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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RPA2_DANRE (B8JKD7)

Summary

This is the summary of UniProt entry RPA2_DANRE (B8JKD7).

Description: DNA-directed RNA polymerase I subunit RPA2
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 1132 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam RNA_pol_Rpb2_1 36 421
low_complexity n/a 154 164
Pfam RNA_pol_Rpb2_2 185 373
Pfam RNA_pol_Rpb2_3 453 518
Pfam RNA_pol_Rpa2_4 561 619
Pfam RNA_pol_Rpb2_6 668 1028
disorder n/a 876 877
disorder n/a 1014 1016
disorder n/a 1018 1022
Pfam RNA_pol_Rpb2_7 1030 1132
low_complexity n/a 1072 1083

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession B8JKD7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDLSKWCNLK TEPSLKHLTE AGFGVPKEKQ SVPVQELVKA HIESFDQAVT
50
51
DGLCRVVEAI PPMEFLYKGD RISLSFVEAI IHTPSVSKGG ISRDLRVFPA
100
101
ECRGRRCTYR AKLVADVSWS VNGVPKGIIK QSLGQMPIMV KSKLCNLHGL
150
151
SPKELLEHHE EAEEMGGYFI VNGIEKVIRL LIMPRRNYPI AVSRPKFKSR
200
201
GQGYTQYAIS MRCVKEEHTA INMNLHYLDN GTVMVNFIYR KELFFLPLGF
250
251
ALKALVDYSD YQIYQELIKG REDNSFYKSC VSEMLRIVMD QGCTTKIKVL
300
301
NYLGERFRVK LNLPEWFTHE QCAHFLLDEC LCIHLKTDVE KFYMLCLMTR
350
351
KLFSFAKQEC MEENPDSPMF HEVLTPGQLY LMFLKEKMEG WLVSVKLALE
400
401
KKPQRVGGLT PDSMTKLFNM GTDLTKAFEY LLATGNLMSK TGLGMLQNSG
450
451
LCVVADKLNF IRYLSHFRCV HRGAAFAKMR TTTVRKLLPE SWGFLCPVHT
500
501
PDGEPCGLMN HMTAHCEIVA PVYPTSTLPG LLCSLGVNAA DGNPGQAYSD
550
551
CYPVILDGAM IGWVEKEVAP SVIESLRRFK VLGEKKVPPW TEIVLVPQTG
600
601
KASLYPGLYL FTTPCRMVRT VRNLSLGKQE LIGIFEQVYL NVGIFEKEIE
650
651
DGVTTHQELF PHSMLSVVAE FIPFSDHNQS PRNMYQCQMS KQTMGFPLHS
700
701
YQYRSDNKLY RLQTPQSPLV RPAMYDHYDV DNYPIGTNAI VAVISYTGYD
750
751
MEDAMIVNKS SWERGFAHGS VYKTEIIDLS EKVKGDDSIV FGVKPGDPKV
800
801
MGKLDADGLP FIGSVLKYGD PFYGYISLNT GQSHVYFYKY QESCVVDNIK
850
851
VCSNETGTGR FKRICVTSRV PRNPTIGDKF ASRHGQKGIL SRLWPAEDMP
900
901
FTESGMSPDI LFNPHGFPSR MTIGMLIESM AGKSASLHGL CHDATPFTFS
950
951
EENSALEHFG ELLKAAGYNY YGTERLYSGL SGLELEADIF IGVVYYQRLR
1000
1001
HMVSDKFQVR TTGARDKVTN QPMGGRNVQG GIRFGEMERD ALLAHGTSFL
1050
1051
LHDRLFNCSD RSVAQVCMDC GSLLSPLLEK PPPNWSATRH RKTICLLCNK
1100
1101
SDSIETVSVP YVFKYFVAEL AAMNIKIKLD VK                   
1132
 

Show the unformatted sequence.

Checksums:
CRC64:A329BA318FA2AA93
MD5:ad6b49563121ccfefba8e009726a6c3f

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;