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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A0A0B4K765_DROME (A0A0B4K765)

Summary

This is the summary of UniProt entry A0A0B4K765_DROME (A0A0B4K765).

Description: Sin3A, isoform G {ECO:0000313|EMBL:AFH08036.1}
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
Length: 2066 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 19
disorder n/a 21 47
low_complexity n/a 22 59
disorder n/a 49 50
disorder n/a 52 53
disorder n/a 70 76
disorder n/a 84 96
low_complexity n/a 94 105
disorder n/a 99 113
low_complexity n/a 110 156
disorder n/a 165 166
disorder n/a 170 210
low_complexity n/a 190 201
disorder n/a 226 270
Pfam PAH 291 335
low_complexity n/a 351 361
disorder n/a 354 374
low_complexity n/a 358 369
low_complexity n/a 389 418
disorder n/a 430 500
low_complexity n/a 499 515
disorder n/a 507 563
low_complexity n/a 530 541
disorder n/a 567 571
Pfam PAH 588 645
disorder n/a 604 615
disorder n/a 617 618
disorder n/a 642 644
disorder n/a 649 702
low_complexity n/a 684 694
disorder n/a 724 745
disorder n/a 752 787
low_complexity n/a 769 785
disorder n/a 791 848
disorder n/a 850 893
disorder n/a 902 905
Pfam PAH 936 980
disorder n/a 990 1018
Pfam Sin3_corepress 1034 1134
disorder n/a 1197 1199
disorder n/a 1248 1252
disorder n/a 1254 1259
disorder n/a 1283 1292
low_complexity n/a 1289 1301
disorder n/a 1295 1296
disorder n/a 1312 1313
disorder n/a 1315 1316
disorder n/a 1320 1473
low_complexity n/a 1385 1408
low_complexity n/a 1407 1427
low_complexity n/a 1445 1456
disorder n/a 1477 1491
Pfam Sin3a_C 1502 1790
low_complexity n/a 1527 1540
disorder n/a 1546 1547
disorder n/a 1715 1754
disorder n/a 1778 1780
disorder n/a 1782 1842
low_complexity n/a 1811 1835
disorder n/a 1941 1957
disorder n/a 1975 2009
disorder n/a 2012 2013
disorder n/a 2022 2066
low_complexity n/a 2030 2042
low_complexity n/a 2047 2057

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0A0B4K765. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MMKRTRVDEV QFGTRPVPQT SGGVGVGVVG VTGGGPTSGG GGTATVGVNT
50
51
TGVTIGTVVP SAHNATISGI GSIHHRILTP QHGGAQTIAY LPSTTPTATN
100
101
LKTTTSIVDS TTAGGPVGAG AQVAVGVGSA AGGGGVVVST GSTGTQTLQY
150
151
TTSYSVASIQ AGGTLKANTA DGANTVQIHV TGGGAANNPA SAQTVSSSSQ
200
201
TGTIRQRTIS GTQTVATAVG NLATISQQQP VQQSPLGKAQ TPPSSVVANS
250
251
IPVGGTTPPQ GQSGNATPRL KVEDALSYLD QVKYQYADQP QIYNNFLDIM
300
301
KEFKSHCIDT PGVIERVSTL FKGHTELIYG FNMFLPPGYK IEIHSDALGC
350
351
SVPVVSMPSP PGAPTSTGTV HMLTGNSSMS GAGHIAIKTT NAATLTPAAG
400
401
AGAAAAAAAV AQIQSAGAVN LMTHGGASLT QTTIHALQQA TPPQSQSPGG
450
451
GHVHVSVTNS TAANAVVPGQ PGISVSAHNV PQNYSRDRER ATITPTGQVA
500
501
GAAANVNASA SIVVGGPPTP NSLSELSPHG GAGGGPGAGA AQHNLHHIQQ
550
551
AHQSILLGET GQQNQPVEFN HAITYVNKIK NRFQNQPAKY KKFLEILHDY
600
601
QREQKVMKEG SLNQGKMLTE QEVYTQVAKL FGQDEDLLRE FGQFLPDATN
650
651
HQSGQYMSKS ASVHNDHGKR PTATLSGGAH ITMSSASPAP SGSPLHLGAT
700
701
TLPQIDKSAH AAAIGNLSAV NTSVSIKTYN NNQQQQNHVI GSGLNATRND
750
751
ILFEKDYHAG LQQQAHQRGA GVGGHHHLAG TAAGANIGRP GVGASVMVSY
800
801
DKEHRNNHHV QKYVGHAPNQ NLTHGHNAKK SPSYGIPSVI GSMPHISDNS
850
851
LDRSSPGISY ATPPLPSGPH GQHNSGSATR RPGDDSLVGH YASGAPPAKR
900
901
PKPYCRDVSF SEASSKCTIS DAAFFDKVRK ALRSPEVYDN FLRCLTLFNQ
950
951
EIVSKTELLG LVSPFLMKFP DLLRWFTDFL GPPSGQPAGG LIDGMPLAAT
1000
1001
QRQGGGSSNS SHDRGTSHQS AAEYVQDVDL SSCKRLGASY CALPQSTVPK
1050
1051
KCSGRTALCR EVLNDKWVSF PTWASEDSTF VTSRKTQFEE TIYRNIHRTE
1100
1101
DERFELDLVI EVNSATIRVL ENLQKKMSRM STEELSKFHL DDHLGGTSQT
1150
1151
IHQRAIHRIY GDKSGEIITG MKKNPFVAVP IVLKRLKVKE EEWREAQKTF
1200
1201
NKQWREQNEK YYLKSLDHQA INFKPNDMKA LRSKSLFNEI ETLYDERHDQ
1250
1251
EDDAMEPFGP HLVLPYKDKT ILDDAANLLI HHVKRQTGIQ KQEKQKIKQI
1300
1301
IRQFVPDLFF APRQPLSDDE RDDAFPFLVD DNTKMDVDSP LGRTESSTRN
1350
1351
AKSTPSESAS PARSNASTSS VTPAGIKKET DDSKATTGSF APASSATASS
1400
1401
ATPVDDATPS TSSAAAAASA ASSSTVSGTE GKPKDDPLSS HKEEGAGSTS
1450
1451
SGVATSPRQA QDTAGAGVDV EIKLEHPADF SNPKLLPPHA HGQREDESYT
1500
1501
LFFANNNWYL FLRLHAILCD RLHVMYERAR LLAIEEERCR VNRRESTATA
1550
1551
LRLKPKPEIQ VEDYYPTFLD MLKNVLDGNM DSNTFEDTMR EMFGIYAYIS
1600
1601
FTLDKVVSNA VRQLQYCVTE RAALDCVELF ATEQRRGCTG GFCRDAHKTF
1650
1651
DREMSYQRKA ESILNEENCF KVYIYKIDCR VTIELLDSEP EEVDKPAALK
1700
1701
AQKFSKYVER LANPALGGGG NTGRSDSALG NDSVVDGSDI KTEADEDTAE
1750
1751
LRYREGGIGG AGKARFLVRN KRRSKLLEEQ VRQLFEHRRN RIEQHGTAAS
1800
1801
LEPISVDSAI SSNSTTGGGG SGTNNNNNNN NNNNSWGGKR LERLGAPQVG
1850
1851
LAEQYAFNDR DEISTNISNG RCFVTSKNLK LLKYDAVRRA KKSHCRVTQA
1900
1901
KYAHFQTYVN KWLQQHVSEQ QQQNCVDWLL GKTADQINAS GWGSASKTKT
1950
1951
VQQKDTSKTP YRIYNRYRVV QSAVSGGLMS ATAPTPDGSV PAVNSAPSGS
2000
2001
VSTVNNVQGS AAVSSTSHSM CNSSILSADS TTNTNASAQQ QQHCNSAAAA
2050
2051
TTPNAEALQQ VRPMES                                     
2066
 

Show the unformatted sequence.

Checksums:
CRC64:738C7F4FD5F4BA78
MD5:f9839fdb7e02251b9292bcf287a07436

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;