Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: EFCB5_HUMAN (A4FU69)

Summary

This is the summary of UniProt entry EFCB5_HUMAN (A4FU69).

Description: EF-hand calcium-binding domain-containing protein 5
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1503 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 1 33
disorder n/a 36 61
coiled_coil n/a 46 73
disorder n/a 63 86
disorder n/a 112 121
coiled_coil n/a 119 149
disorder n/a 130 131
low_complexity n/a 136 151
disorder n/a 137 139
disorder n/a 144 148
disorder n/a 194 196
disorder n/a 259 262
disorder n/a 264 266
disorder n/a 476 683
disorder n/a 690 691
disorder n/a 723 744
disorder n/a 746 748
disorder n/a 913 916

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A4FU69. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNESASQEEL RPAQENRKED KERKWNLTEV KELHETLQSV PDVPVKEDTN
50
51
SVVEKAMDEI KSQELNLEGQ RKISPGSIKD SKTEASGNIA IRKSAKVIFA
100
101
LDETELKSKP EHTWKKNLFE RMEARAQAMQ QKIIDKENLK KELEKKAEKK
150
151
LPRDNLAKEW FNTDSMTLNN TAYLLDKLLP TLVPGVENML TQVEKKKVLT
200
201
EADTPSKFDP INYLGEYLIR NNPNYIKDPG MSGYQRLMKE VTEDLKIYVP
250
251
DTICNRVSKM KENVKQNRKQ RESIDKIIVK VANTRKQALQ EQFDEWILDP
300
301
KGMIPKSVIQ NVLQEFFQNP DFKLGSHCKQ LDITDSTEPR LNKMEFTEYI
350
351
SSHIKDLKSE MFEELLKHLC HSADEFREVI KADMRRQMFA ELFLHCDHGK
400
401
VGFLDRQRTL ALLELFYDHS SQMLRSLLRN PRQWPFIEFE EINLTELWGD
450
451
MDNQKHIYEG FDKVLLEMNT LLSANHASKT QSKLLESPDQ PKLNEQRTST
500
501
PSPNPPEQQR GVTAEQGPQR ISIEEQQQGK KPTAEQELYI ESVIEPGTHT
550
551
ESTLEQGSSR RLLTEQETHR ESTTEQGQHK GSIEGQGPRR VSVSEQGSSR
600
601
ESVAEQGSRR ESIAEQDRHK GSVAEQGSRR MSAAEQGSLR ESVIEEPYQK
650
651
SEQGPYGEII SEEQEDIGST SQSRKDSILK STKYGEPITS EYIEVPLQEK
700
701
RSWEQTYEEE IFLSSELQEE VPTLSRKDHF PETTKKEVQK DKPCEPKSQK
750
751
IEGKSWSGEF FTCNWKMKYV TFEDEEQANL IYGNSRFTDL HSIIRNIQSC
800
801
KEVKGRTAFN GVSFNLLQFV QLLETFVGED APLSVSETLT SFFKEGYVET
850
851
EQEKMNALEQ FSQNAFQVRQ RLLLEAIFQK WDSDGSGFLD LKEVDELLYT
900
901
YKEGMEKESM KKAKLHIQFP KPHPGHEVRL SSKQFQNYIE LVVSELRGNE
950
951
DQVLESVVEF LMNALERSHI ESLRNSARRK WLHQIQCAAE TSGVSLEPVY
1000
1001
SETFKALMQD AEAHGNKKIS AHISLLEENL LLPEKGNVLL RNVACTLDDA
1050
1051
QFVLNRVLYR DMKGISFTVV DEGKPIHVPQ VQYHGNIFFW NQSRNKHDYN
1100
1101
GSFLALPLQD AYMRIFGVLA VDTLRDPHEI NIFLPHEIRF YQGVANVFST
1150
1151
AYHYVHSREH ILHIVITGIG WLYDVTSSIT SITTYFVEPS PAQDSDYVLR
1200
1201
NMMVTGQLGL TEIHKNPPTI HRKSCIFRDF LFKCTDSSEV VLASACGETH
1250
1251
IVVPLRERTG EALGVLDFNI GQNRMLLCQE YKDLQKMMKV VQVACYEILG
1300
1301
EFSGEIKKKY ILEIENVREV QRAGILFFRI MLLELQESIQ LLNSMEFVSL
1350
1351
LLYDHTLVTE PNSPQDSKSM ELEANVKLVR DILKAVILFF HPELEFSSDF
1400
1401
GSWDKCKFYV NKYLVNNICA FDPTAKHVEV NVQLIDEYIR DHSRTEVWKF
1450
1451
GNVVIEHLYH WIHICSALMK ITKQLNSGIT PPLPSKTDNY MYAKMPGEGL
1500
1501
QEK                                                   
1503
 

Show the unformatted sequence.

Checksums:
CRC64:907EED07E7C17EB7
MD5:0cdceaa6708f5db0045ac36ea8854fae

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.