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Browse Pfam families

New Top twenty Numbers A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
ID Accession Type Number of sequences Average length Average %id Average coverage Has 3D Change status Description
Seed Full
1-cysPrx_C PF10417 Domain 46 9746 36.60 33 17.16 Changed C-terminal domain of 1-Cys peroxiredoxin
120_Rick_ant PF12574 Family 4 16 203.20 32 30.59 Changed 120 KDa Rickettsia surface antigen
12TM_1 PF09847 Family 7 63 444.00 17 87.56 Changed Membrane protein of 12 TMs
14-3-3 PF00244 Domain 168 4872 197.00 55 77.23 Changed 14-3-3 protein
17kDa_Anti_2 PF16998 Family 7 657 107.40 24 70.30 Changed 17 kDa outer membrane surface antigen
2-Hacid_dh PF00389 Domain 88 35295 306.70 17 83.45 Changed D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
2-Hacid_dh_C PF02826 Domain 144 42999 172.80 29 48.49 Changed D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
2-oxoacid_dh PF00198 Domain 75 21401 223.60 33 45.53 Changed 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
2-oxogl_dehyd_N PF16078 Family 242 5727 40.00 35 4.01 Changed 2-oxoglutarate dehydrogenase N-terminus
2-ph_phosp PF04029 Family 141 1600 216.30 26 89.83 Changed 2-phosphosulpholactate phosphatase
23ISL PF16620 Disordered 18 125 162.80 47 8.84 Changed Unstructured linker between I-set domains 2 and 3 on MYLCK
23S_rRNA_IVP PF05635 Family 410 6827 102.20 24 82.70 Changed 23S rRNA-intervening sequence protein
2CSK_N PF08521 Family 187 3588 141.40 19 30.17 Changed Two-component sensor kinase N-terminal
2C_adapt PF08793 Domain 18 93 34.70 43 18.35 Changed 2-cysteine adaptor domain
2Fe-2S_Ferredox PF11591 Family 2 5 33.20 74 26.14 Changed Ferredoxin chloroplastic transit peptide
2Fe-2S_thioredx PF01257 Family 138 10827 131.50 28 48.15 Changed Thioredoxin-like [2Fe-2S] ferredoxin
2H-phosphodiest PF08975 Domain 15 285 110.20 24 42.74 Changed Domain of unknown function (DUF1868)
2HCT PF03390 Family 77 652 393.10 36 92.58 Changed 2-hydroxycarboxylate transporter family
2OG-FeII_Oxy PF03171 Domain 135 22347 104.80 31 30.41 Changed 2OG-Fe(II) oxygenase superfamily
2OG-FeII_Oxy_2 PF13532 Domain 39 9220 191.50 19 56.00 Changed 2OG-Fe(II) oxygenase superfamily
2OG-FeII_Oxy_3 PF13640 Domain 369 12127 102.30 23 29.69 Changed 2OG-Fe(II) oxygenase superfamily
2OG-FeII_Oxy_4 PF13661 Domain 16 1176 103.50 37 19.57 Changed 2OG-Fe(II) oxygenase superfamily
2OG-FeII_Oxy_5 PF13759 Domain 35 1153 99.60 30 34.39 Changed Putative 2OG-Fe(II) oxygenase
2OG-Fe_Oxy_2 PF10014 Domain 112 931 190.90 30 76.39 Changed 2OG-Fe dioxygenase
2TM PF13239 Family 164 2027 79.60 26 48.26 Changed 2TM domain
2_5_RNA_ligase2 PF13563 Family 95 6161 152.80 16 66.65 Changed 2'-5' RNA ligase superfamily
3-alpha PF03475 Domain 95 1103 43.20 24 13.95 Changed 3-alpha domain
3-dmu-9_3-mt PF06983 Family 20 6659 124.50 28 83.58 Changed 3-demethylubiquinone-9 3-methyltransferase
3-HAO PF06052 Domain 4 1536 145.80 43 76.73 Changed 3-hydroxyanthranilic acid dioxygenase
3-PAP PF12578 Family 25 457 119.30 28 17.00 Changed Myotubularin-associated protein
30K_MP_core PF17644 Domain 1 3 140.00 34 29.09 New Core domain of 30K viral movement proteins
30K_MP_C_Ter PF11330 Family 1 2 247.50 36 49.95 Changed C-Terminal of 30K viral movement proteins
3A PF00803 Family 8 35 230.70 19 73.04 Changed 3A/RNA2 movement protein family
3Beta_HSD PF01073 Family 8 4705 234.00 24 63.98 Changed 3-beta hydroxysteroid dehydrogenase/isomerase family
3D PF06725 Domain 41 4638 69.10 37 20.43 Changed 3D domain
3H PF02829 Family 216 989 97.20 38 54.00 Changed 3H domain
3HBOH PF10605 Family 17 345 475.60 34 80.55 Changed 3HB-oligomer hydrolase (3HBOH)
3HCDH PF00725 Domain 68 25719 94.30 28 23.19 Changed 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
3HCDH_N PF02737 Domain 60 22104 177.10 32 37.22 Changed 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
3HCDH_RFF PF18321 Domain 29 469 67.20 40 13.29 New 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain
40S_S4_C PF16121 Family 76 1545 46.60 62 17.21 Changed 40S ribosomal protein S4 C-terminus
40S_SA_C PF16122 Family 23 915 88.50 36 29.88 Changed 40S ribosomal protein SA C-terminus
4F5 PF04419 Family 37 1716 36.60 32 40.28 Changed 4F5 protein family
4HB PF17947 Domain 94 415 77.20 41 7.42 New Four helical bundle domain
4HBT PF03061 Domain 132 40361 79.30 17 48.07 Changed Thioesterase superfamily
4HBT_2 PF13279 Domain 72 10514 126.30 17 70.15 Changed Thioesterase-like superfamily
4HBT_3 PF13622 Domain 262 8993 250.00 22 83.85 Changed Thioesterase-like superfamily
4HB_MCP_1 PF12729 Family 46 9137 176.50 14 30.96 Changed Four helix bundle sensory module for signal transduction
4HFCP_synth PF04476 Family 61 396 217.90 36 85.12 Changed 4-HFC-P synthase
4HPAD_g_N PF18671 Domain 7 28 30.90 44 35.53 New 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal
4PPT_N PF17837 Domain 47 1567 67.90 38 29.04 New 4'-phosphopantetheinyl transferase N-terminal domain
4_1_CTD PF05902 Domain 15 1329 102.70 59 10.49 Changed 4.1 protein C-terminal domain (CTD)
5-FTHF_cyc-lig PF01812 Family 18 8740 178.40 24 84.55 Changed 5-formyltetrahydrofolate cyclo-ligase family
5-nucleotidase PF06189 Family 96 1212 256.60 45 78.90 Changed 5'-nucleotidase
53-BP1_Tudor PF09038 Domain 2 196 118.60 60 7.31 Changed Tumour suppressor p53-binding protein-1 Tudor
5HT_transport_N PF03491 Family 10 106 37.50 58 6.04 Changed Serotonin (5-HT) neurotransmitter transporter, N-terminus
5TM-5TMR_LYT PF07694 Domain 71 2198 167.80 20 31.45 Changed 5TMR of 5TMR-LYT
5_3_exonuc PF01367 Domain 937 10023 97.10 35 13.10 Changed 5'-3' exonuclease, C-terminal SAM fold
5_3_exonuc_N PF02739 Domain 884 10260 167.10 35 22.90 Changed 5'-3' exonuclease, N-terminal resolvase-like domain
5_nucleotid PF05761 Family 106 2335 349.70 30 77.87 Changed 5' nucleotidase family
5_nucleotid_C PF02872 Domain 62 10726 167.10 21 27.49 Changed 5'-nucleotidase, C-terminal domain
60KD_IMP PF02096 Family 546 11364 201.70 27 47.16 Changed 60Kd inner membrane protein
6PF2K PF01591 Domain 11 3821 192.40 36 40.03 Changed 6-phosphofructo-2-kinase
6PGD PF00393 Domain 396 8460 218.00 38 54.90 Changed 6-phosphogluconate dehydrogenase, C-terminal domain
7kD_DNA_binding PF02294 Domain 3 18 56.30 85 93.20 Changed 7kD DNA-binding domain
7TM-7TMR_HD PF07698 Domain 71 1745 192.50 19 27.26 Changed 7TM receptor with intracellular HD hydrolase
7TMR-DISMED2 PF07696 Domain 237 2654 132.40 17 18.19 Changed 7TMR-DISM extracellular 2
7TMR-DISM_7TM PF07695 Domain 176 4115 202.20 15 28.44 Changed 7TM diverse intracellular signalling
7TMR-HDED PF07697 Domain 218 1650 227.80 17 31.72 Changed 7TM-HD extracellular
7tm_1 PF00001 Family 64 56771 255.40 18 67.02 Changed 7 transmembrane receptor (rhodopsin family)
7tm_2 PF00002 Family 28 11228 225.00 23 27.34 Changed 7 transmembrane receptor (Secretin family)
7tm_3 PF00003 Family 775 8807 226.70 24 29.78 Changed 7 transmembrane sweet-taste receptor of 3 GCPR
7tm_4 PF13853 Family 5 37861 259.70 36 87.63 Changed Olfactory receptor
7tm_6 PF02949 Family 36 6746 251.50 13 74.84 Changed 7tm Odorant receptor
7tm_7 PF08395 Family 76 3591 308.00 11 83.88 Changed 7tm Chemosensory receptor
7TM_GPCR_Sra PF02117 Family 10 297 242.40 18 90.87 Changed Serpentine type 7TM GPCR chemoreceptor Sra
7TM_GPCR_Srab PF10292 Family 17 950 226.10 14 81.28 Changed Serpentine type 7TM GPCR receptor class ab chemoreceptor
7TM_GPCR_Srb PF02175 Family 3 140 168.60 30 63.45 Changed Serpentine type 7TM GPCR chemoreceptor Srb
7TM_GPCR_Srbc PF10316 Family 59 574 204.30 19 82.03 Changed Serpentine type 7TM GPCR chemoreceptor Srbc
7TM_GPCR_Srd PF10317 Family 55 1191 191.40 15 78.02 Changed Serpentine type 7TM GPCR chemoreceptor Srd
7TM_GPCR_Srh PF10318 Family 174 2346 219.30 17 81.44 Changed Serpentine type 7TM GPCR chemoreceptor Srh
7TM_GPCR_Sri PF10327 Family 51 599 199.90 19 76.97 Changed Serpentine type 7TM GPCR chemoreceptor Sri
7TM_GPCR_Srj PF10319 Family 35 393 208.20 30 83.43 Changed Serpentine type 7TM GPCR chemoreceptor Srj
7TM_GPCR_Srsx PF10320 Family 23 1522 183.00 13 71.46 Changed Serpentine type 7TM GPCR chemoreceptor Srsx
7TM_GPCR_Srt PF10321 Family 37 1445 208.80 20 83.74 Changed Serpentine type 7TM GPCR chemoreceptor Srt
7TM_GPCR_Sru PF10322 Family 109 555 208.10 24 88.54 Changed Serpentine type 7TM GPCR chemoreceptor Sru
7TM_GPCR_Srv PF10323 Family 25 937 201.80 14 80.04 Changed Serpentine type 7TM GPCR chemoreceptor Srv
7TM_GPCR_Srw PF10324 Family 85 3057 227.00 16 69.18 Changed Serpentine type 7TM GPCR chemoreceptor Srw
7TM_GPCR_Srx PF10328 Family 86 2668 183.20 13 73.02 Changed Serpentine type 7TM GPCR chemoreceptor Srx
7TM_GPCR_Srz PF10325 Family 55 582 188.10 20 74.00 Changed Serpentine type 7TM GPCR chemoreceptor Srz
7TM_GPCR_Str PF10326 Family 162 3208 206.20 18 78.28 Changed Serpentine type 7TM GPCR chemoreceptor Str
7TM_transglut PF14402 Family 50 673 234.50 38 51.97 Changed 7 transmembrane helices usually fused to an inactive transglutaminase
8TM_micro PF17028 Family 7 18 242.60 21 92.66 Changed 8TM Microsporidial transmembrane domain
New Top twenty Numbers A B C D E F G H I J K L M N O P Q R S T U V W X Y Z