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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A0A0R4IEP9_DANRE (A0A0R4IEP9)

Summary

This is the summary of UniProt entry A0A0R4IEP9_DANRE (A0A0R4IEP9).

Description: TRAF2 and NCK-interacting kinase a {ECO:0000313|Ensembl:ENSDARP00000133707}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 1332 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Pkinase 25 289
low_complexity n/a 61 65
disorder n/a 281 288
disorder n/a 300 348
low_complexity n/a 318 338
disorder n/a 354 357
disorder n/a 366 392
low_complexity n/a 369 380
coiled_coil n/a 387 502
low_complexity n/a 389 423
disorder n/a 397 432
low_complexity n/a 417 446
low_complexity n/a 437 471
disorder n/a 438 442
low_complexity n/a 477 494
disorder n/a 479 485
disorder n/a 490 940
low_complexity n/a 500 508
low_complexity n/a 600 615
low_complexity n/a 696 710
low_complexity n/a 734 756
low_complexity n/a 823 836
disorder n/a 943 944
disorder n/a 949 974
disorder n/a 996 1010
Pfam CNH 1028 1302

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0A0R4IEP9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASDSPARSL DEIDLSTLRD PAGIFELVEL VGNGTYGQVY KGRHVKTGQL
50
51
AAIKCMDVTG EEEEEIKAEI NMLKKYSHHR NIATYYGAFI KKNPPGVDDQ
100
101
LWLVMEFCGA GSVTDLIKNT KGNSLKEDWT AYISREILRG LTHLHQHKVI
150
151
HRDIKGQNVL LTENAEVKLV DFGVSAQLDR TVSRRNTFIG TPYWMAPEVI
200
201
ACDENPDATY DYKSDLWSLG ITALEMAEGA PPLCELHPMR ALFLIPRNAP
250
251
PRLKSKKWTK RFHSFIESCL VKNHNMRPGT DQLLKHPFIR DMANERTIRI
300
301
QLKDHIDRTR KKRGERDETE YEYSGSEEEE EAMLEIGEPS SIINIPGEST
350
351
LRRDFLRLQV ANKERSDALR RQQLEQQQNE GHKHQLLAER QKRIEEQKEQ
400
401
RRRLEEQQRR EREARKQQEQ RHRYEELRRE EERRQAEREQ EYIRRQLEEE
450
451
QRQLEILQQQ LLQEQALLLE YKRKQVEEQR QADRLQRQLQ QERAYLVSLQ
500
501
QQQQQQQQDS RPEEKKQLYH YKDAVNPSDK PAWAKKVEER SKLNRQSSPA
550
551
LQHKVANRIS DPSLPPRSES FSSGGMQPAR TPPMHRPVEP QMAHLVPVRS
600
601
HSSSMSVSQS LHDQSAKGVS AFQESLVSNR PEMPRQNSDP TSEMPPPAPR
650
651
MASHEEKPDR SSPWLREDAV PPKLSGTTQV PQRTTSISPA LARKNSPGNG
700
701
ESSGGGRSAS QLIRTSNPDL RRTELSLDVA LQRTSSNSSS SSSTPSSQGG
750
751
SQPGSSERNQ PRGSGKSEGS PVALQETSKP IQEEGRELSK PSRPADLTAL
800
801
AKELRELRID EVSRPPLKLT DYSSSSEDSD SSEDEDGTVG HDGTVSVSDI
850
851
PRIMPSVQGN NESFTSSHDD SLTDSYNDES KDGTLRMREN NERQRLGHGE
900
901
SNGFAGHGNL PDLLQQSHSP SGTPTGLNSQ DLDSMDEFGL GGGSKASFTP
950
951
FVDPRVYQTS PTDDNDESSA AAMFANELLR QEQAKLNEAR KISVVNVNPT
1000
1001
NIRPHSDTPE IRKYKKRFNS EILCAALWGV NLLVGTENGL MLLDRSGQGK
1050
1051
VYNLITRRRF QQMDVLEGLN VLVTISGKKN KLRVYYLSWL RNRILHNDPE
1100
1101
VEKKQGWITV GELEGCIHYK VVKYERIKFL VIALKNSVEI YAWAPKPYHK
1150
1151
FMAFKSFTEL QHRPQLVDLT VEEGQRLKVI YGSSVGFHVI DVDSGSPYDI
1200
1201
YIPSHIQSTV TPHAIVVLPK TDGMEMLLCY EDEGVYVNTY GRITKDVVLQ
1250
1251
WGEMPTSVAY IHSNQIMGWG EKAIEIRSVE TGHLDGVFMH KRAQRLKFLC
1300
1301
ERNDKVFFAS VRSGGSSQVF FMTLNRNSLM NW                   
1332
 

Show the unformatted sequence.

Checksums:
CRC64:F3AF8154C1634EC5
MD5:14a7c1ed2858c69deccd25fe5ca9d012

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;