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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A4I2P6_LEIIN (A4I2P6)

Summary

This is the summary of UniProt entry A4I2P6_LEIIN (A4I2P6).

Description: Oxoglutarate dehydrogenase (succinyl-transferring) {ECO:0000256|ARBA:ARBA00012280}
Source organism: Leishmania infantum (NCBI taxonomy ID 5671)
Length: 1006 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 16
disorder n/a 28 32
disorder n/a 34 35
disorder n/a 37 39
disorder n/a 77 94
Pfam E1_dh 227 550
disorder n/a 492 494
low_complexity n/a 522 531
disorder n/a 567 569
disorder n/a 580 586
disorder n/a 611 621
Pfam Transket_pyr 629 848
disorder n/a 664 666
Pfam OxoGdeHyase_C 850 1005
disorder n/a 892 897
disorder n/a 953 957
disorder n/a 975 976
disorder n/a 985 989

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A4I2P6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MMRRALSGAV AVRASAMRSY TDARTIRKPN PYDQLVNAEN QHYVEDLMRQ
50
51
YEADSALVDP SWVPVLEAIR SGSDDSPVVA TFSRPTDAKS LSEKQRHDNM
100
101
RLSWMIREYE RFGHHMANVD PLSGYHADNR ILGSRTLAPE EFGFTKDDLT
150
151
HVFNVTFGAS HEATFVSGGT AMTLQQIIDQ LRRLYCGPIG FEFMSSGFFE
200
201
LRNWFRQEVM DSLQPLPAEE RRLYYNDVVK ACGFEKFLQL KYATKHRFGL
250
251
DGGEALIPAL KAAILTSSDL GVQSAIIGMA HRGRLNVLAN VLRKSLRAIL
300
301
NEFEGRVAIE DAHLTGDVEY HLGKRKHVKL PNNKSIELDL LPNPSHLEAV
350
351
NPLVLGKARA RQIYTNDVEC TAVLPILIHG DAAFAGQGSC YETMGFCELE
400
401
NFHVGGTLHL VINNQIGFTT NPKDSRASAY CTDLSKVNNA PVMHVNGDDV
450
451
DACVKAAKIA ARFRQQFHHD IIIDLVCYRR YGHNETDLPD FTQPQLYNQI
500
501
RQHPSVVDIY TKTLIRDGVL TAEEAKAKDK EWEGVLRQAY DRMNSAQNFV
550
551
KVMPVFDPES ENTSADLSYA KIAATRVPPP VSAVDTGVET QTLRMAGLRL
600
601
ASIPKEMQKP HPVVERTYAA RKKGTEQGDA IEWCQAELMA LATLSMQGVP
650
651
IRLTGEDVER GTFTQRHAGI TDMKTNLKYF PVKTLSPSQA LITISNSSLS
700
701
ELGVCGFEMG YNMENTRSIT IWEAQFGDFA NGAQVIFDQF LSCCEEKWNE
750
751
HSSLVLSLPH GYSGAGPEHS SARVERFLQL SDDGDRVPSD FRHFPNDQAL
800
801
EIRIRRHNWQ VTYPSTPANY FHLLRRQGLR EFAKPLINFF SKARLRAPNL
850
851
SKLSDMTQGT SFKAVIDTAR AKDTVARKVV FCSGQIESIV NDAKAARQKE
900
901
TPGVHDDVVL VTVEQLAPFP WEQVADVMEK YAQRNLNTEF VWLQEEPRNM
950
951
GMWTHMRPRM NSLMHHLGLK QKRINVVSRP SAASPSTGYG SVHVAEEKKL
1000
1001
IAETLA                                                
1006
 

Show the unformatted sequence.

Checksums:
CRC64:18A1BF0137390DCF
MD5:c3618693907442aa52be750b01118752

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;