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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A4I4I0_LEIIN (A4I4I0)

Summary

This is the summary of UniProt entry A4I4I0_LEIIN (A4I4I0).

Description: Sec16_C domain-containing protein {ECO:0000259|Pfam:PF12931}
Source organism: Leishmania infantum (NCBI taxonomy ID 5671)
Length: 2158 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 1 289
low_complexity n/a 5 12
low_complexity n/a 72 95
low_complexity n/a 124 138
low_complexity n/a 140 163
low_complexity n/a 189 215
low_complexity n/a 228 250
disorder n/a 300 306
disorder n/a 309 332
low_complexity n/a 335 344
disorder n/a 338 488
low_complexity n/a 431 442
low_complexity n/a 450 462
disorder n/a 510 518
disorder n/a 521 1063
low_complexity n/a 569 587
low_complexity n/a 632 643
low_complexity n/a 674 689
low_complexity n/a 694 715
low_complexity n/a 725 741
low_complexity n/a 764 776
low_complexity n/a 778 789
low_complexity n/a 784 797
low_complexity n/a 806 833
low_complexity n/a 923 927
low_complexity n/a 965 981
low_complexity n/a 995 1006
disorder n/a 1065 1165
low_complexity n/a 1111 1122
low_complexity n/a 1118 1132
low_complexity n/a 1143 1161
low_complexity n/a 1186 1204
disorder n/a 1200 1204
disorder n/a 1270 1273
disorder n/a 1281 1291
low_complexity n/a 1362 1378
low_complexity n/a 1415 1447
disorder n/a 1432 1452
low_complexity n/a 1440 1457
disorder n/a 1475 1476
disorder n/a 1478 1479
Pfam Sec16_C 1488 1683
low_complexity n/a 1498 1515
disorder n/a 1552 1553
disorder n/a 1555 1603
low_complexity n/a 1555 1563
low_complexity n/a 1584 1598
low_complexity n/a 1647 1658
disorder n/a 1662 1683
low_complexity n/a 1668 1680
disorder n/a 1685 1686
disorder n/a 1688 1689
low_complexity n/a 1720 1734
disorder n/a 1741 1764
low_complexity n/a 1742 1756
disorder n/a 1790 1793
disorder n/a 1802 1807
disorder n/a 1818 2158
low_complexity n/a 1825 1833
low_complexity n/a 1839 1843
low_complexity n/a 1887 1898
low_complexity n/a 1968 1978
low_complexity n/a 2038 2052
low_complexity n/a 2050 2064
low_complexity n/a 2132 2149

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A4I4I0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSGGPPPPPP PPRTGAAEGG EVHPLSMFSK RPAGPPGTPY SSVVDPAAAR
50
51
RVNMLSAYSQ YANPAAGARA LPPASTGSGY APPPGPADPA APPPPVRPLV
100
101
ATGTPEADKG HPSPSPAQLT LGQPSSSPPP PPPCAAPPKT AALNTPWTPP
150
151
PPPLSPATSA GGPRVGGASR YAVPNYAFGG EANTSVAGPP PPAPQPAAPL
200
201
AASPPLPPPP PAALPSGVMH TMLEHTEPEA PSHPPPAAFS SPSAPAAAPA
250
251
GPLLATRVSG VALGRPASSR NSSNGRQSPR DLSEFTGHWV PSRISKEYNT
300
301
FLAEVNSPSE TAAAAAVVHH SRPSSRGSSI LEGVAAASAA ALEAGGHRTP
350
351
SAPGHAPNIS SGLRRSVPAF LQPGGGDSVA QRTVRAASSR VDSTTTASRG
400
401
RKLLEAALTA RGARHAPLRH TSFSSLAAHP QQQSSASVQK SQGAPVRGKE
450
451
AGAAPAEHSA GARLEMRDQW SSAPTHRSSG NDGSAATDAS LLVPGLATLC
500
501
TGSASLGTGY SFSSRSVRPT MGGNGDFLTC DTALLSNARA GDPKGESASR
550
551
DGPLQADGPL RRADAEHVSS SGHAGDAAAS SHPSAPPRNP NGLIAGGMTV
600
601
SGAEAPANAH THNPRFDARG SLPRPADEPP QSDLSADDRS ASRQEHRSAF
650
651
MTGSDPTLAT TTLVNPFRAM TRKSGGGGDT AASPAPPPTV SREQLSCQQQ
700
701
QWQDPQQQPR QKLLLHDAPH SGFHSGAPPS APSPSYPDAE ANLPEKLSSP
750
751
KDITTTEDAG TAGPPLPPLP QQQQPLFAAA NGDTTTATAP VTGFTTPRGG
800
801
GAGSVPRAPP QRQQLPLPPS NSSSSNVPPN MSRGLYAASP YVRDEDARAV
850
851
VDESPIPQRP LPFDSVPQLE ATPMATAEQD EGEFGATDSG ALDYTHNNGA
900
901
HAVRRSMQDD LTEEKGAAGQ YQPPPPPRNG LHAAPPLSPA QKRGAANPFS
950
951
AILTQVHPKV LHASQQQPPP QPTHEPQAQE QRQEGPTGPS AHLIPQPSGP
1000
1001
PPPVLPTRTI SKSSALPLLP NPGFPCSTNI SESPLSKDST PALKPSPRNV
1050
1051
ADTWSCHDCP SSSNPFLEPD ENFLFTPSNG LLPDAANTST NSTSRQRPHQ
1100
1101
ALMGSLDSVQ SAPAHHEPPP PSKDDAAPPM ASNSTTAPLL NFAGDGGAPG
1150
1151
TTTARTPGGA TLVNPFSKSA PNSNCYLSAT TVSINGSGAL SGGASLTGSF
1200
1201
AGGAVRKKSR RSGAPCFAIF VGGATLLPGV QGDNSSERRG FPCIAACFNN
1250
1251
PISWSPLIAN SARSPLVQPI TSASSRTGSV RTTSLSGAAR ANTSPVPRPL
1300
1301
GVGALGGNIG ICLSFCSVTE ALTARGSMVD RKGIRGTEYG RRYVRALTDA
1350
1351
VLPCALLADQ WATGDAATGA VVAGVMDALK GCVPAPLGEV VEVMLMDALP
1400
1401
QKDGGGFVWK DNGGRRLAEL LTAAAQADAR RRAATARSRS ATAHPAAGAS
1450
1451
ATSATEANDA LMAISPLNPV TSAARCDSKE RAAALRRVED LLCTGQRVEA
1500
1501
VETALEAHLH AHALLISMMC PTKDLYLRSV QAVMQQELSV TSPLAHAYSM
1550
1551
FNEMPLPPLV PPPSKADEED EGATALGEGR SISEAAQHQE QQHKRQQQMF
1600
1601
LRNQEMLQQT WRRHAAILLA NFTRHSGNGL LQLATTLQQV NLVVEAHTCL
1650
1651
LLLHLTPLGM AGPARAGAEP LPPASSLSPE CVEDLLPRPD QRQVMEEIRR
1700
1701
RIGVVGGTYH PTRGCRASFL TPVTTLLTQL VQLVSARLDA RAPPLSPPES
1750
1751
AEPPVPFHGL PHGQPRSDIG YRMMQVLWLR ELGLGKESAQ ALHALLQRMP
1800
1801
PPLAFSLRVP PRTLNELVYL FGGVPPPSPQ QPPDALDGAA AAARGESVPE
1850
1851
SEATTQQPSP NAYAGSPSHS REVLPQNADD EADKAPSTSR STLTRSTSEV
1900
1901
HHTGPLPQRN PQQRQAPTPQ HLSLLNRALL PSSPPGTATS LLTRDQRAAA
1950
1951
LQPLERPEPP SDGKPGNASA KAATAPAAGK LKQPAPRRSR SLDVLRNFFR
2000
2001
RGHSEAAGEE KSDEAKPMHL DTEKPPAFDP VTGRWLFEET EEEKRLRELA
2050
2051
KAGPPKMAPK AAGPTSAPVA SAAAWGPSPS ESAPLQRPGT GKEPQPGNAR
2100
2101
PGPGAPTPVH AGGGMLAPRP SGGAPAIAGR DAPPPTMAGR GAARPGGRPQ
2150
2151
YVDMFNTN                                              
2158
 

Show the unformatted sequence.

Checksums:
CRC64:3A489DA2A7E15E07
MD5:35bbb30aedc560a9e2b1dcbad83eb8a5

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;