!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at pfam-legacy.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DP2L_CENSY (A0RYM0)

Summary

This is the summary of UniProt entry DP2L_CENSY (A0RYM0).

Description: DNA polymerase II large subunit {ECO:0000255|HAMAP-Rule:MF_00324}
Source organism: Cenarchaeum symbiosum (strain A) (NCBI taxonomy ID 414004)
Length: 1112 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam PolC_DP2 21 865
disorder n/a 298 299
disorder n/a 304 305
low_complexity n/a 446 457
disorder n/a 447 448
disorder n/a 453 455
disorder n/a 517 522
disorder n/a 524 526
disorder n/a 537 539
disorder n/a 545 555
disorder n/a 574 582
disorder n/a 584 595
disorder n/a 603 608
disorder n/a 694 697
low_complexity n/a 820 831

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0RYM0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSGGDVEEYL RGADMPEEYR RYYSSLSGGT YDIFEKAASA KSNLADSSGM
50
51
VEPKIAVDLS DRVAKMHDLD IAGPLRELLA TKGKELAALM LAKEIMDGKY
100
101
LPEADIEKRI DSAVRVGLAV VTEGVTIAPL QGIADVITKK NKDGSEYLSV
150
151
SIAGPMRSAG GTESAVTMLI ADYVRRQAGL AEYQADSLDD ETGRFIEELR
200
201
IYEREVGSFQ FHVLDEDIRA VISHLPVELD GVDTDPYEVV NHKGMSRIQT
250
251
DRVRGGALRV LNDGLIGRSK KLLKRIELYG LDGWEWLAEL KGAVQTGENK
300
301
EDAAAKRMRE VITGRSVLSM PNRLGGFRLR YGRACNTGYT SVGFHPAVAE
350
351
ILDHTIAVGT QVKIDIPGKG ATVAFVDTIE APTVRLAGGD VVKIRDVAHG
400
401
IELKGSIERI LHLGDMLISF GDFLENNAQL VPSGYVEEIW KMDMEAAGAA
450
451
QGSPSSADEA VRISRELGVP LHPRYLYYWD QISHEELAML LSPLDKGDAI
500
501
SYPAACKPVL EKLGVPHKAG PEGPVLEGDE ARIFRELILD NPPGPDASAP
550
551
VPELISRSSG ITIRDKFSTS IGVRIGRPEK AAPRQMRPPT HCLFPVGGTG
600
601
GPTNNLLKSA ARPGFSADIL SRRCPGCGEP SISIRCWACG ERTAVERTCM
650
651
QCGTDVDGEE CERCGRPGLA HSRVEFPLKK MLVSAQEKTG VRAHDPLKGV
700
701
KELAHQDRIA EPLEKGLIRQ SRSLTVFKDG TVRFDATNSP MTHFKPSWIG
750
751
TSAEKLRELG YETDVDGKKL EGPDQLVELR MQDIVIPLEG AKYLVSACGY
800
801
IDAELDKLYG APPFYKVPDL GGLIGHLVVG LAPHTSVGVA ARIIGYTETH
850
851
VCFGTPNWHS AKRRDADGDA DSIILLMDAL LNFSRHYLSD RIGGLMDAPL
900
901
LIQPLVLPHE SQSQAHNIEV VKRLPPGFYE AAAARKKASE VGCVEIVKSR
950
951
LETAGQFGGY HFTHGTSSLT TSRPRSAYST LGSMLDKLDL QIRNANLIAA
1000
1001
VDAAEIISNV ISTHLVPDIM GNLRAYARQN FRCTACGKSY RRIPLAQRCS
1050
1051
CGNGLIQTIT RASVEKYLKL AKRLVNEYDV GAYQRGRIHA LSDEIELVFG
1100
1101
KGGGDQALLT DF                                         
1112
 

Show the unformatted sequence.

Checksums:
CRC64:BA05392302C4ECF4
MD5:750e101312ddfe3365b09497f21c2df1

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;