Summary
This is the summary of UniProt entry ADA11_HUMAN (O75078).
| Description: | Disintegrin and metalloproteinase domain-containing protein 11 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 769 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 23 |
| low_complexity | n/a | 1 | 30 |
| disorder | n/a | 27 | 78 |
| low_complexity | n/a | 33 | 42 |
| Pfam | Pep_M12B_propep | 46 | 189 |
| disorder | n/a | 114 | 134 |
| low_complexity | n/a | 214 | 228 |
| disorder | n/a | 217 | 232 |
| Pfam | Reprolysin | 239 | 438 |
| Pfam | Disintegrin | 453 | 526 |
| Pfam | ADAM_CR | 531 | 647 |
| Pfam | EGF_2 | 677 | 709 |
| disorder | n/a | 711 | 729 |
| low_complexity | n/a | 734 | 752 |
| transmembrane | n/a | 735 | 758 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O75078. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MRLLRRWAFA ALLLSLLPTP GLGTQGPAGA LRWGGLPQLG GPGAPEVTEP
50 51
SRLVRESSGG EVRKQQLDTR VRQEPPGGPP VHLAQVSFVI PAFNSNFTLD
100 101
LELNHHLLSS QYVERHFSRE GTTQHSTGAG DHCYYQGKLR GNPHSFAALS
150 151
TCQGLHGVFS DGNLTYIVEP QEVAGPWGAP QGPLPHLIYR TPLLPDPLGC
200 201
REPGCLFAVP AQSAPPNRPR LRRKRQVRRG HPTVHSETKY VELIVINDHQ
250 251
LFEQMRQSVV LTSNFAKSVV NLADVIYKEQ LNTRIVLVAM ETWADGDKIQ
300 301
VQDDLLETLA RLMVYRREGL PEPSDATHLF SGRTFQSTSS GAAYVGGICS
350 351
LSHGGGVNEY GNMGAMAVTL AQTLGQNLGM MWNKHRSSAG DCKCPDIWLG
400 401
CIMEDTGFYL PRKFSRCSID EYNQFLQEGG GSCLFNKPLK LLDPPECGNG
450 451
FVEAGEECDC GSVQECSRAG GNCCKKCTLT HDAMCSDGLC CRRCKYEPRG
500 501
VSCREAVNEC DIAETCTGDS SQCPPNLHKL DGYYCDHEQG RCYGGRCKTR
550 551
DRQCQVLWGH AAADRFCYEK LNVEGTERGS CGRKGSGWVQ CSKQDVLCGF
600 601
LLCVNISGAP RLGDLVGDIS SVTFYHQGKE LDCRGGHVQL ADGSDLSYVE
650 651
DGTACGPNML CLDHRCLPAS AFNFSTCPGS GERRICSHHG VCSNEGKCIC
700 701
QPDWTGKDCS IHNPLPTSPP TGETERYKGP SGTNIIIGSI AGAVLVAAIV
750 751
LGGTGWGFKN IRRGRSGGA
769
Show the unformatted sequence. |
| Checksums: |
CRC64:EEB091EB6730AC36
MD5:16d47bda874c6d631ac475266fd140bd
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.