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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A0A1W2Q6C2_RAT (A0A1W2Q6C2)

Summary

This is the summary of UniProt entry A0A1W2Q6C2_RAT (A0A1W2Q6C2).

Description: ADAM metallopeptidase domain 11 {ECO:0000313|Ensembl:ENSRNOP00000076197}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 778 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 24
low_complexity n/a 10 32
disorder n/a 28 82
Pfam Pep_M12B_propep 50 193
disorder n/a 118 138
disorder n/a 174 176
disorder n/a 183 185
disorder n/a 222 236
low_complexity n/a 222 233
Pfam Reprolysin 243 442
Pfam Disintegrin 457 530
Pfam ADAM_CR 535 651
Pfam EGF_2 681 713
disorder n/a 715 733
transmembrane n/a 739 762
low_complexity n/a 739 757
disorder n/a 773 778

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0A1W2Q6C2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRRLRRWAIA ALLLLPLLPP PGLGALGPSG ALHWRSSAHM GSPESPEGPE
50
51
VTEPSRLVRE SSGGEVRKPQ LDTRVRQDPP RGTPVHLAQV SFVIPAFDSN
100
101
FTLDLELNHH LLSSQYVERH FSREGTRQHS TGAGDHCYYH GKLRDNPHSF
150
151
AALSTCQGLH GVFSDGNLTY IVEPKEMAGP WGPPQGPLPH LIYRTPLLPA
200
201
PFGCREPGCL FAVPAQSAAP SRPKLRRKRQ VRRGHPTVHS ETKYVELIVI
250
251
NDHQLFEQMR QSVVLTSNFA KSVVNLADVI YKEQLNTRIV LVAMETWADG
300
301
DKIQVQDDLL ETLARLMVYR REGLPEPSDA THLFSGRTFQ STSSGAAYVG
350
351
GICSLSRGGG VNEYGNMGAM AVTLAQTLGQ NLGMMWNKHR SSAGDCKCPD
400
401
IWLGCIMEDT GFYLPRKFSR CSIDEYNQFL QEGGGSCLFN KPLKLLDPPE
450
451
CGNGFVEAGE ECDCGSVQEC SRAGGNCCKK CTLTHDAMCS DGLCCRRCKY
500
501
EPRGVSCREA VNECDIAETC TGDSSQCPPN LHKLDGYYCD HEQGRCYGGR
550
551
CKTRDRQCQA LWGHVAADRF CYEKLNVEGT ERGNCGRKGS GWVQCNKQDV
600
601
LCGFLLCVNI SGAPRLGDLG GDISSVTFYH QGKELDCRGG HVQLADGSDL
650
651
SYVEDGTACG PNMLCLDHRC LPASAFNFST CPGSGERRIC SHHGVCSNEG
700
701
KCICQPDWTG KDCSIHNPLP TSPPTGETER YKGPSGTNII IGSIAGAVLV
750
751
AAIVLGGTGW GFKNIRRGRY DPTQQGAV                        
778
 

Show the unformatted sequence.

Checksums:
CRC64:FE38336A31D73623
MD5:56ef699896a703bf72958f743dabd9c9

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;