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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ACSA_METTP (A0B8F1)

Summary

This is the summary of UniProt entry ACSA_METTP (A0B8F1).

Description: Acetyl-coenzyme A synthetase EC=6.2.1.1
Source organism: Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) (Methanosaeta thermophila) (NCBI taxonomy ID 349307)
Length: 659 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam ACAS_N 41 95
Pfam AMP-binding 96 539
disorder n/a 216 218
low_complexity n/a 227 236
low_complexity n/a 546 563
Pfam AMP-binding_C 547 625

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0B8F1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAETAKTAVL QEETRIFNTP QWIIEYSNSY QWMKKKGFKT EKEMREWCAQ
50
51
NYLDFWDEMA QTYADWFKPY TQILEWNPPY AKWFLGGKCN VAHNAVDRHA
100
101
KSWRRNKVAY YFVGEPVGDT KTITYYQLYQ AVNKMANGLK SLGVKKGDRV
150
151
SIYLPMIPEL PITMLACAKI GAIHSVVFSG FSAGGLQSRV TDAEAKVVVT
200
201
SDGFYRRGKP LPLKPNVDEA VQNAPSVEKV VVVKRVGLDV PMKEGRDIWY
250
251
HDLVKDQPAE CYTEELDPED RLFILYTSGT TGKPKGIEHA HGGFCVGPAY
300
301
TTAWALDVHE EDVYWCTADC GWITGHSYVV YGPLCLGATS ILYEGAPDYP
350
351
DIGRWWSIIE EYGVSVFYTA PTAIRMFMKA GDQWPKKYNL KSIRILASVG
400
401
EPLNPEAYVW FRNNIGGGQA PIIDTWWQTE TGCHVIAPLP MTPEKPGSVA
450
451
FPLPGFNTDI YDEDGNSVPL GYGGNIVQKT PWPSMLRAFF RDPERYMKEY
500
501
WQMYWDIKPG TYLAGDKATR DKDGYWWIQG RIDDVLKVAG HRISNAEVES
550
551
AAVSHPAVAE AAVIGKPDEV KGEVIVAFII LKEGVQESED LKKDIAKHVR
600
601
SVLGPVAYPE IVYFVKDVPK TRSGKIMRRV IKAKALGKPV GDISALANPE
650
651
SVENIPLIV                                             
659
 

Show the unformatted sequence.

Checksums:
CRC64:E714A49C59FB871A
MD5:07c3f1475c73e3dd28e2b0059d8d99e3

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;