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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TGFA1_DANRE (A4IG72)

Summary

This is the summary of UniProt entry TGFA1_DANRE (A4IG72).

Description: Transforming growth factor-beta receptor-associated protein 1 homolog
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 863 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam CNH 33 292
low_complexity n/a 383 396
Pfam Vps39_1 448 550
Pfam Clathrin 568 728
low_complexity n/a 590 603
coiled_coil n/a 634 654
Pfam Vps39_2 739 847
disorder n/a 855 863

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A4IG72. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSVKAFDLVP AVEREQVMGE KVRINIECIE CCGQHLYLGT NDCFIHHFLL
50
51
EEHTTAKGKL AFNAQKLLHK YLGLKKPVVE LKAASALERL IVLCDSAITV
100
101
VDMVTLEPVP TGGAKLKGVT AFCINENPVT GDAFCVEMAV VLARRRAVQI
150
151
CTVHEDRVQM LKEVTTPEQP CALSLDGYNI CLALSTQYMI LNYSTGASQD
200
201
LFPYDCEERK PIVKRIGREE FLLAAPGGLG MFANAEGISQ RAPVSWSENV
250
251
IAAAVCFPYV VALDEGFVTV HSMLDQQLKQ TLSFRDGQLL QDFEGKVVVA
300
301
SSKAVYMLVP LPLERQIQDL LASHRVEEAL TLTEAAQRNI PKEKYQILHR
350
351
RILQQAGFIQ FGQLQFLEAK EHFRKGQLDV RELISLYPLL LPASSSFTRC
400
401
HPPLHEFADL NHLTQGDQEK VQRFKRFLIS YLHEVRSSDI ANGFHEDVDT
450
451
ALLKLYAETS HESLLDLLAS ENACLLADSA PWLEKHHKYY ALGLLYHYNG
500
501
QDAAALQMWV KIVNGDLQDS TRPDLFEYVV DFLSFCSNLD LVWRHADWAL
550
551
QKDQKIGVQI FTKRPTSEER RGQLNADDVI TYLQKHSQAL LLYLEHLVLE
600
601
KKLQKEKYHT HLAVLYAEKV LGLISRPSTS EEQLSAARQK LQRLLKESNL
650
651
YRVQLLLGKI QDSELLLLER ATLHGKLEEH DKALHVLVHQ LKDSSAAEEY
700
701
CSWASASQDS SYRQNLFHQL LSVYLDPDVP GGAQTVAAVD LLNRHAEVFD
750
751
AVRVLKLLPE DWSLPLLRPF LCGAMRATVH ARCTSQVALG LARAQNLQLL
800
801
HDRLKYRGGP VLVSEKKGCQ LCHNTFSEPD CACLPGGTPV HINCVAKKAL
850
851
DLPHENAHHS NHT                                        
863
 

Show the unformatted sequence.

Checksums:
CRC64:77147BF06E4ED5E6
MD5:dda861f359f5540deb6f1d694be1866b

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;