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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A4I136_LEIIN (A4I136)

Summary

This is the summary of UniProt entry A4I136_LEIIN (A4I136).

Description: General transcription and DNA repair factor IIH helicase subunit XPD {ECO:0000256|ARBA:ARBA00014344}
Source organism: Leishmania infantum (NCBI taxonomy ID 5671)
Length: 813 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam DEAD_2 72 246
coiled_coil n/a 246 273
Pfam HBB 259 406
Pfam Helicase_C_2 533 709
disorder n/a 798 813

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A4I136. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKLYVEDVLV VFPYEYIYPE QLDYITELKR GLDKGGHMVL EMPSGTGKTI
50
51
SLLSILVAYL HHHAHEKRKV VYCTRTVEEM VKTMGEMRKL LKHWEAEGEQ
100
101
LRPLRGLCLT AKKNLCIETS VASLIHPDEV DAGCRSITAP WQQEGRCGYF
150
151
DTLAQAPLEL PPGVYSLDDL KDFGEQHHVC PYYLVRKALP VVDIIVHSYL
200
201
YMVDPVVSEV TKEFLNENTI VVMDEGHNVD DVCIEAMSLI LTKKDSLDAK
250
251
QNMKDLSKEL DHLKATNRQM LQDEYDRLVN GLAMTEMARD PEQRALVEAP
300
301
AIPANVAEGA IPASLRQANH FLAFMQRLVD FTHRIVARIT RTYVADPLTF
350
351
LTKLKEECAL EISHFRYLSE RLKVLLTTLQ VTNAGKYRPV ALIAQMYTLL
400
401
SMYYTDDRYE KPGFVVVCEA FDPTRPQIPD PVIRTVCVDA SLALRDTFAR
450
451
YRSVILTSGT LSPMDIYPKI LGFTPAISKS FQMTLSRKCI APVIVTRSSE
500
501
SVSITAEEVT SSFKVRTNPT AQALVTSAYE SLLLELAKTV PDGMVCFFTG
550
551
YQYMGEVLLA WHSSGFLQKL AKHKLIFVET QGVEETSVAL ANYRRACDIG
600
601
RGAIFMSIAR GKIAEGIDFD RHYGRAVVMF GVPFLPPNDE PLRQRMHWME
650
651
VCLGISESEF RNFDAMRQAS QCIGRVLRNK TDYGMMLLVD KRFALNDKVK
700
701
KIPRWIVQCL KNNTNLSVDA AVAVARGFFK EMAQPWEHEK DLGTTLLSKE
750
751
TLRRMGRLSS SAAKYASFSE TLAAENVSTV TAPTTEFEEI VGITAVREPG
800
801
AGSRKRKRDG ERE                                        
813
 

Show the unformatted sequence.

Checksums:
CRC64:153875872D7DD1FF
MD5:e7451925d93c2b9bf11e50064f59a366

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;