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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A0A0R4J8E6_DANRE (A0A0R4J8E6)

Summary

This is the summary of UniProt entry A0A0R4J8E6_DANRE (A0A0R4J8E6).

Description: Pre-mRNA-processing factor 8 {ECO:0000313|Ensembl:ENSDARP00000121091}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 2342 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 5 6
disorder n/a 8 32
low_complexity n/a 11 29
disorder n/a 39 40
disorder n/a 43 46
disorder n/a 63 64
Pfam PRO8NT 65 216
disorder n/a 71 77
disorder n/a 79 82
low_complexity n/a 157 173
low_complexity n/a 173 182
disorder n/a 370 371
disorder n/a 373 375
low_complexity n/a 376 389
disorder n/a 377 378
Pfam PROCN 402 808
Pfam RRM_4 993 1084
low_complexity n/a 997 1006
Pfam U5_2-snRNA_bdg 1217 1350
Pfam U6-snRNA_bdg 1449 1607
Pfam PRP8_domainIV 1767 1996
disorder n/a 2030 2042
disorder n/a 2044 2062
disorder n/a 2065 2068
Pfam JAB 2106 2212
disorder n/a 2169 2170
disorder n/a 2187 2207
Pfam PROCT 2219 2340
disorder n/a 2243 2251
disorder n/a 2253 2258

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0A0R4J8E6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAAPFPYRGL PGPMPPGVPP PPPAVAPVPD YMTEEKLQEK ARKWQQLQAK
50
51
RYSEKRKFGF VDAQKEDMPP EHVRKIIRDH GDMTNRKFRH DKRVYLGALK
100
101
YMPHAVLKLL ENMPMPWEQI RDVPVLYHIT GAISFVNEIP WVIEPVYISQ
150
151
WGTMWIMMRR EKRDRRHFKR MRFPPFDDEE PPLDYADNIL DVEPLEAIQM
200
201
ELDPDEDSSV TDWLYEHQPL KDTTKYVNGT TYRRWQFTLP MMSTLYRLAN
250
251
QLLTDLVDDN YFYLFDLKAF FTSKALNMAI PGGPKFEPLV RDINLQDEDW
300
301
NEFNDINKII IRQPIRTEYK IAFPYLYNNL PHHVHLTWYH TPNVVFIKTE
350
351
DPDLPAFYFD PLINPISHRH SVKSQEPLPD DDEEFELPEY VEPFLKETPL
400
401
YTDNTANGIA LLWAPRPFNL RSGRTRRAID VPLVKNWYRE HCPAGQPVKV
450
451
RVSYQKLLKY YVLNALKHRP PKAQKKRYLF RSFKATKFFQ STKLDWVEVG
500
501
LQVCRQGYNM LNLLIHRKNL NYLHLDYNFN LKPVKTLTTK ERKKSRFGNA
550
551
FHLCREVLRL SKLVVDSHVQ YRLGNVDAFQ LADGLQYIFA HVGQLTGMYR
600
601
YKYKLMRQIR MCKDLKHLIY YRFNTGPVGK GPGCGFWAPG WRVWLFFMRG
650
651
ITPLLERWLG NLLARQFEGR HSKGVAKTVT KQRVESHFDL ELRAAVMHDI
700
701
LDMMPEGIKQ NKARTILQHL SESWRCWKAN IPWKVPGLPT PIENMILRYV
750
751
KAKADWWTNT AHYNRERIRR GATVDKTVCK KNLGRLTRLY LKAEQERQHN
800
801
YLKDGPYITA EEAVAIYTTT VHWLESRRFS PIPFPPLSYK HDTKLLILAL
850
851
ERLKEAYSVK SRLNQSQREE LGLIEQAYDN PHEALSRIKR HLLTQRAFKE
900
901
VGIEFMDLYS HLVPVYDVEP LEKITDAYLD QYLWYEADKR RLFPPWIKPA
950
951
DTEPPPLLVY KWCQGINNLQ DVWETAEGEC NVMLESRYEK MYEKIDLTLL
1000
1001
NRLLRLIVDH NIADYMTAKN NVVINYKDMN HTNSYGIIRG LQFASFIVQY
1050
1051
YGLVMDLLVL GLHRASEMAG PPQMPNDFLS FQDTATESAH PIRLYCRYID
1100
1101
RIHIFFRFSA DEARDLIQRY LTEHPDPNNE NIVGYNNKKC WPRDARMRLM
1150
1151
KHDVNLGRAV FWDIKNRLPR SVTTIQWENS FVSVYSKDNP NLLFNMCGFE
1200
1201
CRILPKCRTS YEEFTHKDGV WNLQNEVTKE RTAQCFLRVD DESMQRFHNR
1250
1251
VRQILMASGS TTFTKIVNKW NTALIGLMTY FREAVVNTQE LLDLLVKCEN
1300
1301
KIQTRIKIGL NSKMPSRFPP VVFYTPKELG GLGMLSMGHV LIPQSDLRWS
1350
1351
KQTDVGITHF RSGMSHEEDQ LIPNLYRYIQ PWESEFIDSQ RVWAEYALKR
1400
1401
QEAIAQNRRL TLEDLEDSWD RGIPRINTLF QKDRHTLAYD KGWRVRTDFK
1450
1451
QYQVLKQNPF WWTHQRHDGK LWNLNNYRTD MIQALGGVEG ILEHTLFKGT
1500
1501
YFPTWEGLFW EKASGFEESM KWKKLTNAQR SGLNQIPNRR FTLWWSPTIN
1550
1551
RANVYVGFQV QLDLTGIFMH GKIPTLKISL IQIFRAHLWQ KIHESIVMDL
1600
1601
CQVFDQELDA LEIETVQKET IHPRKSYKMN SSCADILLFA SYKWNVSRPS
1650
1651
LLADSKDVMD STTTQKFWID IQLRWGDYDS HDIERYARAK FLDYTTDNMS
1700
1701
IYPSPTGVLI AIDLAYNLHS AYGNWFPGAK PLIQQAMAKI MKANPALYVL
1750
1751
RERIRKGLQL YSSEPTEPYL SSQNYGELFS NQIIWFVDDT NVYRVTIHKT
1800
1801
FEGNLTTKPI NGAIFIFNPR TGQLFLKIIH TSVWAGQKRL GQLAKWKTAE
1850
1851
EVAALIRSLP VEEQPKQIIV TRKGMLDPLE VHLLDFPNIV IKGSELQLPF
1900
1901
QACLKVEKFG DLILKATEPQ MVLFNLYDDW LKTISSYTAF SRLILILRAL
1950
1951
HVNNDRAKVI LKPDKTTITE PHHIWPTLTD EEWIKVEVQL KDLILADYGK
2000
2001
KNNVNVASLT QSEIRDIILG MEISAPSQQR QQIAEIEKQT KEQSQLTATQ
2050
2051
TRTVNKHGDE IITSTTSNYE TQTFSSKTEW RVRAISAANL HLRTNHIYVS
2100
2101
SDDIKETGYT YILPKNVLKK FICISDLRAQ IAGYLYGTSP PDNPQVKEIR
2150
2151
CIVMVPQWGT HQTVHLPNQL PQHEYLKEME PLGWIHTQPN ESPQLSPQDV
2200
2201
TTHAKVMADN PSWDGEKTII ITCSFTPGSC TLTAYKLTPS GYEWGRQNTD
2250
2251
KGNNPKGYLP SHYERVQMLL SDRFLGFFMV PGQVSWNYNF MGVRHDPNMK
2300
2301
YDLQLANPKE FYHEVHRPSH FLNFASLQEG EIYNADREDM YA        
2342
 

Show the unformatted sequence.

Checksums:
CRC64:782658074BFD7D37
MD5:f2626b1163a037506ac5022113252cbc

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;