and Sigma1 receptor like protein
ERG4_ERG24 PF01222 Family 5 1824 366.70 30 87.03 Changed Ergosterol biosynthesis ERG4/ERG24 family
ERGIC_N PF13850 Domain 333 1616 88.50 33 22.60 Changed Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
ERK-JNK_inhib PF15002 Family 19 154 176.30 41 68.68 Changed ERK and JNK pathways, inhibitor
ERM PF00769 Family 72 729 227.80 33 43.21 Changed Ezrin/radixin/moesin family
ErmC PF06308 Family 1 99 27.90 96 99.14 Changed 23S rRNA methylase leader peptide (ErmC)
ERO1 PF04137 Family 175 884 334.50 35 73.90 Changed Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
ERp29 PF07749 Domain 165 550 91.60 30 27.05 Changed Endoplasmic reticulum protein ERp29, C-terminal domain
ERp29_N PF07912 Domain 3 142 118.30 48 45.96 Changed ERp29, N-terminal domain
Erp_C PF06780 Family 4 98 137.30 48 40.44 Changed Erp protein C-terminus
Erv26 PF04148 Family 76 463 188.00 38 87.34 Changed Transmembrane adaptor Erv26
Erythro-docking PF09277 Domain 2 14 54.60 48 2.47 Changed Erythronolide synthase, docking
Erythrovirus_X PF06795 Family 1 26 74.50 95 99.03 Changed Erythrovirus X protein
Erythro_esteras PF05139 Family 181 3218 328.20 44 58.66 Changed Erythromycin esterase
Eryth_link_C PF16915 Domain 13 16 116.40 24 52.60 New Annelid erythrocruorin linker subunit C-terminus
Ery_res_leader1 PF08051 Family 3 18 15.00 72 8.64 Changed Erythromycin resistance leader peptide
Ery_res_leader2 PF08057 Family 1 2 14.00 100 100.00 Changed Erythromycin resistance leader peptide
ER_lumen_recept PF00810 Family 257 1423 137.90 42 58.35 Changed ER lumen protein retaining receptor
Es2 PF09751 Family 65 643 315.20 25 76.27 Changed Nuclear protein Es2
ESAG1 PF03238 Family 11 56 220.90 56 70.67 Changed ESAG protein
ESCRT-II PF05871 Family 154 602 136.60 34 58.25 Changed ESCRT-II complex subunit
ESM4 PF15952 Family 14 99 163.00 30 98.54 New Enhancer of split M4 family
ESP PF16590 Family 35 51 55.80 28 57.83 New Exocrine gland-secreting peptide
EspA PF03433 Family 7 1506 172.70 55 94.52 Changed EspA-like secreted protein
EspB PF05802 Family 3 879 264.50 51 98.76 Changed Enterobacterial EspB protein
EspF PF04806 Repeat 3 1515 42.20 73 71.47 Changed EspF protein repeat
EspG PF06872 Family 4 620 377.80 86 97.35 Changed EspG protein
ESPR PF13018 Domain 157 11406 23.60 47 1.75 Changed Extended Signal Peptide of Type V secretion system
ESR1_C PF12743 Domain 19 132 42.70 55 8.73 Changed Oestrogen-type nuclear receptor final C-terminal
EssA PF10661 Family 4 4320 127.80 86 83.94 Changed WXG100 protein secretion system (Wss), protein EssA
ESSS PF10183 Family 20 442 103.30 24 71.33 Changed ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
EST1 PF10374 Domain 132 861 121.50 24 12.70 Changed Telomerase activating protein Est1
EST1_DNA_bind PF10373 Domain 68 1469 233.50 17 30.06 Changed Est1 DNA/RNA binding domain
Esterase PF00756 Domain 20 51643 238.10 19 74.74 Changed Putative esterase
Esterase_phd PF10503 Family 2 5552 168.90 38 50.95 Changed Esterase PHB depolymerase
ESX-1_EspG PF14011 Family 135 7225 253.70 36 88.88 Changed EspG family
ET PF01684 Family 55 298 79.10 36 78.32 Changed ET module
ETAA1 PF15350 Family 18 101 519.40 34 90.69 Changed Ewing's tumour-associated antigen 1 homologue
ETC_C1_NDUFA4 PF04800 Family 170 1434 94.70 42 65.71 Changed ETC complex I subunit conserved region
ETC_C1_NDUFA5 PF04716 Family 133 549 57.30 37 33.00 Changed ETC complex I subunit conserved region
ETF PF01012 Domain 129 35895 175.70 22 61.35 Changed Electron transfer flavoprotein domain
ETF_alpha PF00766 Domain 535 18500 82.90 48 26.20 Changed Electron transfer flavoprotein FAD-binding domain
ETF_QO PF05187 Family 44 4581 102.20 60 19.11 Changed Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S
EthD PF07110 Domain 56 3502 84.20 34 45.74 Changed EthD domain
Etmic-2 PF06670 Family 2 22 221.20 43 99.77 Changed Microneme protein Etmic-2
ETRAMP PF09716 Family 42 311 86.30 25 50.16 Changed Malarial early transcribed membrane protein (ETRAMP)
Ets PF00178 Domain 164 3260 78.00 51 20.03 Changed Ets-domain
ETS_PEA3_N PF04621 Family 36 351 271.70 46 68.89 Changed PEA3 subfamily ETS-domain transcription factor N terminal domain
ETX_MTX2 PF03318 Family 15 389 199.80 14 65.35 Changed Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2
Euplotes_phero PF05842 Family 6 8 134.00 47 88.96 Changed Euplotes octocarinatus mating pheromone protein
EURL PF06937 Family 4 97 240.50 56 91.75 Changed EURL protein
EutA PF06277 Family 15 3845 447.80 69 99.05 Changed Ethanolamine utilisation protein EutA
EutB PF06751 Family 118 5880 425.80 67 94.83 Changed Ethanolamine ammonia lyase large subunit (EutB)
EutC PF05985 Family 185 5828 230.70 53 80.76 Changed Ethanolamine ammonia-lyase light chain (EutC)
EutH PF04346 Family 62 4289 370.80 72 95.13 Changed Ethanolamine utilisation protein, EutH
EutK_C PF16365 Domain 2 2838 54.90 90 33.42 New Ethanolamine utilization protein EutK C-terminus
EutN_CcmL PF03319 Domain 197 6090 83.00 54 90.01 Changed Ethanolamine utilisation protein EutN/carboxysome
EutQ PF06249 Domain 4 4383 140.70 57 70.70 Changed Ethanolamine utilisation protein EutQ
EVC2_like PF12297 Family 16 92 363.70 47 35.83 Changed Ellis van Creveld protein 2 like protein
EVE PF01878 Domain 138 7465 132.80 46 40.08 Changed EVE domain
EVI2A PF05399 Family 11 57 192.00 56 91.89 Changed Ectropic viral integration site 2A protein (EVI2A)
Evr1_Alr PF04777 Family 354 1631 95.40 29 29.66 Changed Erv1 / Alr family
ExbD PF02472 Family 45 24351 131.00 27 90.89 Changed Biopolymer transport protein ExbD/TolR
Exc PF07825 Domain 2 2241 72.60 42 85.93 Changed Excisionase-like protein
Excalibur PF05901 Domain 162 6056 36.40 62 17.77 Changed Excalibur calcium-binding domain
Exo5 PF09810 Family 75 639 260.10 23 68.73 Changed Exonuclease V - a 5' deoxyribonuclease
Exo70 PF03081 Family 298 1741 324.00 22 57.50 Changed Exo70 exocyst complex subunit
Exo84_C PF16528 Domain 31 623 200.40 25 28.54 New Exocyst component 84 C-terminal
ExoD PF06055 Family 160 780 177.70 27 86.09 Changed Exopolysaccharide synthesis, ExoD
Exonuc_VIII PF06630 Family 2 2206 162.40 46 24.61 Changed Enterobacterial exodeoxyribonuclease VIII
Exonuc_VII_L PF02601 Family 574 22518 252.80 33 69.83 Changed Exonuclease VII, large subunit
Exonuc_VII_S PF02609 Family 891 18296 52.00 40 66.16 Changed Exonuclease VII small subunit
Exonuc_V_gamma PF04257 Family 60 9222 700.90 36 65.20 Changed Exodeoxyribonuclease V, gamma subunit
Exonuc_X-T_C PF08411 Family 140 4615 259.50 64 55.06 Changed Exonuclease C-terminal
EXOSC1 PF10447 Domain 13 614 59.40 40 28.86 Changed Exosome component EXOSC1/CSL4
Exosortase_EpsH PF09721 Family 192 943 235.70 17 68.31 Changed Transmembrane exosortase (Exosortase_EpsH)
Exostosin PF03016 Family 33 3017 260.30 20 52.81 Changed Exostosin family
Exotox-A_bind PF09101 Domain 2 397 200.30 49 30.82 Changed Exotoxin A binding
Exotox-A_cataly PF09009 Domain 1 281 218.90 74 35.76 Changed Exotoxin A catalytic
Exotox-A_target PF09102 Domain 1 276 133.20 73 21.44 Changed Exotoxin A, targeting
Exo_endo_phos PF03372 Domain 322 63758 251.90 15 66.10 Changed Endonuclease/Exonuclease/phosphatase family
Exo_endo_phos_2 PF14529 Domain 82 3082 112.40 19 16.79 Changed Endonuclease-reverse transcriptase
EXS PF03124 Family 348 1623 284.40 27 50.59 Changed EXS family
ExsD PF16806 Domain 4 299 236.70 61 84.02 New Antiactivator protein ExsD
Extensin-like_C PF06904 Family 94 2624 173.80 44 66.81 Changed Extensin-like protein C-terminus
Extensin_1 PF02095 Repeat 13 625 9.40 74 52.53 Changed Extensin-like protein repeat
Extensin_2 PF04554 Family 14 748 49.80 71 72.00 Changed Extensin-like region
EZH2_WD-Binding PF11616 Family 12 199 29.90 67 4.74 Changed WD repeat binding protein EZH2
EzrA PF06160 Family 96 6753 551.70 54 97.97 Changed Septation ring formation regulator, EzrA
E_Pc_C PF06752 Family 18 188 209.50 52 28.86 Changed Enhancer of Polycomb C-terminus
E_raikovi_mat PF06360 Family 6 6 35.30 37 62.72 Changed Euplotes raikovi mating pheromone
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