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Browse Pfam families

New Top twenty Numbers A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
ID Accession Type Number of sequences Average length Average %id Average coverage Has 3D Change status Description
Seed Full
I-EGF_1 PF18372 Domain 145 1053 29.50 45 3.32 New Integrin beta epidermal growth factor like domain 1
I-set PF07679 Domain 48 138529 88.80 21 25.76 Changed Immunoglobulin I-set domain
IalB PF06776 Family 45 1576 134.00 24 66.56 Changed Invasion associated locus B (IalB) protein
IATP PF04568 Family 7 1025 85.30 27 71.88 Changed Mitochondrial ATPase inhibitor, IATP
IAT_beta PF11924 Domain 35 523 241.90 25 28.99 Changed Inverse autotransporter, beta-domain
IBB PF01749 Family 188 2811 86.40 33 16.72 Changed Importin beta binding domain
IBD PF10416 Domain 94 255 121.30 21 41.30 Changed Transcription-initiator DNA-binding domain IBD
IBN_N PF03810 Family 52 10702 72.30 20 7.46 Changed Importin-beta N-terminal domain
IBP39 PF11422 Family 7 21 175.70 26 48.39 Changed Initiator binding protein 39 kDa
IBR PF01485 Domain 160 16126 64.60 23 17.27 Changed IBR domain, a half RING-finger domain
Ibs_toxin PF13956 Family 4 5 18.80 74 100.00 Changed Toxin Ibs, type I toxin-antitoxin system
IBV_3A PF03617 Family 1 6 57.00 80 100.00 Changed IBV 3A protein
IBV_3B PF03622 Family 1 7 63.90 60 96.54 Changed IBV 3B protein
IBV_3C PF03620 Family 1 7 91.90 73 90.56 Changed IBV 3C protein
ICA69 PF04629 Domain 23 465 166.30 28 45.28 Changed Islet cell autoantigen ICA69, C-terminal domain
ICAM_N PF03921 Domain 5 352 89.50 32 19.49 Changed Intercellular adhesion molecule (ICAM), N-terminal domain
ICAP-1_inte_bdg PF10480 Family 2 207 158.30 61 83.16 Changed Beta-1 integrin binding protein
ICAT PF06384 Family 19 319 72.20 42 41.58 Changed Beta-catenin-interacting protein ICAT
ICE2 PF08426 Family 60 562 351.30 34 92.38 Changed ICE2
ICEA PF05315 Family 3 26 176.00 36 82.05 Changed ICEA Protein
IceA2 PF05862 Family 2 4 51.80 31 108.38 Changed Helicobacter pylori IceA2 protein
Ice_nucleation PF00818 Repeat 4 171 15.00 74 26.07 Changed Ice nucleation protein repeat
ICL PF00463 Domain 6 8020 237.60 25 90.38 Changed Isocitrate lyase family
IclR PF01614 Family 20 24379 122.80 23 46.89 Changed Bacterial transcriptional regulator
IcmF-related PF06761 Family 127 1476 301.60 22 26.91 Changed Intracellular multiplication and human macrophage-killing
IcmF_C PF06744 Family 143 1449 197.40 24 17.49 Changed Type VI secretion protein IcmF C-terminal
ICMT PF04140 Family 12 3631 91.10 26 38.13 Changed Isoprenylcysteine carboxyl methyltransferase (ICMT) family
ID PF18543 Domain 14 42 54.10 36 9.72 New Intracellular delivery domain
IDEAL PF08858 Domain 63 1055 35.30 33 27.66 Changed IDEAL domain
IDH PF03971 Family 182 2521 715.30 62 98.42 Changed Monomeric isocitrate dehydrogenase
IDO PF01231 Family 188 2063 361.00 25 71.26 Changed Indoleamine 2,3-dioxygenase
IER PF05760 Family 20 294 188.80 23 85.18 Changed Immediate early response protein (IER)
IES5 PF17335 Family 11 36 106.00 38 86.81 Changed Ino80 complex subunit 5
IF-2 PF11987 Domain 612 10822 105.20 37 12.47 Changed Translation-initiation factor 2
IF-2B PF01008 Family 18 8819 279.70 26 73.81 Changed Initiation factor 2 subunit family
IF2_assoc PF08364 Family 95 2292 39.10 40 4.46 Changed Bacterial translation initiation factor IF-2 associated region
IF2_N PF04760 Domain 101 11075 51.70 27 8.66 Changed Translation initiation factor IF-2, N-terminal region
IF3_C PF00707 Domain 566 8726 85.70 40 46.32 Changed Translation initiation factor IF-3, C-terminal domain
IF3_N PF05198 Domain 544 8389 65.00 48 34.65 Changed Translation initiation factor IF-3, N-terminal domain
IF4E PF01652 Domain 298 3946 159.60 31 57.81 Changed Eukaryotic initiation factor 4E
Ifi-6-16 PF06140 Family 63 1046 74.20 34 40.20 Changed Interferon-induced 6-16 family
IFN-gamma PF00714 Domain 15 109 138.70 43 82.02 Changed Interferon gamma
IFNGR1 PF07140 Family 7 67 149.90 35 36.53 Changed Interferon gamma receptor (IFNGR1)
IFP_35_N PF07334 Family 5 114 73.60 37 23.95 Changed Interferon-induced 35 kDa protein (IFP 35) N-terminus
IFR3_antag PF14754 Domain 1 1 249.00 100 7.84 Changed Papain-like auto-proteinase
IFRD PF05004 Family 79 1350 277.60 24 66.26 Changed Interferon-related developmental regulator (IFRD)
IFRD_C PF04836 Family 45 568 52.00 44 11.95 Changed Interferon-related protein conserved region
IFS PF16718 Domain 11 13 155.90 30 86.00 Changed Immunity factor for SPN
IFT20 PF14931 Family 48 422 107.60 40 83.11 Changed Intraflagellar transport complex B, subunit 20
IFT43 PF15305 Family 18 330 125.60 35 61.52 Changed Intraflagellar transport protein 43
IFT46_B_C PF12317 Family 50 518 190.30 43 57.77 Changed Intraflagellar transport complex B protein 46 C terminal
IFT57 PF10498 Family 50 551 296.30 35 79.06 Changed Intra-flagellar transport protein 57
IFT81_CH PF18383 Domain 24 402 117.20 43 18.07 New Intraflagellar transport 81 calponin homology domain
ig PF00047 Domain 34 8595 83.70 17 11.43 Changed Immunoglobulin domain
IgaA PF07095 Family 16 169 626.30 41 96.32 Changed Intracellular growth attenuator protein IgaA
IGF2_C PF08365 Family 11 118 51.90 60 26.12 Changed Insulin-like growth factor II E-peptide
IGFBP PF00219 Domain 218 2019 54.80 42 17.11 Changed Insulin-like growth factor binding protein
IGFL PF14653 Family 12 95 78.50 54 64.53 Changed Insulin growth factor-like family
IgGFc_binding PF17517 Family 359 1596 299.50 21 29.46 Changed IgGFc binding protein
IgG_binding_B PF01378 Domain 3 14 55.30 49 14.69 Changed B domain
IglC PF11550 Family 1 4 210.20 59 99.76 Changed Intracellular growth locus C protein
IGPD PF00475 Family 579 7255 143.10 49 61.70 Changed Imidazoleglycerol-phosphate dehydratase
IGPS PF00218 Domain 17 7614 249.50 39 76.81 Changed Indole-3-glycerol phosphate synthase
IGR PF09597 Domain 89 669 55.60 40 29.50 Changed IGR protein motif
Ig_2 PF13895 Domain 40 11092 85.80 18 16.37 Changed Immunoglobulin domain
Ig_3 PF13927 Domain 990 54660 78.00 22 14.65 Changed Immunoglobulin domain
Ig_4 PF16680 Domain 59 185 73.00 37 42.09 Changed T-cell surface glycoprotein CD3 delta chain
Ig_5 PF16681 Domain 21 122 77.40 39 30.25 Changed Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain
Ig_6 PF18452 Domain 45 865 50.50 37 9.83 New Immunoglobulin domain
Ig_C17orf99 PF17736 Domain 7 295 87.60 26 22.83 New C17orf99 Ig domain
Ig_C19orf38 PF17737 Domain 8 54 89.40 55 32.11 New Ig domain in C19orf38 (HIDE1)
Ig_GlcNase PF18368 Domain 160 900 105.10 27 11.06 New Exo-beta-D-glucosaminidase Ig-fold domain
Ig_J_chain PF15097 Family 10 60 126.00 67 79.65 Changed Immunoglobulin J chain
Ig_mannosidase PF17753 Domain 250 1587 78.30 21 9.23 New Ig-fold domain
Ig_Tie2_1 PF10430 Domain 7 118 95.00 71 8.95 Changed Tie-2 Ig-like domain 1
IHABP4_N PF16174 Family 19 330 134.20 34 35.84 Changed Intracellular hyaluronan-binding protein 4 N-terminal
IHHNV_capsid PF16530 Domain 3 1 323.00 100 98.18 Changed Infectious hypodermal and haematopoietic necrosis virus, capsid
IHO1 PF15771 Family 16 109 304.50 55 88.61 Changed Interactor of HORMAD1 protein 1
IIGP PF05049 Family 6 878 253.50 27 67.09 Changed Interferon-inducible GTPase (IIGP)
IKBKB_SDD PF18397 Domain 13 331 252.00 58 37.30 New IQBAL scaffold dimerization domain
IKI3 PF04762 Family 24 1443 640.30 25 69.65 Changed IKI3 family
IKKbetaNEMObind PF12179 Domain 24 243 36.00 45 4.96 Changed I-kappa-kinase-beta NEMO binding domain
IL1 PF00340 Domain 13 668 114.60 26 57.09 Changed Interleukin-1 / 18
IL10 PF00726 Domain 3 308 155.90 26 87.35 Changed Interleukin 10
IL11 PF07400 Domain 11 80 159.50 43 84.50 Changed Interleukin 11
IL12 PF03039 Domain 8 127 155.70 42 84.53 Changed Interleukin-12 alpha subunit
IL12p40_C PF10420 Domain 38 166 86.30 40 25.31 Changed Cytokine interleukin-12p40 C-terminus
IL13 PF03487 Domain 16 52 121.90 62 70.27 Changed Interleukin-13
Il13Ra_Ig PF18001 Domain 9 63 92.70 59 20.69 New Interleukin-13 receptor subunit alpha Ig-like domain
IL15 PF02372 Domain 8 247 127.90 30 83.54 Changed Interleukin 15
IL17 PF06083 Family 100 876 79.80 33 44.78 Changed Interleukin-17
IL17R_D_N PF16742 Family 6 137 111.30 65 16.54 Changed N-terminus of interleukin 17 receptor D
IL17R_fnIII_D1 PF16556 Domain 11 217 145.70 38 22.46 Changed Interleukin-17 receptor, fibronectin-III-like domain 1
IL17R_fnIII_D2 PF16578 Domain 26 191 97.60 40 14.21 Changed Interleukin 17 receptor D
IL17_R_N PF15037 Family 12 324 281.60 27 59.49 Changed Interleukin-17 receptor extracellular region
IL1_propep PF02394 Family 33 149 100.30 36 37.31 Changed Interleukin-1 propeptide
IL2 PF00715 Domain 14 55 138.00 69 93.75 Changed Interleukin 2
IL22 PF14565 Domain 2 107 138.10 49 68.59 Changed Interleukin 22 IL-10-related T-cell-derived-inducible factor
IL23 PF16649 Domain 5 48 150.90 73 82.61 Changed Interleukin 23 subunit alpha
IL28A PF15177 Domain 28 168 134.30 42 76.67 Changed Interleukin-28A
IL2RB_N1 PF18707 Domain 25 94 89.30 34 16.99 New Interleukin-2 receptor subunit beta N-terminal domain 1
Il2rg PF15874 Family 29 225 89.10 30 19.99 Changed Putative Interleukin 2 receptor, gamma chain
IL3 PF02059 Domain 8 32 113.30 43 77.98 Changed Interleukin-3
IL31 PF15209 Family 9 34 128.80 45 78.49 Changed Interleukin 31
IL32 PF15225 Family 7 35 93.80 64 45.88 Changed Interleukin 32
IL33 PF15095 Family 10 93 173.10 55 96.16 Changed Interleukin 33
IL34 PF15036 Domain 13 94 144.30 57 71.79 Changed Interleukin 34
IL3Ra_N PF18611 Domain 25 109 73.70 35 21.82 New IL-3 receptor alpha chain N-terminal domain
IL4 PF00727 Domain 13 118 100.80 33 71.94 Changed Interleukin 4
IL4Ra_N PF09238 Domain 21 137 93.20 38 16.91 Changed Interleukin-4 receptor alpha chain, N-terminal
IL4_i_Ig PF18258 Domain 10 39 72.60 36 41.59 New Interleukin-4 inducing immunoglobulin-binding domain
IL5 PF02025 Domain 10 90 108.20 45 83.02 Changed Interleukin 5
IL6 PF00489 Domain 7 149 159.00 42 83.74 Changed Interleukin-6/G-CSF/MGF family
IL6Ra-bind PF09240 Domain 17 970 93.50 23 23.28 Changed Interleukin-6 receptor alpha chain, binding
IL7 PF01415 Family 18 134 103.30 46 81.89 Changed Interleukin 7/9 family
IL8 PF00048 Domain 237 3063 58.30 28 52.10 Changed Small cytokines (intecrine/chemokine), interleukin-8 like
Ilar_coat PF01787 Family 20 13 201.80 23 90.76 Changed Ilarvirus coat protein
ILEI PF15711 Domain 219 1692 88.20 29 15.98 Changed Interleukin-like EMT inducer
Ilm1 PF10311 Family 53 379 160.50 30 85.03 Changed Increased loss of mitochondrial DNA protein 1
IlvB_leader PF08049 Family 3 16 31.80 68 67.96 Changed IlvB leader peptide
IlvC PF01450 Family 295 8361 140.80 39 43.53 Changed Acetohydroxy acid isomeroreductase, catalytic domain
ILVD_EDD PF00920 Family 918 14456 515.80 39 90.09 Changed Dehydratase family
IlvGEDA_leader PF08046 Family 2 22 32.00 85 91.18 Changed IlvGEDA operon leader peptide
IlvN PF07991 Family 43 7621 163.70 47 45.22 Changed Acetohydroxy acid isomeroreductase, NADPH-binding domain
Ima1_N PF09779 Family 96 746 122.40 31 18.74 Changed Ima1 N-terminal domain
ImcF-related_N PF14331 Family 127 1446 254.80 28 22.31 Changed ImcF-related N-terminal domain
IMCp PF12314 Family 31 747 82.60 33 20.78 Changed Inner membrane complex protein
IMD PF08397 Family 5 1587 185.80 33 28.38 Changed IRSp53/MIM homology domain
Img2 PF05046 Domain 151 860 84.10 31 45.96 Changed Mitochondrial large subunit ribosomal protein (Img2)
IML1 PF12257 Family 105 1127 271.80 42 18.98 Changed Vacuolar membrane-associated protein Iml1
Imm-NTF2 PF15655 Family 7 98 127.70 25 58.75 Changed NTF2 fold immunity protein
Imm-NTF2-2 PF15631 Family 16 80 67.30 33 47.76 Changed NTF2 fold immunity protein
Imm1 PF14430 Family 34 327 119.60 17 83.48 Changed Immunity protein Imm1
Imm10 PF15588 Family 7 93 102.10 22 69.67 Changed Immunity protein 10
Imm12 PF15560 Family 2 12 132.60 37 85.35 Changed Immunity protein 12
Imm15 PF15561 Family 2 10 157.40 20 88.63 Changed Immunity protein 15
Imm17 PF15562 Family 31 158 59.20 29 73.09 Changed Immunity protein 17
Imm19 PF15563 Family 2 22 199.50 31 92.23 Changed Immunity protein 19
Imm2 PF14426 Family 1 2 60.00 35 50.21 Changed Immunity protein Imm2
Imm21 PF15589 Family 13 143 147.20 43 84.31 Changed Immunity protein 21
Imm25 PF15564 Family 2 6 130.80 53 66.41 Changed Immunity protein 25
Imm26 PF15428 Family 33 252 101.10 17 47.71 Changed Immunity protein 26
Imm27 PF15590 Family 9 31 62.80 30 55.68 Changed Immunity protein 27
Imm3 PF14425 Family 6 38 115.40 27 92.30 Changed Immunity protein Imm3
Imm30 PF15565 Family 5 63 97.30 30 59.94 Changed Immunity protein 30
Imm31 PF15591 Family 2 17 69.30 36 83.02 Changed Immunity protein 31
Imm32 PF15566 Family 4 20 53.60 32 61.42 Changed Immunity protein 32
Imm35 PF15567 Family 13 161 86.10 22 35.42 Changed Immunity protein 35
Imm39 PF15568 Family 2 7 123.40 29 95.79 Changed Immunity protein 39
Imm40 PF15569 Family 2 43 90.30 25 78.22 Changed Immunity protein 40
Imm41 PF15592 Family 5 42 111.30 21 83.48 Changed Immunity protein 41
Imm42 PF15593 Family 22 70 156.10 17 92.80 Changed Immunity protein 42
Imm43 PF15570 Family 7 35 120.00 21 56.84 Changed Immunity protein 43
Imm44 PF15571 Family 3 31 122.90 21 90.72 Changed Immunity protein 44
Imm45 PF15572 Family 5 38 94.60 35 73.16 Changed Immunity protein 45
Imm47 PF15573 Family 2 19 243.20 46 96.21 Changed Immunity protein 47
Imm48 PF15574 Family 8 19 124.80 31 89.78 Changed Immunity protein 48
Imm49 PF15575 Family 52 480 198.60 21 71.32 Changed Immunity protein 49
Imm5 PF14423 Family 12 57 173.40 21 53.62 Changed Immunity protein Imm5
Imm50 PF15594 Family 15 157 115.90 17 79.44 Changed Immunity protein 50
Imm51 PF15595 Family 19 214 101.20 28 60.34 Changed Immunity protein 51
Imm52 PF15579 Family 16 174 94.90 32 45.36 Changed Immunity protein 52
Imm53 PF15580 Family 20 154 89.90 35 85.06 Changed Immunity protein 53
Imm57 PF15596 Family 2 4 105.20 50 76.97 Changed Immunity protein 57
Imm58 PF15581 Family 2 7 105.40 35 97.11 Changed Immunity protein 58
Imm59 PF15597 Family 13 42 97.50 32 85.98 Changed Immunity protein 59
Imm6 PF14434 Family 10 78 116.60 26 70.40 Changed Immunity protein Imm6
Imm61 PF15598 Family 7 44 138.10 24 80.06 Changed Immunity protein 61
Imm63 PF15599 Family 12 91 83.40 23 48.92 Changed Immunity protein 63
Imm64 PF15600 Family 3 12 194.60 32 94.84 Changed Immunity protein 64
Imm65 PF15582 Family 1 6 260.70 43 92.27 Changed Immunity protein 65
Imm68 PF15583 Family 9 67 142.00 40 24.52 Changed Immunity protein 68
Imm7 PF15585 Family 10 77 125.70 36 97.03 Changed Immunity protein 7
Imm70 PF15601 Family 9 58 121.40 35 90.99 Changed Immunity protein 70
Imm71 PF15602 Family 7 37 141.70 28 42.27 Changed Immunity protein 71
Imm72 PF15584 Family 3 38 95.70 41 29.14 Changed Immunity protein 72
Imm74 PF15603 Family 9 46 75.40 24 91.15 Changed Immunity protein 74
Imm75 PF15660 Family 3 0 0.00 0 0.00 Changed Putative Immunity protein 75
Imm8 PF15586 Family 17 115 106.30 25 90.51 Changed Immunity protein 8
Imm9 PF15587 Family 3 39 140.80 31 90.63 Changed Immunity protein 9
ImmE5 PF11480 Family 3 15 76.50 37 74.98 Changed Colicin-E5 Imm protein
Imm_superinfect PF14373 Family 50 418 41.70 39 38.65 Changed Superinfection immunity protein
Imp-YgjV PF10688 Family 67 787 122.90 22 80.13 Changed Bacterial inner membrane protein
IMP2_C PF18591 Domain 7 52 62.70 45 34.08 New Immune Mapped Protein 2 (IMP2) C-terminal domain
IMP2_N PF18590 Domain 45 161 88.30 31 27.76 New Immune Mapped Protein 2 (IMP2) N-terminal domain
IMPa_helical PF18642 Domain 20 61 103.80 30 10.71 New Immunomodulating metalloprotease helical domain
ImpA_N PF06812 Family 135 1599 119.00 25 28.88 Changed ImpA, N-terminal, type VI secretion system
IMPa_N_2 PF18650 Domain 12 59 198.50 21 21.20 New Immunomodulating metalloprotease N-terminal domain
IMPDH PF00478 Domain 523 13377 411.50 37 92.63 Changed IMP dehydrogenase / GMP reductase domain
ImpE PF07024 Family 53 375 121.60 35 45.00 Changed ImpE protein
Importin_rep PF18773 Repeat 17 313 39.20 52 4.18 New Importin 13 repeat
Importin_rep_2 PF18786 Repeat 52 267 43.10 52 8.62 New Importin 13 repeat
Importin_rep_3 PF18806 Repeat 27 282 72.70 43 8.53 New Importin 13 repeat
Importin_rep_4 PF18808 Repeat 9 1407 91.80 35 8.90 New Importin repeat
Importin_rep_5 PF18816 Repeat 71 387 51.80 55 4.80 New Importin repeat
Importin_rep_6 PF18829 Repeat 6 707 110.90 34 10.41 New Importin repeat 6
IMP_cyclohyd PF07826 Domain 63 573 203.20 43 89.20 Changed IMP cyclohydrolase-like protein
IMS PF00817 Family 84 17662 153.60 29 31.11 Changed impB/mucB/samB family
IMS_C PF11799 Domain 851 14933 119.80 19 24.24 Changed impB/mucB/samB family C-terminal domain
IMS_HHH PF11798 Motif 75 5925 31.90 34 7.46 Changed IMS family HHH motif
IMUP PF15761 Family 8 36 96.40 52 89.34 Changed Immortalisation up-regulated protein
InaF-motif PF15018 Motif 32 303 34.80 46 17.39 Changed TRP-interacting helix
INCA1 PF15142 Family 13 48 151.80 62 59.08 Changed INCA1
IncD PF17628 Family 1 1 141.00 100 100.00 Changed Inclusion membrane protein D
IncE PF17627 Family 1 1 132.00 100 100.00 Changed Inclusion membrane protein E
INCENP_ARK-bind PF03941 Family 124 1127 56.70 31 5.71 Changed Inner centromere protein, ARK binding region
INCENP_N PF12178 Domain 14 123 35.50 55 4.25 Changed Chromosome passenger complex (CPC) protein INCENP N terminal
IncF PF17626 Family 1 1 104.00 100 100.00 Changed Inclusion membrane protein F
IncFII_repA PF02387 Family 6 73 245.20 24 88.47 Changed IncFII RepA protein family
Indigoidine_A PF04227 Family 283 2739 277.20 48 68.27 Changed Indigoidine synthase A like protein
ING PF12998 Domain 73 3027 98.50 22 24.24 Changed Inhibitor of growth proteins N-terminal histone-binding
Inh PF02974 Domain 30 573 94.10 24 59.31 Changed Protease inhibitor Inh
Inhibitor_G39P PF11417 Family 7 138 64.20 26 48.23 Changed Loader and inhibitor of phage G40P
Inhibitor_I10 PF12559 Family 5 164 58.90 36 81.04 Changed Serine endopeptidase inhibitors
Inhibitor_I24 PF10465 Family 1 13 131.50 38 92.58 Changed PinA peptidase inhibitor
Inhibitor_I29 PF08246 Domain 59 7047 58.20 31 15.98 Changed Cathepsin propeptide inhibitor domain (I29)
Inhibitor_I34 PF10466 Family 4 5 65.80 45 95.64 Changed Saccharopepsin inhibitor I34
Inhibitor_I36 PF03995 Domain 38 1097 72.90 19 38.60 Changed Peptidase inhibitor family I36
Inhibitor_I42 PF09394 Domain 133 843 90.80 22 54.64 Changed Chagasin family peptidase inhibitor I42
Inhibitor_I48 PF10467 Family 4 57 141.10 31 76.69 Changed Peptidase inhibitor clitocypin
Inhibitor_I53 PF11714 Domain 3 1 77.00 100 100.00 Changed Thrombin inhibitor Madanin
Inhibitor_I66 PF16850 Family 17 276 129.00 21 81.49 Changed Peptidase inhibitor I66
Inhibitor_I67 PF11405 Family 2 4 41.00 81 41.84 Changed Bromelain inhibitor VI
Inhibitor_I68 PF10468 Domain 2 1 82.00 100 100.00 Changed Carboxypeptidase inhibitor I68
Inhibitor_I69 PF13734 Family 84 403 97.70 21 13.56 Changed Spi protease inhibitor
Inhibitor_I71 PF12628 Family 4 29 165.40 55 27.01 Changed Falstatin, cysteine peptidase inhibitor
Inhibitor_I78 PF11720 Domain 3 1315 62.00 28 63.98 Changed Peptidase inhibitor I78 family
Inhibitor_I9 PF05922 Domain 77 10147 81.30 20 12.84 Changed Peptidase inhibitor I9
Inhibitor_Mig-6 PF11555 Family 10 271 64.00 63 8.18 Changed EGFR receptor inhibitor Mig-6
Init_tRNA_PT PF04179 Domain 112 655 111.30 32 22.66 Changed Rit1 DUSP-like domain
Inj_translocase PF16928 Family 4 36 204.60 39 47.28 Changed DNA/protein translocase of phage P22 injectosome
Innate_immun PF12782 Family 1 8 144.00 37 42.32 Changed Invertebrate innate immunity transcript family
Innexin PF00876 Family 221 3827 263.10 23 74.38 Changed Innexin
Ino80_Iec3 PF14612 Family 29 421 165.40 27 57.58 Changed IEC3 subunit of the Ino80 complex, chromatin re-modelling
INO80_Ies4 PF08193 Family 43 351 220.00 33 77.59 Changed INO80 complex subunit Ies4
Inos-1-P_synth PF01658 Family 135 3412 110.30 40 25.98 Changed Myo-inositol-1-phosphate synthase
Inositol_P PF00459 Family 46 22319 259.20 22 92.18 Changed Inositol monophosphatase family
Inovirus_Gp2 PF11726 Family 21 421 165.50 20 67.31 Changed Inovirus Gp2
Inp1 PF12634 Family 38 373 133.30 32 21.83 Changed Inheritance of peroxisomes protein 1
InPase PF18823 Domain 39 88 153.20 32 7.47 New Inorganic Pyrophosphatase
INPP5B_PH PF16776 Domain 17 173 137.50 33 16.20 Changed Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain
Ins134_P3_kin PF05770 Domain 5 1141 182.10 34 51.89 Changed Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain
Ins134_P3_kin_N PF17927 Domain 5 853 80.20 40 21.94 New Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain
Ins145_P3_rec PF08709 Domain 10 1982 194.20 37 6.36 Changed Inositol 1,4,5-trisphosphate/ryanodine receptor
INSC_LBD PF16748 Domain 6 144 45.90 76 8.99 Changed Inscuteable LGN-binding domain
INSIG PF07281 Family 79 733 188.60 37 63.04 Changed Insulin-induced protein (INSIG)
Insulin PF00049 Domain 28 1341 78.70 29 56.96 Changed Insulin/IGF/Relaxin family
Insulin_TMD PF17870 Domain 14 160 47.00 54 3.64 New Insulin receptor trans-membrane segment
Ins_allergen_rp PF06757 Family 85 400 170.10 22 65.85 Changed Insect allergen related repeat, nitrile-specifier detoxification
Ins_beta PF03488 Family 11 221 47.30 29 45.08 Changed Nematode insulin-related peptide beta type
Ins_P5_2-kin PF06090 Family 90 1179 349.70 19 79.70 Changed Inositol-pentakisphosphate 2-kinase
INTAP PF16617 Disordered 11 216 112.30 72 7.79 Changed Intersectin and clathrin adaptor AP2 binding region
Integrase_1 PF12835 Domain 18 430 141.60 24 44.69 Changed Integrase
Integrase_DNA PF02920 Domain 48 430 64.40 49 16.83 Changed DNA binding domain of tn916 integrase
Integrase_H2C2 PF17921 Domain 754 14937 55.80 23 6.78 New Integrase zinc binding domain
Integrase_Zn PF02022 Domain 21 266 37.70 41 7.01 Changed Integrase Zinc binding domain
Integrin_alpha PF00357 Family 24 654 14.90 52 1.48 Changed Integrin alpha cytoplasmic region
Integrin_alpha2 PF08441 Family 37 3001 378.00 19 39.86 Changed Integrin alpha
Integrin_beta PF00362 Domain 137 1784 224.90 47 28.44 Changed Integrin beta chain VWA domain
Integrin_b_cyt PF08725 Domain 67 1226 43.00 51 5.72 Changed Integrin beta cytoplasmic domain
Integrin_B_tail PF07965 Domain 144 1131 84.40 32 9.59 Changed Integrin beta tail domain
Intein_splicing PF14890 Family 17 2101 381.20 14 37.85 Changed Intein splicing domain
Interfer-bind PF09294 Domain 36 1363 100.10 20 28.32 Changed Interferon-alpha/beta receptor, fibronectin type III
Interferon PF00143 Domain 118 792 153.10 34 83.17 Changed Interferon alpha/beta domain
Internalin_N PF12354 Domain 11 14 55.10 29 9.97 Changed Bacterial adhesion/invasion protein N terminal
Intg_mem_TP0381 PF09529 Family 109 919 215.50 21 87.33 Changed Integral membrane protein (intg_mem_TP0381)
Intimin_C PF07979 Domain 14 3 99.30 28 10.96 Changed Intimin C-type lectin domain
Intron_maturas2 PF01348 Family 7 802 128.00 20 22.13 Changed Type II intron maturase
INTS2 PF14750 Family 20 612 633.60 27 78.92 Changed Integrator complex subunit 2
Ints3 PF10189 Family 38 516 202.10 43 23.85 Changed Integrator complex subunit 3
INTS5_C PF14838 Family 14 355 460.20 21 62.48 Changed Integrator complex subunit 5 C-terminus
INTS5_N PF14837 Family 27 249 193.60 33 22.47 Changed Integrator complex subunit 5 N-terminus
INT_SG_DDX_CT_C PF15300 Family 50 472 62.10 47 7.87 Changed INTS6/SAGE1/DDX26B/CT45 C-terminus
Inv-AAD PF18785 Family 42 652 123.70 43 43.94 New Invertebrate-AID/APOBEC-deaminase
Invasin_D3 PF09134 Domain 68 713 99.50 25 18.05 Changed Invasin, domain 3
Invas_SpaK PF03519 Family 7 69 78.00 27 57.04 Changed Invasion protein B family
InvH PF04741 Family 1 3 124.70 50 92.80 Changed InvH outer membrane lipoprotein
Involucrin PF00904 Repeat 36 435 9.80 66 64.16 Changed Involucrin repeat
Involucrin2 PF06994 Family 18 106 38.60 47 49.29 Changed Involucrin
Involucrin_N PF10583 Domain 11 36 68.10 66 16.18 Changed Involucrin of squamous epithelia N-terminus
IN_DBD_C PF00552 Domain 9 80 47.30 35 4.74 Changed Integrase DNA binding domain
Ion_trans PF00520 Family 243 58529 242.00 16 35.69 Changed Ion transport protein
Ion_trans_2 PF07885 Family 103 25187 81.20 20 23.42 Changed Ion channel
Ion_trans_N PF08412 Family 20 568 43.40 61 5.42 Changed Ion transport protein N-terminal
IpaB_EvcA PF03278 Family 2 15 139.50 29 66.07 Changed IpaB/EvcA family
IpaC_SipC PF09599 Family 4 23 280.60 19 81.17 Changed Salmonella-Shigella invasin protein C (IpaC_SipC)
IpgD PF05925 Family 2 52 386.80 21 55.37 Changed Enterobacterial virulence protein IpgD
iPGM_N PF06415 Domain 702 5716 211.90 39 41.73 Changed BPG-independent PGAM N-terminus (iPGM_N)
Ipi1_N PF12333 Family 119 964 101.00 23 16.65 Changed Rix1 complex component involved in 60S ribosome maturation
IPI_T4 PF11634 Family 1 4 73.80 42 78.25 Changed Nuclease inhibitor from bacteriophage T4
IPK PF03770 Family 107 3543 210.10 26 39.52 Changed Inositol polyphosphate kinase
IPP-2 PF04979 Family 110 1408 136.20 26 58.03 Changed Protein phosphatase inhibitor 2 (IPP-2)
IPPT PF01715 Domain 1232 10776 228.50 29 73.38 Changed IPP transferase
IPT PF01745 Domain 7 128 105.10 31 55.35 Changed Isopentenyl transferase
IPTL-CTERM PF18203 Motif 64 170 28.20 40 5.08 New IPTL-CTERM motif
IPU_b_solenoid PF18783 Family 40 101 32.90 51 5.14 New Isopullulanase beta-solenoid repeat
IP_trans PF02121 Family 120 2105 210.30 42 42.94 Changed Phosphatidylinositol transfer protein
IQ PF00612 Motif 247 45178 20.60 33 4.52 Changed IQ calmodulin-binding motif
IQCJ-SCHIP1 PF15157 Family 5 121 105.10 63 69.76 Changed Fusion protein IQCJ-SCHIP1 with IQ-like motif
IQ_SEC7_PH PF16453 Domain 27 834 133.50 54 13.68 Changed PH domain
IR1-M PF12185 Domain 22 237 61.10 50 4.22 Changed Nup358/RanBP2 E3 ligase domain
IreB PF06135 Family 166 1509 78.00 56 89.90 Changed IreB regulatory phosphoprotein
IRF PF00605 Domain 88 1426 102.00 47 25.54 Changed Interferon regulatory factor transcription factor
IRF-2BP1_2 PF11261 Domain 10 370 51.30 75 9.77 Changed Interferon regulatory factor 2-binding protein zinc finger
IRF-3 PF10401 Family 29 1063 167.50 33 39.05 Changed Interferon-regulatory factor 3
IRK PF01007 Domain 38 2805 136.70 44 32.99 Changed Inward rectifier potassium channel transmembrane domain
IRK_C PF17655 Domain 38 3460 160.20 37 41.05 New Inward rectifier potassium channel C-terminal domain
IRK_N PF08466 Family 20 297 45.40 66 10.53 Changed Inward rectifier potassium channel N-terminal
IrmA PF18673 Domain 5 27 101.30 36 66.39 New interleukin receptor mimic protein A
Iron_permease PF04120 Family 44 1315 114.20 29 67.63 Changed Low affinity iron permease
Iron_traffic PF04362 Family 101 1618 87.00 50 95.02 Changed Bacterial Fe(2+) trafficking
Iron_transport PF10634 Family 59 587 145.70 42 72.30 Changed Fe2+ transport protein
IRS PF02174 Domain 26 2128 96.00 27 13.60 Changed PTB domain (IRS-1 type)
ISAV_HA PF06215 Family 2 2 344.00 27 89.47 Changed Infectious salmon anaemia virus haemagglutinin
ISET-FN3_linker PF16625 Disordered 19 107 64.00 53 5.95 Changed Unstructured linking region I-set and fnIII on Brother of CDO
ISG65-75 PF11727 Family 18 107 216.50 17 55.81 Changed Invariant surface glycoprotein
Ish1 PF10281 Repeat 275 2679 36.10 34 34.09 Changed Putative stress-responsive nuclear envelope protein
ISK_Channel PF02060 Family 17 416 100.20 25 71.97 Changed Slow voltage-gated potassium channel
ISN1 PF06437 Family 54 516 367.70 47 88.26 Changed IMP-specific 5'-nucleotidase
Isochorismatase PF00857 Family 61 24896 173.00 20 76.92 Changed Isochorismatase family
Iso_dh PF00180 Domain 20 22412 341.60 31 91.65 Changed Isocitrate/isopropylmalate dehydrogenase
ISP1_C PF18161 Domain 7 52 99.80 41 58.01 New ISP1 C-terminal
ISP3_C PF18045 Domain 9 62 104.40 29 65.96 New ISP3 C-terminal
IspA PF04279 Family 90 2345 181.30 33 91.91 Changed Intracellular septation protein A
IspD PF01128 Family 6 7414 217.70 31 78.23 Changed 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
ISPD_C PF18706 Domain 19 111 144.50 44 38.82 New D-ribitol-5-phosphate cytidylyltransferase C-terminal domain
Ist1 PF03398 Family 128 2465 150.20 34 34.14 Changed Regulator of Vps4 activity in the MVB pathway
IstB_IS21 PF01695 Domain 10 9179 154.80 24 64.23 Changed IstB-like ATP binding protein
IstB_IS21_ATP PF08483 Family 62 751 28.40 40 11.84 Changed IstB-like ATP binding N-terminal
Isy1 PF06246 Family 109 1229 232.70 38 80.58 Changed Isy1-like splicing family
ITAM PF02189 Motif 20 441 20.00 36 13.67 Changed Immunoreceptor tyrosine-based activation motif
ITAM_Cys-rich PF10538 Domain 6 7 24.00 63 2.11 Changed Immunoreceptor tyrosine-based activation motif
Itfg2 PF15907 Family 13 396 220.20 28 55.46 Changed Integrin-alpha FG-GAP repeat-containing protein 2
ITI_HC_C PF06668 Family 63 711 177.20 33 20.45 Changed Inter-alpha-trypsin inhibitor heavy chain C-terminus
IucA_IucC PF04183 Family 231 2893 229.00 26 38.33 Changed IucA / IucC family
IU_nuc_hydro PF01156 Domain 811 8847 302.10 25 89.14 Changed Inosine-uridine preferring nucleoside hydrolase
Ivy PF08816 Family 19 226 109.00 26 67.08 Changed Inhibitor of vertebrate lysozyme (Ivy)
Iwr1 PF08574 Family 103 947 71.90 31 18.69 Changed Transcription factor Iwr1
IZUMO PF15005 Family 35 235 130.20 28 50.60 Changed Izumo sperm-egg fusion, Ig domain-associated
Izumo-Ig PF16706 Domain 14 61 85.20 48 23.25 Changed Izumo-like Immunoglobulin domain
I_LWEQ PF01608 Family 98 1942 139.70 39 11.02 Changed I/LWEQ domain
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