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Browse Pfam families

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ID Accession Type Number of sequences Average length Average %id Average coverage Has 3D Change status Description
Seed Full
1-cysPrx_C PF10417 Domain 46 3774 36.70 33 16.91 Changed C-terminal domain of 1-Cys peroxiredoxin
120_Rick_ant PF12574 Family 1 8 203.80 41 27.41 Changed 120 KDa Rickettsia surface antigen
12TM_1 PF09847 Family 7 33 434.60 16 85.25 Changed Membrane protein of 12 TMs
14-3-3 PF00244 Domain 171 2770 194.50 54 76.05 Changed 14-3-3 protein
17kDa_Anti_2 PF16998 Family 8 177 105.80 24 68.31 Changed 17 kDa outer membrane surface antigen
2-Hacid_dh PF00389 Domain 89 12118 305.90 17 81.99 Changed D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
2-Hacid_dh_C PF02826 Domain 145 14820 171.30 29 47.64 Changed D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
2-oxoacid_dh PF00198 Domain 76 6966 221.70 33 46.16 Changed 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
2-oxogl_dehyd_N PF16078 Family 251 1897 40.00 36 4.05 Changed 2-oxoglutarate dehydrogenase N-terminus
2-ph_phosp PF04029 Family 142 500 218.00 26 90.01 Changed 2-phosphosulpholactate phosphatase
23ISL PF16620 Disordered 19 46 161.90 53 8.85 Changed Unstructured linker between I-set domains 2 and 3 on MYLCK
23S_rRNA_IVP PF05635 Family 414 2098 101.40 23 80.30 Changed 23S rRNA-intervening sequence protein
2CSK_N PF08521 Family 202 916 141.00 20 30.10 Changed Two-component sensor kinase N-terminal
2C_adapt PF08793 Domain 18 23 34.10 32 12.69 Changed 2-cysteine adaptor domain
2Fe-2S_Ferredox PF11591 Family 2 3 33.30 75 26.18 Changed Ferredoxin chloroplastic transit peptide
2Fe-2S_thioredx PF01257 Family 139 3687 129.30 28 48.18 Changed Thioredoxin-like [2Fe-2S] ferredoxin
2H-phosphodiest PF08975 Domain 16 113 109.10 24 39.87 Changed Domain of unknown function (DUF1868)
2HCT PF03390 Family 77 239 392.70 35 92.58 Changed 2-hydroxycarboxylate transporter family
2OG-FeII_Oxy PF03171 Domain 135 11323 103.80 31 30.24 Changed 2OG-Fe(II) oxygenase superfamily
2OG-FeII_Oxy_2 PF13532 Domain 43 3824 193.50 18 52.89 Changed 2OG-Fe(II) oxygenase superfamily
2OG-FeII_Oxy_3 PF13640 Domain 387 5248 104.40 24 28.15 Changed 2OG-Fe(II) oxygenase superfamily
2OG-FeII_Oxy_4 PF13661 Domain 16 499 104.90 41 18.85 Changed 2OG-Fe(II) oxygenase superfamily
2OG-FeII_Oxy_5 PF13759 Domain 37 239 100.30 30 27.85 Changed Putative 2OG-Fe(II) oxygenase
2OG-Fe_Oxy_2 PF10014 Domain 116 295 190.20 28 74.91 Changed 2OG-Fe dioxygenase
2TM PF13239 Family 165 483 78.30 23 48.82 Changed 2TM domain
2_5_RNA_ligase2 PF13563 Family 96 1756 153.60 15 58.35 Changed 2'-5' RNA ligase superfamily
3-alpha PF03475 Domain 98 348 43.30 24 13.63 Changed 3-alpha domain
3-dmu-9_3-mt PF06983 Family 20 1640 123.90 29 82.95 Changed 3-demethylubiquinone-9 3-methyltransferase
3-HAO PF06052 Domain 4 564 142.70 44 73.54 Changed 3-hydroxyanthranilic acid dioxygenase
3-PAP PF12578 Family 25 231 119.90 28 16.93 Changed Myotubularin-associated protein
3A PF00803 Family 8 10 226.60 17 57.69 Changed 3A/RNA2 movement protein family
3Beta_HSD PF01073 Family 9 2360 231.30 23 62.92 Changed 3-beta hydroxysteroid dehydrogenase/isomerase family
3D PF06725 Domain 41 1456 68.90 36 20.39 Changed 3D domain
3H PF02829 Family 220 390 97.10 37 53.21 Changed 3H domain
3HBOH PF10605 Family 17 98 449.90 33 78.49 Changed 3HB-oligomer hydrolase (3HBOH)
3HCDH PF00725 Domain 68 7694 94.40 28 23.29 Changed 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
3HCDH_N PF02737 Domain 60 6696 176.30 31 37.46 Changed 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
40S_S4_C PF16121 Family 83 867 47.10 62 17.15 Changed 40S ribosomal protein S4 C-terminus
40S_SA_C PF16122 Family 23 540 88.50 40 29.61 Changed 40S ribosomal protein SA C-terminus
4F5 PF04419 Family 37 920 36.40 33 43.74 Changed 4F5 protein family
4HBT PF03061 Domain 132 12476 79.00 17 45.92 Changed Thioesterase superfamily
4HBT_2 PF13279 Domain 74 3105 127.40 17 67.01 Changed Thioesterase-like superfamily
4HBT_3 PF13622 Domain 265 2867 254.10 21 82.14 Changed Thioesterase-like superfamily
4HB_MCP_1 PF12729 Family 46 2887 176.30 13 30.44 Changed Four helix bundle sensory module for signal transduction
4_1_CTD PF05902 Domain 16 519 103.60 57 10.63 Changed 4.1 protein C-terminal domain (CTD)
5-FTHF_cyc-lig PF01812 Family 18 3075 179.40 23 83.04 Changed 5-formyltetrahydrofolate cyclo-ligase family
5-nucleotidase PF06189 Family 99 404 256.30 46 75.08 Changed 5'-nucleotidase
53-BP1_Tudor PF09038 Domain 2 90 117.90 64 7.20 Changed Tumour suppressor p53-binding protein-1 Tudor
5HT_transport_N PF03491 Family 10 51 40.30 65 6.72 Changed Serotonin (5-HT) neurotransmitter transporter, N-terminus
5TM-5TMR_LYT PF07694 Domain 71 721 168.10 21 30.41 Changed 5TMR of 5TMR-LYT
5_3_exonuc PF01367 Domain 956 3345 97.20 35 13.23 Changed 5'-3' exonuclease, C-terminal SAM fold
5_3_exonuc_N PF02739 Domain 900 3408 166.10 34 22.98 Changed 5'-3' exonuclease, N-terminal resolvase-like domain
5_nucleotid PF05761 Family 115 1091 367.00 29 80.74 Changed 5' nucleotidase family
5_nucleotid_C PF02872 Domain 62 3573 166.30 21 27.62 Changed 5'-nucleotidase, C-terminal domain
60KD_IMP PF02096 Family 558 4376 201.70 24 48.73 Changed 60Kd inner membrane protein
6PF2K PF01591 Domain 11 1952 192.60 35 39.66 Changed 6-phosphofructo-2-kinase
6PGD PF00393 Domain 408 2845 230.10 40 55.97 Changed 6-phosphogluconate dehydrogenase, C-terminal domain
7kD_coat PF02495 Family 61 6 58.80 23 35.12 Changed 7kD viral coat protein
7kD_DNA_binding PF02294 Domain 3 9 58.10 88 92.08 Changed 7kD DNA-binding domain
7TM-7TMR_HD PF07698 Domain 71 596 192.10 19 27.05 Changed 7TM receptor with intracellular HD hydrolase
7TMR-DISMED2 PF07696 Domain 243 718 133.10 17 18.14 Changed 7TMR-DISM extracellular 2
7TMR-DISM_7TM PF07695 Domain 176 1111 202.80 15 28.23 Changed 7TM diverse intracellular signalling
7TMR-HDED PF07697 Domain 220 569 226.50 17 31.48 Changed 7TM-HD extracellular
7tm_1 PF00001 Family 64 31273 254.20 18 68.24 Changed 7 transmembrane receptor (rhodopsin family)
7tm_2 PF00002 Family 29 5681 225.20 22 27.91 Changed 7 transmembrane receptor (Secretin family)
7tm_3 PF00003 Family 810 4578 229.40 26 30.20 Changed 7 transmembrane sweet-taste receptor of 3 GCPR
7tm_4 PF13853 Family 5 28177 264.60 37 87.90 Changed Olfactory receptor
7tm_6 PF02949 Family 36 2993 246.10 14 74.57 Changed 7tm Odorant receptor
7tm_7 PF08395 Family 76 1558 317.50 12 87.59 Changed 7tm Chemosensory receptor
7TM_GPCR_Sra PF02117 Family 10 164 263.00 19 91.52 Changed Serpentine type 7TM GPCR chemoreceptor Sra
7TM_GPCR_Srab PF10292 Family 17 391 228.70 16 84.98 Changed Serpentine type 7TM GPCR receptor class ab chemoreceptor
7TM_GPCR_Srb PF02175 Family 3 75 186.30 31 65.71 Changed Serpentine type 7TM GPCR chemoreceptor Srb
7TM_GPCR_Srbc PF10316 Family 60 352 209.20 20 84.72 Changed Serpentine type 7TM GPCR chemoreceptor Srbc
7TM_GPCR_Srd PF10317 Family 56 623 194.40 16 80.18 Changed Serpentine type 7TM GPCR chemoreceptor Srd
7TM_GPCR_Srh PF10318 Family 177 1121 239.10 20 83.66 Changed Serpentine type 7TM GPCR chemoreceptor Srh
7TM_GPCR_Sri PF10327 Family 51 370 219.00 21 81.75 Changed Serpentine type 7TM GPCR chemoreceptor Sri
7TM_GPCR_Srj PF10319 Family 35 219 219.20 29 85.36 Changed Serpentine type 7TM GPCR chemoreceptor Srj
7TM_GPCR_Srsx PF10320 Family 23 540 191.30 14 72.68 Changed Serpentine type 7TM GPCR chemoreceptor Srsx
7TM_GPCR_Srt PF10321 Family 38 534 224.10 22 87.40 Changed Serpentine type 7TM GPCR chemoreceptor Srt
7TM_GPCR_Sru PF10322 Family 110 310 223.50 25 90.43 Changed Serpentine type 7TM GPCR chemoreceptor Sru
7TM_GPCR_Srv PF10323 Family 25 520 216.00 14 83.88 Changed Serpentine type 7TM GPCR chemoreceptor Srv
7TM_GPCR_Srw PF10324 Family 87 1465 231.70 17 73.05 Changed Serpentine type 7TM GPCR chemoreceptor Srw
7TM_GPCR_Srx PF10328 Family 76 1022 200.70 15 77.22 Changed Serpentine type 7TM GPCR chemoreceptor Srx
7TM_GPCR_Srz PF10325 Family 58 370 209.10 21 75.90 Changed Serpentine type 7TM GPCR chemoreceptor Srz
7TM_GPCR_Str PF10326 Family 168 1630 220.70 19 81.38 Changed Serpentine type 7TM GPCR chemoreceptor Str
7TM_transglut PF14402 Family 50 258 269.50 33 63.80 Changed 7 transmembrane helices usually fused to an inactive transglutaminase
8TM_micro PF17028 Family 7 10 258.40 24 92.98 Changed 8TM Microsporidial transmembrane domain
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