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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A4I1A3_LEIIN (A4I1A3)

Summary

This is the summary of UniProt entry A4I1A3_LEIIN (A4I1A3).

Description: DNA-directed RNA polymerase subunit beta {ECO:0000256|RuleBase:RU363031}
Source organism: Leishmania infantum (NCBI taxonomy ID 5671)
Length: 1616 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 57
low_complexity n/a 2 20
low_complexity n/a 23 38
disorder n/a 103 126
disorder n/a 133 138
disorder n/a 149 151
low_complexity n/a 162 176
disorder n/a 223 228
coiled_coil n/a 255 289
disorder n/a 294 299
low_complexity n/a 297 308
disorder n/a 303 305
low_complexity n/a 409 426
Pfam RNA_pol_Rpb2_1 433 797
low_complexity n/a 693 705
Pfam RNA_pol_Rpb2_3 858 922
Pfam RNA_pol_Rpa2_4 972 1042
Pfam RNA_pol_Rpb2_6 1107 1506
disorder n/a 1349 1353
disorder n/a 1491 1500
low_complexity n/a 1501 1513
disorder n/a 1502 1509
Pfam RNA_pol_Rpb2_7 1508 1610

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A4I1A3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSSRSSHYSA KSLSSSAGES MVTSHSTGSS SRHRRTGTAC IHEPRAPPIK
50
51
MTAMERLQHI RNSITRLKYI CERQYHTAAL DQASEASVTP FFERLRKKLS
100
101
KLEFSRSHIG TPETGGPQQL KYMAKESRQL MSTAQEVVRD TANTSATATC
150
151
VYEGMQHHHM QEAMAELEEL SALLAERPNE QLSRVNADLL ADLVAFHIDE
200
201
FDAFMSLRVE AFAREMQSEG AFYTGPVMTD ASQKATPVGV CSAVLLDVAV
250
251
GVRPARSARI VLEHARHQIN KVENRLHAAD IALQECQRAG EVAADGQQRQ
300
301
QAEVQRREFT IMKERISHAL RQLDRAQQAW LEEEQSIFTR AASGSHDLAA
350
351
LMQTKHLREA EVIEEVQRLH DQTIHACLPF ATPQYHRRYG ETYGQPCHVR
400
401
LGFHFLPDAN TAAEMAAAAG SANAAAPSSL MLRTFSTEYF ALMRQLRVAP
450
451
ADYDTYDYLV PSKEQFWVNF ASFPEMVKGA RCALRNVDAR LDHFRALEEQ
500
501
KEVGGYFIMN GGERILRALL MQRCNVPINI YREKFVTQGP HFSAKAVVIR
550
551
CKRPSGLTAQ NYFYYTTQGE VIFSFARKVV WHLPVPLLLS ATSTQSVSAV
600
601
ELQRLLTIGM PDGNHAARVE ALLQHHRRKP YGDLRHFIDY ITVLGRMYRE
650
651
YHQNSSTFHF LPLYAKGSTC QHDAWYGMFM LRRHVLPHLN SCDAATPDLA
700
701
PDATAQQLLA WLSPALLAEL DRKFDAMIAI TRQLYLFIDG AVEHQGNDVP
750
751
AYQELFTVSQ VLMGAFEVCL NRYMRGFVYR FARHLPAALF RRILHLRTLL
800
801
PPVDAEDAMR QVRQFAEFCG RHGGSDPLDQ LARLLVTGNI NLNREEDFYC
850
851
PQTSGWVVMA EHLNFYRFFE QLRCVHRGKT IADMRSSEVR KYPCEAYGFI
900
901
CMVQSPDGED CGVLNHLSLS TISSNSPDAA MTAQLREIVC KAVPGVRSRA
950
951
THSTVVDQLC ETVPVWMEGE LLGYLSPADA VEAAARLRQR KALTLRSQVH
1000
1001
VTGIVRRKDA SPLHTLEVVY VAPKNKDPAG LYVFYDCGRL MRPVQRLESS
1050
1051
VRKDATHLPF PLVFIGTWEQ SWLDIAAVPS DPLDAVVQLN RKYEYMEQNG
1100
1101
TNLISLTSAT IPFFEHNCSP RNLFQCGLSK QSSGTQLQAL AWRKEAKLFR
1150
1151
TYCPQRYISR TLPMDYYGLD DVNLGVNAVI AILAYTGYDM DDAVIINSTA
1200
1201
AQRGMLTAGV TVAKIVTASG KGSDKDDVFV FHNLLSTGER FTAELEANGL
1250
1251
PPKRANASLD AFSFDRDHKY PGLRDNNDVY CCAKRVERVD PFTNKSVYEY
1300
1301
TRHHATKWRH FDKGEDAWVQ QVIPLVYSGP DPTSVLMIFR IPRPPTVGDK
1350
1351
FSSRHGQKGT LPLHIRSHNL PFATASGITP DVIINPHAFP SRMTVGMVLE
1400
1401
IMTAKVGAIE GRFIDHSAWS TVDEQPRVAE LIGEALVKAG YNRYGREHLI
1450
1451
DGISGEEMKA DVFMGICGYQ RLRHMVSDKW QARARTDAHT YRAVTKTGQP
1500
1501
VKGRKRHGGV RVGEMERDGL LSHGISEVVV DRLLHVSDKT KAFICPRCGS
1550
1551
LLSLYERHAT EYGTWRTCRF CGAGADESTD SIAMVEIPQV LRLWAAELTS
1600
1601
IGVRVALKTS ELSDFI                                     
1616
 

Show the unformatted sequence.

Checksums:
CRC64:B7140FE8DDF99359
MD5:01f2da0b3d5f01831534be21e8a4fae8

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;