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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: D4A0U6_RAT (D4A0U6)

Summary

This is the summary of UniProt entry D4A0U6_RAT (D4A0U6).

Description: DNA ligase {ECO:0000256|RuleBase:RU000617}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 911 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam DNA_ligase_A_N 15 208
Pfam DNA_ligase_A_M 248 451
Pfam DNA_ligase_A_C 476 588
disorder n/a 613 632
Pfam BRCT 654 730
Pfam DNA_ligase_IV 750 783
low_complexity n/a 875 887

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession D4A0U6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASSQASRTV AAHVPFADLC STLERIQKGK DRAEKIRHFK EFLDSWRKFH
50
51
DALHKNKKDV PDSFYPAMRL ILPQLERERM AYGIKETMLA KLYIELLNLP
100
101
REGKDAQKLL NYRTPSGARS DAGDFATIAY FVLKPRCLQK GSLTIQKVNE
150
151
LLDLVASNNS GKRKDLVKKS LLQLITQCSA LEQKWLIRMI IKDLKLGVSQ
200
201
HTILSIFHND AVELHNVTTD LEKVCRQLHD PSVGLSDISI TLFSAFRPML
250
251
AAVADVERVE KDMKQQSFYI ETKLDGERMQ MHKDGALYRY FSRNGYNYTD
300
301
QFGESPQEGS LTPFIHNAFK TDVQVCILDG EMMAYNPTTQ TFMQKGVKFD
350
351
IKRMVEDSDL QTCYCVFDVL MVNNKKLGRE TLRKRYDILS STFTPIQGRI
400
401
EIVQKTQAQT KQEVVDALND AIDKREEGIM VKHPLSIYKP DKRGEGWLKI
450
451
KPEYVTGLMD ELDLLIVGGY WGKGSRGGMM SHFLCAVAET PPPGDKPSVF
500
501
HTLCRVGSGY TMKELYDLGL KLAKYWKPFQ RKSPPSCILC GTEKPEVYIE
550
551
PQNSVIVQIK AAEIVPSDMY KTGSTLRFPR IEKIRDDKEW HDCMTLDDLE
600
601
QLRGKASGKL ATKHLHIGDD DEPREKRRKP ISKTKKTIGI IEHLKAPNLS
650
651
NINKVSNVFE DVEFCVMSGL DGYPKPDLEN KIAEFGGYIV QNPGPDTYCV
700
701
IAGSENIRVR NIISSDRHDV VKPEWLLECF KTKTCVPWQP RFMIHMCPST
750
751
KQHFAREYDC YGDSYFVDAD LDQLKEVFLR IKPSEQQTPE EMAPVIADLE
800
801
CRYSWDHSPL SMFRHYTVYL DLYAVINDLS SKIEATRLGV TALELRFRGA
850
851
KVVSRLSEGV SHVIIGEDQR RVSDFKTFRR TLKKKFKILQ ERWVIDSVDK
900
901
CELQEENLYL L                                          
911
 

Show the unformatted sequence.

Checksums:
CRC64:C073CC4616E267B6
MD5:834a9ca8f41ca067a5658f89b9a366f8

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;