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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SERC4_HUMAN (A6NH21)

Summary

This is the summary of UniProt entry SERC4_HUMAN (A6NH21).

Description: Serine incorporator 4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 518 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Serinc 35 493
low_complexity n/a 36 47
transmembrane n/a 62 80
transmembrane n/a 118 140
low_complexity n/a 130 141
transmembrane n/a 152 170
low_complexity n/a 156 165
transmembrane n/a 182 207
transmembrane n/a 219 246
transmembrane n/a 258 276
transmembrane n/a 288 306
transmembrane n/a 338 356
disorder n/a 398 410
transmembrane n/a 427 447
transmembrane n/a 467 490
low_complexity n/a 478 488
low_complexity n/a 499 509

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A6NH21. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVGAKAGPSP GTSLGLAQQH SGGSSVLVKS PFCQVCCCGP APCASCCHSR
50
51
WPSLTASTCS RLFYILLHVG ASAICCLLLS RTVVERVWGK THRIQMPSGL
100
101
CAHLFGLSDC PVLSGSGAVY RVCAGTATFH LLQAVLLVHL HSPTSPRAQL
150
151
HNSFWLLKLL FLLGLCAIAF CIPDEHLFPA WHYIGICGGF AFILLQLVLI
200
201
TAFAHSWNKN WQTGAAQDCS WFLAVLLATL GFYSMAGVGA VLLFHYYTHP
250
251
AGCLLNKMLL SLHLCFCGLI SFLSIAPCIR LKQPRSGLLQ ASVISCYIMY
300
301
LTFSALSSRP PERVILQGQN HTLCLPGLSK MEPQTPDISL AMLSASIMYA
350
351
CVLFACNEAS YLAEVFGPLW IVKVYSYEFQ KPSLCFCCPE TVEADKGQRG
400
401
GAARPADQET PPAPPVQVQH LSYNYSAFHF VFFLASLYVM VTLTNWFSYE
450
451
GAELEKTFIK GSWATFWVKV ASCWACVLLY LGLLLAPLCW PPTQKPQPLI
500
501
LRRRRHRIIS PDNKYPPV                                   
518
 

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Checksums:
CRC64:93A6224C102565AE
MD5:316dc1efab548a0c2a2c5fcdfa8c192a

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;