Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: D3KDM3_CVHSA (D3KDM3)

Summary

This is the summary of UniProt entry D3KDM3_CVHSA (D3KDM3).

Description: Orf1ab polyprotein {ECO:0000313|EMBL:ADC35482.1}
Source organism: SARS coronavirus HKU-39849 (NCBI taxonomy ID )
Length: 7073 amino acids
Reference Proteome: x

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam Nsp1 13 127
Pfam DUF3655 921 989
Pfam Macro 1036 1143
Pfam SUD-M 1327 1469
Pfam Nsp3_PL2pro 1473 1538
Pfam Viral_protease 1541 1859
Pfam NAR 1883 1996
Pfam Corona_NSP4_C 3143 3239
Pfam Peptidase_C30 3269 3559
Pfam nsp7 3837 3919
Pfam nsp8 3920 4117
Pfam nsp9 4118 4230
Pfam NSP10 4239 4361
Pfam Corona_RPol_N 4383 4735
Pfam AAA_30 5568 5711
Pfam NSP11 5905 6497
Pfam NSP16 6777 7073

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession D3KDM3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MESLVLGVNE KTHVQLSLPV LQVRDVLVRG FGDSVEEALS EAREHLKNGT
50
51
CGLVELEKGV LPQLEQPYVF IKRSDALSTN HGHKVVELVA EMDGIQYGRS
100
101
GITLGVLVPH VGETPIAYRN VLLRKNGNKG AGGHSYGIDL KSYDLGDELG
150
151
TDPIEDYEQN WNTKHGSGAL RELTRELNGG AVTRYVDNNF CGPDGYPLDC
200
201
IKDFLARAGK SMCTLSEQLD YIESKRGVYC CRDHEHEIAW FTERSDKSYE
250
251
HQTPFEIKSA KKFDTFKGEC PKFVFPLNSK VKVIQPRVEK KKTEGFMGRI
300
301
RSVYPVASPQ ECNNMHLSTL MKCNHCDEVS WQTCDFLKAT CEHCGTENLV
350
351
IEGPTTCGYL PTNAVVKMPC PACQDPEIGP EHSVADYHNH SNIETRLRKG
400
401
GRTRCFGGCV FAYVGCYNKR AYWVPRASAD IGSGHTGITG DNVETLNEDL
450
451
LEILSRERVN INIVGDFHLN EEVAIILASF SASTSAFIDT IKSLDYKSFK
500
501
TIVESCGNYK VTKGKPVKGA WNIGQQRSVL TPLCGFPSQA AGVIRSIFAR
550
551
TLDAANHSIP DLQRAAVTIL DGISEQSLRL VDAMVYTSDL LTNSVIIMAY
600
601
VTGGLVQQTS QWLSNLLGTT VEKLRPIFEW IEAKLSAGVE FLKDAWEILK
650
651
FLITGVFDIV KGQIQVASDN IKDCVKCFID VVNKALEMCI DQVTIAGAKL
700
701
RSLNLGEVFI AQSKGLYRQC IRGKEQLQLL MPLKAPKEVT FLEGDSHDTV
750
751
LTSEEVVLKN GELEALETPV DSFTNGAIVG TPVCVNGLML LEIKDKEQYC
800
801
ALSPGLLATN NVFRLKGGAP IKGVTFGEDT VWEVQGYKNV RITFELDERV
850
851
DKVLNEKCSV YTVESGTEVT EFACVVAEAV VKTLQPVSDL LTNMGIDLDE
900
901
WSVATFYLFD DAGEENFSSR MYCSFYPPDE EEEDDAECEE EEIDETCEHE
950
951
YGTEDDYQGL PLEFGASAET VRVEEEEEED WLDDTTEQSE IEPEPEPTPE
1000
1001
EPVNQFTGYL KLTDNVAIKC VDIVKEAQSA NPMVIVNAAN IHLKHGGGVA
1050
1051
GALNKATNGA MQKESDDYIK LNGPLTVGGS CLLSGHNLAK KCLHVVGPNL
1100
1101
NAGEDIQLLK AAYENFNSQD ILLAPLLSAG IFGAKPLQSL QVCVQTVRTQ
1150
1151
VYIAVNDKAL YEQVVMDYLD NLKPRVEAPK QEEPPNTEDS KTEEKSVVQK
1200
1201
PVDVKPKIKA CIDEVTTTLE ETKFLTNKLL LFADINGKLY HDSQNMLRGE
1250
1251
DMSFLEKDAP YMVGDVITSG DITCVVIPSK KAGGTTEMLS RALKKVPVDE
1300
1301
YITTYPGQGC AGYTLEEAKT ALKKCKSAFY VLPSEAPNAK EEILGTVSWN
1350
1351
LREMLAHAEE TRKLMPICMD VRAIMATIQR KYKGIKIQEG IVDYGVRFFF
1400
1401
YTSKEPVASI ITKLNSLNEP LVTMPIGYVT HGFNLEEAAR CMRSLKAPAV
1450
1451
VSVSSPDAVT TYNGYLTSSS KTSEEHFVET VSLAGSYRDW SYSGQRTELG
1500
1501
VEFLKRGDKI VYHTLESPVE FHLDGEVLSL DKLKSLLSLR EVKTIKVFTT
1550
1551
VDNTNLHTQL VDMSMTYGQQ FGPTYLDGAD VTKIKPHVNH EGKTFFVLPS
1600
1601
DDTLRSEAFE YYHTLDESFL GRYMSALNHT KKWKFPQVGG LTSIKWADNN
1650
1651
CYLSSVLLAL QQLEVKFNAP ALQEAYYRAR AGDAANFCAL ILAYSNKTVG
1700
1701
ELGDVRETMT HLLQHANLES AKRVLNVVCK HCGQKTTTLT GVEAVMYMGT
1750
1751
LSYDNLKTGV SIPCVCGRDA TQYLVQQESS FVMMSAPPAE YKLQQGTFLC
1800
1801
ANEYTGNYQC GHYTHITAKE TLYRIDGAHL TKMSEYKGPV TDVFYKETSY
1850
1851
TTTIKPVSYK LDGVTYTEIE PKLDGYYKKD NAYYTEQPID LVPTQPLPNA
1900
1901
SFDNFKLTCS NTKFADDLNQ MTGFTKPASR ELSVTFFPDL NGDVVAIDYR
1950
1951
HYSASFKKGA KLLHKPIVWH INQATTKTTF KPNTWCLRCL WSTKPVDTSN
2000
2001
SFEVLAVEDT QGMDNLACES QQPTSEEVVE NPTIQKEVIE CDVKTTEVVG
2050
2051
NVILKPSDEG VKVTQELGHE DLMAAYVENT SITIKKPNEL SLALGLKTIA
2100
2101
THGIAAINSV PWSKILAYVK PFLGQAAITT SNCAKRLAQR VFNNYMPYVF
2150
2151
TLLFQLCTFT KSTNSRIRAS LPTTIAKNSV KSVAKLCLDA GINYVKSPKF
2200
2201
SKLFTIAMWL LLLSICLGSL ICVTAAFGVL LSNFGAPSYC NGVRELYLNS
2250
2251
SNVTTMDFCE GSFPCSICLS GLDSLDSYPA LETIQVTISS YKLDLTILGL
2300
2301
AAEWVLAYML FTKFFYLLGL SAIMQVFFGY FASHFISNSW LMWFIISIVQ
2350
2351
MAPVSAMVRM YIFFASFYYI WKSYVHIMDG CTSSTCMMCY KRNRATRVEC
2400
2401
TTIVNGMKRS FYVYANGGRG FCKTHNWNCL NCDTFCTGST FISDEVARDL
2450
2451
SLQFKRPINP TDQSSYIVDS VAVKNGALHL YFDKAGQKTY ERHPLSHFVN
2500
2501
LDNLRANNTK GSLPINVIVF DGKSKCDESA SKSASVYYSQ LMCQPILLLD
2550
2551
QALVSDVGDS TEVSVKMFDA YVDTFSATFS VPMEKLKALV ATAHSELAKG
2600
2601
VALDGVLSTF VSAARQGVVD TDVDTKDVIE CLKLSHHSDL EVTGDSCNNF
2650
2651
MLTYNKVENM TPRDLGACID CNARHINAQV AKSHNVSLIW NVKDYMSLSE
2700
2701
QLRKQIRSAA KKNNIPFRLT CATTRQVVNV ITTKISLKGG KIVSTCFKLM
2750
2751
LKATLLCVLA ALVCYIVMPV HTLSIHDGYT NEIIGYKAIQ DGVTRDIIST
2800
2801
DDCFANKHAG FDAWFSQRGG SYKNDKSCPV VAAIITREIG FIVPGLPGTV
2850
2851
LRAINGDFLH FLPRVFSAVG NICYTPSKLI EYSDFATSAC VLAAECTIFK
2900
2901
DAMGKPVPYC YDTNLLEGSI SYSELRPDTR YVLMDGSIIQ FPNTYLEGSV
2950
2951
RVVTTFDAEY CRHGTCERSE VGICLSTSGR WVLNNEHYRA LSGVFCGVDA
3000
3001
MNLIANIFTP LVQPVGALDV SASVVAGGII AILVTCAAYY FMKFRRVFGE
3050
3051
YNHVVAANAL LFLMSFTILC LVPAYSFLPG VYSVFYLYLT FYFTNDVSFL
3100
3101
AHLQWFAMFS PIVPFWITAI YVFCISLKHC HWFFNNYLRK RVMFNGVTFS
3150
3151
TFEEAALCTF LLNKEMYLKL RSETLLPLTQ YNRYLALYNK YKYFSGALDT
3200
3201
TSYREAACCH LAKALNDFSN SGADVLYQPP QTSITSAVLQ SGFRKMAFPS
3250
3251
GKVEGCMVQV TCGTTTLNGL WLDDTVYCPR HVICTAEDML NPNYEDLLIR
3300
3301
KSNHSFLVQA GNVQLRVIGH SMQNCLLRLK VDTSNPKTPK YKFVRIQPGQ
3350
3351
TFSVLACYNG SPSGVYQCAM RPNHTIKGSF LNGSCGSVGF NIDYDCVSFC
3400
3401
YMHHMELPTG VHAGTDLEGK FYGPFVDRQT AQAAGTDTTI TLNVLAWLYA
3450
3451
AVINGDRWFL NRFTTTLNDF NLVAMKYNYE PLTQDHVDIL GPLSAQTGIA
3500
3501
VLDMCAALKE LLQNGMNGRT ILGSTILEDE FTPFDVVRQC SGVTFQGKFK
3550
3551
KIVKGTHHWM LLTFLTSLLI LVQSTQWSLF FFVYENAFLP FTLGIMAIAA
3600
3601
CAMLLVKHKH AFLCLFLLPS LATVAYFNMV YMPASWVMRI MTWLELADTS
3650
3651
LSGYRLKDCV MYASALVLLI LMTARTVYDD AARRVWTLMN VITLVYKVYY
3700
3701
GNALDQAISM WALVISVTSN YSGVVTTIMF LARAIVFVCV EYYPLLFITG
3750
3751
NTLQCIMLVY CFLGYCCCCY FGLFCLLNRY FRLTLGVYDY LVSTQEFRYM
3800
3801
NSQGLLPPKS SIDAFKLNIK LLGIGGKPCI KVATVQSKMS DVKCTSVVLL
3850
3851
SVLQQLRVES SSKLWAQCVQ LHNDILLAKD TTEAFEKMVS LLSVLLSMQG
3900
3901
AVDINRLCEE MLDNRATLQA IASEFSSLPS YAAYATAQEA YEQAVANGDS
3950
3951
EVVLKKLKKS LNVAKSEFDR DAAMQRKLEK MADQAMTQMY KQARSEDKRA
4000
4001
KVTSAMQTML FTMLRKLDND ALNNIINNAR DGCVPLNIIP LTTAAKLMVV
4050
4051
VPDYGTYKNT CDGNTFTYAS ALWEIQQVVD ADSKIVQLSE INMDNSPNLA
4100
4101
WPLIVTALRA NSAVKLQNNE LSPVALRQMS CAAGTTQTAC TDDNALAYYN
4150
4151
NSKGGRFVLA LLSDHQDLKW ARFPKSDGTG TIYTELEPPC RFVTDTPKGP
4200
4201
KVKYLYFIKG LNNLNRGMVL GSLAATVRLQ AGNATEVPAN STVLSFCAFA
4250
4251
VDPAKAYKDY LASGGQPITN CVKMLCTHTG TGQAITVTPE ANMDQESFGG
4300
4301
ASCCLYCRCH IDHPNPKGFC DLKGKYVQIP TTCANDPVGF TLRNTVCTVC
4350
4351
GMWKGYGCSC DQLREPLMQS ADASTFLNRV CGVSAARLTP CGTGTSTDVV
4400
4401
YRAFDIYNEK VAGFAKFLKT NCCRFQEKDE EGNLLDSYFV VKRHTMSNYQ
4450
4451
HEETIYNLVK DCPAVAVHDF FKFRVDGDMV PHISRQRLTK YTMADLVYAL
4500
4501
RHFDEGNCDT LKEILVTYNC CDDDYFNKKD WYDFVENPDI LRVYANLGER
4550
4551
VRQSLLKTVQ FCDAMRDAGI VGVLTLDNQD LNGNWYDFGD FVQVAPGCGV
4600
4601
PIVDSYYSLL MPILTLTRAL AAESHMDADL AKPLIKWDLL KYDFTEERLC
4650
4651
LFDRYFKYWD QTYHPNCINC LDDRCILHCA NFNVLFSTVF PPTSFGPLVR
4700
4701
KIFVDGVPFV VSTGYHFREL GVVHNQDVNL HSSRLSFKEL LVYAADPAMH
4750
4751
AASGNLLLDK RTTCFSVAAL TNNVAFQTVK PGNFNKDFYD FAVSKGFFKE
4800
4801
GSSVELKHFF FAQDGNAAIS DYDYYRYNLP TMCDIRQLLF VVEVVDKYFD
4850
4851
CYDGGCINAN QVIVNNLDKS AGFPFNKWGK ARLYYDSMSY EDQDALFAYT
4900
4901
KRNVIPTITQ MNLKYAISAK NRARTVAGVS ICSTMTNRQF HQKLLKSIAA
4950
4951
TRGATVVIGT SKFYGGWHNM LKTVYSDVET PHLMGWDYPK CDRAMPNMLR
5000
5001
IMASLVLARK HNTCCNLSHR FYRLANECAQ VLSEMVMCGG SLYVKPGGTS
5050
5051
SGDATTAYAN SVFNICQAVT ANVNALLSTD GNKIADKYVR NLQHRLYECL
5100
5101
YRNRDVDHEF VDEFYAYLRK HFSMMILSDD AVVCYNSNYA AQGLVASIKN
5150
5151
FKAVLYYQNN VFMSEAKCWT ETDLTKGPHE FCSQHTMLVK QGDDYVYLPY
5200
5201
PDPSRILGAG CFVDDIVKTD GTLMIERFVS LAIDAYPLTK HPNQEYADVF
5250
5251
HLYLQYIRKL HDELTGHMLD MYSVMLTNDN TSRYWEPEFY EAMYTPHTVL
5300
5301
QAVGACVLCN SQTSLRCGAC IRRPFLCCKC CYDHVISTSH KLVLSVNPYV
5350
5351
CNAPGCDVTD VTQLYLGGMS YYCKSHKPPI SFPLCANGQV FGLYKNTCVG
5400
5401
SDNVTDFNAI ATCDWTNAGD YILANTCTER LKLFAAETLK ATEETFKLSY
5450
5451
GIATVREVLS DRELHLSWEV GKPRPPLNRN YVFTGYRVTK NSKVQIGEYT
5500
5501
FEKGDYGDAV VYRGTTTYKL NVGDYFVLTS HTVMPLSAPT LVPQEHYVRI
5550
5551
TGLYPTLNIS DEFSSNVANY QKVGMQKYST LQGPPGTGKS HFAIGLALYY
5600
5601
PSARIVYTAC SHAAVDALCE KALKYLPIDK CSRIIPARAR VECFDKFKVN
5650
5651
STLEQYVFCT VNALPETTAD IVVFDEISMA TNYDLSVVNA RLRAKHYVYI
5700
5701
GDPAQLPAPR TLLTKGTLEP EYFNSVCRLM KTIGPDMFLG TCRRCPAEIV
5750
5751
DTVSALVYDN KLKAHKDKSA QCFKMFYKGV ITHDVSSAIN RPQIGVVREF
5800
5801
LTRNPAWRKA VFISPYNSQN AVASKILGLP TQTVDSSQGS EYDYVIFTQT
5850
5851
TETAHSCNVN RFNVAITRAK IGILCIMSDR DLYDKLQFTS LEIPRRNVAT
5900
5901
LQAENVTGLF KDCSKIITGL HPTQAPTHLS VDIKFKTEGL CVDIPGIPKD
5950
5951
MTYRRLISMM GFKMNYQVNG YPNMFITREE AIRHVRAWIG FDVEGCHATR
6000
6001
DAVGTNLPLQ LGFSTGVNLV AVPTGYVDTE NNTEFTRVNA KPPPGDQFKH
6050
6051
LIPLMYKGLP WNVVRIKIVQ MLSDTLKGLS DRVVFVLWAH GFELTSMKYF
6100
6101
VKIGPERTCC LCDKRATCFS TSSDTYACWN HSVGFDYVYN PFMIDVQQWG
6150
6151
FTGNLQSNHD QHCQVHGNAH VASCDAIMTR CLAVHECFVK RVDWSVEYPI
6200
6201
IGDELRVNSA CRKVQHMVVK SALLADKFPV LHDIGNPKAI KCVPQAEVEW
6250
6251
KFYDAQPCSD KAYKIEELFY SYATHHDKFT DGVCLFWNCN VDRYPANAIV
6300
6301
CRFDTRVLSN LNLPGCDGGS LYVNKHAFHT PAFDKSAFTN LKQLPFFYYS
6350
6351
DSPCESHGKQ VVSDIDYVPL KSATCITRCN LGGAVCRHHA NEYRQYLDAY
6400
6401
NMMISAGFSL WIYKQFDTYN LWNTFTRLQS LENVAYNVVN KGHFDGHAGE
6450
6451
APVSIINNAV YTKVDGIDVE IFENKTTLPV NVAFELWAKR NIKPVPEIKI
6500
6501
LNNLGVDIAA NTVIWDYKRE APAHVSTIGV CTMTDIAKKP TESACSSLTV
6550
6551
LFDGRVEGQV DLFRNARNGV LITEGSVKGL TPSKGPAQAS VNGVTLIGES
6600
6601
VKTQFNYFKK VDGIIQQLPE TYFTQSRDLE DFKPRSQMET DFLELAMDEF
6650
6651
IQRYKLEGYA FEHIVYGDFS HGQLGGLHLM IGLAKRSQDS PLKLEDFIPM
6700
6701
DSTVKNYFIT DAQTGSSKCV CSVIDLLLDD FVEIIKSQDL SVISKVVKVT
6750
6751
IDYAEISFML WCKDGHVETF YPKLQASQAW QPGVAMPNLY KMQRMLLEKC
6800
6801
DLQNYGENAV IPKGIMMNVA KYTQLCQYLN TLTLAVPYNM RVIHFGAGSD
6850
6851
KGVAPGTAVL RQWLPTGTLL VDSDLNDFVS DADSTLIGDC ATVHTANKWD
6900
6901
LIISDMYDPR TKHVTKENDS KEGFFTYLCG FIKQKLALGG SIAVKITEHS
6950
6951
WNADLYKLMG HFSWWTAFVT NVNASSSEAF LIGANYLGKP KEQIDGYTMH
7000
7001
ANYIFWRNTN PIQLSSYSLF DMSKFPLKLR GTAVMSLKEN QINDMIYSLL
7050
7051
EKGRLIIREN NRVVVSSDIL VNN                             
7073
 

Show the unformatted sequence.

Checksums:
CRC64:E6504CAFDC36BC09
MD5:a782af7e1ef470353b6aadb264f15dfe