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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DEN10_DANRE (A8E7G4)

Summary

This is the summary of UniProt entry DEN10_DANRE (A8E7G4).

Description: DENN domain-containing protein 10 {ECO:0000305}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 349 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam SPA 152 259

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A8E7G4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MATPELMLSL GLIEKDVNAD TLWVWCYPSI DADLREVMLR KCCLTLDNQV
50
51
LHTFVFGQFC RTWYYITTVE VQEPTVLKKV THFSIVVTAK DFNPEKYAAF
100
101
SRVLCRTYMK HGSPVKMMEG YIAVLTKGIC QSDENGSFLI KDYDVRKALL
150
151
AGSLKDVVSQ FGMETIILYT ALMLKKRVVV YHPRIEALLE FTRALPCLVW
200
201
HRKDWSILHP FVHLENDELE NLKVCTGYVA GFVDPEVKDR SDLFDVFVNL
250
251
PDSEITVSQN AKEAMSMGKL HKEIGNFIVQ AAEDADRSDA QVIKDISVKT
300
301
KEILSNLMSL ADHADNSKLT LECLKQGHYP PATENFLFHL AAAEQLLKI 
349
 

Show the unformatted sequence.

Checksums:
CRC64:102AB1CC9C50E98E
MD5:73c406aaa4b24af9c6835ed06ba0bf21

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;