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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: B8A5L2_DANRE (B8A5L2)

Summary

This is the summary of UniProt entry B8A5L2_DANRE (B8A5L2).

Description: F-box protein 10 {ECO:0000313|Ensembl:ENSDARP00000121445}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 1015 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam F-box-like 3 51
disorder n/a 259 260
disorder n/a 262 263
disorder n/a 290 322
disorder n/a 324 331
disorder n/a 333 379
low_complexity n/a 352 376
Pfam Beta_helix 417 570
low_complexity n/a 427 435
Pfam Beta_helix 557 685
low_complexity n/a 623 636
disorder n/a 685 689
disorder n/a 693 695
disorder n/a 701 702
Pfam NosD 717 849
disorder n/a 930 932
disorder n/a 964 985

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession B8A5L2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEVGDLPVEL WRLILAYLPL PDLGRCCLVC RAWRELILSL DSTRWRQLCL
50
51
GCPECRHPNW PRRPHLPPAS WREALRQHAL ASRTWTQNGS DLHSSACLHL
100
101
FRRRKDRRVW HVATVAGGGY ESLRGALAVA GPYDKVVLHP GVYEEQVEVA
150
151
LKVPVEIVGM GKLGDVSLLV SFDQQCPTAR LCNVVFMPAW FSPVVYKTSS
200
201
GHVQLDNCNF EGCQLHIRGP GTCQARFCSF AQGSSAHFLG VTISLMDSCE
250
251
FSGGDSASVT VEGPPVSERN WAFKHLVALA KTFTMMTSIG STEMSNQGRK
300
301
DSVSTGSNGN SPFEGINTME DWSKPEVDWE TNWAKQKGGD SLLPGQDGTM
350
351
IEEDGMETSS ESSEEDDDDD LDGEKSTGLK LSYDQHGLAH LSMTDMPNSA
400
401
FPTLLNLSAE LQKDAEARDL AASVQGCLLR RCLLRDGKGG VHLCNHAQAR
450
451
LEANVFRGLN YAVRCIQNAK MVMLRNEVCG CKASGVFLRL SAQGLIAENN
500
501
IHSNGEAGLD IRKGANPIIL CNRIHSGLRS GIVVLGNGRG SIRSNQIYGN
550
551
KEAGVYILFN GNPVVSGNHI FQGLAAGIAV NENGRGLITE NVIRQNQWGG
600
601
ADIRRGGDPV LRNNFICYGY SDGVVVGERG RGLVEGNHIY GNRGCGVWVM
650
651
SSSLPQLIGN HISHNRMYGL AVFCRKDTES AVNREGYRAL QDRDRGERDN
700
701
FNEEGELMAW ESDIDSEDER FSSRRPITVA LVENNCISQN GAVGVFVKSS
750
751
EPLNVVSNMV KSNRGAGVCV IQSAQLTRLV GNCVLCNGWT GVSVDRECRV
800
801
ELRGNGVYGN TCHGVCFRGD GLIVENDVVD NTTGGIRVMD NADVKLFTLI
850
851
YHHEYNLLDP FYYKLGILVR FIPDTVLKIA MITTGWSRAA PPAHAQVLRN
900
901
RVQAVRGYGI SVKQLARGVV QENLVYQSRP TTTKTPIRTN AQNLECVVLN
950
951
NSLLTPRSQA LWALENPPAR PHNSNPSSVT PSTIPAHLAL TMTNRITASV
1000
1001
ESGCHNNGSI FCSIL                                      
1015
 

Show the unformatted sequence.

Checksums:
CRC64:F7E1D60A77F12E9E
MD5:4a5a7607a2b96844f72d1f7bf713061a

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;