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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SHSA7_HUMAN (A6NL88)

Summary

This is the summary of UniProt entry SHSA7_HUMAN (A6NL88).

Description: Protein shisa-7 {ECO:0000305}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 538 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 19
low_complexity n/a 3 14
disorder n/a 19 26
low_complexity n/a 29 38
low_complexity n/a 44 61
disorder n/a 50 73
low_complexity n/a 56 79
Pfam Shisa 79 144
disorder n/a 139 178
low_complexity n/a 140 168
low_complexity n/a 162 183
disorder n/a 212 218
disorder n/a 221 275
disorder n/a 277 282
disorder n/a 291 292
disorder n/a 306 307
disorder n/a 309 310
disorder n/a 333 339
disorder n/a 344 354
disorder n/a 358 396
disorder n/a 400 402
disorder n/a 411 538
low_complexity n/a 428 441
low_complexity n/a 443 456
low_complexity n/a 454 471
low_complexity n/a 467 486

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A6NL88. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPALLLLVLL ASSAGQARAR PSNATSAEPA GPLPALLAHL RRLTGALTGG
50
51
GGAASPGANG TRTGPAGGAG AAARAPPPAE LCHGYYDVMG QYDATFNCST
100
101
GSYRFCCGTC HYRFCCEHRH MRLAQASCSN YDTPRWATTP PPLAGGAGGA
150
151
GGAGGGPGPG QAGWLEGGRT GGAGGRGGEG PGGSTAYVVC GVISFALAVG
200
201
VGAKVAFSKA SRAPRAHRDI NVPRALVDIL RHQAGPGTRP DRARSSSLTP
250
251
GIGGPDSMPP RTPKNLYNTV KTPNLDWRAL PPPSPSLHYS TLSCSRSFHN
300
301
LSHLPPSYEA AVKSELNRYS SLKRLAEKDL DEAYLKRRPL ELPRGTLPLH
350
351
ALRRPGTGGG YRMEAWGGPE ELGLAPAPNP RRVMSQEHLL GDGGRSRYEF
400
401
TLPRARLVSQ EHLLLSSPEA LRQSREHLLS PPRSPALPPD PTARASLAAS
450
451
HSNLLLGPGG PPTPLRGLPP PSSLHAHHHH ALHGSPQPAW MSDAGGGGGT
500
501
LARRPPFQRQ GTLEQLQFIP GHHLPQHLRT ASKNEVTV             
538
 

Show the unformatted sequence.

Checksums:
CRC64:B64A8A543C64CF6B
MD5:ef94d799e067cf3087f21e6574a3c890

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;