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Browse Pfam families

New Top twenty Numbers A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
ID Accession Type Number of sequences Average length Average %id Average coverage Has 3D Change status Description
Seed Full
H-kinase_dim PF02895 Domain 66 8814 68.80 41 9.28 Changed Signal transducing histidine kinase, homodimeric domain
H-K_ATPase_N PF09040 Domain 2 43 40.70 81 4.25 Changed Gastric H+/K+-ATPase, N terminal domain
H2TH PF06831 Domain 14 26704 90.30 34 33.43 Changed Formamidopyrimidine-DNA glycosylase H2TH domain
HA PF03457 Domain 435 2062 65.00 26 31.85 Changed Helicase associated domain
HA2 PF04408 Domain 453 19135 100.20 29 9.65 Changed Helicase associated domain (HA2)
HABP4_PAI-RBP1 PF04774 Family 86 811 101.40 26 29.13 Changed Hyaluronan / mRNA binding family
HAD PF12710 Family 270 25601 248.40 18 44.60 Changed haloacid dehalogenase-like hydrolase
HAD_2 PF13419 Family 162 112320 182.00 18 77.25 Changed Haloacid dehalogenase-like hydrolase
Haemadin PF09065 Domain 2 2 27.00 100 46.55 Changed Haemadin
Haemagg_act PF05860 Domain 44 6968 126.30 29 7.22 Changed haemagglutination activity domain
Haemocyan_bet_s PF14830 Family 27 238 101.80 39 24.81 Changed Haemocyanin beta-sandwich
Haemolytic PF01809 Family 831 15169 65.80 52 71.03 Changed Haemolytic domain
Haem_bd PF14376 Family 113 3372 134.20 63 31.46 Changed Haem-binding domain
Haem_degrading PF03928 Family 603 9439 126.60 30 70.72 Changed Haem-degrading
Haem_oxygenas_2 PF14518 Family 240 5172 175.80 19 52.68 Changed Iron-containing redox enzyme
HAGH_C PF16123 Family 540 7849 83.10 44 32.47 New Hydroxyacylglutathione hydrolase C-terminus
Hairpins PF04877 Family 11 334 228.90 27 94.18 Changed HrpZ
Hairy_orange PF07527 Domain 125 1343 40.10 33 14.05 Changed Hairy Orange
Halogen_Hydrol PF10112 Family 36 6119 194.20 54 88.85 Changed 5-bromo-4-chloroindolyl phosphate hydrolysis protein
Halo_GVPC PF05465 Repeat 27 78 31.50 34 39.22 Changed Halobacterial gas vesicle protein C (GVPC) repeat
HalX PF08663 Domain 45 347 66.80 31 30.78 Changed HalX domain
HALZ PF02183 Family 129 1145 39.30 42 13.80 Changed Homeobox associated leucine zipper
Ham1p_like PF01725 Domain 1316 20250 186.90 45 84.96 Changed Ham1 family
Hamartin PF04388 Family 29 383 484.50 22 58.68 Changed Hamartin protein
HAMP PF00672 Family 213 218359 70.90 20 12.87 Changed HAMP domain
HAND PF09110 Domain 111 717 100.90 41 9.96 Changed HAND
Hanta_G1 PF01567 Family 1 650 335.80 57 50.23 Changed Hantavirus glycoprotein G1
Hanta_G2 PF01561 Family 6 1582 202.10 44 54.94 Changed Hantavirus glycoprotein G2
Hanta_nucleocap PF00846 Family 1 1977 242.40 54 99.86 Changed Hantavirus nucleocapsid protein
HAP PF03866 Family 2 7 139.70 43 49.87 Changed Hydrophobic abundant protein (HAP)
HAP1_N PF04849 Family 30 451 224.10 38 33.68 Changed HAP1 N-terminal conserved region
HAP2-GCS1 PF10699 Domain 45 192 47.70 39 6.46 Changed Male gamete fusion factor
Hap4_Hap_bind PF10297 Motif 15 306 16.80 78 3.12 Changed Minimal binding motif of Hap4 for binding to Hap2/3/5
HapK PF11639 Family 2 43 102.10 36 81.48 Changed REDY-like protein HapK
Harakiri PF15196 Family 2 15 88.40 89 100.00 Changed Activator of apoptosis harakiri
HARE-HTH PF05066 Family 44 7572 68.50 54 28.87 Changed HB1, ASXL, restriction endonuclease HTH domain
HARP PF07443 Family 70 241 53.80 40 10.91 Changed HepA-related protein (HARP)
HAS-barrel PF09378 Domain 60 561 91.40 20 19.46 Changed HAS barrel domain
HasA PF06438 Domain 6 427 204.60 49 99.36 Changed Heme-binding protein A (HasA)
HAT PF02184 Family 3 789 32.10 46 6.78 Changed HAT (Half-A-TPR) repeat
Hat1_N PF10394 Domain 185 592 157.60 27 34.06 Changed Histone acetyl transferase HAT1 N-terminus
HATPase_c PF02518 Domain 659 485514 114.10 24 19.50 Changed Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HATPase_c_2 PF13581 Domain 78 17637 123.90 26 40.53 Changed Histidine kinase-like ATPase domain
HATPase_c_3 PF13589 Domain 24 19636 125.70 33 19.21 Changed Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HATPase_c_4 PF13749 Domain 89 4643 86.00 28 18.74 Changed Putative ATP-dependent DNA helicase recG C-terminal
HATPase_c_5 PF14501 Domain 42 12700 102.80 32 25.48 Changed GHKL domain
HAT_KAT11 PF08214 Domain 25 901 297.50 28 22.79 Changed Histone acetylation protein
HAUS-augmin3 PF14932 Family 46 213 229.70 27 43.41 Changed HAUS augmin-like complex subunit 3
HAUS2 PF15003 Family 5 166 194.90 33 85.40 Changed HAUS augmin-like complex subunit 2
HAUS4 PF14735 Family 23 192 204.90 31 60.82 Changed HAUS augmin-like complex subunit 4
HAUS5 PF14817 Family 26 171 486.50 28 88.78 Changed HAUS augmin-like complex subunit 5
HAUS6_N PF14661 Family 59 396 214.30 21 33.21 Changed HAUS augmin-like complex subunit 6 N-terminus
HAV_VP PF12944 Domain 2 888 125.50 98 28.86 Changed Hepatitis A virus viral protein VP
HBB PF06777 Domain 40 906 140.90 30 18.89 Changed Helical and beta-bridge domain
HBM PF16591 Family 15 1317 240.20 22 39.44 New Helical bimodular sensor domain
HbrB PF08539 Domain 80 454 138.50 29 23.27 Changed HbrB-like
HBS1_N PF08938 Domain 104 460 86.40 24 12.99 Changed HBS1 N-terminus
Hc1 PF07432 Family 4 514 75.20 49 96.78 Changed Histone H1-like protein Hc1
HC2 PF07382 Family 8 638 155.10 47 68.79 Changed Histone H1-like nucleoprotein HC2
HCaRG PF07258 Family 268 1650 158.90 16 81.89 Changed HCaRG protein
HCBP_related PF06594 Domain 165 2053 42.00 28 9.38 Changed Haemolysin-type calcium binding protein related domain
Hce2 PF14856 Family 114 284 100.60 27 21.25 Changed Pathogen effector; putative necrosis-inducing factor
HCMVantigenic_N PF12154 Family 3 123 36.30 76 9.99 Changed Glycoprotein B N-terminal antigenic domain of HCMV
HCMV_UL139 PF12507 Family 8 91 103.80 45 63.13 Changed Human Cytomegalovirus UL139 protein
HCNGP PF07818 Family 105 521 94.60 32 31.95 Changed HCNGP-like protein
HCO3_cotransp PF00955 Family 92 3605 285.30 25 53.95 Changed HCO3- transporter family
HCR PF07111 Coiled-coil 3 173 383.40 48 90.65 Changed Alpha helical coiled-coil rod protein (HCR)
HCV_capsid PF01543 Family 5 15034 105.10 88 14.73 Changed Hepatitis C virus capsid protein
HCV_core PF01542 Family 1 12975 61.90 90 7.40 Changed Hepatitis C virus core protein
HCV_env PF01539 Family 4 53918 82.80 67 26.36 Changed Hepatitis C virus envelope glycoprotein E1
HCV_NS1 PF01560 Family 10 54183 118.30 61 38.10 Changed Hepatitis C virus non-structural protein E2/NS1
HCV_NS2 PF01538 Family 29 5498 185.70 74 10.51 Changed Hepatitis C virus non-structural protein NS2
HCV_NS4a PF01006 Family 15 7276 54.00 87 4.58 Changed Hepatitis C virus non-structural protein NS4a
HCV_NS4b PF01001 Family 11 2589 182.50 80 8.37 Changed Hepatitis C virus non-structural protein NS4b
HCV_NS5a PF01506 Family 19 8321 22.60 84 2.19 Changed Hepatitis C virus non-structural 5a protein membrane anchor
HCV_NS5a_1a PF08300 Domain 1 8527 61.70 82 6.01 Changed Hepatitis C virus non-structural 5a zinc finger domain
HCV_NS5a_1b PF08301 Domain 20 13381 75.10 83 10.14 Changed Hepatitis C virus non-structural 5a domain 1b
HCV_NS5a_C PF12941 Family 1 19485 192.60 80 35.53 Changed HCV NS5a protein C-terminal region
HD PF01966 Family 154 94574 119.30 19 28.59 Changed HD domain
HD-ZIP_N PF04618 Domain 24 146 99.60 41 35.05 Changed HD-ZIP protein N terminus
HDA2-3 PF11496 Domain 26 230 280.70 23 31.99 Changed Class II histone deacetylase complex subunits 2 and 3
HDAC4_Gln PF12203 Domain 11 282 87.80 69 9.77 Changed Glutamine rich N terminal domain of histone deacetylase 4
HDC PF02329 Domain 5 186 257.10 53 93.80 Changed Histidine carboxylase PI chain
HdeA PF06411 Domain 30 5503 89.80 42 81.97 Changed HdeA/HdeB family
hDGE_amylase PF14701 Domain 64 594 359.70 36 27.94 Changed glucanotransferase domain of human glycogen debranching enzyme
HDNR PF15115 Family 16 103 154.90 32 81.97 Changed Domain of unknown function with conserved HDNR motif
HDOD PF08668 Domain 53 8086 177.80 20 47.18 Changed HDOD domain
HDPD PF02924 Domain 73 3972 108.20 46 94.34 Changed Bacteriophage lambda head decoration protein D
HDV_ag PF01517 Family 1 1235 116.10 80 89.38 Changed Hepatitis delta virus delta antigen
HD_2 PF12917 Family 2 4904 211.30 86 98.35 Changed HD containing hydrolase-like enzyme
HD_3 PF13023 Domain 87 7373 165.30 35 75.48 Changed HD domain
HD_4 PF13328 Family 67 27914 150.20 42 22.39 Changed HD domain
HD_5 PF13487 Domain 45 7067 64.00 32 14.10 Changed HD domain
HD_assoc PF13286 Domain 338 8041 89.10 24 21.07 Changed Phosphohydrolase-associated domain
Head-tail_con PF12236 Family 41 947 440.40 29 86.31 Changed Bacteriophage head to tail connecting protein
Headcase PF16002 Family 14 187 167.30 48 41.60 New Headcase protein
Head_binding PF09008 Domain 5 701 109.00 77 16.17 Changed Head binding
HEAT PF02985 Repeat 464 2799 30.60 27 3.28 Changed HEAT repeat
HEAT_2 PF13646 Family 199 35329 84.50 21 24.82 Changed HEAT repeats
HEAT_EZ PF13513 Repeat 155 2041 55.50 33 6.05 Changed HEAT-like repeat
HEAT_PBS PF03130 Repeat 221 714 27.40 31 9.00 Changed PBS lyase HEAT-like repeat
HECA PF15353 Family 19 158 97.80 53 20.66 Changed Headcase protein family homologue
HECT PF00632 Domain 91 7961 293.70 28 20.00 Changed HECT-domain (ubiquitin-transferase)
HECT_2 PF09814 Family 104 567 326.50 17 76.34 Changed HECT-like Ubiquitin-conjugating enzyme (E2)-binding
HECW_N PF16562 Domain 14 176 111.30 64 8.78 New N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
hEGF PF12661 Domain 447 7425 12.90 50 2.14 Changed Human growth factor-like EGF
HeH PF12949 Domain 40 1152 34.30 46 12.86 Changed HeH/LEM domain
Helicase_C PF00271 Family 423 299814 116.60 20 14.07 Changed Helicase conserved C-terminal domain
Helicase_C_2 PF13307 Domain 106 23613 163.50 31 21.61 Changed Helicase C-terminal domain
Helicase_C_3 PF13625 Domain 216 5760 124.90 41 19.02 Changed Helicase conserved C-terminal domain
Helicase_C_4 PF13871 Domain 75 804 249.90 41 20.43 Changed C-terminal domain on Strawberry notch homologue
Helicase_IV_N PF12462 Family 36 3522 163.80 71 24.08 Changed DNA helicase IV / RNA helicase N terminal
Helicase_RecD PF05127 Domain 106 4923 147.40 58 21.63 Changed Helicase
Helicase_Sgs1 PF11408 Family 5 45 78.30 42 5.93 Changed Sgs1 RecQ helicase
Helitron_like_N PF14214 Family 145 1722 151.80 23 17.25 Changed Helitron helicase-like domain at N-terminus
HeLo PF14479 Domain 101 714 191.20 16 30.95 Changed Prion-inhibition and propagation
Helo_like_N PF17111 Family 33 689 175.10 17 28.52 New Fungal N-terminal domain of STAND proteins
HELP PF03451 Family 59 1174 67.80 38 8.36 Changed HELP motif
HEM4 PF02602 Family 79 19513 220.70 26 71.20 Changed Uroporphyrinogen-III synthase HemD
Hemagglutinin PF00509 Family 3 80356 442.20 50 96.20 Changed Haemagglutinin
Hema_esterase PF03996 Domain 3 464 321.20 44 75.93 Changed Hemagglutinin esterase
Hema_HEFG PF02710 Family 3 436 131.30 45 29.69 Changed Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein
Hema_stalk PF08720 Domain 1 157 173.10 96 27.20 Changed Influenza C hemagglutinin stalk
HemeBinding_Shp PF11545 Family 1 277 150.40 75 41.30 Changed Cell surface heme-binding protein Shp
Hemerythrin PF01814 Domain 188 24547 130.40 20 60.77 Changed Hemerythrin HHE cation binding domain
Heme_oxygenase PF01126 Domain 18 3263 185.80 23 81.68 Changed Heme oxygenase
HemN_C PF06969 Domain 49 21603 65.80 27 16.32 Changed HemN C-terminal domain
Hemocyanin_C PF03723 Domain 110 865 234.10 30 36.17 Changed Hemocyanin, ig-like domain
Hemocyanin_M PF00372 Domain 92 1045 230.40 30 41.88 Changed Hemocyanin, copper containing domain
Hemocyanin_N PF03722 Domain 93 848 111.20 28 17.40 Changed Hemocyanin, all-alpha domain
HemolysinCabind PF00353 Repeat 305 80987 17.70 44 17.02 Changed Hemolysin-type calcium-binding repeat (2 copies)
Hemolysin_N PF12563 Family 3 228 174.60 68 26.96 Changed Hemolytic toxin N terminal
Hemopexin PF00045 Repeat 76 7108 44.80 27 26.69 Changed Hemopexin
hemP PF10636 Family 101 4434 36.90 64 58.25 Changed Hemin uptake protein hemP
HemS PF05171 Domain 65 4773 130.00 38 73.36 Changed Haemin-degrading HemS.ChuX domain
HemX PF04375 Family 29 5002 351.90 49 87.37 Changed HemX
HemY_N PF07219 Family 207 5664 107.30 49 25.92 Changed HemY protein N-terminus
Hen1_L PF12623 Domain 61 267 235.10 51 50.59 Changed RNA repair, ligase-Pnkp-associating, region of Hen1
Hepar_II_III PF07940 Family 76 4154 226.30 17 36.15 Changed Heparinase II/III-like protein
Hepar_II_III_N PF16889 Domain 28 1781 278.20 25 45.57 New Heparinase II/III N-terminus
Hepatitis_core PF00906 Domain 2 29492 63.50 37 91.76 Changed Hepatitis core antigen
Hepcidin PF06446 Domain 19 223 52.40 40 61.11 Changed Hepcidin
HEPN PF05168 Family 85 2461 114.40 17 31.15 Changed HEPN domain
HEPPP_synt_1 PF07307 Family 16 4577 146.80 81 74.49 Changed Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
Hepsin-SRCR PF09272 Domain 2 74 101.80 64 23.69 Changed Hepsin, SRCR
Hep_59 PF07052 Family 98 473 99.00 32 32.72 Changed Hepatocellular carcinoma-associated antigen 59
Hep_core_N PF08290 Domain 1 10196 27.00 97 24.85 Changed Hepatitis core protein, putative zinc finger
Herp-Cyclin PF09241 Domain 1 3 106.00 81 41.30 Changed Herpesviridae viral cyclin
Herpes_alk_exo PF01771 Family 9 292 362.80 22 73.28 Changed Herpesvirus alkaline exonuclease
Herpes_BBRF1 PF04793 Family 4 29 272.10 29 92.67 Changed BRRF1-like protein
Herpes_BLLF1 PF05109 Family 1 293 419.90 56 98.71 Changed Herpes virus major outer envelope glycoprotein (BLLF1)
Herpes_BLRF2 PF05812 Family 5 39 117.90 35 78.63 Changed Herpesvirus BLRF2 protein
Herpes_BMRF2 PF04633 Family 5 27 348.00 32 98.05 Changed Herpesvirus BMRF2 protein
Herpes_BTRF1 PF04682 Family 5 33 244.00 38 65.64 Changed Herpesvirus BTRF1 protein conserved region
Herpes_capsid PF06112 Family 4 23 156.00 33 91.46 Changed Gammaherpesvirus capsid protein
Herpes_DNAp_acc PF04929 Family 5 28 389.60 36 98.35 Changed Herpes DNA replication accessory factor
Herpes_env PF01673 Family 5 244 352.50 26 87.87 Changed Herpesvirus putative major envelope glycoprotein
Herpes_gE PF02480 Family 5 382 323.20 35 79.76 Changed Alphaherpesvirus glycoprotein E
Herpes_gI PF01688 Domain 5 191 155.60 43 43.07 Changed Alphaherpesvirus glycoprotein I
Herpes_glycop PF01528 Family 7 214 311.90 29 88.97 Changed Herpesvirus glycoprotein M
Herpes_glycop_D PF01537 Domain 22 348 111.20 34 25.17 Changed Herpesvirus glycoprotein D/GG/GX domain
Herpes_glycop_H PF02489 Family 9 361 485.80 23 73.97 Changed Herpesvirus glycoprotein H
Herpes_gp2 PF05955 Family 5 21 226.70 66 32.20 Changed Equine herpesvirus glycoprotein gp2
Herpes_Helicase PF02689 Family 9 1895 195.80 28 36.45 Changed Helicase
Herpes_heli_pri PF05774 Family 3 25 125.20 28 36.60 Changed Herpesvirus helicase-primase complex component
Herpes_HEPA PF03324 Family 9 201 92.00 31 12.50 Changed Herpesvirus DNA helicase/primase complex associated protein
Herpes_ICP4_C PF03585 Family 3 197 346.60 57 30.38 Changed Herpesvirus ICP4-like protein C-terminal region
Herpes_ICP4_N PF03584 Family 4 179 172.10 52 12.34 Changed Herpesvirus ICP4-like protein N-terminal region
Herpes_IE1 PF07340 Family 1 167 224.10 66 59.56 Changed Cytomegalovirus IE1 protein
Herpes_IE2_3 PF03361 Family 5 117 158.30 38 27.84 Changed Herpes virus intermediate/early protein 2/3
Herpes_IE68 PF02479 Family 4 96 122.50 39 37.00 Changed Herpesvirus immediate early protein
Herpes_IR6 PF06307 Family 4 45 130.80 62 84.14 Changed Herpesvirus IR6 protein
Herpes_LAMP2 PF06126 Family 2 26 472.50 68 99.79 Changed Herpesvirus Latent membrane protein 2
Herpes_LMP1 PF05297 Family 2 1161 131.20 71 102.87 Changed Herpesvirus latent membrane protein 1 (LMP1)
Herpes_LMP2 PF07415 Family 1 326 221.30 55 99.81 Changed Gammaherpesvirus latent membrane protein (LMP2) protein
Herpes_LP PF03363 Family 2 66 115.90 73 139.34 Changed Herpesvirus leader protein
Herpes_MCP PF03122 Family 11 236 1170.50 37 98.59 Changed Herpes virus major capsid protein
Herpes_ORF11 PF04797 Family 9 111 278.80 23 71.27 Changed Herpesvirus dUTPase protein
Herpes_ori_bp PF02399 Family 5 319 380.40 21 53.19 Changed Origin of replication binding protein
Herpes_PAP PF03325 Family 1 70 205.00 43 69.72 Changed Herpesvirus polymerase accessory protein
Herpes_pp38 PF04846 Family 2 36 61.70 58 26.03 Changed Herpesvirus pp38 phosphoprotein
Herpes_pp85 PF04637 Family 2 102 411.70 29 64.04 Changed Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25)
Herpes_TAF50 PF03326 Family 4 58 300.10 18 72.30 Changed Herpesvirus transcription activation factor (transactivator)
Herpes_teg_N PF04843 Family 11 296 174.10 29 6.82 Changed Herpesvirus tegument protein, N-terminal conserved region
Herpes_TK PF00693 Domain 5 591 245.70 52 71.35 Changed Thymidine kinase from herpesvirus
Herpes_TK_C PF08465 Family 5 43 32.80 47 6.21 Changed Thymidine kinase from Herpesvirus C-terminal
Herpes_U15 PF05613 Family 2 8 107.80 67 77.80 Changed Human herpesvirus U15 protein
Herpes_U26 PF07402 Family 2 7 293.00 65 99.18 Changed Human herpesvirus U26 protein
Herpes_U30 PF04523 Family 7 95 843.10 28 91.35 Changed Herpes virus tegument protein U30
Herpes_U34 PF04541 Family 5 165 190.20 29 65.71 Changed Herpesvirus virion protein U34
Herpes_U44 PF04533 Family 3 75 191.00 32 69.82 Changed Herpes virus U44 protein
Herpes_U47 PF05467 Family 1 55 126.00 80 96.77 Changed Herpesvirus glycoprotein U47
Herpes_U5 PF05999 Family 2 83 392.70 45 62.65 Changed Herpesvirus U5-like family
Herpes_U55 PF06501 Family 3 9 426.40 46 96.21 Changed Human herpesvirus U55 protein
Herpes_U59 PF04529 Family 8 48 388.70 39 96.25 Changed Herpesvirus U59 protein
Herpes_UL1 PF05259 Family 4 89 100.80 38 50.42 Changed Herpesvirus glycoprotein L
Herpes_UL14 PF03580 Family 4 88 142.90 53 72.78 Changed Herpesvirus UL14-like protein
Herpes_UL16 PF03044 Family 12 301 228.70 36 93.47 Changed Herpesvirus UL16/UL94 family
Herpes_UL17 PF04559 Family 36 219 513.80 22 94.85 Changed Herpesvirus UL17 protein
Herpes_UL20 PF04544 Family 4 63 170.30 32 76.02 Changed Herpesvirus egress protein UL20
Herpes_UL21 PF03252 Family 3 128 370.90 39 95.09 Changed Herpesvirus UL21
Herpes_UL24 PF01646 Family 10 231 158.40 30 65.87 Changed Herpes virus proteins UL24 and UL76
Herpes_UL25 PF01499 Family 10 204 511.80 28 94.02 Changed Herpesvirus UL25 family
Herpes_UL3 PF03369 Family 3 283 66.20 86 70.01 Changed Herpesvirus UL3 protein
Herpes_UL31 PF02718 Family 8 153 250.80 32 81.80 Changed Herpesvirus UL31-like protein
Herpes_UL32 PF06070 Family 2 80 639.50 43 81.08 Changed Herpesvirus large structural phosphoprotein UL32
Herpes_UL33 PF03581 Family 10 119 75.60 40 57.86 Changed Herpesvirus UL33-like protein
Herpes_UL35 PF04496 Family 3 48 99.10 37 74.44 Changed Herpesvirus UL35 family
Herpes_UL36 PF03586 Family 4 214 217.50 52 10.06 Changed Herpesvirus UL36 tegument protein
Herpes_UL37_1 PF03970 Family 3 100 264.30 41 24.98 Changed Herpesvirus UL37 tegument protein
Herpes_UL37_2 PF07413 Family 2 113 277.60 63 76.49 Changed Betaherpesvirus immediate-early glycoprotein UL37
Herpes_UL4 PF03277 Family 5 88 183.90 43 87.81 Changed Herpesvirus UL4 family
Herpes_UL42 PF02282 Domain 4 240 138.40 35 57.53 Changed DNA polymerase processivity factor (UL42)
Herpes_UL43 PF05072 Family 4 73 364.10 35 90.01 Changed Herpesvirus UL43 protein
Herpes_UL45 PF05473 Family 11 118 156.60 20 44.55 Changed UL45 protein
Herpes_UL46 PF03387 Family 3 90 418.30 44 62.09 Changed Herpesvirus UL46 protein
Herpes_UL47 PF03362 Family 3 140 401.40 34 58.07 Changed Herpesvirus UL47 protein
Herpes_UL49_1 PF03117 Family 6 105 246.20 44 49.89 Changed UL49 family
Herpes_UL49_2 PF04823 Family 4 108 95.50 57 33.53 Changed Herpesvirus UL49 tegument protein
Herpes_UL49_5 PF05702 Family 8 41 93.60 34 98.11 Changed Herpesvirus UL49.5 envelope/tegument protein
Herpes_UL51 PF04540 Family 3 69 156.10 53 64.20 Changed Herpesvirus UL51 protein
Herpes_UL52 PF03121 Family 38 505 68.90 24 9.10 Changed Herpesviridae UL52/UL70 DNA primase
Herpes_UL55 PF04537 Family 3 51 164.70 40 90.33 Changed Herpesvirus UL55 protein
Herpes_UL56 PF04534 Family 2 34 184.30 64 80.85 Changed Herpesvirus UL56 protein
Herpes_UL6 PF01763 Family 11 248 442.10 31 82.88 Changed Herpesvirus UL6 like
Herpes_UL69 PF05459 Family 12 202 208.30 30 37.78 Changed Herpesvirus transcriptional regulator family
Herpes_UL7 PF01677 Family 11 155 219.30 26 76.27 Changed Herpesvirus UL7 like
Herpes_UL73 PF03554 Family 9 267 100.80 47 86.90 Changed UL73 viral envelope glycoprotein
Herpes_UL74 PF07982 Family 1 197 202.90 60 80.26 Changed Herpes UL74 glycoproteins
Herpes_UL79 PF03049 Family 6 82 246.10 38 90.36 Changed UL79 family
Herpes_UL82_83 PF05784 Family 3 138 336.80 32 62.73 Changed Betaherpesvirus UL82/83 protein N terminus
Herpes_UL87 PF03043 Family 5 112 507.40 43 70.28 Changed Herpesvirus UL87 family
Herpes_UL92 PF03048 Family 7 107 162.20 27 66.76 Changed UL92 family
Herpes_UL95 PF03038 Family 6 103 365.70 41 86.87 Changed UL95 family
Herpes_US12 PF05363 Family 2 21 81.00 52 94.92 Changed Herpesvirus US12 family
Herpes_US9 PF06072 Family 2 57 57.30 47 47.53 Changed Alphaherpesvirus tegument protein US9
Herpes_V23 PF01802 Family 11 538 167.20 63 98.16 Changed Herpesvirus VP23 like capsid protein
Herpes_VP19C PF03327 Family 11 155 289.20 26 75.00 Changed Herpesvirus capsid shell protein VP19C
Herpeto_peptide PF14409 Family 3 6 56.50 50 98.55 Changed Ribosomally synthesized peptide in Herpetosiphon
HERV-K_env_2 PF13804 Domain 11 375 164.60 87 42.95 Changed Retro-transcribing viruses envelope glycoprotein
HERV-K_REC PF15695 Family 2 67 82.10 77 25.03 New Rec (regulator of expression encoded by corf) of HERV-K-113
HET PF06985 Family 99 8364 139.30 21 22.02 Changed Heterokaryon incompatibility protein (HET)
Het-C PF07217 Family 42 753 430.10 40 68.97 Changed Heterokaryon incompatibility protein Het-C
HET-S PF17108 Family 13 29 21.00 62 1.98 New N-terminal small S protein of HET, non-prionic
HET-s_218-289 PF11558 Motif 16 52 63.70 38 22.95 Changed Het-s 218-289
HEV_ORF1 PF02444 Family 1 389 84.30 77 96.96 Changed Hepatitis E virus ORF-2 (Putative capsid protein)
Hexapep PF00132 Repeat 216 254578 36.20 24 24.60 Changed Bacterial transferase hexapeptide (six repeats)
Hexapep_2 PF14602 Repeat 57 51322 32.40 34 14.00 Changed Hexapeptide repeat of succinyl-transferase
HEXIM PF15313 Family 33 201 128.40 41 42.75 Changed Hexamethylene bis-acetamide-inducible protein
Hexokinase_1 PF00349 Domain 451 3351 190.90 34 41.19 Changed Hexokinase
Hexokinase_2 PF03727 Domain 470 3653 215.10 31 50.30 Changed Hexokinase
Hexose_dehydrat PF03559 Family 83 452 200.10 37 86.58 Changed NDP-hexose 2,3-dehydratase
Hex_IIIa PF02455 Family 3 214 473.40 67 86.08 Changed Hexon-associated protein (IIIa)
He_PIG PF05345 Family 108 4913 50.70 32 9.68 Changed Putative Ig domain
He_PIG_assoc PF10632 Domain 25 248 27.00 67 5.18 Changed He_PIG associated, NEW1 domain of bacterial glycohydrolase
HflK_N PF12221 Family 107 5103 56.50 64 13.80 Changed Bacterial membrane protein N terminal
HGAL PF15666 Family 24 64 85.40 52 55.12 New Germinal center-associated lymphoma
HGD-D PF06050 Family 376 6759 319.30 27 49.19 Changed 2-hydroxyglutaryl-CoA dehydratase, D-component
hGDE_central PF14702 Domain 138 503 238.10 36 16.70 Changed central domain of human glycogen debranching enzyme
hGDE_N PF14699 Family 143 413 93.50 31 6.36 Changed N-terminal domain from the human glycogen debranching enzyme
HgmA PF04209 Family 12 2961 366.70 36 90.97 Changed homogentisate 1,2-dioxygenase
HGTP_anticodon PF03129 Domain 99 71621 92.00 24 17.13 Changed Anticodon binding domain
HGTP_anticodon2 PF12745 Domain 30 427 221.00 25 14.91 Changed Anticodon binding domain of tRNAs
HGWP PF03578 Repeat 76 1492 27.50 64 31.76 Changed HGWP repeat
HHA PF05321 Family 9 8650 56.90 59 82.35 Changed Haemolysin expression modulating protein
HHH PF00633 Motif 92 34608 29.80 47 10.77 Changed Helix-hairpin-helix motif
HhH-GPD PF00730 Domain 52 56495 139.90 23 49.50 Changed HhH-GPD superfamily base excision DNA repair protein
HHH_2 PF12826 Motif 46 23114 62.20 35 9.88 Changed Helix-hairpin-helix motif
HHH_3 PF12836 Domain 224 34718 64.40 40 14.75 Changed Helix-hairpin-helix motif
HHH_4 PF14490 Family 447 8472 92.50 53 11.64 Changed Helix-hairpin-helix containing domain
HHH_5 PF14520 Domain 257 39835 57.60 29 14.93 Changed Helix-hairpin-helix domain
HHH_6 PF14579 Domain 236 31281 90.20 33 7.64 Changed Helix-hairpin-helix motif
HHH_7 PF14635 Domain 3 595 104.60 40 6.87 Changed Helix-hairpin-helix motif
HHH_8 PF14716 Domain 264 8280 67.60 47 13.47 Changed Helix-hairpin-helix domain
HHV-1_VABD PF16852 Domain 2 29 40.30 90 7.82 New Herpes viral adaptor-to-host cellular mRNA binding domain
HHV-5_US34A PF17087 Family 1 18 63.90 91 100.00 New Herpesvirus US34A protein family
HHV6-IE PF03753 Family 1 52 494.10 56 88.99 Changed Human herpesvirus 6 immediate early protein
HH_signal PF01085 Domain 17 488 128.00 71 35.37 Changed Hedgehog amino-terminal signalling domain
HI0933_like PF03486 Family 47 18129 374.90 38 94.08 Changed HI0933-like protein
HiaBD2 PF15403 Motif 19 50 53.10 48 7.60 Changed HiaBD2_N domain of Trimeric autotransporter adhesin (GIN)
HicA_toxin PF07927 Family 441 5922 56.20 28 72.79 Changed HicA toxin of bacterial toxin-antitoxin,
HicB PF05534 Domain 20 3494 48.60 36 43.58 Changed HicB family
HicB-like_2 PF15970 Domain 2 272 80.20 48 56.11 New HicB_like antitoxin of bacterial toxin-antitoxin system
HicB_lk_antitox PF15919 Domain 31 6480 96.00 28 78.37 New HicB_like antitoxin of bacterial toxin-antitoxin system
Hid1 PF12722 Family 27 405 644.20 28 89.81 Changed High-temperature-induced dauer-formation protein
HIF-1 PF11413 Family 16 439 31.50 63 4.43 Changed Hypoxia-inducible factor-1
HIF-1a_CTAD PF08778 Domain 11 319 36.00 70 4.56 Changed HIF-1 alpha C terminal transactivation domain
HigB-like_toxin PF05015 Family 6 2888 88.00 35 93.75 Changed RelE-like toxin of type II toxin-antitoxin system HigB
HigB_toxin PF09907 Family 164 3449 74.30 44 73.70 Changed HigB_toxin, RelE-like toxic component of a toxin-antitoxin system
HIGH_NTase1 PF05636 Family 202 7850 368.20 52 97.57 Changed HIGH Nucleotidyl Transferase
HIGH_NTase1_ass PF16581 Domain 8 45 189.90 38 50.21 New Cytidyltransferase-related C-terminal region
HIG_1_N PF04588 Family 225 1985 51.80 28 40.47 Changed Hypoxia induced protein conserved region
HILPDA PF15220 Family 4 16 63.80 70 86.82 Changed Hypoxia-inducible lipid droplet-associated
HIM1 PF08732 Family 4 81 258.00 30 82.49 Changed HIM1
HIN PF02760 Family 50 176 163.60 53 43.55 Changed HIN-200/IF120x domain
Hint PF01079 Family 29 744 189.60 28 41.58 Changed Hint module
Hint_2 PF13403 Domain 46 1650 137.00 33 27.10 Changed Hint domain
HIP1_clath_bdg PF16515 Domain 34 192 97.50 48 9.77 New Clathrin-binding domain of Huntingtin-interacting protein 1
HipA_C PF07804 Domain 457 7562 145.60 24 36.73 Changed HipA-like C-terminal domain
HipA_N PF07805 Domain 400 6802 83.70 31 20.19 Changed HipA-like N-terminal domain
HIPIP PF01355 Domain 37 416 63.90 39 59.18 Changed High potential iron-sulfur protein
Hira PF07569 Family 112 609 197.10 26 21.54 Changed TUP1-like enhancer of split
HIRAN PF08797 Domain 51 3550 92.20 39 20.69 Changed HIRAN domain
HIRA_B PF09453 Motif 42 415 22.40 49 2.35 Changed HIRA B motif
Hirudin PF00713 Domain 8 20 57.20 81 94.47 Changed Hirudin
HisG PF01634 Family 766 16453 157.00 43 62.59 Changed ATP phosphoribosyltransferase
HisG_C PF08029 Domain 413 7558 73.40 51 25.03 Changed HisG, C-terminal domain
HisKA PF00512 Domain 265 285270 67.20 25 11.09 Changed His Kinase A (phospho-acceptor) domain
HisKA_2 PF07568 Domain 68 6672 74.80 40 15.00 Changed Histidine kinase
HisKA_3 PF07730 Domain 172 51250 67.10 29 15.17 Changed Histidine kinase
HisKA_4TM PF16926 Family 3 134 157.90 21 41.69 New Archaeal 4TM region of histidine kinase
HisKA_7TM PF16927 Family 169 1991 216.60 16 39.53 New N-terminal 7TM region of histidine kinase
HisK_N PF09385 Domain 9 294 128.00 63 38.10 Changed Histidine kinase N terminal
Histidinol_dh PF00815 Family 695 17315 398.50 45 93.12 Changed Histidinol dehydrogenase
Histone PF00125 Domain 30 25449 106.10 54 80.19 Changed Core histone H2A/H2B/H3/H4
Histone_H2A_C PF16211 Family 164 3823 34.00 60 23.05 New C-terminus of histone H2A
Histone_HNS PF00816 Family 230 12682 93.90 36 73.61 Changed H-NS histone family
Hist_deacetyl PF00850 Domain 85 15804 296.90 32 71.53 Changed Histone deacetylase domain
Hist_rich_Ca-bd PF10529 Repeat 38 206 15.30 60 12.55 Changed Histidine-rich Calcium-binding repeat region
His_binding PF02098 Domain 13 1235 137.60 14 71.10 Changed Tick histamine binding protein
His_biosynth PF00977 Family 135 34008 229.60 35 91.41 Changed Histidine biosynthesis protein
His_kinase PF06580 Family 1960 29448 81.40 37 15.42 Changed Histidine kinase
His_leader PF08047 Family 2 216 15.90 96 100.00 Changed Histidine operon leader peptide
His_Phos_1 PF00300 Domain 385 104359 155.00 21 73.85 Changed Histidine phosphatase superfamily (branch 1)
His_Phos_2 PF00328 Family 43 11944 315.90 21 67.20 Changed Histidine phosphatase superfamily (branch 2)
HIT PF01230 Domain 25 33488 95.80 30 66.97 Changed HIT domain
Hjc PF01870 Family 11 381 92.80 31 63.87 Changed Archaeal holliday junction resolvase (hjc)
HJURP_C PF12347 Domain 37 544 64.00 38 14.83 Changed Holliday junction regulator protein family C-terminal repeat
HJURP_mid PF12346 Domain 15 45 109.10 59 17.59 Changed Holliday junction recognition protein-associated repeat
HK PF02110 Domain 8 12653 242.80 46 90.93 Changed Hydroxyethylthiazole kinase family
HK97-gp10_like PF04883 Family 59 11703 84.10 26 63.81 Changed Bacteriophage HK97-gp10, putative tail-component
HK_sensor PF16750 Domain 28 712 108.90 46 24.37 New Sensor domain of 2-component histidine kinase
HLH PF00010 Domain 149 22320 53.70 29 14.58 Changed Helix-loop-helix DNA-binding domain
HlyC PF02794 Family 24 1466 122.00 39 76.77 Changed RTX toxin acyltransferase family
HlyD PF00529 Family 46 20871 322.50 19 84.76 Changed HlyD membrane-fusion protein of T1SS
HlyD_2 PF12700 Family 1 237 205.00 92 95.22 Changed HlyD family secretion protein
HlyD_3 PF13437 Family 70 47218 115.80 18 31.72 Changed HlyD family secretion protein
HlyD_D23 PF16576 Domain 165 72553 202.60 17 53.38 New Barrel-sandwich domain of CusB or HlyD membrane-fusion
HlyD_D4 PF16572 Domain 5 3489 55.90 63 12.89 New Long alpha hairpin domain of cation efflux system protein, CusB
HlyE PF06109 Family 2 1904 210.20 85 91.46 Changed Haemolysin E (HlyE)
HlyIII PF03006 Family 38 19322 200.60 35 83.71 Changed Haemolysin-III related
HlyU PF10115 Family 34 770 91.80 52 96.67 Changed Transcriptional activator HlyU
HMA PF00403 Domain 51 75002 60.50 28 16.00 Changed Heavy-metal-associated domain
HMD PF03201 Family 16 71 96.80 48 28.13 Changed H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase
HMG-CoA_red PF00368 Family 281 8741 361.60 47 74.88 Changed Hydroxymethylglutaryl-coenzyme A reductase
HMG14_17 PF01101 Family 75 674 80.30 53 73.43 Changed HMG14 and HMG17
HMGL-like PF00682 Domain 15 53468 264.40 25 46.53 Changed HMGL-like
HMG_box PF00505 Domain 27 13187 66.60 28 18.22 Changed HMG (high mobility group) box
HMG_box_2 PF09011 Domain 9 1750 70.20 33 18.29 Changed HMG-box domain
HMG_box_5 PF14887 Family 3 139 83.20 72 13.12 Changed HMG (high mobility group) box 5
HMG_CoA_synt_C PF08540 Domain 7 14017 126.30 29 56.36 Changed Hydroxymethylglutaryl-coenzyme A synthase C terminal
HMG_CoA_synt_N PF01154 Domain 3 7625 166.10 59 41.45 Changed Hydroxymethylglutaryl-coenzyme A synthase N terminal
HMMR_C PF15908 Family 8 195 136.20 37 14.63 New Hyaluronan mediated motility receptor C-terminal
HMMR_N PF15905 Family 14 135 249.50 44 43.02 New Hyaluronan mediated motility receptor N-terminal
HmuY PF14064 Family 46 893 164.00 24 69.46 Changed HmuY protein
HN PF00423 Family 7 3653 440.40 33 93.85 Changed Haemagglutinin-neuraminidase
HNF-1A_C PF04813 Family 6 69 81.50 60 14.59 Changed Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus
HNF-1B_C PF04812 Family 13 198 215.20 57 41.93 Changed Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus
HNF-1_N PF04814 Family 22 389 159.70 42 35.76 Changed Hepatocyte nuclear factor 1 (HNF-1), N terminus
HNF_C PF09354 Domain 17 268 62.60 45 15.18 Changed HNF3 C-terminal domain
HNH PF01844 Family 46 33198 47.60 29 24.47 Changed HNH endonuclease
HNHc_6 PF16784 Family 2 4705 187.00 64 89.56 New Putative HNHc nuclease
HNH_2 PF13391 Domain 197 5235 60.80 35 19.19 Changed HNH endonuclease
HNH_3 PF13392 Domain 225 4543 45.30 28 24.34 Changed HNH endonuclease
HNH_4 PF13395 Domain 37 2293 52.90 37 5.60 Changed HNH endonuclease
HNH_5 PF14279 Domain 15 383 68.20 46 23.24 Changed HNH endonuclease
hNIFK_binding PF12196 Domain 25 102 38.20 64 14.10 Changed FHA Ki67 binding domain of hNIFK
HNOB PF07700 Domain 184 1441 152.90 24 34.22 Changed Haem-NO-binding
HNOBA PF07701 Domain 69 1532 126.20 28 18.55 Changed Heme NO binding associated
HnRNPA1 PF11627 Family 36 290 36.20 76 13.31 Changed Nuclear factor hnRNPA1
HnRNP_M PF11532 Family 4 85 29.50 86 4.67 Changed Heterogeneous nuclear ribonucleoprotein M
HOASN PF14515 Domain 2 410 89.10 68 26.86 Changed Haem-oxygenase-associated N-terminal helices
HobA PF12163 Domain 20 484 178.00 58 99.73 Changed DNA replication regulator
HOIP-UBA PF16678 Domain 28 149 142.10 40 9.70 New UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase
HOK_GEF PF01848 Family 18 12313 41.50 47 76.07 Changed Hok/gef family
Holin_2-3 PF13272 Family 16 728 90.50 68 86.90 Changed Putative 2/3 transmembrane domain holin
Holin_9 PF16936 Family 7 1736 77.70 94 97.61 New Putative holin
Holin_BhlA PF10960 Family 16 510 67.90 31 88.33 Changed BhlA holin family
Holin_BlyA PF05102 Family 3 99 59.40 51 94.24 Changed holin, BlyA family
Holin_SPP1 PF04688 Family 22 4930 69.50 61 73.14 Changed SPP1 phage holin
Hol_Tox PF16935 Family 4 1259 44.80 42 96.41 New Putative Holin-like Toxin (Hol-Tox)
Homeobox PF00046 Domain 157 35751 54.80 35 16.49 Changed Homeobox domain
Homeobox_KN PF05920 Family 73 5865 39.70 51 10.61 Changed Homeobox KN domain
Homez PF11569 Family 4 217 48.90 45 6.61 Changed Homeodomain leucine-zipper encoding, Homez
Homoserine_dh PF00742 Domain 968 24409 183.70 39 34.02 Changed Homoserine dehydrogenase
Hom_end PF05204 Domain 24 332 103.60 27 14.17 Changed Homing endonuclease
Hom_end_hint PF05203 Domain 24 538 190.90 36 24.66 Changed Hom_end-associated Hint
HOOK PF05622 Family 21 984 504.40 23 58.91 Changed HOOK protein
HopJ PF08888 Domain 63 1434 106.40 59 93.88 Changed HopJ type III effector protein
HopW1-1 PF15457 Family 5 67 298.00 67 38.95 Changed Type III T3SS secreted effector HopW1-1/HopPmaA
HORMA PF02301 Domain 139 1635 185.00 20 58.53 Changed HORMA domain
Hormone_1 PF00103 Domain 13 1700 160.50 33 93.44 Changed Somatotropin hormone family
Hormone_2 PF00123 Family 46 1075 27.60 40 32.48 Changed Peptide hormone
Hormone_3 PF00159 Family 19 354 34.80 63 37.73 Changed Pancreatic hormone peptide
Hormone_4 PF00220 Family 4 245 9.00 84 7.01 Changed Neurohypophysial hormones, N-terminal Domain
Hormone_5 PF00184 Family 31 278 76.60 61 54.57 Changed Neurohypophysial hormones, C-terminal Domain
Hormone_6 PF00236 Domain 12 233 91.80 66 80.82 Changed Glycoprotein hormone
Hormone_recep PF00104 Domain 342 9809 179.50 19 39.16 Changed Ligand-binding domain of nuclear hormone receptor
Host_attach PF10116 Family 115 883 130.00 24 84.18 Changed Protein required for attachment to host cells
Hox9_act PF04617 Family 48 458 165.30 35 67.39 Changed Hox9 activation region
HoxA13_N PF12284 Family 24 502 109.00 41 44.86 Changed Hox protein A13 N terminal
HpaB PF03241 Family 151 3956 196.80 43 40.33 Changed 4-hydroxyphenylacetate 3-hydroxylase C terminal
HpaB_N PF11794 Family 163 3973 255.40 50 52.44 Changed 4-hydroxyphenylacetate 3-hydroxylase N terminal
HpaP PF09483 Family 8 147 175.10 38 79.67 Changed Type III secretion protein (HpaP)
HpcH_HpaI PF03328 Family 19 31768 211.90 27 78.06 Changed HpcH/HpaI aldolase/citrate lyase family
HPD PF05044 Domain 21 292 133.50 63 22.11 Changed Homeo-prospero domain
Hph PF13694 Family 6 55 174.20 42 32.36 Changed Sec63/Sec62 complex-interacting family
HPHLAWLY PF14925 Family 15 65 473.80 38 70.18 Changed Domain of unknown function
HPIH PF13323 Family 76 253 148.80 33 13.63 Changed N-terminal domain with HPIH motif
HPIP PF15226 Family 7 64 101.20 58 66.43 Changed HCF-1 beta-propeller-interacting protein family
HPP PF04982 Family 365 3389 121.00 40 41.25 Changed HPP family
HPPK PF01288 Domain 1134 20195 126.60 41 69.15 Changed 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
Hpre_diP_synt_I PF07456 Family 41 1972 144.50 45 79.24 Changed Heptaprenyl diphosphate synthase component I
Hpr_kinase_C PF07475 Domain 59 9653 164.20 58 54.79 Changed HPr Serine kinase C-terminal domain
Hpr_kinase_N PF02603 Family 372 8671 124.50 50 40.03 Changed HPr Serine kinase N terminus
HPS3_C PF14763 Domain 15 101 290.80 53 33.19 Changed Hermansky-Pudlak syndrome 3, C-terminal
HPS3_Mid PF14762 Domain 19 139 338.90 39 35.96 Changed Hermansky-Pudlak syndrome 3, middle region
HPS3_N PF14761 Domain 25 151 190.00 33 17.94 Changed Hermansky-Pudlak syndrome 3
HPS6 PF15702 Family 14 68 658.40 49 90.98 New Hermansky-Pudlak syndrome 6 protein
Hpt PF01627 Family 241 42599 92.40 20 12.76 Changed Hpt domain
HPTransfase PF10090 Family 71 735 178.10 46 84.55 Changed Histidine phosphotransferase
HpuA PF16960 Family 5 171 301.50 73 92.87 New Haemoglobin-haptoglobin utilisation, porphyrin transporter
HP_OMP PF01856 Family 27 10754 164.70 29 40.83 Changed Helicobacter outer membrane protein
HP_OMP_2 PF02521 Domain 29 2253 450.20 39 97.20 Changed Putative outer membrane protein
HR1 PF02185 Family 218 1862 65.60 25 12.11 Changed Hr1 repeat
HrcA PF01628 Family 738 12276 216.70 33 64.35 Changed HrcA protein C terminal domain
HrcA_DNA-bdg PF03444 Family 13 2409 75.30 43 22.81 Changed Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HRCT1 PF15758 Family 7 20 77.80 64 71.23 New Histidine-rich carboxyl terminus protein 1
HRDC PF00570 Domain 123 26270 67.50 31 12.31 Changed HRDC domain
HRG PF16954 Family 46 190 55.30 28 58.44 New Haem-transporter, endosomal/lysosomal, haem-responsive gene
HRI1 PF16815 Domain 62 227 234.50 27 83.34 New Protein HRI1
HRM PF02793 Family 127 2468 65.30 29 9.34 Changed Hormone receptor domain
HrpA_pilin PF09589 Family 6 149 129.60 40 97.04 Changed HrpA pilus formation protein
HrpB1_HrpK PF09613 Family 8 299 155.50 31 94.31 Changed Bacterial type III secretion protein (HrpB1_HrpK)
HrpB2 PF09487 Family 8 152 114.10 40 86.97 Changed Bacterial type III secretion protein (HrpB2)
HrpB4 PF09502 Family 7 150 202.90 38 93.63 Changed Bacterial type III secretion protein (HrpB4)
HrpB7 PF09486 Family 8 148 150.50 37 91.70 Changed Bacterial type III secretion protein (HrpB7)
HrpB_C PF08482 Family 270 5459 131.60 62 17.10 Changed ATP-dependent helicase C-terminal
HrpE PF06188 Family 4 419 171.80 30 85.02 Changed HrpE/YscL/FliH and V-type ATPase subunit E
HrpF PF06266 Family 8 137 73.50 45 97.90 Changed HrpF protein
HrpJ PF07201 Domain 36 3717 161.30 28 46.17 Changed HrpJ-like domain
Hrs_helical PF12210 Domain 23 181 92.50 60 12.85 Changed Hepatocyte growth factor-regulated tyrosine kinase substrate
HRXXH PF13933 Domain 25 178 228.00 37 79.22 Changed Putative peptidase family
HR_lesion PF05514 Family 7 215 127.90 46 76.07 Changed HR-like lesion-inducing
Hs1pro-1_C PF07014 Family 14 78 253.10 53 57.04 Changed Hs1pro-1 protein C-terminus
Hs1pro-1_N PF07231 Family 10 67 175.40 46 38.24 Changed Hs1pro-1 N-terminus
HS1_rep PF02218 Repeat 103 1438 34.50 58 33.20 Changed Repeat in HS1/Cortactin
HSA PF07529 Domain 181 1614 67.20 24 4.18 Changed HSA
hSac2 PF12456 Family 92 567 108.00 28 15.13 Changed Inositol phosphatase
HsbA PF12296 Family 242 578 119.30 18 54.53 Changed Hydrophobic surface binding protein A
HSBP1 PF06825 Family 69 538 48.20 43 46.65 Changed Heat shock factor binding protein 1
HSCB_C PF07743 Domain 345 6140 75.40 44 41.88 Changed HSCB C-terminal oligomerisation domain
HSD3 PF15244 Family 15 133 279.80 42 64.82 Changed Spermatogenesis-associated protein 7, or HSD3
HsdM_N PF12161 Domain 140 21678 139.30 29 27.27 Changed HsdM N-terminal domain
HSDR_N PF04313 Family 77 14958 183.20 26 19.45 Changed Type I restriction enzyme R protein N terminus (HSDR_N)
HSDR_N_2 PF13588 Domain 41 3906 108.40 25 20.47 Changed Type I restriction enzyme R protein N terminus (HSDR_N)
HSF_DNA-bind PF00447 Family 465 3951 95.30 38 21.27 Changed HSF-type DNA-binding
hSH3 PF14603 Domain 20 214 82.20 44 15.20 Changed Helically-extended SH3 domain
HSL_N PF06350 Family 29 234 248.70 39 38.09 Changed Hormone-sensitive lipase (HSL) N-terminus
HSNSD PF12062 Family 26 446 385.90 58 55.18 Changed heparan sulfate-N-deacetylase
HSP20 PF00011 Family 25 32436 99.00 27 63.93 Changed Hsp20/alpha crystallin family
HSP33 PF01430 Family 637 14717 274.00 40 93.29 Changed Hsp33 protein
HSP70 PF00012 Family 28 69058 381.00 30 84.83 Changed Hsp70 protein
HSP90 PF00183 Family 116 15838 374.30 35 65.06 Changed Hsp90 protein
HSP9_HSP12 PF04119 Family 89 261 57.40 45 57.78 Changed Heat shock protein 9/12
HSV_VP16_C PF12149 Domain 2 31 29.80 83 6.06 Changed Herpes simplex virus virion protein 16 C terminal
HtaA PF04213 Family 94 912 155.90 29 45.89 Changed Htaa
HTHP PF11534 Family 18 82 69.30 53 83.36 Changed Hexameric tyrosine-coordinated heme protein (HTHP)
HTH_1 PF00126 Domain 1346 401538 59.80 32 20.01 Changed Bacterial regulatory helix-turn-helix protein, lysR family
HTH_10 PF04967 Domain 26 3369 52.70 38 15.40 Changed HTH DNA binding domain
HTH_11 PF08279 Domain 92 61454 55.00 27 13.16 Changed HTH domain
HTH_12 PF08461 Domain 9 4554 64.20 69 8.23 Changed Ribonuclease R winged-helix domain
HTH_13 PF11972 Domain 11 492 53.70 66 15.18 Changed HTH DNA binding domain
HTH_15 PF12324 Domain 7 312 72.40 52 33.56 Changed Helix-turn-helix domain of alkylmercury lyase
HTH_16 PF12645 Domain 52 3130 62.90 45 82.32 Changed Helix-turn-helix domain
HTH_17 PF12728 Domain 239 29488 50.30 24 39.58 Changed Helix-turn-helix domain
HTH_18 PF12833 Domain 327 267537 79.50 25 23.46 Changed Helix-turn-helix domain
HTH_19 PF12844 Domain 148 61967 62.70 22 35.22 Changed Helix-turn-helix domain
HTH_20 PF12840 Domain 88 26921 61.80 28 38.83 Changed Helix-turn-helix domain
HTH_21 PF13276 Domain 220 41233 58.60 26 24.60 Changed HTH-like domain
HTH_22 PF13309 Domain 221 7707 60.80 43 26.88 Changed HTH domain
HTH_23 PF13384 Domain 194 12113 45.50 26 27.76 Changed Homeodomain-like domain
HTH_24 PF13412 Domain 364 61248 47.00 32 23.31 Changed Winged helix-turn-helix DNA-binding
HTH_25 PF13413 Domain 139 13552 61.70 38 24.46 Changed Helix-turn-helix domain
HTH_26 PF13443 Domain 104 12400 60.30 26 58.97 Changed Cro/C1-type HTH DNA-binding domain
HTH_27 PF13463 Domain 30 7070 65.40 36 45.88 Changed Winged helix DNA-binding domain
HTH_28 PF13518 Domain 91 19425 49.80 23 29.69 Changed Helix-turn-helix domain
HTH_29 PF13551 Domain 81 6187 59.80 29 21.60 Changed Winged helix-turn helix
HTH_3 PF01381 Domain 175 167775 53.70 23 30.64 Changed Helix-turn-helix
HTH_30 PF13556 Domain 341 27510 58.30 32 13.88 Changed PucR C-terminal helix-turn-helix domain
HTH_31 PF13560 Domain 111 23535 64.50 25 31.60 Changed Helix-turn-helix domain
HTH_32 PF13565 Domain 474 4152 78.40 26 33.58 Changed Homeodomain-like domain
HTH_33 PF13592 Domain 83 2789 56.70 25 27.63 Changed Winged helix-turn helix
HTH_34 PF13601 Domain 22 1081 79.40 33 74.26 Changed Winged helix DNA-binding domain
HTH_35 PF13693 Domain 37 5548 73.70 64 83.19 Changed Winged helix-turn-helix DNA-binding
HTH_36 PF13730 Domain 58 6949 53.80 27 20.16 Changed Helix-turn-helix domain
HTH_37 PF13744 Domain 28 7418 81.90 32 78.36 Changed Helix-turn-helix domain
HTH_38 PF13936 Domain 68 15122 42.50 40 16.62 Changed Helix-turn-helix domain
HTH_39 PF14090 Domain 22 943 66.60 38 46.20 Changed Helix-turn-helix domain
HTH_40 PF14493 Domain 290 7468 89.00 44 21.02 Changed Helix-turn-helix domain
HTH_41 PF14502 Family 7 1679 47.90 86 16.30 Changed Helix-turn-helix domain
HTH_42 PF06224 Family 84 6267 327.40 38 78.54 Changed Winged helix DNA-binding domain
HTH_43 PF09904 Family 24 995 88.30 51 92.54 Changed Winged helix-turn helix
HTH_44 PF14641 Domain 53 524 123.40 29 8.35 Changed Helix-turn-helix DNA-binding domain of SPT6
HTH_45 PF14947 Domain 19 481 76.20 24 69.63 Changed Winged helix-turn-helix
HTH_46 PF15977 Family 24 5593 68.10 56 31.81 New Winged helix-turn-helix DNA binding
HTH_47 PF16221 Domain 19 386 76.50 49 17.84 New winged helix-turn-helix
HTH_5 PF01022 Domain 38 55682 46.90 34 34.38 Changed Bacterial regulatory protein, arsR family
HTH_6 PF01418 Domain 10 51799 75.80 28 27.32 Changed Helix-turn-helix domain, rpiR family
HTH_7 PF02796 Domain 14 19060 44.90 31 24.03 Changed Helix-turn-helix domain of resolvase
HTH_8 PF02954 Domain 59 69331 40.90 33 9.18 Changed Bacterial regulatory protein, Fis family
HTH_9 PF08221 Domain 17 495 60.80 30 10.84 Changed RNA polymerase III subunit RPC82 helix-turn-helix domain
HTH_AraC PF00165 Domain 55 921 37.20 33 20.83 Changed Bacterial regulatory helix-turn-helix proteins, AraC family
HTH_AsnC-type PF13404 Domain 238 7917 42.00 34 25.81 Changed AsnC-type helix-turn-helix domain
HTH_CodY PF08222 Domain 3 7004 60.80 83 23.56 Changed CodY helix-turn-helix domain
HTH_Crp_2 PF13545 Domain 94 28569 71.50 23 30.93 Changed Crp-like helix-turn-helix domain
HTH_DeoR PF08220 Domain 15 72424 55.90 34 21.57 Changed DeoR-like helix-turn-helix domain
HTH_IclR PF09339 Domain 84 51173 51.30 28 19.34 Changed IclR helix-turn-helix domain
HTH_Mga PF08280 Domain 16 3195 58.40 23 12.63 Changed M protein trans-acting positive regulator (MGA) HTH domain
HTH_micro PF17007 Family 5 18 357.70 27 46.34 New HTH-like
HTH_OrfB_IS605 PF12323 Family 123 18377 44.70 38 12.35 Changed Helix-turn-helix domain
HTH_psq PF05225 Domain 14 2086 43.30 27 11.39 Changed helix-turn-helix, Psq domain
HTH_Tnp_1 PF01527 Family 28 58544 73.10 22 68.98 Changed Transposase
HTH_Tnp_1_2 PF13022 Domain 4 71 135.80 32 97.54 Changed Helix-turn-helix of insertion element transposase
HTH_Tnp_4 PF13613 Domain 81 3131 50.30 45 29.96 Changed Helix-turn-helix of DDE superfamily endonuclease
HTH_Tnp_IS1 PF12759 Domain 3 6577 41.10 72 52.01 Changed InsA C-terminal domain
HTH_Tnp_IS630 PF01710 Domain 5 2446 99.70 41 77.14 Changed Transposase
HTH_Tnp_ISL3 PF13542 Domain 131 8470 51.10 29 15.15 Changed Helix-turn-helix domain of transposase family ISL3
HTH_Tnp_Mu_1 PF02316 Family 4 1232 112.30 22 27.53 Changed Mu DNA-binding domain
HTH_Tnp_Mu_2 PF09039 Domain 5 430 101.40 30 20.48 Changed Mu DNA binding, I gamma subdomain
HTH_Tnp_Tc3_1 PF11427 Family 2 360 47.00 33 25.88 Changed Tc3 transposase
HTH_Tnp_Tc3_2 PF01498 Family 25 1799 66.30 23 23.67 Changed Transposase
HTH_Tnp_Tc5 PF03221 Domain 157 3570 63.10 21 13.91 Changed Tc5 transposase DNA-binding domain
HTH_WhiA PF02650 Domain 361 10295 84.20 55 26.91 Changed WhiA C-terminal HTH domain
HtrL_YibB PF09612 Family 8 1116 253.20 75 88.72 Changed Bacterial protein of unknown function (HtrL_YibB)
HTS PF04204 Domain 65 6945 292.50 57 96.10 Changed Homoserine O-succinyltransferase
HU-DNA_bdg PF14848 Domain 17 712 118.00 34 54.43 Changed DNA-binding domain
Humanin PF15040 Family 8 24 24.00 74 95.68 Changed Humanin family
Hum_adeno_E3A PF05393 Family 2 90 97.60 43 41.56 Changed Human adenovirus early E3A glycoprotein
HUN PF08729 Domain 47 623 50.20 39 6.60 Changed HPC2 and ubinuclein domain
HupE_UreJ PF04955 Family 49 1889 177.00 41 91.91 Changed HupE / UreJ protein
HupE_UreJ_2 PF13795 Family 54 1175 143.40 36 53.95 Changed HupE / UreJ protein
HupF_HypC PF01455 Family 437 8707 69.60 54 78.35 Changed HupF/HypC family
HupH_C PF04809 Family 56 7084 108.90 40 72.75 Changed HupH hydrogenase expression protein, C-terminal conserved region
Hus1 PF04005 Family 27 651 282.20 22 89.10 Changed Hus1-like protein
HutD PF05962 Family 69 4845 173.20 39 90.03 Changed HutD
HutP PF09021 Domain 63 571 131.30 43 90.70 Changed HutP
HVSL PF09749 Family 111 554 219.80 22 77.95 Changed Uncharacterised conserved protein
HV_small_capsid PF17086 Family 1 30 73.30 48 86.95 New Small capsid protein of Herpesviridae
HWE_HK PF07536 Domain 42 2585 82.20 33 15.09 Changed HWE histidine kinase
HxlR PF01638 Family 13 36146 88.60 33 67.49 Changed HxlR-like helix-turn-helix
HXXEE PF13787 Family 97 1656 112.50 25 64.22 Changed Protein of unknown function with HXXEE motif
HxxPF_rpt PF13745 Domain 759 25451 92.90 30 5.09 Changed HxxPF-repeated domain
HXXSHH PF07586 Family 104 458 299.20 24 68.00 Changed Protein of unknown function (DUF1552)
HyaE PF07449 Family 7 3543 106.10 66 79.47 Changed Hydrogenase-1 expression protein HyaE
Hyaluronidase_1 PF07212 Family 2 414 257.30 78 79.53 Changed Hyaluronidase protein (HylP)
HycA_repressor PF11046 Family 9 2993 145.50 90 95.30 Changed Transcriptional repressor of hyc and hyp operons
Hyccin PF09790 Family 31 377 282.00 34 63.52 Changed Hyccin
HycH PF07450 Family 27 4504 129.10 72 94.64 Changed Formate hydrogenlyase maturation protein HycH
HycI PF01750 Domain 19 11167 127.00 37 73.28 Changed Hydrogenase maturation protease
Hydantoinase_A PF01968 Family 32 7702 266.10 34 30.68 Changed Hydantoinase/oxoprolinase
Hydantoinase_B PF02538 Family 412 5457 499.00 42 52.54 Changed Hydantoinase B/oxoprolinase
Hydant_A_N PF05378 Family 43 7411 176.40 32 20.05 Changed Hydantoinase/oxoprolinase N-terminal region
Hydrolase PF00702 Domain 229 137966 225.00 23 33.94 Changed haloacid dehalogenase-like hydrolase
Hydrolase_2 PF07486 Family 476 4787 104.00 31 41.18 Changed Cell Wall Hydrolase
Hydrolase_3 PF08282 Domain 66 95943 233.30 22 88.84 Changed haloacid dehalogenase-like hydrolase
Hydrolase_4 PF12146 Family 95 42261 227.80 19 70.50 Changed Serine aminopeptidase, S33
Hydrolase_6 PF13344 Domain 148 18937 101.20 34 35.62 Changed Haloacid dehalogenase-like hydrolase
Hydrolase_like PF13242 Domain 153 40384 72.10 28 27.70 Changed HAD-hyrolase-like
Hydrophobin PF01185 Family 199 861 80.60 32 57.61 Changed Fungal hydrophobin
Hydrophobin_2 PF06766 Family 87 288 64.00 45 40.44 Changed Fungal hydrophobin
Hydrophob_seed PF14547 Domain 19 1054 81.70 50 52.14 Changed Hydrophobic seed protein
Hyd_WA PF06462 Family 211 1419 30.90 34 13.50 Changed Propeller
HYLS1_C PF15311 Family 20 122 78.40 41 27.31 Changed Hydrolethalus syndrome protein 1 C-terminus
HypA PF01155 Domain 501 8563 112.10 48 97.31 Changed Hydrogenase/urease nickel incorporation, metallochaperone, hypA
HypD PF01924 Family 330 5020 342.10 63 95.45 Changed Hydrogenase formation hypA family
Hyphal_reg_CWP PF11765 Domain 73 263 298.30 28 38.29 Changed Hyphally regulated cell wall protein N-terminal
Hypoth_Ymh PF09509 Family 48 703 119.00 33 39.20 Changed Protein of unknown function (Hypoth_ymh)
HYR PF02494 Domain 13 2317 80.40 29 13.39 Changed HYR domain
Hyr1 PF15789 Repeat 17 412 43.00 53 37.01 New Hyphally regulated cell wall GPI-anchored protein 1
H_kinase_N PF12282 Family 89 3124 144.80 48 29.54 Changed Signal transduction histidine kinase
H_lectin PF09458 Domain 181 600 66.60 22 20.32 Changed H-type lectin domain
H_PPase PF03030 Family 330 3474 599.40 44 93.70 Changed Inorganic H+ pyrophosphatase
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